Mobility Deficits Assessed With Mobile Technology: What Can We Learn From Brain Iron-Altered Animal Models?

abstract：:Background: Ischemic cerebral infarction is a severe clinical condition that can cause serious mortality. Artesunate, an anti-malarial drug that is widely used in cancer treatment, is known to facilitate accelerated cell apoptosis. The aim of this study is to explore the possible neuroprotective effects of artesunate ...

journal_title：Frontiers in neurology

authors： Shao M,Shen Y,Sun H,Meng D,Huo W,Qi X

更新日期：2018-08-17 00:00:00

abstract：:When the diagnosis of myasthenia gravis (MG) has been secured, the aim of management should be prompt symptom control and the induction of remission or minimal manifestations. Symptom control, with acetylcholinesterase inhibitors such as pyridostigmine, is commonly employed. This may be sufficient in mild disease. The...

journal_title：Frontiers in neurology

authors： Farrugia ME,Goodfellow JA

更新日期：2020-07-07 00:00:00

abstract：:Background: Phosphatidylinositol binding clathrin assembly protein (PICALM) rs541458 C allele has been identified and validated to be associated with a reduction of Alzheimer's disease (AD) risk. Nevertheless, the exact mechanisms through which the variant exert its disease-relevant association remain to be elucidated...

journal_title：Frontiers in neurology

authors： Zhuang L,Liu X,Shi Y,Liu X,Luo B

更新日期：2019-05-08 00:00:00

abstract：:We sought to investigate (1) the characteristics of epileptiform discharge (ED) duration and interdischarge interval (IDI) and (2) the influence of vigilance state on the ED duration and IDI in genetic generalized epilepsy (GGE). In a cohort of patients diagnosed with GGE, 24-h ambulatory EEG recordings were performed...

journal_title：Frontiers in neurology

authors： Seneviratne U,Boston RC,Cook MJ,D'Souza WJ

更新日期：2018-02-19 00:00:00

abstract：:Surface electromyography (sEMG) is a widely used technology in rehabilitation research and provides quantifiable information on the myoelectric output of a muscle. In this perspective, we discuss the barriers which have restricted the wide-spread use of sEMG in clinical rehabilitation of individuals with spinal cord i...

journal_title：Frontiers in neurology

authors： Pilkar R,Momeni K,Ramanujam A,Ravi M,Garbarini E,Forrest GF

更新日期：2020-12-18 00:00:00

abstract：:Introduction: Safe driving requires integration of higher-order cognitive and motor functions, which are commonly compromised in patients with antibody-mediated encephalitis (AME) associated with N-methyl-D-aspartate receptors or leucine-rich glioma-inactivated 1 autoantibodies. How these deficits influence the return...

journal_title：Frontiers in neurology

authors： Day GS,Babulal GM,Rajasekar G,Stout S,Roe CM

更新日期：2020-07-28 00:00:00

abstract：:Surface electromyography (sEMG) is a non-invasive method, which may be used in France by health practitioners without medical degree, such as physiotherapists, who are taught in Institutes of physiotherapy. However, very few hours are devoted to sEMG teaching in physiotherapist educational programs, especially in a fo...

journal_title：Frontiers in neurology

authors： Portero P,Dogadov AA,Servière C,Quaine F

更新日期：2020-12-03 00:00:00

abstract：:Alzheimer's disease (AD) is the most prevalent form of late-onset dementia. AD affects the health of millions of people in the United States and worldwide. Currently, there are no approved therapies that can halt or reverse the clinical progression of AD. Traditionally, AD is characterized first by the appearance of a...

journal_title：Frontiers in neurology

authors： Hanslik KL,Ulland TK

更新日期：2020-09-18 00:00:00

abstract：:Background: Cognitive impairments in temporal lobe epilepsy (TLE) patients has been described as a chronically progressive feature of the disease. However, how severe recurrent seizures modify neuronal circuits in the human brain and subsequently degrade cognitive function, remains largely unknown. Here, we aimed to i...

journal_title：Frontiers in neurology

authors： Qin L,Jiang W,Zheng J,Zhou X,Zhang Z,Liu J

更新日期：2020-07-21 00:00:00

abstract：:Objectives: To report two novel DNA2 gene mutations causing early onset myopathy with cardiac involvement and late onset mitochondriopathy with rhabdomyolysis. Methods: We performed detailed clinical, muscle histopathology and molecular studies including mitochondrial gene NGS analysis in two patients (Patient 1 and 2...

