Integrin alpha6beta4 as a suppressor and a predictive marker for peritoneal dissemination in human gastric cancer.

abstract：:The effects of calcium channel blockers on water transport in the rat ileum and distal colon were studied in vivo using the single-pass perfusion technique. Parenteral but not intraluminal verapamil, and parenteral nifedipine increased ileal water absorption, with effects lasting at least 60 min. In contrast, i.p. ver...

journal_title：Gastroenterology

authors： Donowitz M,Levin S,Powers G,Elta G,Cohen P,Cheng H

更新日期：1985-10-01 00:00:00

abstract：:Adverse reactions to food that result in gastrointestinal symptoms are common in the general population; while only a minority of such individuals will have symptoms due to immunologic reactions to foods, gastrointestinal food allergies do exist in both children and adults. These immune reactions are mediated by immun...

journal_title：Gastroenterology

authors： Bischoff S,Crowe SE

更新日期：2005-04-01 00:00:00

abstract：:Rising trends in the incidence and mortality of early-onset CRC in those who are ages less than 50 years have been well-established. These trends have spurred intense investigation focused on elucidating the epidemiology and characteristics of early-onset CRC, as well on identifying strategies for early detection and ...

journal_title：Gastroenterology

authors： Burnett-Hartman AN,Lee JK,Demb J,Gupta S

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND/AIMS:The gastrointestinal tract is a major target of insulinlike growth factor (IGF) I. IGF-I binds to two different receptors and to binding proteins (IGFBPs), which act as carriers and mediators. This study investigated the regulation of IGF-I binding sites in rat colitis. METHODS:Colitis was induced by c...

journal_title：Gastroenterology

authors： Zeeh JM,Hoffmann P,Sottili M,Eysselein VE,McRoberts JA

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND & AIMS:Cell-mediated immunity is a feature of Crohn's disease (CD). The heterodimer interleukin (IL)-12, produced by phagocytes, induces T-cell cytokines, primarily interferon (IFN)-gamma. This study examined whether CD lamina propria mononuclear cells (LPMCs) express and release bioactive IL-12. METHODS:LP...

journal_title：Gastroenterology

authors： Monteleone G,Biancone L,Marasco R,Morrone G,Marasco O,Luzza F,Pallone F

更新日期：1997-04-01 00:00:00

abstract：:This study examines the effects of endotoxin on intestinal water and electrolyte transport in adult male rats. Endotoxin (1.55 mg/kg, intravenously) reduced in vivo colonic saline absorption 61% in 1 hour. In vitro unidirectional and net 22Na and 36Cl fluxes showed that endotoxin significantly decreased net colonic 22...

journal_title：Gastroenterology

authors： Ciancio MJ,Vitiritti L,Dhar A,Chang EB

更新日期：1992-11-01 00:00:00

abstract：:Median nerve somatosensory evoked potentials were recorded from 33 patients with various degrees of hepatic failure and from 10 age-matched controls. Within 20 ms poststimulation, one negative peak (N13) could be recorded from the middle of the back of the patient's neck at the C2 vertebral level. Within 150 ms, three...

journal_title：Gastroenterology

authors： Yang SS,Chu NS,Liaw YF

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND & AIMS:The ubiquitous cross-linking enzyme tissue transglutaminase (TG2) has been implicated in irreversible collagen stabilization in liver fibrosis, although functional evidence is lacking. We studied the contribution of TG2 to hepatic fibrotic matrix stability, as well as liver fibrosis progression and re...

journal_title：Gastroenterology

authors： Popov Y,Sverdlov DY,Sharma AK,Bhaskar KR,Li S,Freitag TL,Lee J,Dieterich W,Melino G,Schuppan D

更新日期：2011-05-01 00:00:00

abstract：:Plasma levels of gastrinlike, somatostatinlike, and cholecystokininlike immunoreactivity were determined by radioimmunoassay in peripheral blood from 11 beagles during pregnancy and in response to suckling during lactation. Cholecystokinin was determined in pooled and in individual plasma samples after separation of c...

journal_title：Gastroenterology

authors： Linden A,Eriksson M,Carlquist M,Uvnäs-Moberg K

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND & AIMS:Chemoembolization is one of several standards of care treatment for hepatocellular carcinoma (HCC). Radioembolization with Yttrium-90 microspheres is a novel, transarterial approach to radiation therapy. We performed a comparative effectiveness analysis of these therapies in patients with HCC. METHOD...

journal_title：Gastroenterology

authors： Salem R,Lewandowski RJ,Kulik L,Wang E,Riaz A,Ryu RK,Sato KT,Gupta R,Nikolaidis P,Miller FH,Yaghmai V,Ibrahim SM,Senthilnathan S,Baker T,Gates VL,Atassi B,Newman S,Memon K,Chen R,Vogelzang RL,Nemcek AA,Resnick SA

