An Italian Neurorehabilitation Hospital Facing the SARS-CoV-2 Pandemic: Data From 1207 Patients and Workers.

abstract：:The electrophysiological EEG features such as high frequency oscillations, spikes and functional connectivity are often used for delineation of epileptogenic tissue and study of the normal function of the brain. The epileptogenic activity is also known to be suppressed by cognitive processing. However, differences bet...

journal_title：Frontiers in neurology

authors： Cimbalnik J,Pail M,Klimes P,Travnicek V,Roman R,Vajcner A,Brazdil M

更新日期：2020-10-27 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:Background: Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of many neurological diseases, including multiple sclerosis (MS). Objective: To search the level of MMPs in the cerebrospinal fluid (CSF) of MS patien...

journal_title：Frontiers in neurology

authors： Castellazzi M,Ligi D,Contaldi E,Quartana D,Fonderico M,Borgatti L,Bellini T,Trentini A,Granieri E,Fainardi E,Mannello F,Pugliatti M

更新日期：2018-12-18 00:00:00

abstract：:Background: Intracranial atherosclerotic stenosis (ICAS) is an important cause of ischemic stroke. In Asians, intracranial atherosclerotic disease leads to 33-50% of ischemic events. At present, treatment with medication vs. endovascular therapy (EVT) for symptomatic ICAS (sICAS) patients is still debatable. The clini...

journal_title：Frontiers in neurology

authors： Zhang J,Zhang K,Jia B,Qi Z,Mo D,Ma N,Gao F,Miao Z

更新日期：2020-11-06 00:00:00

abstract：:The endothelium is a thin monolayer of specialized cells that lines the luminal wall of blood vessels and constitutes the critical innermost portion of the physical barrier between the blood and the brain termed the blood-brain barrier (BBB). Aberrant changes in the endothelium occur in many neuropathological states, ...

journal_title：Frontiers in neurology

authors： Lutton EM,Farney SK,Andrews AM,Shuvaev VV,Chuang GY,Muzykantov VR,Ramirez SH

更新日期：2019-06-06 00:00:00

abstract：:Children and adolescent athletes are at a higher risk for concussion than adults, and also experience longer recovery times and increased associated symptoms. It has also recently been demonstrated that multiple, seemingly mild concussions may result in exacerbated and prolonged neurological deficits. Objective assess...

journal_title：Frontiers in neurology

authors： Kiefer AW,Barber Foss K,Reches A,Gadd B,Gordon M,Rushford K,Laufer I,Weiss M,Myer GD

更新日期：2015-11-20 00:00:00

abstract：:Stroke is becoming one of the leading causes of adult disability and death in sub-Saharan African countries. The aim of the present study is to provide an up-to-date account of the clinical and demographic characteristics of patients with stroke admitted to the University of Gondar College of Medicine and Health Scien...

journal_title：Frontiers in neurology

authors： Baye M,Hintze A,Gordon-Murer C,Mariscal T,Belay GJ,Gebremariam AA,Hughes CML

更新日期：2020-05-19 00:00:00

abstract：:Despite extensive research, the functions of the basal ganglia (BG) in movement control have not been fully understood. Eye movements, particularly saccades, are convenient indicators of BG function. Here, we review the main oculomotor findings reported in Parkinson's disease (PD) and genetic parkinsonian syndromes. P...

journal_title：Frontiers in neurology

authors： Pretegiani E,Optican LM

更新日期：2017-11-09 00:00:00

abstract：:Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is the first example of a learning health system in multiple sclerosis (MS). This paper describes the initial implementation of MS PATHS and initial patient characteristics. Methods: MS PATHS is an ongoing initiative conducted...

journal_title：Frontiers in neurology

authors： Mowry EM,Bermel RA,Williams JR,Benzinger TLS,de Moor C,Fisher E,Hersh CM,Hyland MH,Izbudak I,Jones SE,Kieseier BC,Kitzler HH,Krupp L,Lui YW,Montalban X,Naismith RT,Nicholas JA,Pellegrini F,Rovira A,Schulze M,Tacke

更新日期：2020-08-07 00:00:00

abstract：:Objective: To investigate the effects of low frequency transcranial magnetic stimulation (LF-rTMS) combined with motor imagery (MI) on upper limb motor function during stroke rehabilitation. Background: Hemiplegic upper extremity activity obstacle is a common movement disorder after stroke. Compared with a single inte...

