Sleep Duration and Stroke: A Mendelian Randomization Study.

abstract：:A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thinking, fear and wor...

journal_title：Frontiers in neurology

authors： Naylor B,Hesam-Shariati N,McAuley JH,Boag S,Newton-John T,Rae CD,Gustin SM

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:A possible link between 3D movies and headache (HA) has never been a target of specific and systematic investigations. The aim of this study was to investigate the relationship between 3D cinema and HA and to evaluate possible risk factors of developing HA during or after watching a 3D movie. METHODS:This w...

journal_title：Frontiers in neurology

authors： Braschinsky M,Raidvee A,Sabre L,Zmachinskaja N,Zukovskaja O,Karask A,Saar B,Rakitin A

更新日期：2016-03-23 00:00:00

abstract：:Vestibular impairment has become a frequent consequence following blast-related traumatic brain injury (bTBI) in military personnel and Veterans. Behavioral outcomes such as depression, fear and anxiety are also common comorbidities of bTBI. To accelerate pre-clinical research and therapy developments, there is a need...

journal_title：Frontiers in neurology

authors： Dickerson MR,Bailey ZS,Murphy SF,Urban MJ,VandeVord PJ

更新日期：2020-07-15 00:00:00

abstract：Objective:We investigated the reliability and accuracy of a bedside diagnostic algorithm for patients presenting with vertigo/unsteadiness to the emergency department. Methods:We enrolled consecutive adult patients presenting with vertigo/unsteadiness at a tertiary hospital. STANDING, the acronym for the four-step alg...

journal_title：Frontiers in neurology

authors： Vanni S,Pecci R,Edlow JA,Nazerian P,Santimone R,Pepe G,Moretti M,Pavellini A,Caviglioli C,Casula C,Bigiarini S,Vannucchi P,Grifoni S

更新日期：2017-11-07 00:00:00

abstract：:Cerebral ischemia is the leading cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Although 70% of the patients show angiographic vasospasm only 30% develop symptomatic vasospasm defined as delayed cerebral ischemia (DCI). Early detection and management of reversible ischemia is of c...

journal_title：Frontiers in neurology

authors： Rostami E,Engquist H,Johnson U,Howells T,Ronne-Engström E,Nilsson P,Hillered L,Lewén A,Enblad P

更新日期：2014-06-02 00:00:00

abstract：:Introduction: Eslicarbazepine acetate (ESL) is an antiepileptic drug approved as monotherapy or add-on for the treatment of epilepsy with seizures of focal onset. ESL owns a good profile in terms of efficacy and tolerability, but its effects on EEG activity and connectivity are unknown. The purpose of this study was t...

journal_title：Frontiers in neurology

authors： Pellegrino G,Mecarelli O,Pulitano P,Tombini M,Ricci L,Lanzone J,Brienza M,Davassi C,Di Lazzaro V,Assenza G

更新日期：2018-12-11 00:00:00

abstract：:Background and Purpose: The effect of uric acid (UA) levels on severity and prognosis of spontaneous intracerebral hemorrhage (ICH) remains controversial. We aimed to explore the association of admission UA levels with stroke severity and outcomes in ICH patients. Materials and Methods: The patients enrolled in this s...

journal_title：Frontiers in neurology

authors： Liu X,Cao Z,Gu H,Yang K,Ji R,Li Z,Zhao X,Wang Y

更新日期：2020-12-03 00:00:00

abstract：:Stroke is a leading cause of death and disability worldwide. While various risk factors have been identified, sleep has only been considered a risk factor more recently. Various epidemiologic studies have associated stroke with sleep such as sleep duration, and laboratory and clinical studies have proposed various und...

journal_title：Frontiers in neurology

authors： Phua CS,Jayaram L,Wijeratne T

更新日期：2017-08-08 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (SICH) is the most lethal type of stroke. Half of these deaths occur within the acute phase. Frequently observed deterioration during the acute phase is often due to rebleeding or peri-hematomal expansion. The exact pathogenesis that leads to rebleeding or peri-hemorrhagic edema re...

journal_title：Frontiers in neurology

authors： Babi MA,James ML

更新日期：2017-01-19 00:00:00

abstract：:Introduction: Few studies have examined the motor, cognitive, and emotional factors involved in effective money management in persons with multiple sclerosis (MS). The aim of this study was to assess money management in persons MS and examine whether cognitive, motor, and emotional processes can predict money manageme...

