Stroke severity predicted by aortic atheroma detected by ultra-fast and cardiac-gated chest tomography.

abstract：:Mutations in the Potassium channel subfamily T member 1 (KCNT1) gene have been reported in a range of epileptic encephalopathies. Here we report the case of a 12-year-old male suffering from multiple types of epileptic seizures and cognitive decline from the age of 10. The patient had four types of epileptic seizures,...

journal_title：Frontiers in neurology

authors： Jia Y,Lin Y,Li J,Li M,Zhang Y,Hou Y,Liu A,Zhang L,Li L,Xiang P,Ye J,Huang Z,Wang Y

更新日期：2019-02-05 00:00:00

abstract：:Many neurodegenerative disorders are associated with rapid eye movement sleep (REMS) loss; however, the mechanism was unknown. As REMS loss elevates noradrenaline (NA) level in the brain as well as induces neuronal apoptosis and degeneration, in this study, we have delineated the intracellular molecular pathway involv...

journal_title：Frontiers in neurology

authors： Somarajan BI,Khanday MA,Mallick BN

更新日期：2016-03-07 00:00:00

abstract：:Cerebral microbleeds (microbleeds) are small, punctuate hypointense lesions seen in T2* Gradient-Recall Echo (GRE) and Susceptibility-Weighted (SWI) Magnetic Resonance Imaging (MRI) sequences, corresponding to areas of hemosiderin breakdown products from prior microscopic hemorrhages. They occur in the setting of impa...

journal_title：Frontiers in neurology

authors： Yates PA,Villemagne VL,Ellis KA,Desmond PM,Masters CL,Rowe CC

更新日期：2014-01-06 00:00:00

abstract：:Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and epilepsy. Comprehending how these interact with each other may help to advance our understanding of the pathophysiology of epilepsy and develop new treatment strategies to improve seizure control by reducing the medication side ...

journal_title：Frontiers in neurology

authors： Jin B,Aung T,Geng Y,Wang S

更新日期：2020-05-08 00:00:00

abstract：:The pool of neural stem and progenitor cells (NSPCs) in the dentate gyrus of the hippocampus is reduced by ionizing radiation. This explains, at least partly, the learning deficits observed in patients after radiotherapy, particularly in pediatric cases. An 8 Gy single irradiation dose was delivered to the whole brain...

journal_title：Frontiers in neurology

authors： Sato Y,Shinjyo N,Sato M,Nilsson MKL,Osato K,Zhu C,Pekna M,Kuhn HG,Blomgren K

更新日期：2018-09-11 00:00:00

abstract：OBJECTIVE:Tinnitus is a common symptom of hearing impairment. Patients who are bilaterally hard of hearing are often affected by tinnitus. However, they cannot undergo any of the standard tinnitus therapies, since they rely on hearing. Cochlear implantation (CI) used to treat severe hearing disabilities, such as bilate...

journal_title：Frontiers in neurology

authors： Knopke S,Szczepek AJ,Häussler SM,Gräbel S,Olze H

更新日期：2017-04-25 00:00:00

abstract：:Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB) are common causes of dementia worldwide. Although considered separate entities based on the relative temporal onset of motor symptoms vs. diagnosis of dementia, it is unknown if these diseases truly have distinct cognitive profiles. We hypothesized...

journal_title：Frontiers in neurology

authors： Aldridge GM,Birnschein A,Denburg NL,Narayanan NS

更新日期：2018-03-12 00:00:00

abstract：:Background: Patients with traumatic brain injury (TBI) exhibit a variable and unpredictable outcome. The proteins interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have shown predictive values for the presence of intracranial lesions. Aim: To evaluate the individual and combined outcome prediction a...

journal_title：Frontiers in neurology

authors： Lagerstedt L,Azurmendi L,Tenovuo O,Katila AJ,Takala RSK,Blennow K,Newcombe VFJ,Maanpää HR,Tallus J,Hossain I,van Gils M,Menon DK,Hutchinson PJ,Zetterberg H,Posti JP,Sanchez JC

更新日期：2020-06-02 00:00:00

abstract：:Attention impairment may provide a cohesive neurobiological explanation for clusters of clinical symptoms that occur after a concussion; therefore, objective quantification of attention is needed. Visually tracking a moving target is an attention-dependent sensorimotor function, and eye movement can be recorded easily...

journal_title：Frontiers in neurology

authors： Maruta J,Spielman LA,Rajashekar U,Ghajar J

更新日期：2018-07-26 00:00:00

abstract：:Objective: A number of studies have reported that aldehyde dehydrogenase-2 (ALDH2) polymorphisms maybe associated with the risk of Alzheimer's disease (AD) and Parkinson's disease (PD). However, the results of such studies are inconsistent. We therefore conducted a meta-analysis to clarify the association between ALDH...