journal_title：Frontiers in neurology

authors： Pan W,Wang P,Song X,Sun X,Xie Q

更新日期：2019-02-19 00:00:00

abstract：:Background and Purpose: Acute intracerebral hemorrhage (ICH) requires rapid decision making toward neurosurgery or conservative neurological stroke unit treatment. In a previous study, we found overestimation of clinical symptoms when clinicians rely mainly on cerebral computed tomography (cCT) analysis. The current s...

journal_title：Frontiers in neurology

authors： Wagner A,Schebesch KM,Isenmann S,Steinbrecher A,Kapapa T,Zeman F,Baldaranov D,Grauer O,Backhaus R,Linker RA,Schlachetzki F

更新日期：2019-09-26 00:00:00

abstract：OBJECTIVE:Our aim was to identify the role of the investigators' knowledge of the patient's history of vestibular symptoms (PVH) in the clinical evaluation of the bedside head-impulse test (bHIT). We hypothesized that this knowledge will reduce uncertainty and improve bHIT accuracy when compared to quantitative analysi...

journal_title：Frontiers in neurology

authors： Helmchen C,Knauss J,Trillenberg P,Frendl A,Sprenger A

更新日期：2017-02-20 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:The therapy of focal epilepsy remains unsatisfactory for as many as 25% of patients. The photolysis of caged-γ-aminobutyric acid (caged-GABA) represents a novel and alternative option for the treatment of intractable epilepsy. Our previous experimental results have demonstrated that the use of blue light produced by l...

journal_title：Frontiers in neurology

authors： Wang D,Yu Z,Yan J,Xue F,Ren G,Jiang C,Wang W,Piao Y,Yang X

更新日期：2017-05-18 00:00:00

abstract：:We present a case of a 43-year-old woman with a history of headaches and blurry vision. Ophthalmologic examination identified papilledema. MR imaging demonstrated a right parietal region mass with patchy areas of contrast enhancement and focal calcifications. Intraoperative examination and exploration revealed an extr...

journal_title：Frontiers in neurology

authors： Ballester LY,Dunbar E,Guha-Thakurta N,Henson JW,Chandler H,Watkins J,Fuller GN

更新日期：2018-08-27 00:00:00

abstract：:Magnetic resonance elastography (MRE) is a non-invasive imaging technique, using the propagation of mechanical waves as a probe to palpate biological tissues. It consists in three main steps: production of shear waves within the tissue; encoding subsequent tissue displacement in magnetic resonance images; and extracti...

journal_title：Frontiers in neurology

authors： Bigot M,Chauveau F,Beuf O,Lambert SA

更新日期：2018-11-27 00:00:00

abstract：:Migraine is a chronic disease characterized by unilateral, pulsating, and often moderate-to-severe recurrent episodes of headache with nausea and vomiting. It affects approximately 15% of the general population, yet the underlying pathophysiological mechanisms are not fully understood. Optical coherence tomography (OC...

journal_title：Frontiers in neurology

authors： Ascaso FJ,Marco S,Mateo J,Martínez M,Esteban O,Grzybowski A

更新日期：2017-12-13 00:00:00

abstract：:Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular end-organ disease, and it is one of the first causes of access to the emergency room. The moment of migration of the otoconial debris in a semicircular canal does not necessarily coincide with the moment of detachment of the debris th...

journal_title：Frontiers in neurology

authors： Gufoni M,Vianini M,Casani AP

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:A possible link between 3D movies and headache (HA) has never been a target of specific and systematic investigations. The aim of this study was to investigate the relationship between 3D cinema and HA and to evaluate possible risk factors of developing HA during or after watching a 3D movie. METHODS:This w...

journal_title：Frontiers in neurology

authors： Braschinsky M,Raidvee A,Sabre L,Zmachinskaja N,Zukovskaja O,Karask A,Saar B,Rakitin A

更新日期：2016-03-23 00:00:00

abstract：:Background: Trigeminal neuralgia (TN) is a recognized pain condition the treatment of which can be very challenging. Various surgical interventions can be applied in cases of therapy-resistance to drug treatments. The central lateral thalamotomy (CLT) against neurogenic (or neuropathic) pain is based on multiarchitect...

journal_title：Frontiers in neurology

authors： Gallay MN,Moser D,Jeanmonod D

更新日期：2020-04-17 00:00:00

abstract：:Periodontitis is an oral inflammatory disease and may contribute to low-grade systemic inflammation. Based on the contribution of periodontitis to systemic inflammation and the potential role of systemic inflammation in neuroinflammation, many epidemiological studies have investigated a possible association between pe...

