Hemangioendotheliomatosis of the liver. A 12-year follow-up.

abstract：:Plasma amino acid abnormalities are common in alcoholics, but the respective role of alcoholism, nutrition, and liver injury in producing these abnormalities is unknown. To elucidate this question, amino acids were measured in 56 alcoholics and 32 nonalcoholics with liver disease, and in an experimental model of alcoh...

journal_title：Gastroenterology

authors： Shaw S,Lieber CS

更新日期：1978-04-01 00:00:00

abstract：:This study examines restitution of the gastric surface epithelium at luminal pH 1 after damage to the gastric mucosa by instillation of 2 M NaCl for 10 min. After mucosal damage, potential difference decreased to zero and H+ back-diffusion increased. Gastric blood flow increased after exposure to 2 M NaCl, irrespectiv...

journal_title：Gastroenterology

authors： Grönbech JE,Grong K,Varhaug JE,Lekven J,Svanes K

更新日期：1987-10-01 00:00:00

abstract：:Several studies suggest that bile salts are transported from the basolateral to the canalicular membrane of hepatocytes by a vesicular pathway, possibly in part via the Golgi complex. To test this hypothesis, the present study examined, in the perfused rat liver, the influence of the Na+ ionophore monensin on the bili...

journal_title：Gastroenterology

authors： Reynier MO,Abou Hashieh I,Crotte C,Carbuccia N,Richard B,Gérolami A

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND/AIMS:Carbonic anhydrase activity plays a role in electrolyte transport in many tissues. This study examined the effect of the carbonic anhydrase inhibitor acetazolamide on human basal and prostaglandin E2- and acid-stimulated duodenal mucosal bicarbonate secretion and transmucosal electrical potential differ...

journal_title：Gastroenterology

authors： Knutson TW,Koss MA,Hogan DL,Isenberg JI,Knutson L

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND & AIMS:Gain-of-function mutations in the KIT receptor tyrosine kinase gene and rare mutations in the platelet-derived growth factor receptor alpha (PDGFRA) gene are important events in gastrointestinal stromal tumor (GIST) development. Different mutations are reportedly associated with distinctive phenotypes...

journal_title：Gastroenterology

authors： Andersson J,Bümming P,Meis-Kindblom JM,Sihto H,Nupponen N,Joensuu H,Odén A,Gustavsson B,Kindblom LG,Nilsson B

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND & AIMS:Congenital sucrase-isomaltase deficiency (CSID) is an autosomal recessive human disorder characterized by reduced activities of the brush border enzyme sucrase-isomaltase (SI). Here, we elucidate the pathogenesis of a new variant of CSID at the cellular and molecular level. METHODS:Assessment of the ...

journal_title：Gastroenterology

authors： Ritz V,Alfalah M,Zimmer KP,Schmitz J,Jacob R,Naim HY

更新日期：2003-12-01 00:00:00

abstract：:Three structurally related peptides, ovine corticotropin-releasing factor, sauvagine, and urotensin I are selective mesenteric vasodilators in dogs. To assess the possible benefit of these peptides in nonocclusive mesenteric ischemia, they were compared with a nonselective vasodilator, sodium nitroprusside, in the ane...

journal_title：Gastroenterology

authors： MacCannell KL,Newton CA,Lederis K,Rivier J,Tiffany M

更新日期：1986-03-01 00:00:00

abstract：:To determine if changes in intestinal motility occur during pregnancy, we studied small intestinal myoelectric activity, using monopolar electrodes, in fasted pregnant rats from day 12 to day 18 of the 22-day gestation period. We also studied fasting myoelectric activity in postpartum, nonpregnant, and castrate female...

journal_title：Gastroenterology

authors： Scott LD,Lester R,Van Thiel DH,Wald A

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND & AIMS:We assessed the risk of ulcers with low-dose aspirin and the interaction of low-dose aspirin with a COX-2 selective inhibitor in a double-blind trial that compared placebo, low-dose aspirin, rofecoxib + low-dose aspirin, and ibuprofen. METHODS:Osteoarthritis patients > or =50 years of age without ulc...

journal_title：Gastroenterology

authors： Laine L,Maller ES,Yu C,Quan H,Simon T

更新日期：2004-08-01 00:00:00

abstract：:Short-chain (C2-C5) fatty acids account for 60%-70% of the anions in the colon. Acetate (C2) is nontoxic in contrast to C(3)4-C5 fatty acids (propionate, butyrate, isobutyrate, valerate, and isovalerate), which induce coma in animals and may be important in the pathogenesis of hepatic coma in humans. An in-vitro fecal...

