Rectosigmoid motility and myoelectric activity in progressive systemic sclerosis.

abstract：BACKGROUND & AIMS:To date, computed tomographic (CT) colonography has been compared with an imperfect test, colonoscopy, and has been mainly assessed in patients with positive screening test results or symptoms. Therefore, the available data may not apply to screening of patients with a personal or family history of co...

journal_title：Gastroenterology

authors： Van Gelder RE,Nio CY,Florie J,Bartelsman JF,Snel P,De Jager SW,Van Deventer SJ,Laméris JS,Bossuyt PM,Stoker J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND & AIMS:There is no clear and point for the response to treatment of gastrointestinal human cytomegalovirus (HCMV) disease. HCMV-DNA quantitation on gastrointestinal biopsy specimens has proven its value for the diagnosis of gastrointestinal HCMV disease in patients with acquired immunodeficiency syndrome (AI...

journal_title：Gastroenterology

authors： Cotte L,Drouet E,Bailly F,Vitozzi S,Denoyel G,Trepo C

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND & AIMS:Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent antiviral agents that might have additive or synergistic antiviral activity in treatment of patients with chronic hepatitis B (CHB). We compared the efficacy and safety of ETV monotherapy with those of a combination of ETV and TDF. ME...

journal_title：Gastroenterology

authors： Lok AS,Trinh H,Carosi G,Akarca US,Gadano A,Habersetzer F,Sievert W,Wong D,Lovegren M,Cohen D,Llamoso C

更新日期：2012-09-01 00:00:00

abstract：:The interrelationship of the effects of antacids and of rising intragastric pH on serum gastrin levels was examined by comparing the effect of three antacids (Mg(OH)2Al(OH)3, and CaCO3), and their nonbuffering chloride compounds (MgCl2, AlCl3, and CaCl2), on serum gastrin and intragastric pH in duodenal ulcer patients...

journal_title：Gastroenterology

authors： Feurle GE

更新日期：1975-01-01 00:00:00

abstract：:To determine the long-term efficacy, safety, and toxicity of omeprazole, we studied 40 patients with Zollinger-Ellison syndrome given omeprazole for 6-51 mo (median 29). The mean daily dose of omeprazole required to control gastric acid secretion was 82 +/- 31 mg. Thirty-one patients required omeprazole once per day. ...

journal_title：Gastroenterology

authors： Maton PN,Vinayek R,Frucht H,McArthur KA,Miller LS,Saeed ZA,Gardner JD,Jensen RT

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND & AIMS:The rate of 12alpha-hydroxylation of bile acid intermediates is believed to determine the ratio of cholic acid (CA) to chenodeoxycholic acid (CDCA) biosynthesis and the overall hydrophobicity of the bile acid pool. The aim of this study was to determine the effects of the level of expression of sterol...

journal_title：Gastroenterology

authors： Pandak WM,Bohdan P,Franklund C,Mallonee DH,Eggertsen G,Björkhem I,Gil G,Vlahcevic ZR,Hylemon PB

更新日期：2001-06-01 00:00:00

abstract：:Hemangioendothelioma of the liver is a rare tumor. A case is reported of a middle-aged woman who presented with hepatomegaly and ascites, and who has been followed for over 12 years. The clinical features, pathological, radiographic, portal hemodynamic, and metabolic changes are presented. ...

journal_title：Gastroenterology

authors： Chowdhury AR,Black M,Lorber SH,Chey WY

更新日期：1977-01-01 00:00:00

abstract：:The present study was undertaken to identify the different amino acid transport pathways present in the human small intestine during the early gestational period. The uptake time courses of neutral (L-leucine, L-alanine, L-methionine), acidic (L-glutamic and D-aspartic acids), basic (L-lysine), and imino (L-proline) a...

journal_title：Gastroenterology

authors： Malo C

更新日期：1991-06-01 00:00:00

abstract：:Spinal cord stimulation is an increasingly popular form of pain treatment. An electrode positioned on the dorsal aspect of the spinal cord at the level of the nerve roots from the painful area stimulates the spinal cord. Current from the electrode is supplied by a pulse generator in the lower anterior abdominal wall. ...

journal_title：Gastroenterology

authors： Kemler MA,Barendse GA,Van Kleef M

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND & AIMS:The accurate identification of inactive (serum HBV-DNA persistently

journal_title：Gastroenterology

authors： Brunetto MR,Oliveri F,Colombatto P,Moriconi F,Ciccorossi P,Coco B,Romagnoli V,Cherubini B,Moscato G,Maina AM,Cavallone D,Bonino F

更新日期：2010-08-01 00:00:00

abstract：:Secretin, substance P, and vasoactive intestinal peptide (VIP) were studied from the immunological point of view using synthetic hormones and their related peptides which were prepared by the conventional method for peptide synthesis. Immunological properties of these hormones were characterized by radioimmunoassays s...

