Antiphospholipid Syndrome and the Neurologist: From Pathogenesis to Therapy.

abstract：:Aim: The aim of the study was to investigate the effect of the onset of Parkinson's disease (PD) on life satisfaction. Method: Data from 2008, 2011, and 2014 were used from a population-based prospective cohort (German Ageing Survey; 8,982 observations in FE regression analysis) of community-residing individuals in th...

journal_title：Frontiers in neurology

authors： Buczak-Stec EW,König HH,Hajek A

更新日期：2018-07-25 00:00:00

abstract：:Disorders of the central nervous system sometimes cause severe sensory motor paralysis accompanied by gait impairment. Recently, there are several reports on the effectiveness of robot-assisted gait training for patients experiencing these issues. The purpose of this case report was to assess the neuromechanical effec...

journal_title：Frontiers in neurology

authors： Kadone H,Kubota S,Abe T,Noguchi H,Miura K,Koda M,Shimizu Y,Hada Y,Sankai Y,Suzuki K,Yamazaki M

更新日期：2020-03-31 00:00:00

abstract：Background and Objectives:Benign paroxysmal positional vertigo (BPPV) recurs frequently. This study aims to determine that each patient with BPPV has a predilection for a specific canal and the type of recurred BPPV can be predicted from that observed during the previous attack. Methods:The involved side (right, left,...

journal_title：Frontiers in neurology

authors： Kim HJ,Kim JS

更新日期：2017-12-15 00:00:00

abstract：BACKGROUND:Hypertension (HTN) is the most common cause of spontaneous intracerebral hemorrhage (ICH). The aim of this study is to investigate the role of resistant HTN in patients with ICH. METHODS AND RESULTS:We conducted a retrospective study of all consecutive ICH admissions at our medical center from November 2013...

journal_title：Frontiers in neurology

authors： Hong D,Stradling D,Dastur CK,Akbari Y,Groysman L,Al-Khoury L,Chen J,Small SL,Yu W

更新日期：2017-05-03 00:00:00

abstract：:Background and Aim: Reliable, valid and sensitive measures of dual-task-associated impairments in patients with Parkinson's disease (PD) may reveal progressive deficits unnoticed under single-task walking. The aim of this study was to quantitatively identify markers of progressive gait deficits in idiopathic PD while ...

journal_title：Frontiers in neurology

authors： Micó-Amigo ME,Kingma I,Heinzel S,Nussbaum S,Heger T,van Lummel RC,Berg D,Maetzler W,van Dieën JH

更新日期：2019-05-14 00:00:00

abstract：:Hemiconvulsion-hemiplegia-epilepsy syndrome (HHES) is a subset of acute encephalopathy characterized by infantile-onset with acute hemiconvulsive febrile status and subsequent unilateral cerebral atrophy and hemiparesis. In the chronic phase, patients with HHES develop epilepsy, typically displayed as intractable foca...

journal_title：Frontiers in neurology

authors： Itamura S,Okanishi T,Arai Y,Nishimura M,Baba S,Ichikawa N,Hirayama Y,Ishihara N,Hiraide T,Ishigaki H,Fukuda T,Otsuki Y,Enoki H,Fujimoto A

更新日期：2019-11-20 00:00:00

abstract：:With the advent of susceptibility-weighted imaging (SWI), the ability to identify cerebral microbleeds (CMBs) associated with mild traumatic brain injury (mTBI) has become increasingly commonplace. Nevertheless, the clinical significance of post-traumatic CMBs remains controversial partly because it is unclear whether...

journal_title：Frontiers in neurology

authors： Rostowsky KA,Maher AS,Irimia A

更新日期：2018-11-13 00:00:00

abstract：:Background: Intracranial carotid artery calcification (ICAC) on computed tomography (CT) is a marker of atherosclerosis and an independent predictor of vascular events including stroke. While vitamin K antagonists (VKAs) are used to prevent embolic stroke, they have been shown to increase levels of both coronary and e...

journal_title：Frontiers in neurology

authors： Peeters MTJ,Houben R,Postma AA,van Oostenbrugge RJ,Schurgers LJ,Staals J

更新日期：2019-12-20 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to systematically review the efficacy and tolerability of gabapentin in the treatment of sleep disturbance in patients with medical illness. METHODS:PubMed was searched for randomized, double-blinded, placebo-controlled trials that reported sleep changes during gabapent...

