Magnetic Resonance Elastography of Rodent Brain.

abstract：:Different subtypes of Alzheimer's disease (AD) with characteristic distributions of neurofibrillary tangles and corresponding brain atrophy patterns have been identified using structural magnetic resonance imaging (MRI). However, the underlying biological mechanisms that determine this differential expression of neuro...

journal_title：Frontiers in neurology

authors： Ferreira D,Pereira JB,Volpe G,Westman E

更新日期：2019-05-28 00:00:00

abstract：:Cognitive impairment is prevalent and disabling in multiple sclerosis (MS) and is severely impacting quality of life (QoL). Aside its routine assessment in clinical care, it should more often be implemented as endpoint/outcome measure in clinical trials. However, a fundamental aspect-often neglected in clinical practi...

journal_title：Frontiers in neurology

authors： Beste C,Ziemssen T

更新日期：2020-08-28 00:00:00

abstract：:The developmental vulnerability of different classes of axonal pathways in preterm white matter is not known. We propose that laminar compartments of the developing cerebral wall serve as spatial framework for axonal growth and evaluate potential of anatomical landmarks for understanding reorganization of the cerebral...

journal_title：Frontiers in neurology

authors： Kostović I,Kostović-Srzentić M,Benjak V,Jovanov-Milošević N,Radoš M

更新日期：2014-07-29 00:00:00

abstract：:The most frequent neurodegenerative diseases (NDs) are Alzheimer's disease (AD), Parkinson's disease (PD), and frontotemporal lobar degeneration associated with protein TDP-43 (FTLD-TDP). Neuropathologically, NDs are characterized by abnormal intracellular and extra-cellular protein deposits and by disease-specific ne...

journal_title：Frontiers in neurology

authors： Grinberg LT,Rueb U,Heinsen H

更新日期：2011-07-11 00:00:00

abstract：Background:Temporal lobe epilepsy (TLE) is one of the most drug-resistant types of epilepsy with about 80% of TLE patients falling into this category. Increasing evidence suggests that neuroinflammation, which has a critical role in the epileptogenesis of TLE, is associated with microglial activation. Therefore, agents...

journal_title：Frontiers in neurology

authors： Liu HJ,Lai X,Xu Y,Miao JK,Li C,Liu JY,Hua YY,Ma Q,Chen Q

更新日期：2017-12-14 00:00:00

abstract：:Functional magnetic resonance imaging studies suggest that different subcortico-cortical circuits control different aspects of Parkinsonian rest tremor. The basal ganglia were proposed to drive tremor onset, and the cerebellum was suggested to be responsible for tremor maintenance ("dimmer-switch" hypothesis). Althoug...

journal_title：Frontiers in neurology

authors： Hirschmann J,Abbasi O,Storzer L,Butz M,Hartmann CJ,Wojtecki L,Schnitzler A

更新日期：2019-03-07 00:00:00

abstract：:Inconclusive results have been reported in studies investigating the association between the brain-derived neurotrophic factor (BDNF) rs6265 polymorphism and migraine. In the present study, we conducted a systematic review and meta-analysis on the published data in order to quantitatively estimate the relationship bet...

journal_title：Frontiers in neurology

authors： Terrazzino S,Cargnin S,Viana M,Sances G,Tassorelli C

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to systematically review the efficacy and tolerability of gabapentin in the treatment of sleep disturbance in patients with medical illness. METHODS:PubMed was searched for randomized, double-blinded, placebo-controlled trials that reported sleep changes during gabapent...

journal_title：Frontiers in neurology

authors： Liu GJ,Karim MR,Xu LL,Wang SL,Yang C,Ding L,Wang YF

更新日期：2017-07-14 00:00:00

abstract：:Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

journal_title：Frontiers in neurology

authors： Lu H,Wu PF,Li RZ,Zhang W,Huang GX

更新日期：2020-10-07 00:00:00

abstract：:Guillain-Barré syndrome (GBS) is mainly associated with preceding exposure to an infectious agent, although the precise pathogenic mechanisms and causes remain unknown. Increasing evidence indicates an association between trauma-related factors and GBS. Here, we performed a systematic review, summarized the current sc...