journal_title：Gastroenterology

authors： Yanaihara N,Sakagami M,Sato H,Yammamoto K,Hashimoto T

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of leukotriene (LT) D(4) on intestinal epithelial cells govern events that are involved in cell survival and colon cancer, notably increased expression of cyclooxygenase (COX)-2 and enhanced production of prostaglandin E(2). We investigated possible correlations between distribution of the...

journal_title：Gastroenterology

authors： Ohd JF,Nielsen CK,Campbell J,Landberg G,Löfberg H,Sjölander A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND & AIMS:Cure of Helicobacter pylori infection may lead to complete remission of associated low-grade mucosa-associated lymphoid tissue (MALT) lymphoma in stage EI. This study investigated whether Helicobacter heilmannii infection-associated primary gastric MALT lymphoma will regress after cure of the infectio...

journal_title：Gastroenterology

authors： Morgner A,Lehn N,Andersen LP,Thiede C,Bennedsen M,Trebesius K,Neubauer B,Neubauer A,Stolte M,Bayerdörffer E

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND & AIMS:Interferon-free direct-acting antiviral (DAA) therapies are effective in patients with hepatitis C virus-induced cryoglobulinemia vasculitis (HCV-CV). We analyzed blood samples from patients with HCV-CV before and after DAA therapy to determine mechanisms of these drugs and their effects on cellular i...

journal_title：Gastroenterology

authors： Comarmond C,Garrido M,Pol S,Desbois AC,Costopoulos M,Le Garff-Tavernier M,Si Ahmed SN,Alric L,Fontaine H,Bellier B,Maciejewski A,Rosenzwajg M,Klatzmann D,Musset L,Poynard T,Cacoub P,Saadoun D

更新日期：2017-06-01 00:00:00

abstract：:This study was undertaken to determine the pathogenesis of muscle atrophy that frequently accompanies liver disease. Hepatic injury was induced in rats by giving weekly intragastric doses of carbon tetrachloride (CCl4) in combination with phenobarbital in the drinking water. Muscle protein catabolism was assessed duri...

journal_title：Gastroenterology

authors： Weber FL Jr,Macechko PT,Kelson SR,Karajiannis E,Hassan MO

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND & AIMS:Because alterations of integrin expression in cancers contribute to cancer cell biology, we analyzed the association between the potential for peritoneal dissemination and integrin expression. METHODS:The dissemination potential of 10 human gastric cancer cell lines in mice with severe combined immun...

journal_title：Gastroenterology

authors： Ishii Y,Ochiai A,Yamada T,Akimoto S,Yanagihara K,Kitajima M,Hirohashi S

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND & AIMS:Tumor necrosis factor alpha (TNF-alpha) release plays a pivotal role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) administration in D-galactosamine (GalN)-sensitized mice. Interleukin (IL) 10 is an anti-inflammatory cytokine that inhibits TNF-alpha synthesis and release both...

journal_title：Gastroenterology

authors： Santucci L,Fiorucci S,Chiorean M,Brunori PM,Di Matteo FM,Sidoni A,Migliorati G,Morelli A

更新日期：1996-09-01 00:00:00

abstract：:Fifteen (2.2%) of 693 patients with cystic fibrosis seen over an 18-year period developed clinical hepatic disease. In 13 patients all symptoms were secondary to portal hypertension. Ten had hypersplenism and 6 had variceal bleeding, including 3 who developed both conditions. All 5 patients who survived the initial ep...

journal_title：Gastroenterology

authors： Stern RC,Stevens DP,Boat TF,Doershuk CF,Izant RJ Jr,Matthews LW

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND & AIMS:Early embryogenesis involves cell fate decisions that define the body axes and establish pools of progenitor cells. Development does not stop once lineages are specified; cells continue to undergo specific maturation events, and changes in gene expression patterns lead to their unique physiological fu...

journal_title：Gastroenterology

authors： Direnzo D,Hess DA,Damsz B,Hallett JE,Marshall B,Goswami C,Liu Y,Deering T,Macdonald RJ,Konieczny SF

更新日期：2012-08-01 00:00:00

abstract：:Increased dietary ratios of ω6/ω3 polyunsaturated fatty acids have been implicated in the pathogenesis of Crohn's disease (CD), but epidemiologic data are limited. We investigated whether variants of genes that control polyunsaturated fatty acid metabolism (CYP4F3, FADS1, and FADS2), along with the dietary ratio of ω6...