journal_title：Frontiers in neurology

authors： Liu GJ,Karim MR,Xu LL,Wang SL,Yang C,Ding L,Wang YF

更新日期：2017-07-14 00:00:00

abstract：:Background and Purpose: Stability stratification of intracranial aneurysms (IAs) is crucial for individualized clinical management, especially for small IAs. We aim to develop and validate a nomogram based on clinical and morphological risk factors for individualized instability stratification of small IAs. Methods: S...

journal_title：Frontiers in neurology

authors： Zhu W,Li W,Tian Z,Zhang M,Zhang Y,Wang K,Zhang Y,Yang X,Liu J

更新日期：2021-01-15 00:00:00

abstract：:Objective: To explore the clinical features and correlates of excessive daytime sleepiness (EDS) in a Chinese population of Parkinson's disease (PD) patients. Methods: Patients with clinically established or clinically probable PD were recruited. Clinical and demographic data were collected, and participants were eval...

journal_title：Frontiers in neurology

authors： Xiang YQ,Xu Q,Sun QY,Wang ZQ,Tian Y,Fang LJ,Yang Y,Tan JQ,Yan XX,Tang BS,Guo JF

更新日期：2019-02-19 00:00:00

abstract：:Background: Recent studies have shown that renal disease is associated with magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD), independent of traditional vascular risk factors. Although large artery lesions might be involved in the cerebrorenal association, evidence has been lacking. Met...

journal_title：Frontiers in neurology

authors： Ao DH,Zhai FF,Han F,Zhou LX,Ni J,Yao M,Zhang DD,Li ML,Fan XH,Jin ZY,Cui LY,Zhang SY,Zhu YC

更新日期：2018-06-26 00:00:00

abstract：:Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the characteristic loss of hand function and spoken language after the first year of life, people with RTT also have a variety of physiological and auton...

journal_title：Frontiers in neurology

authors： Ward CS,Huang TW,Herrera JA,Samaco RC,McGraw CM,Parra DE,Arvide EM,Ito-Ishida A,Meng X,Ure K,Zoghbi HY,Neul JL

更新日期：2020-10-30 00:00:00

abstract：:Background: External ventricular drain (EVD) has a major role in the management and monitoring of intracranial pressure (ICP) and its major complication is EVD infection. The risk factors for EVD infection are still a major topic of controversy, hence the need for further research. Objective: The objective of this rev...

journal_title：Frontiers in neurology

authors： Sorinola A,Buki A,Sandor J,Czeiter E

更新日期：2019-03-15 00:00:00

abstract：:Narcolepsy with cataplexy is a rare, but important differential diagnosis for daytime sleepiness and atonic paroxysms in an adolescent. A recent increase in incidence in the pediatric age group probably linked to the use of the Pandemrix influenza vaccine in 2009, has increased awareness that different environmental f...

journal_title：Frontiers in neurology

authors： Rosch RE,Farquhar M,Gringras P,Pal DK

更新日期：2016-08-10 00:00:00

abstract：:Background: Following aneurysmal subarachnoid hemorrhage, peripherally-drawn lactic acid has been associated with poor outcomes; however, its clinical significance is unknown. We investigated admission factors and patient outcomes associated with serum lactic acid in this population. Methods: This was a retrospective ...

journal_title：Frontiers in neurology

authors： Poblete RA,Cen SY,Zheng L,Emanuel BA

更新日期：2018-07-23 00:00:00

abstract：:Objective: To assess the relation between a sum score of imaging markers indicative of cerebral amyloid angiopathy (CAA) and cognitive impairment, stroke, dementia, and mortality in a general population. Methods: One thousand six hundred twenty-two stroke-free and dementia-free participants of the population-based Rot...

journal_title：Frontiers in neurology

authors： Yilmaz P,Ikram MA,Ikram MK,Niessen WJ,Viswanathan A,Charidimou A,Vernooij MW

更新日期：2019-12-06 00:00:00

abstract：:The relationship between circadian rhythm and epilepsy has been recognized for decades. Yet many questions underlying the complex mechanisms of their interaction remain elusive. A better understanding on this topic allows the development of accurate seizure-detection algorithm and alternative precise therapeutic strat...

journal_title：Frontiers in neurology

authors： Xu C,Yu J,Ruan Y,Wang Y,Chen Z

更新日期：2020-07-24 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:It is well-recognized that the gut microbiota (GM) is crucial for gut function, metabolism, and energy cycles. The GM also has effects on neurological outcomes via many mechanisms, such as metabolite production and the gut-brain axis. Emerging evidence has gradually indicated that GM dysbiosis plays a role in several ...

