Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectives.

Abstract:

:Adverse reactions to food that result in gastrointestinal symptoms are common in the general population; while only a minority of such individuals will have symptoms due to immunologic reactions to foods, gastrointestinal food allergies do exist in both children and adults. These immune reactions are mediated by immunoglobulin E-dependent and -independent mechanisms involving mast cells, eosinophils, and other immune cells, but the complexity of the underlying mechanisms of pathogenesis have yet to be fully defined. Knowledge of the spectrum of adverse reactions to foods that affect the digestive system, including gastrointestinal food allergy, is essential to correctly diagnose and manage the subset of patients with immunologically mediated adverse reactions to foods. Potentially fatal reactions to food necessitate careful instruction and monitoring on the part of health care workers involved in the care of individuals at risk of anaphylaxis. New methods of diagnosis and novel strategies for treatment, including immunologic modulation and the development of hypoallergenic foods, are exciting developments in the field of food allergy.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Bischoff S,Crowe SE

doi

10.1053/j.gastro.2004.08.015

keywords:

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

1089-113

issue

4

eissn

0016-5085

issn

1528-0012

pii

S0016508504014052

journal_volume

128

pub_type

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