journal_title：Frontiers in neurology

authors： Yael G,Nancy C,John D

更新日期：2019-10-23 00:00:00

abstract：:Background: Spinal and Bulbar Muscular Atrophy (SBMA) is caused by the extension of the polyglutamine tract within the androgen receptor (AR) gene, and results in a multisystem presentation, including the degeneration of lower motor neurons. The androgen receptor (AR) is known to modulate the expression of endogenous ...

journal_title：Frontiers in neurology

authors： Rex C,Nadeau MJ,Douville R,Schellenberg K

更新日期：2019-09-04 00:00:00

abstract：:To date, conflicting results about the role of vitamins in amyotrophic lateral sclerosis (ALS) have been reported along with a lack of systematic studies on all types of serum vitamins in patients with ALS. Moreover, extensive studies have been conducted on vitamins in other neurodegenerative diseases; however, whethe...

journal_title：Frontiers in neurology

authors： Wang M,Liu Z,Sun W,Yuan Y,Jiao B,Zhang X,Shen L,Jiang H,Xia K,Tang B,Wang J

更新日期：2020-06-18 00:00:00

abstract：:Introduction: Symptoms following a mild traumatic brain injury (mTBI) usually resolve quickly but may persist past 3 months in up to 15% of children. Mechanisms of mTBI recovery are poorly understood, but may involve alterations in cortical neurophysiology. Transcranial Magnetic Stimulation (TMS) can non-invasively in...

journal_title：Frontiers in neurology

authors： King R,Kirton A,Zewdie E,Seeger TA,Ciechanski P,Barlow KM

更新日期：2019-05-17 00:00:00

abstract：:Disrupted sleep is more common in older adults (OLD) than younger adults (YOUNG), often co-morbid with other conditions. How these sleep disturbances affect cognitive performance is an area of active study. We examined whether brain activation during verbal encoding correlates with sleep quantity and quality the night...

journal_title：Frontiers in neurology

authors： Jonelis MB,Drummond SP,Salamat JS,McKenna BS,Ancoli-Israel S,Bondi MW

更新日期：2012-04-03 00:00:00

abstract：:Background: Prolonged static whole-body roll-tilt has been shown to bias estimates of the direction of gravity when assessed by static paradigms such as the subjective visual vertical and the subjective haptic vertical. Objective: We hypothesized that these shifts are paradigm-independent and thus predicted a post-til...

journal_title：Frontiers in neurology

authors： Wedtgrube A,Bockisch CJ,Straumann D,Tarnutzer AA

更新日期：2020-10-15 00:00:00

abstract：:The identification of ocular tremor in a small cohort of patients with Parkinson's disease (PD) had lay somewhat dormant until the recent report of a pervasive ocular tremor as a universal finding in a large PD cohort that was, however, generally absent from a cohort of age-matched healthy subjects. The reported tremo...

journal_title：Frontiers in neurology

authors： Kaski D,Bronstein AM

更新日期：2017-04-24 00:00:00

abstract：:Objective: Simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) were applied to investigate the abnormalities in the topological characteristics of functional brain networks during non-rapid eye movement(NREM)sleep. And we investigated its relationship with cognitive abnormalities...

journal_title：Frontiers in neurology

authors： Zhu X,Ni K,Tan H,Liu Y,Zeng Y,Yu B,Guo Q,Xiao L

更新日期：2021-01-11 00:00:00

abstract：:Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved functional recovery. Here, we implant polyimide-based mircroelectrodes o...

journal_title：Frontiers in neurology

authors： Srinivasan S,Vyas K,McAvoy M,Calvaresi P,Khan OF,Langer R,Anderson DG,Herr H

更新日期：2019-03-22 00:00:00

abstract：BACKGROUND:Parasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches. However, neurochemical mechanisms of cholinergic regulation of peripheral nociception in meninges, origin pl...

journal_title：Frontiers in neurology

authors： Shelukhina I,Mikhailov N,Abushik P,Nurullin L,Nikolsky EE,Giniatullin R

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the presence of cavitating lacunes on brain imaging may have prognostic implications, the modifiable risk factors underlying these frequently observed lesions are not completely understood. We sought to determine if fasting and post-challenge triglycerides associate with cavitating lacun...