更新日期：2011-02-01 00:00:00

abstract：:Regional specific antibodies and chromatography were used to analyze the distributions and molecular forms of peptide histidine isoleucine (PHI) and vasoactive intestinal peptide (VIP) in the porcine intestine. Both peptides were present along the entire length of the intestine, the highest concentrations occurring in...

journal_title：Gastroenterology

authors： Yiangou Y,Christofides ND,Blank MA,Yanaihara N,Tatemoto K,Bishop AE,Polak JM,Bloom SR

更新日期：1985-09-01 00:00:00

abstract：:To determine the fate of exogenous epidermal growth factor (EGF) in regenerating liver, 125I-labeled EGF was injected into rat portal veins at various times after 70% hepatectomy. Epidermal growth factor was taken up by the liver remnant at all time points studied (0, 4, 8, 16, and 36 h), but at 8 h after hepatectomy ...

journal_title：Gastroenterology

authors： Raper SE,Burwen SJ,Barker ME,Jones AL

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Patients with celiac disease have immunoglobulin (Ig) M antibodies and IgA antigliadin antibody in gut secretions; this pattern of intestinal immunity may be a marker of latent celiac disease. Its frequency in patients referred for jejunal biopsy has been examined. METHODS:Serum IgG and IgA antigliadin anti...

journal_title：Gastroenterology

authors： Arranz E,Ferguson A

更新日期：1993-05-01 00:00:00

abstract：:A newly recognized clinical and morphologic pattern of acute alcoholic liver disease is described. Twenty-one patients, having the hepatic morphologic features of alcoholic foamy degeneration, were retrospectively analyzed. All patients had a significant history of chronic alcoholism. Jaundice and hepatomegaly were us...

journal_title：Gastroenterology

authors： Uchida T,Kao H,Quispe-Sjogren M,Peters RL

更新日期：1983-04-01 00:00:00

abstract：:Plasma amino acid abnormalities are common in alcoholics, but the respective role of alcoholism, nutrition, and liver injury in producing these abnormalities is unknown. To elucidate this question, amino acids were measured in 56 alcoholics and 32 nonalcoholics with liver disease, and in an experimental model of alcoh...

journal_title：Gastroenterology

authors： Shaw S,Lieber CS

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND & AIMS:Inflammation is created by the movement of leukocytes toward soluble attractants (chemokines). The aim of this study was to identify the chemokines that attract intestinal lymphocytes. METHODS:Intraepithelial and lamina propria lymphocytes were isolated from human jejunal mucosa of healthy individual...

journal_title：Gastroenterology

authors： Ebert EC

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND & AIMS:Entecavir demonstrated superior benefit to lamivudine at 48 weeks in nucleoside-naive patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB). We evaluated continued entecavir and lamivudine treatment through 96 weeks. METHODS:709 HBeAg-positive CHB patients were randomized to ...

journal_title：Gastroenterology

authors： Gish RG,Lok AS,Chang TT,de Man RA,Gadano A,Sollano J,Han KH,Chao YC,Lee SD,Harris M,Yang J,Colonno R,Brett-Smith H

更新日期：2007-11-01 00:00:00

abstract：:A novel water-soluble dopamine-2 antagonist, N-[4-[2-(dimethylamino) ethoxy]benzyl]-3,4-dimethoxybenzamide hydrochloride (HSR-803) was synthesized and assayed for its gastrointestinal smooth muscle stimulating activity in vivo and in vitro. In the in vivo study, gastrointestinal contractile activity was measured by me...

journal_title：Gastroenterology

authors： Iwanaga Y,Miyashita N,Morikawa K,Mizumoto A,Kondo Y,Itoh Z

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND & AIMS:The cyclic adenosine monophosphate (cAMP) and Ca(2+) signaling pathways synergize to regulate many physiological functions. However, little is known about the mechanisms by which these pathways interact. We investigated the synergy between these signaling pathways in mouse pancreatic and salivary glan...

journal_title：Gastroenterology

authors： Park S,Shcheynikov N,Hong JH,Zheng C,Suh SH,Kawaai K,Ando H,Mizutani A,Abe T,Kiyonari H,Seki G,Yule D,Mikoshiba K,Muallem S

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Antibodies directed against oligomannose sequences alpha-1,3 Man (alpha-1,2 Man alpha-1,2 Man)(n) (n = 1 or 2), termed anti-Saccharomyces cerevisiae antibodies (ASCAs) are markers of Crohn's disease (CD). S. cerevisiae mannan, which expresses these haptens, is used to detect ASCA, but the exact immu...