journal_title：Frontiers in neurology

authors： Chen J,Huang W,Cheng CH,Zhou L,Jiang GB,Hu YY

更新日期：2019-03-28 00:00:00

abstract：:GNE myopathy is characterized by distal muscle weakness, and caused by recessive mutations in GNE. Its onset is characteristically in young adulthood, although a broad spectrum of onset age is known to exist. A large number of mutations in GNE are pathogenic and this clinical phenotype can be difficult to differentiat...

journal_title：Frontiers in neurology

authors： Soule T,Phan C,White C,Resch L,Lacson A,Martens K,Pfeffer G

更新日期：2018-11-08 00:00:00

abstract：:Background: External ventricular drain (EVD) has a major role in the management and monitoring of intracranial pressure (ICP) and its major complication is EVD infection. The risk factors for EVD infection are still a major topic of controversy, hence the need for further research. Objective: The objective of this rev...

journal_title：Frontiers in neurology

authors： Sorinola A,Buki A,Sandor J,Czeiter E

更新日期：2019-03-15 00:00:00

abstract：:Background: Neurofilament light chain (NFL) was believed to be a promising biomarker for the diagnosis of Amyotrophic lateral sclerosis (ALS) and disease burden evaluation. Objective: To determine the serum NFL level and its clinical relevance, including its association with disease severity [evaluated by the ALS Func...

journal_title：Frontiers in neurology

authors： Sugimoto K,Han Y,Song Y,Gao Y

更新日期：2020-12-03 00:00:00

abstract：:Background: Regional cerebral oxygen saturation (rScO2) measured by near-infrared spectroscopy (NIRS) can be used to monitor brain oxygenation in extracorporeal membrane oxygenation (ECMO). ECMO patients that develop acute brain injuries (ABIs) are observed to have worse outcomes. We evaluated the association between ...

journal_title：Frontiers in neurology

authors： Khan I,Rehan M,Parikh G,Zammit C,Badjatia N,Herr D,Kon Z,Hogue C,Mazzeffi M

更新日期：2018-11-23 00:00:00

abstract：OBJECTIVE:Morphological changes of recent small subcortical infarcts are not well defined. The purpose of the present study was to describe the MRI characteristics of the evolution for this stroke subtype. METHODS:We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subco...

journal_title：Frontiers in neurology

authors： Okazaki S,Hornberger E,Griebe M,Gass A,Hennerici MG,Szabo K

更新日期：2015-05-26 00:00:00

abstract：:In task-specific focal hand dystonia (tspFHD), the temporal dynamics of cortical activity in the motor system and how these processes are related to impairments in sensory and motor function are poorly understood. Here, we use time-frequency reconstructions of magnetoencephalographic (MEG) data to elaborate the tempor...

journal_title：Frontiers in neurology

authors： Hinkley LB,Dolberg R,Honma S,Findlay A,Byl NN,Nagarajan SS

更新日期：2012-11-28 00:00:00

abstract：:Between seizures, irritative network generates frequent brief synchronous activity, which manifests on the EEG as interictal epileptiform discharges (IEDs). Recent insights into the mechanism of IEDs at the microscopic level have demonstrated a high variance in the recruitment of neuronal populations generating IEDs a...

journal_title：Frontiers in neurology

authors： Janca R,Krsek P,Jezdik P,Cmejla R,Tomasek M,Komarek V,Marusic P,Jiruska P

更新日期：2018-03-23 00:00:00

abstract：BACKGROUND:Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied. METHODS:We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range ...

journal_title：Frontiers in neurology

authors： Shalaby S,Indes J,Keung B,Gottschalk CH,Machado D,Patel A,Robakis D,Louis ED

更新日期：2016-04-22 00:00:00

abstract：:The relaxation rates and contractile properties of inspiratory muscles are altered with inspiratory muscle weakness and fatigue. This fact plays an important role in neuromuscular disorders patients and had never been extensively studied in amyotrophic lateral sclerosis (ALS). In this cross-sectional study, these para...

journal_title：Frontiers in neurology

authors： Sarmento A,Aliverti A,Marques L,Pennati F,Dourado-Júnior ME,Fregonezi G,Resqueti V

更新日期：2018-05-02 00:00:00

abstract：:Cerebral venous sinus thrombosis (CVST) is a relatively uncommon cause of stroke more often affecting women and younger individuals. Blockage of the venous outflow rapidly causes edema and space-occupying venous infarctions and it seems intuitive that decompressive craniectomy (DC) can effectively reduce intracranial ...

journal_title：Frontiers in neurology

authors： Avanali R,Gopalakrishnan MS,Devi BI,Bhat DI,Shukla DP,Shanbhag NC

更新日期：2019-05-15 00:00:00

abstract：:Objective: Status epilepticus is a major emergency condition. The choice of antiepileptic drugs for second-line treatment after benzodiazepine remains controversial, including levetiracetam vs. fosphenytoin. We compare the safety of intravenous levetiracetam and fosphenytoin as a second-line treatment in patients with...