journal_title：Frontiers in neurology

authors： Yang D,Zhao D,Ali Shah SZ,Wu W,Lai M,Zhang X,Li J,Guan Z,Zhao H,Li W,Gao H,Zhou X,Yang L

更新日期：2019-11-06 00:00:00

abstract：:Mitochondrial complex III deficiency nuclear type 2 is an autosomal-recessive disorder caused by mutations in TTC19 gene. TTC19 is involved in the preservation of mitochondrial complex III, which is responsible for transfer of electrons from reduced coenzyme Q to cytochrome C and thus, contributes to the formation of ...

journal_title：Frontiers in neurology

authors： Habibzadeh P,Inaloo S,Silawi M,Dastsooz H,Farazi Fard MA,Sadeghipour F,Faghihi Z,Rezaeian M,Yavarian M,Böhm J,Faghihi MA

更新日期：2019-09-04 00:00:00

abstract：:Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advance of the sleep-wake...

journal_title：Frontiers in neurology

authors： Polymeropoulos CM,Mohrman MA,Keefe MS,Brzezynski JL,Wang J,Prokosch LS,Polymeropoulos VM,Xiao C,Birznieks G,Polymeropoulos MH

更新日期：2020-07-09 00:00:00

abstract：BACKGROUND:An estimated 30-50% of essential tremor (ET) diagnoses are incorrect, and the true diagnosis in those patients is often Parkinson's disease (PD) or other tremor disorders. There are general statements about the tremor in these ET and PD, but published data on the more subtle characteristics of tremor are sur...

journal_title：Frontiers in neurology

authors： Sternberg EJ,Alcalay RN,Levy OA,Louis ED

更新日期：2013-05-10 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.578924.]. ...

journal_title：Frontiers in neurology

authors： Binck S,Pauly C,Vaillant M,Hipp G,Gantenbein M,Krueger R,Diederich NJ

更新日期：2021-01-12 00:00:00

abstract：OBJECTIVES:Stroke can happen to people away from home. It is unknown whether non-resident and resident stroke patients have equal access to thrombolysis. MATERIALS AND METHODS:Consecutive patients cared for by the Stroke Emergency Mobile between 2011 and 2016 after prompting suspicion of acute stroke during the emerge...

journal_title：Frontiers in neurology

authors： Schlemm L,Turc G,Audebert HJ,Ebinger M

更新日期：2017-06-30 00:00:00

abstract：:Introduction: Recent studies of patients with multiple sclerosis (MS) have revealed disturbances in distinct components of social cognition, such as impaired mentalizing and empathy. The present study investigated this socio-cognitive profile in MS patients in more detail, by examining their performance on tasks measu...

journal_title：Frontiers in neurology

authors： Czekóová K,Shaw DJ,Saxunová K,Dufek M,Mareček R,Vaníček J,Brázdil M

更新日期：2019-05-21 00:00:00

abstract：:Background: Tuberculous meningitis (TBM) is an extremely devastating inflammation of the central nervous system; however, no available optimum treatment can effectively control the disease so far. Method: The medical records of TBM patients from May 2011 to August 2016 in West China hospital were retrospectively analy...

journal_title：Frontiers in neurology

authors： Abdulaziz ATA,Ren YM,Li W,Li JM,Zhou D

更新日期：2019-06-13 00:00:00

abstract：:Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more frequently observed in infants of smoking mothers. The global prevalence of smoking during pregnancy is 1.7% and up to 8.1% of women in Europe smoke du...

journal_title：Frontiers in neurology

authors： Bednarczuk N,Milner A,Greenough A

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND AND PURPOSE:The presence of aortic atherosclerosis is an independent risk factor for secondary stroke. The present study was designed to have an initial exploration of the correlation between the load and extent of aortic atheroma (AA) and initial stroke severity or clinical outcome 3 months after stroke. M...

journal_title：Frontiers in neurology

authors： Lazzaro MA,Zaidat OO,Issa MA,Gilkeson RC,Sunshine JL,Tarr RW,Husain S,Suarez JI

更新日期：2011-03-21 00:00:00

abstract：:Cognitive dysfunction is a significant non-motor feature of Parkinson's disease, with the risk of dementia increasing with prolonged disease duration. Multiple cognitive domains are affected, and the pathophysiology cannot be explained by dopaminergic loss alone. Sophisticated neuroimaging techniques can detect the na...

journal_title：Frontiers in neurology

authors： Sasikumar S,Strafella AP

更新日期：2020-01-31 00:00:00