journal_title：Gastroenterology

authors： Costea I,Mack DR,Lemaitre RN,Israel D,Marcil V,Ahmad A,Amre DK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND & AIMS:Several studies have shown that signaling via the interleukin 23 (IL23) receptor is required for development of colitis. We studied the roles of IL23, dietary factors, alterations to the microbiota, and T cells in the development and progression of colitis in mice. METHODS:All mice were maintained on...

journal_title：Gastroenterology

authors： Chen L,He Z,Iuga AC,Martins Filho SN,Faith JJ,Clemente JC,Deshpande M,Jayaprakash A,Colombel JF,Lafaille JJ,Sachidanandam R,Furtado GC,Lira SA

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND & AIMS:De novo lipogenesis is believed to be involved in oncogenesis. We investigated the role of aberrant lipid biosynthesis in the pathogenesis of human hepatocellular carcinoma (HCC). METHODS:We evaluated expression of enzymes that regulate lipogenesis in human normal liver tissues and HCC and surroundin...

journal_title：Gastroenterology

authors： Calvisi DF,Wang C,Ho C,Ladu S,Lee SA,Mattu S,Destefanis G,Delogu S,Zimmermann A,Ericsson J,Brozzetti S,Staniscia T,Chen X,Dombrowski F,Evert M

更新日期：2011-03-01 00:00:00

abstract：:In dogs with gastric fistulas, intragastric pressure was measured with a flaccid ballon containing 500 ml of water. Graded doses of dopamine caused graded decreases in intragastric pressure. The effect was blocked by pimozide or by metoclopramide but was not significantly affected by phenoxybenzamine, propranolol, gua...

journal_title：Gastroenterology

authors： Valenzuela JE

更新日期：1976-12-01 00:00:00

abstract：:A case of acute hypervitaminosis A complicating viral hepatitis is reported. Twenty days after presenting with hepatitis B, a 42-yr-old vegetarian developed acute hypervitaminosis A in the absence of recent, massive exposure to the vitamin. Findings included headache, confusion, skin desquamation, and hypercalcemia. P...

journal_title：Gastroenterology

authors： Hatoff DE,Gertler SL,Miyai K,Parker BA,Weiss JB

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND & AIMS:A 3-dimensional (3D) culture system for immortalized human hepatocytes (HuS-E/2 cells) recently was shown to support the lifecycle of blood-borne hepatitis C virus (HCV). We used this system to identify proteins that are active during the HCV lifecycle under 3D culture conditions. METHODS:We compared...

journal_title：Gastroenterology

authors： Abe Y,Aly HH,Hiraga N,Imamura M,Wakita T,Shimotohno K,Chayama K,Hijikata M

更新日期：2013-09-01 00:00:00

abstract：:The community of microorganisms within the human gut (or microbiota) is critical to health and functions with a level of complexity comparable to that of an organ system. Alterations of this ecology (or dysbiosis) have been implicated in a number of disease states, and the prototypical example is Clostridium difficile...

journal_title：Gastroenterology

authors： Kelly CR,Kahn S,Kashyap P,Laine L,Rubin D,Atreja A,Moore T,Wu G

更新日期：2015-07-01 00:00:00

abstract：:The site and mechanism of alpha-[5-methyl-3-H]tocopherol absorption was investigated using everted rat small bowel sacs incubated in a micellar medium. Mean plus or minus SE absorption rates of the vitamin at 300 muM incubation solution concentration by proximal, medial, and distal small bowel segments were 2.2 plus o...

journal_title：Gastroenterology

authors： Hollander D,Rim E,Muralidhara KS

更新日期：1975-06-01 00:00:00

abstract：:Human intrinsic factor (IF) is found on the surface of parietal cells at the light microscopic level by immunofluorescence, but there is no direct evidence that IF is synthesized in and secreted from this cell. In order to provide this evidence, IF was localized at the ultrastructural level in human stomach, using an ...

journal_title：Gastroenterology

authors： Levine JS,Nakane PK,Allen RH

更新日期：1980-09-01 00:00:00

abstract：:Non-major histocompatibility complex-restricted cytotoxicity triggered by antibodies to the CD3 component of the human T-cell receptor complex is thought to be an indirect measure of in vivo primed cytotoxic T-cell activity. We have used this technique to examine the lytic activity of freshly isolated T cells from non...

journal_title：Gastroenterology

authors： Shanahan F,Deem R,Nayersina R,Leman B,Targan S

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:It was recently reported that ventromedial hypothalamic (VMH) lesions produced an increase in gastrointestinal DNA content in rats. In the present study, the mechanism of this alteration was examined. METHODS:The DNA content and synthesis after VMH lesioning in rat gastrointestinal tracts were determined. ...

journal_title：Gastroenterology

authors： Kiba T,Tanaka K,Endo O,Inoue S

更新日期：1993-02-01 00:00:00