Cerebral Blood Flow Measurement in Healthy Children and Children Suffering Severe Traumatic Brain Injury-What Do We Know?

abstract：:Background and objective: The trajectories of long-term and domain-specific cognitive alterations over a decade after stroke are largely unknown. This study aims to investigate the dynamic alterations of domain-specific cognitive performance among young stroke survivors over 10 years after their first stroke. Methods:...

journal_title：Frontiers in neurology

authors： Elgh E,Hu X

更新日期：2019-02-12 00:00:00

abstract：:Background: The causal relationship between serum lipid levels and the risk of Parkinson's disease (PD) remains largely uncertain. We summarized the existing controversial evidence on this topic. Methods: We searched the electronic databases for observational studies from January 1988 to March 2020. We applied random-...

journal_title：Frontiers in neurology

authors： Jiang Z,Xu X,Gu X,Ou R,Luo X,Shang H,Song W

更新日期：2020-06-26 00:00:00

abstract：:Intensive glycemic control has not shown consistent findings in stroke prevention for diabetes patients, particularly for those with microvascular complications. This case-control study evaluates the risks of stroke in Asian diabetic population with microvascular complications. From the insurance claims of Taiwan, we ...

journal_title：Frontiers in neurology

authors： Lo SF,Chen WL,Muo CH,Chen PC,Chen SY,Kuo CL,Sung FC

更新日期：2018-08-29 00:00:00

abstract：:Tumors or chronic inflammatory lesions of the occipital condyle may cause occipital pain associated with an ipsilateral hypoglossal nerve injury (occipital condyle syndrome). We describe a young woman with recurrent otitis media and occipital condyle syndrome associated with a limited form of Wegener's disease. ...

journal_title：Frontiers in neurology

authors： Hornik A,Rodriguez-Porcel F,Ersahin CH,Kadanoff R,Biller J

更新日期：2012-04-12 00:00:00

abstract：:Background: Given the lethal severity of amyotrophic lateral sclerosis (ALS), the aim of this study was to illuminate the coherence of depression and death anxiety in both ALS patients and caregivers and in how far patients and caregivers are influenced by the mindset of their respective counterpart. Methods: 30 coupl...

journal_title：Frontiers in neurology

authors： Grabler MR,Weyen U,Juckel G,Tegenthoff M,Mavrogiorgou-Juckel P

更新日期：2018-12-03 00:00:00

abstract：:Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this fact is well known, there has been a remarkable lack of progress in determining the pathophysiological mechanisms behind fatigue and the establishment of effective treatments. The main barrier has been the lack of a unified...

journal_title：Frontiers in neurology

authors： Rudroff T,Kindred JH,Ketelhut NB

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Hemiparesis after stroke typically results in a reduced walking speed, an asymmetrical gait pattern and a reduced ability to make gait adjustments. The purpose of this pilot study was to investigate the feasibility and preliminary efficacy of home-based training involving auditory cueing of stepping in place...

journal_title：Frontiers in neurology

authors： Wright RL,Brownless SB,Pratt D,Sackley CM,Wing AM

更新日期：2017-08-22 00:00:00

abstract：:Ornithine transcarbamylase deficiency (OTCD) is the most common form of urea cycle disorder characterized by the presence of hyperammonemia (HA). In patients with OTCD, HA is known to cause impairments in domains of executive function and working memory. Monitoring OTCD progression and investigating neurocognitive bio...

journal_title：Frontiers in neurology

authors： Anderson AA,Gropman A,Le Mons C,Stratakis CA,Gandjbakhche AH

更新日期：2020-08-14 00:00:00

abstract：:Objective: To identify reproducible sub-classes of traumatic brain injury (TBI) that correlate with patient outcomes. Methods: Two TBI datasets from the Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System were utilized, Transforming Research and Clinical Knowledge in Traumatic Brain Injury ...

journal_title：Frontiers in neurology

authors： Si B,Dumkrieger G,Wu T,Zafonte R,Dodick DW,Schwedt TJ,Li J

更新日期：2018-08-13 00:00:00

abstract：:In the present study, we investigated the genetic variation in a family with acute encephalopathy and retinitis pigmentosa. Nine of 25 people in this family underwent genetic testing. Three family members, namely, the proband and the proband's two sisters, showed symptoms resembling those of meningoencephalitis and si...