journal_title：Frontiers in neurology

authors： Leonards CO,Wang L,Fiebach JB,Endres M,Ebinger M

更新日期：2013-07-10 00:00:00

abstract：:Recent studies have demonstrated that exosomal microRNAs (miRNAs) are novel biomarkers and therapeutic targets for various diseases including vascular disease. However, specific exosomal miRNAs expression in stroke patients has not been reported yet. Here, we explored whether circulating exosomal miRNAs can serve as p...

journal_title：Frontiers in neurology

authors： Chen Y,Song Y,Huang J,Qu M,Zhang Y,Geng J,Zhang Z,Liu J,Yang GY

更新日期：2017-02-27 00:00:00

abstract：:Background and Purpose: This study aimed to investigate the efficacy of cerebrospinal fluid shunt intervention for idiopathic normal pressure hydrocephalus (iNPH) using data from a nationwide epidemiological survey in Japan. Methods: We conducted a cross-sectional study using data from a nationwide epidemiological sur...

journal_title：Frontiers in neurology

authors： Nakajima M,Miyajima M,Ogino I,Akiba C,Kawamura K,Kurosawa M,Kuriyama N,Watanabe Y,Fukushima W,Mori E,Kato T,Sugano H,Karagiozov K,Arai H

更新日期：2018-06-07 00:00:00

abstract：:Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past 75 years, pioneering head injury researchers have devised and tested a number ...

journal_title：Frontiers in neurology

authors： Lyeth BG

更新日期：2016-12-02 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00

abstract：:It is known that patients with severe motor and intellectual disabilities (SMID) showed sudden unexplained death (SUD), in which autopsy failed to identify causes of death. Although the involvement of brainstem dysfunction is speculated, the detailed neuropathological analysis still remains to be performed. In order t...

journal_title：Frontiers in neurology

authors： Hayashi M,Sakuma H

更新日期：2016-06-27 00:00:00

abstract：:Objective: Episodic memory is frequently impaired in Multiple Sclerosis (MS), but the cognitive characteristics and neuropsychological processes involved remain controversial. Our aim was to study episodic memory dysfunction in MS, using the LASSI-L, a novel memory-based cognitive stress test that uses a new paradigm ...

journal_title：Frontiers in neurology

authors： Matias-Guiu JA,Cortés-Martínez A,Curiel RE,Delgado-Álvarez A,Fernández-Oliveira A,Pytel V,Montero P,Moreno-Ramos T,Loewenstein DA,Matías-Guiu J

更新日期：2020-04-21 00:00:00

abstract：:Multiple sclerosis (MS) pathology progressively affects multiple central nervous system (CNS) areas. Due to this fact, MS produces a wide array of symptoms. Symptomatic therapy of one MS symptom can cause or worsen other unwanted symptoms (anticholinergics used for bladder dysfunction produce impairment of cognition, ...

journal_title：Frontiers in neurology

authors： Fernández Ó,Costa-Frossard L,Martínez-Ginés M,Montero P,Prieto JM,Ramió L

更新日期：2020-03-17 00:00:00

abstract：:Background: Data on clinical presentation of Hemiplegic Migraine (HM) are quite limited in the literature, particularly in the pediatric age. The aim of the present study is to describe in detail the phenotypic features at onset and during the first years of disease of sporadic (SHM) and familial (FHM) pediatric hemip...

journal_title：Frontiers in neurology

authors： Toldo I,Brunello F,Morao V,Perissinotto E,Valeriani M,Pruna D,Tozzi E,Moscano F,Farello G,Frusciante R,Carotenuto M,Lisotto C,Ruffatti S,Maggioni F,Termine C,Di Rosa G,Nosadini M,Sartori S,Battistella PA

更新日期：2019-10-15 00:00:00

abstract：:This study describes two experiments that were conducted in search for a behavioral paradigm to test for tinnitus in guinea pigs. Conditioning paradigms are available to determine the presence of tinnitus in animals and are based on the assumption that tinnitus impairs their ability to detect silent intervals in conti...

journal_title：Frontiers in neurology

authors： Heeringa AN,Agterberg MJ,van Dijk P

更新日期：2014-10-15 00:00:00

abstract：:Objective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization. Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal aneurysms treated ...

journal_title：Frontiers in neurology

authors： Sheng B,Wu D,Yuan J,Xu S,Li Z,Dong J,Lai N,Fang X

更新日期：2019-04-25 00:00:00