journal_title：Frontiers in neurology

authors： González-Del Angel A,Bisciglia M,Vargas-Cañas S,Fernandez-Valverde F,Kazakova E,Escobar RE,Romero NB,Jardel C,Rucheton B,Stojkovic T,Malfatti E

更新日期：2019-10-04 00:00:00

abstract：:Stroke is a leading cause of death and disability, and recombinant tissue plasminogen activator (rtPA) can significantly reduce the long-term impact of acute ischemic stroke (AIS) if given within 3 h of symptom onset. South Carolina is located in the "stroke belt" and has a high rate of stroke and stroke mortality. Ma...

journal_title：Frontiers in neurology

authors： Kazley AS,Wilkerson RC,Jauch E,Adams RJ

更新日期：2012-03-21 00:00:00

abstract：:We describe the case of one patient with pure sporadic hemiplegic migraine (SHM) with a novel ATP1A2 gene variant and a large patent foramen ovale (PFO) with atrial septal aneurysm. In hemiplegic migraine (HM), the relationship between incomplete penetrance, environmental triggers, and phenotypic expression is underde...

journal_title：Frontiers in neurology

authors： Perrotta A,Gambardella S,Ambrosini A,Anastasio MG,Albano V,Fornai F,Pierelli F

更新日期：2018-05-17 00:00:00

abstract：:Introduction: Myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG)-related disease was initially described as a subtype of neuromyelitis optica spectrum disorder (NMOSD) with antibodies against MOG. However, it has recently been described as a separate disease entity with clinical and radiological features t...

journal_title：Frontiers in neurology

authors： Alshamrani F,Alnajashi H,Shosha E,Casserly C,Morrow SA

更新日期：2020-02-26 00:00:00

abstract：:Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal stenosis and the hemodynamic significance of middle cerebral artery (MCA) steno...

journal_title：Frontiers in neurology

authors： Fang H,Leng X,Pu Y,Zou X,Pan Y,Song B,Soo YOY,Leung TWH,Wang C,Zhao X,Wang Y,Wang Y,Wong KS,Liu L,Xu Y,CICAS Study Group.

更新日期：2020-04-15 00:00:00

abstract：:During neurorehabilitation, clinical measurements are widely adopted to evaluate behavioral improvements after treatment. However, it is not able to identify or monitor the change of central nervous system (CNS) of each individual patient. Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely u...

journal_title：Frontiers in neurology

authors： Ge Y,Pan Y,Wu Q,Dou W

更新日期：2019-11-01 00:00:00

abstract：:Background: Spinal and Bulbar Muscular Atrophy (SBMA) is caused by the extension of the polyglutamine tract within the androgen receptor (AR) gene, and results in a multisystem presentation, including the degeneration of lower motor neurons. The androgen receptor (AR) is known to modulate the expression of endogenous ...

journal_title：Frontiers in neurology

authors： Rex C,Nadeau MJ,Douville R,Schellenberg K

更新日期：2019-09-04 00:00:00

abstract：:The Boston Carpal Tunnel Questionnaire (BCTQ) is a scale that has been developed specifically for carpal tunnel syndrome (CTS). It consists of the Functional Status Scale (FSS) and the Symptom Severity Scale (SSS). It is the most widely used patient reported outcome measure in CTS and has been validated in many langua...

journal_title：Frontiers in neurology

authors： De Kleermaeker FGCM,Levels M,Verhagen WIM,Meulstee J

更新日期：2019-11-07 00:00:00

abstract：:This study reports the case of an acoustic shock injury (ASI), which did not result in a significant hearing loss, but was followed by manifold chronic symptoms both within (tinnitus, otalgia, tingling in the ear, tension in the ear, and red tympanum) and outside the ears (blocked nose, pain in the neck/temporal regio...

journal_title：Frontiers in neurology

authors： Londero A,Charpentier N,Ponsot D,Fournier P,Pezard L,Noreña AJ

更新日期：2017-08-16 00:00:00

abstract：:New-onset refractory status epilepticus (NORSE) is a rare but challenging condition occurring in a previously healthy patient, often with no identifiable cause. We describe the electro-clinical features and outcomes in a group of patients with NORSE who all demonstrated a typical magnetic resonance imaging (MRI) sign ...

journal_title：Frontiers in neurology

authors： Meletti S,Giovannini G,d'Orsi G,Toran L,Monti G,Guha R,Kiryttopoulos A,Pascarella MG,Martino T,Alexopoulos H,Spilioti M,Slonkova J