journal_title：Gastroenterology

authors： Mortensen PB,Holtug K,Bonnén H,Clausen MR

更新日期：1990-02-01 00:00:00

abstract：:Fetal bile salt metabolism was assessed by the intravenous infusion of e114C]cholate into 6 monkey fetuses. The placental transfer, fetal plasma clearance, and fetal hepatic excretion of the administered radiolabeled bile salt were measured. Placental transfer averaged 30% of the injected dose, while biliary excretion...

journal_title：Gastroenterology

authors： Little JM,Smallwood RA,Lester R,Piasecki GJ,Jackson BT

更新日期：1975-12-01 00:00:00

abstract：:Chronic liver diseases (CLDs), due to chronic hepatitis C; hepatitis B; nonalcoholic fatty liver diseases (NAFLD); and alcoholic liver disease, are a leading cause of morbidity and mortality globally. Early identification of patients with cirrhosis at high risk of progression to liver-related complications may facilit...

journal_title：Gastroenterology

authors： Singh S,Muir AJ,Dieterich DT,Falck-Ytter YT

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND & AIMS:Noninvasive methods are needed to identify clinically significant portal hypertension (CSPH) and esophageal varices (EVs) in patients with compensated cirrhosis. We looked for markers of the presence of CSPH and EVs in patients with cirrhosis. METHODS:We performed a cross-sectional study that include...

journal_title：Gastroenterology

authors： Berzigotti A,Seijo S,Arena U,Abraldes JG,Vizzutti F,García-Pagán JC,Pinzani M,Bosch J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Earlier studies have suggested that patients with hemochromatosis have poor post-transplantation survival. We aimed to compare patients with hemochromatosis to those with other causes of liver disease with regard to post-transplantation survival. METHODS:We compared the post-transplant survival of ...

journal_title：Gastroenterology

authors： Yu L,Ioannou GN

更新日期：2007-08-01 00:00:00

abstract：:The effects of corticosteroid treatment on mucosal mast cells in rat jejunal mucosa were examined. Rats previously infected with Nippostrongylus brasiliensis received a single IP injection of 1 mg dexamethasone. Three hours later, one third of mucosal mast cells demonstrated minor granular changes (fusion or periphera...

journal_title：Gastroenterology

authors： Soda K,Kawabori S,Perdue MH,Bienenstock J

更新日期：1991-04-01 00:00:00

abstract：:Evidence-based medicine combines clinical expertise and the best available evidence from systematic research to aid decision making in patient care. Levels of evidence can be graded from I to V, with level I, the strongest, coming from large randomized controlled trials (RCTs). When a definitive RCT has not been perfo...

journal_title：Gastroenterology

authors： Howden CW

更新日期：1997-12-01 00:00:00

abstract：:Altered gallbladder motility could predispose to, or result from, gallstone formation and could also explain the alleged relief of biliary colic seen during bile acid therapy. Therefore, in 14 controls, 25 patients with radiolucent gallstones, and 14 patients with radiopaque gallstones, we used two techniques to measu...

journal_title：Gastroenterology

authors： Forgacs IC,Maisey MN,Murphy GM,Dowling RH

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND & AIMS:The incidence of anal cancer is higher in patients with anal canal condyloma, a sexually transmitted disease, than in the general population. We determined the prevalence of anal dysplasia and cancer in patients with anal canal condyloma with respect to human immunodeficiency virus (HIV) status, immun...

journal_title：Gastroenterology

authors： Sobhani I,Vuagnat A,Walker F,Vissuzaine C,Mirin B,Hervatin F,Marmuse JP,Crémieux AC,Carbon C,Henin D,Lehy T,Mignon M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Patients with celiac disease have immunoglobulin (Ig) M antibodies and IgA antigliadin antibody in gut secretions; this pattern of intestinal immunity may be a marker of latent celiac disease. Its frequency in patients referred for jejunal biopsy has been examined. METHODS:Serum IgG and IgA antigliadin anti...

journal_title：Gastroenterology

authors： Arranz E,Ferguson A

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND/AIMS:Reflex relaxation is a mechanism whereby the colon can show short-term dilatation in the absence of mechanical obstruction. This study investigated the tonic response of the canine colon to ileal distention and its pharmacological control. METHODS:In four dogs, the tone of the proximal colon was record...