journal_title：Frontiers in neurology

authors： Huang C,Zhang Y,Deng S,Ren Y,Lu W

更新日期：2020-11-06 00:00:00

abstract：:Background: Studies have investigated the lipid profile in amyotrophic lateral sclerosis (ALS), including the levels of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), and higher low-density lipoprotein (LDL), and the associations with mortality of ALS, but the results were inconsistent. The...

journal_title：Frontiers in neurology

authors： Liu J,Luo X,Chen X,Shang H

更新日期：2020-10-15 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00

abstract：INTRODUCTION:We sought to determine whether compliance with scheduled nimodipine in subarachnoid hemorrhage patients impacted patient outcomes, with the intent of guiding future nimodipine management in patients who experience nimodipine-induced hypotension. METHODS:We performed a retrospective analysis of 118 consecu...

journal_title：Frontiers in neurology

authors： Wessell A,Kole MJ,Badjatia N,Parikh G,Albrecht JS,Schreibman DL,Simard JM

更新日期：2017-06-09 00:00:00

abstract：BACKGROUND:Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied. METHODS:We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range ...

journal_title：Frontiers in neurology

authors： Shalaby S,Indes J,Keung B,Gottschalk CH,Machado D,Patel A,Robakis D,Louis ED

更新日期：2016-04-22 00:00:00

abstract：:Inflammatory myositis (IM) and myasthenia gravis (MG) are both immune disorders involving muscle. The concurrent presence of both conditions in the same patient is extremely rare and the diagnosis is important and challenging. Here, we report a case of concurrent myositis and myocarditis and MG without thymoma in a 69...

journal_title：Frontiers in neurology

authors： Zhou Z,Chen X,Liu G,Pu J,Wu J

更新日期：2019-07-16 00:00:00

abstract：:Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this fact is well known, there has been a remarkable lack of progress in determining the pathophysiological mechanisms behind fatigue and the establishment of effective treatments. The main barrier has been the lack of a unified...

journal_title：Frontiers in neurology

authors： Rudroff T,Kindred JH,Ketelhut NB

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:The neural constraints underlying hemiparetic gait dysfunction are associated with abnormal kinetic outflow and altered muscle synergy structure. Recent evidence from our lab implicates the lesioned hemisphere in mediating the expression of abnormally coupled hip adduction and knee extension synergy, suggest...

journal_title：Frontiers in neurology

authors： Tan AQ,Dhaher YY

更新日期：2017-08-07 00:00:00

abstract：:Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic transformation. While significant advances have been made over the past two decades with regard to emergent treatment of AIS, many of the therapeutic options are limited by an increased risk of hemorrhage. Here, we sought to review...

journal_title：Frontiers in neurology

authors： Sussman ES,Connolly ES Jr

更新日期：2013-06-10 00:00:00

abstract：:Manual dexterity measures can be useful for early detection of age-related functional decline and for prediction of cognitive decline. However, what aspects of sensorimotor function to assess remains unclear. Manual dexterity markers should be able to separate impairments related to cognitive decline from those relate...

journal_title：Frontiers in neurology

authors： Carment L,Abdellatif A,Lafuente-Lafuente C,Pariel S,Maier MA,Belmin J,Lindberg PG

更新日期：2018-10-29 00:00:00

abstract：:Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more frequently observed in infants of smoking mothers. The global prevalence of smoking during pregnancy is 1.7% and up to 8.1% of women in Europe smoke du...

journal_title：Frontiers in neurology

authors： Bednarczuk N,Milner A,Greenough A

更新日期：2020-10-23 00:00:00

abstract：:Studies suggest that microRNAs that regulate expression of matrix metalloproteinase (MMP)-9 may be involved in hemorrhagic transformation (HT) after cardioembolic stroke, so we examined whether such microRNAs could predict HT in acute cardioembolic stroke patients. Blood samples were prospectively collected from patie...

journal_title：Frontiers in neurology

authors： Zheng L,Xiong Y,Liu J,Yang X,Wang L,Zhang S,Liu M,Wang D

更新日期：2019-09-06 00:00:00

abstract：:Antiphospholipid syndrome (APS) is an autoimmune antibody-mediated condition characterized by thrombotic events and/or pregnancy morbidity in association with persistent positivity to antiphospholipid antibodies (aPL). The nervous system is frequently affected, as intracranial vessels are the most frequent site of art...