journal_title：Frontiers in neurology

authors： Nakamura K,Ohbe H,Matsui H,Takahashi Y,Marushima A,Inoue Y,Fushimi K,Yasunaga H

更新日期：2020-07-02 00:00:00

abstract：:Preterm-born infants frequently suffer from an array of neurological damage, collectively termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting with a neurodevelopmental disorder (e.g., autism spectrum disorder; attention deficit hyperactivity disorder) later in life. It is hypothe...

journal_title：Frontiers in neurology

authors： Fleiss B,Gressens P,Stolp HB

更新日期：2020-07-14 00:00:00

abstract：:Background: Increasing evidence indicates that early radiation-induced subtle cerebral changes may be the precursors to permanent brain dysfunction at the late-delayed (LDS) post-radiotherapy (RT) stage. In this study, we aim to track the RT-related longitudinal brain activity in nasopharyngeal carcinoma (NPC) patient...

journal_title：Frontiers in neurology

authors： Yang Y,Lin X,Li J,Han L,Li Z,Liu S,Hou G,Xie C,Lv X,Qiu Y

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Before implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine. Therefore, in this study, we compared the analytical performance o...

journal_title：Frontiers in neurology

authors： van Waalwijk van Doorn LJC,Kulic L,Koel-Simmelink MJA,Kuiperij HB,Versleijen AAM,Struyfs H,Twaalfhoven HAM,Fourier A,Engelborghs S,Perret-Liaudet A,Lehmann S,Verbeek MM,Vanmechelen EJM,Teunissen CE

更新日期：2017-07-03 00:00:00

abstract：:Background: The sequence effect (SE), referring to step-to-step reduction in amplitude, is considered to lead to freezing of gait (FOG) in Parkinson's disease (PD). Visual cues may alleviate SE and help reduce freezing episodes. FOG patients show significant SE prior to turning or toward a doorway, but the SE toward a...

journal_title：Frontiers in neurology

authors： Cao SS,Yuan XZ,Wang SH,Taximaimaiti R,Wang XP

更新日期：2020-08-12 00:00:00

abstract：:Although orthodontic treatment is common, orthodontic force often induced pain. Low-level laser therapy (LLLT) has been investigated to improve therapeutic comfort. In dentistry, LLLT is mainly applied using two types of lasers, CO2 and diode lasers, whose biological actions are thought to be associated with wavelengt...

journal_title：Frontiers in neurology

authors： Tsuchiya T,Hasegawa N,Yugawa M,Sasaki A,Suda N,Adachi K

更新日期：2020-06-05 00:00:00

abstract：:Background: Transcranial direct current stimulation (tDCS) and therapy-based virtual reality (VR) have been investigated separately. They have shown promise as efficient and engaging new tools in the neurological rehabilitation of individuals with cerebral palsy (CP). However, the recent literature encourages investig...

journal_title：Frontiers in neurology

authors： da Silva TD,Fontes AMGG,de Oliveira-Furlan BS,Roque TT,Lima AII,de Souza BMM,Alberissi CAO,Silveira AC,de Moraes ÍAP,Collett J,Silva RP,Airoldi MJ,Ribeiro-Papa DC,Dawes H,Monteiro CBM

更新日期：2020-09-02 00:00:00

abstract：:A synthetic peptide with antisecretory activity, antisecretory factor (AF)-16, improves injury-related deficits in water and ion transport and decreases intracranial pressure after experimental cold lesion injury and encephalitis although its role in traumatic brain injury (TBI) is unknown. AF-16 or an inactive refere...

journal_title：Frontiers in neurology

authors： Clausen F,Hansson HA,Raud J,Marklund N

更新日期：2017-02-14 00:00:00

abstract：Introduction:There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal designs. Aim:We investigated the differences in cognitive decline in AD compared to DLB over 4 ye...

journal_title：Frontiers in neurology

authors： Breitve MH,Chwiszczuk LJ,Brønnick K,Hynninen MJ,Auestad BH,Aarsland D,Rongve A

更新日期：2018-03-06 00:00:00

abstract：:Background and Purpose: The effect of uric acid (UA) levels on severity and prognosis of spontaneous intracerebral hemorrhage (ICH) remains controversial. We aimed to explore the association of admission UA levels with stroke severity and outcomes in ICH patients. Materials and Methods: The patients enrolled in this s...

journal_title：Frontiers in neurology

authors： Liu X,Cao Z,Gu H,Yang K,Ji R,Li Z,Zhao X,Wang Y

更新日期：2020-12-03 00:00:00