journal_title：Gastroenterology

authors： Basilisco G,Phillips SF

更新日期：1994-03-01 00:00:00

abstract：:Intestinal microbes regulate metabolic function and energy balance; an altered microbial ecology is believed to contribute to the development of several metabolic diseases. Relative species abundance and metabolic characteristics of the intestinal microbiota change substantially in those who are obese or have other me...

journal_title：Gastroenterology

authors： Nieuwdorp M,Gilijamse PW,Pai N,Kaplan LM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND & AIMS:There is controversy over the optimal management strategy for patients with acute pancreatitis (AP). Studies have shown a hospital volume benefit for in-hospital mortality after surgery, and we examined whether a similar mortality benefit exists for patients admitted with AP. METHODS:Using the Nation...

journal_title：Gastroenterology

authors： Singla A,Simons J,Li Y,Csikesz NG,Ng SC,Tseng JF,Shah SA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of trypsin on pancreatic ductal epithelial cells (PDECs) vary among species and depend on the localization of proteinase-activated receptor 2 (PAR-2). We compared PAR-2 localization in human and guinea-pig PDECs, and used isolated guinea pig ducts to study the effects of trypsin and a PAR-...

journal_title：Gastroenterology

authors： Pallagi P,Venglovecz V,Rakonczay Z Jr,Borka K,Korompay A,Ozsvári B,Judák L,Sahin-Tóth M,Geisz A,Schnúr A,Maléth J,Takács T,Gray MA,Argent BE,Mayerle J,Lerch MM,Wittmann T,Hegyi P

更新日期：2011-12-01 00:00:00

abstract：:Disseminated cytomegalovirus infection occurs predominantly in immunocompromised hosts. Involvement of the gastrointestinal tract in the acquired immunodeficiency syndrome is frequent, but to our knowledge there is only one report of involvement of the appendix. In this study, a patient with a history of the acquired ...

journal_title：Gastroenterology

authors： Valerdiz-Casasola S,Pardo-Mindan FJ

更新日期：1991-07-01 00:00:00

abstract：:The presence of receptors for insulinlike growth factor I and II in human colonic epithelium is demonstrated. Scatchard analysis of binding data obtained with 125I-insulinlike growth factor I showed an insulinlike growth factor I receptor with a dissociation constant of 8.6 nM and a binding capacity of 0.8 pmol/mg mem...

journal_title：Gastroenterology

authors： Rouyer-Fessard C,Gammeltoft S,Laburthe M

更新日期：1990-03-01 00:00:00

abstract：:The effect of thyroidectomy on the activity of liver alcohol dehydrogenase and on the rate of ethanol elimination was determined in the rat. Thyroidectomy resulted in a marked increase in liver alcohol dehydrogenase activity. Three isoenzymes of alcohol dehydrogenase activity were demonstrated in thyroidectomized anim...

journal_title：Gastroenterology

authors： Mezey E,Potter JJ

更新日期：1981-03-01 00:00:00

abstract：:To evaluate the effect of aging upon the small intestine, the distribution, content, and concentration of epithelial cell enzymes at different levels along the crypt-villus column were measured in aging and young adult, male, Fisher 344 rats. Specific activities of sucrase, maltase, lactase, and adenosine deaminase in...

journal_title：Gastroenterology

authors： Holt PR,Tierney AR,Kotler DP

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND & AIMS:Caco-2 cells have been used extensively to elucidate events involved in intestinal cell proliferation and differentiation. Because individual isoforms of protein kinase C (PKC) and p21waf1, a cyclin-dependent kinase inhibitor, may regulate these processes, their role(s) on the growth and differentiati...

journal_title：Gastroenterology

authors： Abraham C,Scaglione-Sewell B,Skarosi SF,Qin W,Bissonnette M,Brasitus TA

更新日期：1998-03-01 00:00:00

abstract：:Transient relaxation of the lower esophageal sphincter (LES) is observed fairly frequently during prolonged continuous monitoring of the LES. The aim of this study was to test whether the presence of a catheter in the pharynx through the stimulation of mechanoreceptors may induce transient LES relaxation. LES and esop...

journal_title：Gastroenterology

authors： Mittal RK,Stewart WR,Schirmer BD

更新日期：1992-10-01 00:00:00

abstract：:Congenital esophageal stenosis (CES) is a rare disorder with narrowed esophageal lumen that presents as dysphagia from childhood and that is often associated with tracheobronchial remnants or webs. The pathogenesis of CES is unknown. The aim of this study was to examine the histological and immunohistochemical feature...

journal_title：Gastroenterology

authors： Singaram C,Sweet MA,Gaumnitz EA,Cameron AJ,Camilleri M

更新日期：1995-07-01 00:00:00