更新日期：2017-03-27 00:00:00

abstract：INTRODUCTION:Options currently available to individuals with upper limb loss range from prosthetic hands that can perform many movements, but require more cognitive effort to control, to simpler terminal devices with limited functional abilities. We attempted to address this issue by designing a myoelectric control sys...

journal_title：Frontiers in neurology

authors： Gailey A,Artemiadis P,Santello M

更新日期：2017-02-01 00:00:00

abstract：:Introduction: The headache phase of migraine could in selected cases potentially be treated by surgical decompression of one or more "trigger sites," located at frontal, temporal, nasal, and occipital sites. This systematic review with subsequent meta-analysis aims at critically evaluating the currently available evid...

journal_title：Frontiers in neurology

authors： Vincent AJPE,van Hoogstraten WS,Maassen Van Den Brink A,van Rosmalen J,Bouwen BLJ

更新日期：2019-02-14 00:00:00

abstract：:COVID-19 has rapidly become a pandemic emergency, distressing health systems in each affected country. COVID-19 determines the need for healthcare in a large number of people in an extremely short time and, like a tsunami wave, overruns emergency, infectious diseases, and pneumology departments as well as intensive ca...

journal_title：Frontiers in neurology

authors： Bartolo M,Intiso D,Lentino C,Sandrini G,Paolucci S,Zampolini M,Board of the Italian Society of Neurological Rehabilitation (SIRN).

更新日期：2020-04-30 00:00:00

abstract：:With the advent of susceptibility-weighted imaging (SWI), the ability to identify cerebral microbleeds (CMBs) associated with mild traumatic brain injury (mTBI) has become increasingly commonplace. Nevertheless, the clinical significance of post-traumatic CMBs remains controversial partly because it is unclear whether...

journal_title：Frontiers in neurology

authors： Rostowsky KA,Maher AS,Irimia A

更新日期：2018-11-13 00:00:00

abstract：:Manual dexterity measures can be useful for early detection of age-related functional decline and for prediction of cognitive decline. However, what aspects of sensorimotor function to assess remains unclear. Manual dexterity markers should be able to separate impairments related to cognitive decline from those relate...

journal_title：Frontiers in neurology

authors： Carment L,Abdellatif A,Lafuente-Lafuente C,Pariel S,Maier MA,Belmin J,Lindberg PG

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND AND PURPOSE:Cardiac myxoma is a rare etiology of stroke. Both cerebral microbleeds and cardiac myxoma may increase the risk of intracerebral hemorrhage after intravenous (IV) thrombolysis. However, data are still limited. We report a case of multiple cerebral microbleeds treated with IV thrombolysis with lat...

journal_title：Frontiers in neurology

authors： Chutinet A,Roongpiboonsopit D,Suwanwela NC

更新日期：2014-12-01 00:00:00

abstract：:X-linked adrenoleukodystrophy (X-ALD) is a rare neurological disorder with a highly complex clinical presentation. Adrenal function, spinal cord, peripheral nerves, and cerebral white matter are commonly affected in adult-onset male patients. Here, we report a family with unusual presentation of X-ALD. The 19-year-old...

journal_title：Frontiers in neurology

authors： Chen Y,Zhang J,Wang J,Wang K

更新日期：2018-04-23 00:00:00

abstract：BACKGROUND:Spinocerebellar ataxia type 2 (SCA2) is an inherited and still incurable neurodegenerative disorder. Evidence suggests that pro-oxidant agents as well as factors involved in antioxidant cellular defenses are part of SCA2 physiopathology. AIM:To assess the influence of superoxide dismutase (SOD3) and catalas...

journal_title：Frontiers in neurology

authors： Almaguer-Gotay D,Almaguer-Mederos LE,Aguilera-Rodríguez R,Rodríguez-Labrada R,Cuello-Almarales D,Estupiñán-Domínguez A,Velázquez-Pérez LC,González-Zaldívar Y,Vázquez-Mojena Y

更新日期：2017-06-13 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2019.00129.]. ...

journal_title：Frontiers in neurology

authors： Frontiers Production Office.

更新日期：2019-03-27 00:00:00

abstract：:Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic transformation. While significant advances have been made over the past two decades with regard to emergent treatment of AIS, many of the therapeutic options are limited by an increased risk of hemorrhage. Here, we sought to review...

journal_title：Frontiers in neurology

authors： Sussman ES,Connolly ES Jr

更新日期：2013-06-10 00:00:00