Glial Activation in the Thalamus Contributes to Vestibulomotor Deficits Following Blast-Induced Neurotrauma.

abstract：:Psychophysiological investigations of traumatic brain injury (TBI) are being conducted for several reasons, including the objective of learning more about the underlying physiological mechanisms of the pathological processes that can be initiated by a head injury. Additional goals include the development of objective ...

journal_title：Frontiers in neurology

authors： Rapp PE,Rosenberg BM,Keyser DO,Nathan D,Toruno KM,Cellucci CJ,Albano AM,Wylie SA,Gibson D,Gilpin AM,Bashore TR

更新日期：2013-07-22 00:00:00

abstract：:Background: Listeria rhombencephalitis, infection of the brainstem with Listeria monocytogenes, occurs mainly in humans and farmed ruminants and is associated with high fatality rates. Small ruminants (goats and sheep) are a large animal model due to neuropathological similarities. The purpose of this study was to def...

journal_title：Frontiers in neurology

authors： Precht C,Vermathen P,Henke D,Staudacher A,Lauper J,Seuberlich T,Oevermann A,Schweizer-Gorgas D

更新日期：2020-12-14 00:00:00

abstract：:Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advance of the sleep-wake...

journal_title：Frontiers in neurology

authors： Polymeropoulos CM,Mohrman MA,Keefe MS,Brzezynski JL,Wang J,Prokosch LS,Polymeropoulos VM,Xiao C,Birznieks G,Polymeropoulos MH

更新日期：2020-07-09 00:00:00

abstract：:Purpose: We are aiming to build a supervised machine learning-based classifier, in order to preoperatively distinguish focal cortical dysplasia (FCD) from glioneuronal tumors (GNTs) in patients with epilepsy. Methods: This retrospective study was comprised of 96 patients who underwent epilepsy surgery, with the final ...

journal_title：Frontiers in neurology

authors： Guo Y,Liu Y,Ming W,Wang Z,Zhu J,Chen Y,Yao L,Ding M,Shen C

更新日期：2020-11-24 00:00:00

abstract：:Traumatic brain injury (TBI) due to explosive blast exposure is a leading combat casualty. It is also implicated as a key contributor to war related mental health diseases. A clinically important consequence of all types of TBI is a high risk for development of seizures and epilepsy. Seizures have been reported in pat...

journal_title：Frontiers in neurology

authors： Kovacs SK,Leonessa F,Ling GS

更新日期：2014-04-09 00:00:00

abstract：:Autoimmune encephalitis often causes acute psychiatric symptoms and epileptic seizures. However, it is becoming increasingly clear that depending on the target antigen both symptoms and disease severity may vary. Furthermore, the identification and characterization of antibody subtypes are highly relevant for personal...

journal_title：Frontiers in neurology

authors： Edwin Thanarajah S,Prüss H,Warnke C,Barbe MT,Schroeter M,Fink GR,Onur OA

更新日期：2019-03-05 00:00:00

abstract：:During neurorehabilitation, clinical measurements are widely adopted to evaluate behavioral improvements after treatment. However, it is not able to identify or monitor the change of central nervous system (CNS) of each individual patient. Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely u...

journal_title：Frontiers in neurology

authors： Ge Y,Pan Y,Wu Q,Dou W

更新日期：2019-11-01 00:00:00

abstract：:Objectives: Elevated neurofilament light chain (NFL) levels within the cerebrospinal fluid (CSF) are a biomarker representing axonal neurodegeneration in rapid progressive neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). It is unclear to what extent the levels of NFL increase in the CSF (CSF-NFL...

journal_title：Frontiers in neurology

authors： Pawlitzki M,Schreiber S,Bittner D,Kreipe J,Leypoldt F,Rupprecht K,Carare RO,Meuth SG,Vielhaber S,Körtvélyessy P

更新日期：2018-12-14 00:00:00

abstract：Background:The electrophysiological evidence supporting the therapeutic efficacy of multiple transcranial direct current stimulation (tDCS) sessions on consciousness improvement in patients with prolonged disorders of consciousness (DOCs) has not been firmly established. Objectives:To assess the effects of repeated tD...

journal_title：Frontiers in neurology

authors： Zhang Y,Song W,Du J,Huo S,Shan G,Li R

更新日期：2017-11-21 00:00:00

abstract：:Sensorineural hearing loss is the most common long-term deficit after pneumococcal meningitis (PM), occurring in up to 30% of surviving patients. The infection and the following overshooting inflammatory host response damage the vulnerable sensory cells of the inner ear, resulting in loss of hair cells and spiral gang...

journal_title：Frontiers in neurology

authors： Erni ST,Fernandes G,Buri M,Perny M,Rutten RJ,van Noort JM,Senn P,Grandgirard D,Roccio M,Leib SL

更新日期：2019-06-10 00:00:00

abstract：Background:There is increasing interest in stem cell therapy as another treatment modality in stroke, particularly for patients who are unable to receive endovascular clot retrieval or thrombolysis therapies, or for whom standard treatment has failed. We have recently shown that human amniotic epithelial cells (hAECs) ...

journal_title：Frontiers in neurology

authors： Phan TG,Ma H,Lim R,Sobey CG,Wallace EM

更新日期：2018-06-07 00:00:00

abstract：:Stroke is becoming one of the leading causes of adult disability and death in sub-Saharan African countries. The aim of the present study is to provide an up-to-date account of the clinical and demographic characteristics of patients with stroke admitted to the University of Gondar College of Medicine and Health Scien...