journal_title：Gastroenterology

authors： Standaert-Vitse A,Jouault T,Vandewalle P,Mille C,Seddik M,Sendid B,Mallet JM,Colombel JF,Poulain D

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND & AIMS:Thromboxane levels correlate with severity of liver injury in rats given alcohol. The aim of this study was to evaluate the effect of thromboxane inhibitors on pathological changes in experimental alcoholic liver disease. METHODS:Male Wistar rats were given a liquid diet and ethanol intragastrically ...

journal_title：Gastroenterology

authors： Nanji AA,Khwaja S,Rahemtulla A,Miao L,Zhao S,Tahan SR

更新日期：1997-01-01 00:00:00

abstract：:A new model of an acute bleeding gastric ulcer with a single bleeding artery in its base has been developed. A suction ulcer defect is created over a large, submucosal artery. Small bleeding marginal vessels are electrocoagulated with a fine-tipped bipolar forceps. The artery in the base of the ulcer is dissected free...

journal_title：Gastroenterology

authors： Dennis MB,Silverstein FE,Gilbert DA,Peoples JE

更新日期：1981-06-01 00:00:00

abstract：:This document presents the official recommendations of the American Gastroenterological Association (AGA) Institute on "Use of Gastrointestinal Medications in Pregnancy." It was approved by the Clinical Practice and Economics Committee on February 22, 2006, and by the AGA Institute Governing Board on April 20, 2006. ...

journal_title：Gastroenterology

authors： Mahadevan U,Kane S

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND & AIMS:Prediction of relapse of inflammatory bowel disease has important implications for therapeutic strategies. We assessed whether measurement of intestinal permeability and inflammation could predict relapse of inflammatory bowel disease (IBD). METHODS:Forty-three patients with Crohn's disease (CD) and ...

journal_title：Gastroenterology

authors： Tibble JA,Sigthorsson G,Bridger S,Fagerhol MK,Bjarnason I

更新日期：2000-07-01 00:00:00

abstract：:In humans and most other species, a decline in pH of gallbladder contents occurs during the concentration of bile. Recent in vitro studies in rabbit, guinea pig, and Necturus gallbladders have strongly suggested mucosal H+ secretion during sodium reabsorption, presumably representing a Na+/H+ exchange. The present in ...

journal_title：Gastroenterology

authors： Rege RV,Moore EW

更新日期：1987-02-01 00:00:00

abstract：:The site and mechanism of alpha-[5-methyl-3-H]tocopherol absorption was investigated using everted rat small bowel sacs incubated in a micellar medium. Mean plus or minus SE absorption rates of the vitamin at 300 muM incubation solution concentration by proximal, medial, and distal small bowel segments were 2.2 plus o...

journal_title：Gastroenterology

authors： Hollander D,Rim E,Muralidhara KS

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND & AIMS:Activated recombinant factor VII (rFVIIa) has been shown to be effective in correcting prolonged prothrombin time (PT) in cirrhotic patients. The main objective of this study was to evaluate the effect of 4 (5, 20, 80, and 120 microg/kg) doses of rFVIIa on correction of PT and the time to achieve hemo...

journal_title：Gastroenterology

authors： Jeffers L,Chalasani N,Balart L,Pyrsopoulos N,Erhardtsen E

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatitis B virus (HBV) and hepatitis C virus (HCV) can be transmitted during administration of intravenous anesthesia when medication vials are used for multiple patients using incorrect technique. We investigated an outbreak of acute HBV and HCV infections among patients who received anesthesia duri...

journal_title：Gastroenterology

authors： Gutelius B,Perz JF,Parker MM,Hallack R,Stricof R,Clement EJ,Lin Y,Xia GL,Punsalang A,Eramo A,Layton M,Balter S

更新日期：2010-07-01 00:00:00

abstract：:Fc receptor-mediated clearance of immunoglobulin G-coated autologous erythrocytes was studied in patients with primary biliary cirrhosis (n = 14), alcoholic liver cirrhosis (n = 5) and healthy reference individuals (n = 14). The mean half-life of the sensitized erythrocytes was significantly prolonged in patients with...

journal_title：Gastroenterology

authors： Ekdahl KN,Lööf L,Nyberg A,Nilsson UR,Nilsson B

更新日期：1991-10-01 00:00:00

abstract：:To determine the frequency and significance of alpha-fetoprotein elevation in severe hepatitis B surface antigen-negative chronic active hepatitis, 558 serum samples obtained from 83 patients were tested by an immunoenzymometric assay. All patients received corticosteroids and sampling occurred at 6-12-mo intervals du...

journal_title：Gastroenterology

authors： Czaja AJ,Beaver SJ,Wood JR,Klee GG,Go VL

更新日期：1987-10-01 00:00:00