journal_title：Frontiers in neurology

authors： Nascimento PC,Castro MML,Magno MB,Almeida APCPSC,Fagundes NCF,Maia LC,Lima RR

更新日期：2019-04-24 00:00:00

abstract：:Tau plays an important pathological role in a group of neurodegenerative diseases called tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic encephalopathy and corticobasal degeneration. In each disease, tau self-assembles abnormally to form filaments that deposit in the brain. Tau is a nativ...

journal_title：Frontiers in neurology

authors： Oakley SS,Maina MB,Marshall KE,Al-Hilaly YK,Harrington CR,Wischik CM,Serpell LC

更新日期：2020-11-12 00:00:00

abstract：:Neurocysticercosis (NC) is the most common parasitic infection of the central nervous system (CNS). Several studies have reported an association between NC and mesial temporal lobe epilepsy (MTLE). We intended to evaluate the frequency of hippocampal atrophy (HA), clinical evolution and imaging findings in patients wi...

journal_title：Frontiers in neurology

authors： Jama-António JMC,Yasuda CL,Cendes F

更新日期：2019-04-30 00:00:00

abstract：:New-onset refractory status epilepticus (NORSE) is a rare but challenging condition occurring in a previously healthy patient, often with no identifiable cause. We describe the electro-clinical features and outcomes in a group of patients with NORSE who all demonstrated a typical magnetic resonance imaging (MRI) sign ...

journal_title：Frontiers in neurology

authors： Meletti S,Giovannini G,d'Orsi G,Toran L,Monti G,Guha R,Kiryttopoulos A,Pascarella MG,Martino T,Alexopoulos H,Spilioti M,Slonkova J

更新日期：2017-03-27 00:00:00

abstract：:Objective: To investigate an MRI-based etiological classification for acute isolated pontine infarcts and to assess differences in vascular risk factors, clinical characteristics and WMH burden among the etiological subtypes. Methods: All participants from SMART cohort with DWI-proven acute isolated pontine infarcts (...

journal_title：Frontiers in neurology

authors： Zhou L,Yao M,Peng B,Zhu Y,Ni J,Cui L

更新日期：2018-10-09 00:00:00

abstract：:Background: While acute stress and pain are part of our inherent survival mechanisms, persistent stress and pain can negatively impact health and well-being. This may also lead to poor sleep and thus a lack of recovery. This study investigated the influence of stress and musculoskeletal pain on sleep quality. Methods:...

journal_title：Frontiers in neurology

authors： Vinstrup J,Jakobsen MD,Calatayud J,Jay K,Andersen LL

更新日期：2018-11-21 00:00:00

abstract：:Traumatic brain injury is the leading cause of death in children. Children with severe TBI are in need of neurointensive care where the goal is to prevent secondary brain injury by avoiding secondary insults. Monitoring of cerebral blood flow (CBF) and autoregulation in the injured brain is crucial. However, there are...

journal_title：Frontiers in neurology

authors： Rostami E,Nilsson P,Enblad P

更新日期：2020-04-16 00:00:00

abstract：:Background: Recent developments in mobile technology have enabled the investigation of human movements and mobility under natural conditions, i.e., in the home environment. Iron accumulation in the basal ganglia is deleterious in Parkinson's disease (i.e., iron accumulation with lower striatal level of dopamine). The ...

journal_title：Frontiers in neurology

authors： Hopfner F,Hobert MA,Maetzler C,Hansen C,Pham MH,Moreau C,Berg D,Devos D,Maetzler W,Fair-Park II study group.

更新日期：2019-08-08 00:00:00

abstract：:Genetic findings of the past years have provided ample evidence for a substantial etiologic heterogeneity of dystonic syndromes. While an increasing number of genes are being identified for Mendelian forms of isolated and combined dystonias using classical genetic mapping and whole-exome sequencing techniques, their p...

journal_title：Frontiers in neurology

authors： Verbeek DS,Gasser T

更新日期：2017-01-16 00:00:00

abstract：:The vestibular system plays a crucial role in the multisensory control of balance. When vestibular function is lost, essential tasks such as postural control, gaze stabilization, and spatial orientation are limited and the quality of life of patients is significantly impaired. Currently, there is no effective treatmen...

journal_title：Frontiers in neurology

authors： Perez Fornos A,Guinand N,van de Berg R,Stokroos R,Micera S,Kingma H,Pelizzone M,Guyot JP

更新日期：2014-04-29 00:00:00