journal_title：Frontiers in neurology

authors： Fleetwood T,Cantello R,Comi C

更新日期：2018-11-26 00:00:00

abstract：:Background: Subthalamic nucleus deep brain stimulation (STN-DBS) has been an established method in improvement of motor disabilities in Parkinson's disease (PD) patients. It has been also claimed to have an impact on balance and gait disorders in PD patients, but the previous results are conflicting. Objective: The ai...

journal_title：Frontiers in neurology

authors： Szlufik S,Kloda M,Friedman A,Potrzebowska I,Gregier K,Mandat T,Przybyszewski A,Dutkiewicz J,Figura M,Habela P,Koziorowski D

更新日期：2018-10-31 00:00:00

abstract：:Stroke is the second leading cause of death and physical disability, with a global lifetime incidence rate of 1 in 6. Currently, the only FDA approved treatment for ischemic stroke is the administration of tissue plasminogen activator (tPA). Stem cell clinical trials for stroke have been underway for close to two deca...

journal_title：Frontiers in neurology

authors： Krause M,Phan TG,Ma H,Sobey CG,Lim R

更新日期：2019-06-25 00:00:00

abstract：:Objectives: This study aimed to assess the efficacy of minocycline for the treatment of acute ischemic stroke. Background: While there have been meta-analysis that surveyed the efficacy of minocycline in the treatment of acute stroke, they have some methodological limitations. We performed a new systematic review whic...

journal_title：Frontiers in neurology

authors： Sheng Z,Liu Y,Li H,Zheng W,Xia B,Zhang X,Yong VW,Xue M

更新日期：2018-12-20 00:00:00

abstract：:Background and Purpose: Internal carotid artery stenosis (ICAS)≥70% is a leading cause of ischemic cerebrovascular events (ICVEs). However, a considerable percentage of stroke survivors with symptomatic ICAS (sICAS) have <70% stenosis with a vulnerable plaque. Whether the length of ICAS is associated with high risk of...

journal_title：Frontiers in neurology

authors： Elhfnawy AM,Heuschmann PU,Pham M,Volkmann J,Fluri F

更新日期：2019-04-09 00:00:00

abstract：:Background and Purpose: The effect of uric acid (UA) levels on severity and prognosis of spontaneous intracerebral hemorrhage (ICH) remains controversial. We aimed to explore the association of admission UA levels with stroke severity and outcomes in ICH patients. Materials and Methods: The patients enrolled in this s...

journal_title：Frontiers in neurology

authors： Liu X,Cao Z,Gu H,Yang K,Ji R,Li Z,Zhao X,Wang Y

更新日期：2020-12-03 00:00:00

abstract：:Background: Ischemic stroke patients show alterations in peripheral leukocyte counts that may result from the sterile inflammation response as well as the occurrence of early infections. We here aimed to determine whether alterations of circulating leukocytes in acute ischemic stroke are associated with long-term func...

journal_title：Frontiers in neurology

authors： Semerano A,Strambo D,Martino G,Comi G,Filippi M,Roveri L,Bacigaluppi M

更新日期：2020-04-03 00:00:00

abstract：:Objective: The platelet-to-lymphocyte ratio (PLR) is a new marker of atherosclerotic inflammation and has been identified as a predictive factor in cardiovascular diseases, but its significance in patients with acute ischaemic stroke (AIS) who have undergone intravenous thrombolysis (IVT) is still unknown. Methods: Co...

journal_title：Frontiers in neurology

authors： Xu JH,He XW,Li Q,Liu JR,Zhuang MT,Huang FF,Bao GS

更新日期：2019-11-13 00:00:00

abstract：OBJECTIVE:To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS:Systematic literature search according to the preferred reporting it...

journal_title：Frontiers in neurology

authors： Macdonald NK,Kaski D,Saman Y,Al-Shaikh Sulaiman A,Anwer A,Bamiou DE

更新日期：2017-04-20 00:00:00