journal_title：Frontiers in neurology

authors： You C,Zeng W,Deng L,Lei Z,Gao X,Zhang VW,Wang Y

更新日期：2020-05-05 00:00:00

abstract：:Background: Discharge planning of stroke patients during inpatient neurorehabilitation is often difficult since it depends both on the patient's ability to perform activities of daily living (ADL) and the social context. The aim of this study was to define ADL cut-off scores using the Lucerne ICF-based multidisciplina...

journal_title：Frontiers in neurology

authors： Ottiger B,Lehnick D,Pflugshaupt T,Vanbellingen T,Nyffeler T

更新日期：2020-11-25 00:00:00

abstract：:Background: Cognitive impairments in temporal lobe epilepsy (TLE) patients has been described as a chronically progressive feature of the disease. However, how severe recurrent seizures modify neuronal circuits in the human brain and subsequently degrade cognitive function, remains largely unknown. Here, we aimed to i...

journal_title：Frontiers in neurology

authors： Qin L,Jiang W,Zheng J,Zhou X,Zhang Z,Liu J

更新日期：2020-07-21 00:00:00

abstract：:The most frequent neurodegenerative diseases (NDs) are Alzheimer's disease (AD), Parkinson's disease (PD), and frontotemporal lobar degeneration associated with protein TDP-43 (FTLD-TDP). Neuropathologically, NDs are characterized by abnormal intracellular and extra-cellular protein deposits and by disease-specific ne...

journal_title：Frontiers in neurology

authors： Grinberg LT,Rueb U,Heinsen H

更新日期：2011-07-11 00:00:00

abstract：:Although ~50% of patients with Parkinson's disease (PD) experience depression, treatment for this important and debilitating comorbidity is relatively understudied. Deep brain stimulation (DBS) has been increasingly utilized for the management of tremors in progressive PD. Several preliminary studies have shown the po...

journal_title：Frontiers in neurology

authors： Gökbayrak NS,Piryatinsky I,Gavett RA,Ahmed OJ

更新日期：2014-08-11 00:00:00

abstract：:Hemiconvulsion-hemiplegia-epilepsy syndrome (HHE) is a rare outcome of prolonged hemiconvulsion that is followed by diffuse unilateral hemispheric edema, hemiplegia, and ultimately hemiatrophy of the affected hemisphere and epilepsy. Here, we describe the case of a 3-year-old male with a 1;3 translocation leading to a...

journal_title：Frontiers in neurology

authors： Robinson JE,Wolfe SM,Kaiser-Rogers K,Greenwood RS

更新日期：2016-05-04 00:00:00

abstract：:Background: Strokes have a huge impact on patients' quality of life. Although there are potentially effective secondary preventions and treatment options for stroke patients, adherence is mostly low. Low disease and treatment-related knowledge and, consequently, a lack of informed decision-making in stroke patients ma...

journal_title：Frontiers in neurology

authors： Alegiani AC,Rahn AC,Steckelberg A,Thomalla G,Heesen C,Köpke S

更新日期：2020-12-07 00:00:00

abstract：:Adolescents with traumatic brain injury (TBI) typically demonstrate good recovery of previously acquired skills. However, higher-order and later emergent cognitive functions are often impaired and linked to poor outcomes in academic and social/behavioral domains. Few control trials exist that test cognitive treatment ...

journal_title：Frontiers in neurology

authors： Cook LG,Chapman SB,Elliott AC,Evenson NN,Vinton K

更新日期：2014-06-11 00:00:00

abstract：:Background: Studies have investigated the lipid profile in amyotrophic lateral sclerosis (ALS), including the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and higher low-density lipoprotein (LDL), and the associations with mortality of ALS, but the results were inconsistent. The...

journal_title：Frontiers in neurology

authors： Liu J,Luo X,Chen X,Shang H

更新日期：2020-10-15 00:00:00

abstract：:Moderate-severe traumatic brain injury (TBI) may result in difficulty with emotion recognition, which has negative implications for social functioning. As aspects of social cognition have been linked to resting-state functional connectivity (RSFC) in the default mode network (DMN), we sought to determine whether DMN c...

journal_title：Frontiers in neurology

authors： Lancaster K,Venkatesan UM,Lengenfelder J,Genova HM

更新日期：2019-08-09 00:00:00

abstract：:Background and Purpose: The effect of uric acid (UA) levels on severity and prognosis of spontaneous intracerebral hemorrhage (ICH) remains controversial. We aimed to explore the association of admission UA levels with stroke severity and outcomes in ICH patients. Materials and Methods: The patients enrolled in this s...

journal_title：Frontiers in neurology

authors： Liu X,Cao Z,Gu H,Yang K,Ji R,Li Z,Zhao X,Wang Y

更新日期：2020-12-03 00:00:00

abstract：Background:Cerebral microcirculation after severe head injury is heterogeneous and temporally variable. Microcirculation is dependent upon the severity of injury, and it is unclear how histology relates to cerebral regional blood flow. Objective:This study assesses the changes of cerebral microcirculation blood flow o...

journal_title：Frontiers in neurology

authors： Bellapart J,Cuthbertson K,Dunster K,Diab S,Platts DG,Raffel OC,Gabrielian L,Barnett A,Paratz J,Boots R,Fraser JF

更新日期：2018-05-07 00:00:00

abstract：:Objective: This study aimed to screen gene mutations in Chinese patients with benign essential blepharospasm (BEB) to understand its etiology. Methods: Twenty BEB patients diagnosed by clinical manifestations between April 2015 and October 2015 were enrolled. All the cases were investigated by questionnaires about gen...

journal_title：Frontiers in neurology

authors： Dong H,Luo Y,Fan S,Yin B,Weng C,Peng B

更新日期：2020-01-23 00:00:00

abstract：:Objective: Lipohyalinosis or atherosclerosis might be responsible for single subcortical infarctions (SSIs); however, ways of differentiating between the two clinically remain uncertain. We aimed to investigate whether consecutive slides on axial view or transversal diameter is more effective to differentiate mechanis...

journal_title：Frontiers in neurology

authors： Cao Y,Zhang M,Zhou L,Yao M,Peng B,Zhu Y,Ni J,Cui L

更新日期：2019-04-09 00:00:00

abstract：:Gross motor impairments are common after stroke, but efficient and motivating therapies for these impairments are scarce. We present an innovative musical sonification therapy, especially designed to retrain patients' gross motor functions. Sonification should motivate patients and provide additional sensory input inf...

journal_title：Frontiers in neurology

authors： Scholz DS,Rohde S,Nikmaram N,Brückner HP,Großbach M,Rollnik JD,Altenmüller EO

更新日期：2016-06-30 00:00:00

abstract：:Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions. Studies on intracranial large arteries in CADASIL are not common. We aim to evaluate intracranial l...

journal_title：Frontiers in neurology

authors： Zhang C,Li W,Li S,Niu S,Wang X,Yu X,Zhang Z

更新日期：2020-08-18 00:00:00

abstract：:Glaucoma is a multifactorial syndrome in which the development of pro-apoptotic signals are the causes for retinal ganglion cell (RGC) loss. Most of the research progress in the glaucoma field have been based on experimentally inducible glaucoma animal models, which provided results about RGC loss after either the cra...

journal_title：Frontiers in neurology

authors： Tirendi S,Saccà SC,Vernazza S,Traverso C,Bassi AM,Izzotti A

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:Dizziness is a common reason patients present to doctors, but effective diagnostic tests and treatments for dizziness are underused. The internet is a way to disseminate medical information and is emerging as an intervention platform. The objective of this study was to describe internet searches for dizziness...

journal_title：Frontiers in neurology

authors： Kerber KA,Skolarus LE,Callaghan BC,Zheng K,Zhang Y,An LC,Burke JF

更新日期：2014-04-16 00:00:00

abstract：:Tadpole pupil is a rare phenomenon in which segmental spasm of the iris dilator muscle results in a tadpole-shaped pupil. The pupillary distortion is usually unilateral, lasts several minutes, and can recur in clusters. Any segment of the iris can be affected; thus, for some patients, a different-shaped tadpole pupil ...

journal_title：Frontiers in neurology

authors： Udry M,Kardon RH,Sadun F,Kawasaki A

更新日期：2019-08-19 00:00:00

abstract：:Hearing and balance impairment are the most frequently reported features of infratentorial (classical) superficial siderosis (iSS). There are few comprehensive descriptions of audiovestibular function in iSS and therefore limited understanding of the affected segment(s) of the audiovestibular pathway. In addition, mon...

journal_title：Frontiers in neurology

authors： Kharytaniuk N,Cowley P,Werring DJ,Bamiou DE

更新日期：2021-01-14 00:00:00

abstract：OBJECTIVE:Morphological changes of recent small subcortical infarcts are not well defined. The purpose of the present study was to describe the MRI characteristics of the evolution for this stroke subtype. METHODS:We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subco...

journal_title：Frontiers in neurology

authors： Okazaki S,Hornberger E,Griebe M,Gass A,Hennerici MG,Szabo K

更新日期：2015-05-26 00:00:00