journal_title：Frontiers in neurology

authors： Baye M,Hintze A,Gordon-Murer C,Mariscal T,Belay GJ,Gebremariam AA,Hughes CML

更新日期：2020-05-19 00:00:00

abstract：:Increasing evidence suggests an association between gastrointestinal (GI) disorders and susceptibility and progress of Parkinson's disease (PD). Gut-brain axis has been proposed to play important roles in the pathogenesis of PD, though the exact pathophysiologic mechanism has yet to be elucidated. Here, we discuss the...

journal_title：Frontiers in neurology

authors： Chao YX,Gulam MY,Chia NSJ,Feng L,Rotzschke O,Tan EK

更新日期：2020-08-25 00:00:00

abstract：:To investigate the usefulness of pain-related evoked potentials (PREP) elicited by electrical stimulation for the identification of small fiber involvement in patients with mixed fiber neuropathy (MFN). Eleven MFN patients with clinical signs of large fiber impairment and neuropathic pain and ten healthy controls unde...

journal_title：Frontiers in neurology

authors： Hansen N,Kahn AK,Zeller D,Katsarava Z,Sommer C,Üçeyler N

更新日期：2015-12-07 00:00:00

abstract：:Background and aims: The pathophysiology of hippocampal enlarged perivascular spaces (H-EPVS) and its relationship to cognitive impairment is largely unknown. This study aimed to investigate the relationship between H-EPVS and cognition in non-dementic elderly population. Methods: A total of 109 subjects were prospect...

journal_title：Frontiers in neurology

authors： Sim JE,Park MS,Shin HY,Jang HS,Won HH,Seo SW,Seo WK,Kim BJ,Kim GM

更新日期：2020-09-29 00:00:00

abstract：:The developmental vulnerability of different classes of axonal pathways in preterm white matter is not known. We propose that laminar compartments of the developing cerebral wall serve as spatial framework for axonal growth and evaluate potential of anatomical landmarks for understanding reorganization of the cerebral...

journal_title：Frontiers in neurology

authors： Kostović I,Kostović-Srzentić M,Benjak V,Jovanov-Milošević N,Radoš M

更新日期：2014-07-29 00:00:00

abstract：:With the demographic shift of the global population toward longer life expectancy, the number of people living with Alzheimer's disease (AD) has rapidly expanded and is projected to triple by the year 2050. Current treatments provide symptomatic relief but do not affect the underlying pathology of the disease. Therapi...

journal_title：Frontiers in neurology

authors： Ritter A,Cummings J

更新日期：2015-08-31 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:This study presents the first implementation of functional ultrasound (fUS) imaging of the spinal cord to monitor local hemodynamic response to epidural electrical spinal cord stimulation (SCS) on two small and large animal models. SCS has been successfully applied to control chronic refractory pain and recently was e...

journal_title：Frontiers in neurology

authors： Song P,Cuellar CA,Tang S,Islam R,Wen H,Huang C,Manduca A,Trzasko JD,Knudsen BE,Lee KH,Chen S,Lavrov IA

更新日期：2019-03-26 00:00:00

abstract：:Surface electromyography (sEMG) is a widely used technology in rehabilitation research and provides quantifiable information on the myoelectric output of a muscle. In this perspective, we discuss the barriers which have restricted the wide-spread use of sEMG in clinical rehabilitation of individuals with spinal cord i...

journal_title：Frontiers in neurology

authors： Pilkar R,Momeni K,Ramanujam A,Ravi M,Garbarini E,Forrest GF

更新日期：2020-12-18 00:00:00

abstract：:Paraneoplastic autoimmune neurological disorders reflect tumor-initiated immune responses against onconeural antigens. Symptoms and signs can affect the central and/or peripheral nervous systems, neuromuscular junction or muscle, and typically evolve subacutely before an underlying neoplasm is discovered. We describe ...

journal_title：Frontiers in neurology

authors： Zhu M,Ma Y,Zekeridou A,Lennon VA

更新日期：2020-12-10 00:00:00

abstract：:Recent advances in wearable sensor technology and machine learning (ML) have allowed for the seamless and objective study of human motion in clinical applications, including Parkinson's disease, and stroke. Using ML to identify salient patterns in sensor data has the potential for widespread application in neurologica...

journal_title：Frontiers in neurology

authors： Parnandi A,Uddin J,Nilsen DM,Schambra HM

更新日期：2019-09-18 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:Penetrating brain trauma commonly results in occult neurovascular injury. Detailed cerebrovascular imaging can evaluate the relationship of intracranial foreign bodies to major vascular structures, assess for traumatic pseudoaneurysms, and ensure hemostasis during surgical removal. We report a case of a self-inflicted...

journal_title：Frontiers in neurology

authors： Rennert RC,Steinberg JA,Sack J,Pannell JS,Khalessi AA

更新日期：2016-07-14 00:00:00

abstract：:For epileptic patients requiring resective surgery, a modality called stereo-electroencephalography (SEEG) may be used to monitor the patient's brain signals to help identify epileptogenic regions that generate and propagate seizures. SEEG involves the insertion of multiple depth electrodes into the patient's brain, e...

journal_title：Frontiers in neurology

authors： Greene P,Li A,González-Martínez J,Sarma SV

更新日期：2021-01-06 00:00:00

abstract：:The cingulate island sign (CIS) on fludeoxyglucose (FDG)-positron emission tomography (PET) is a supporting biomarker of dementia with Lewy bodies (DLB). Its diagnostic accuracy has only been investigated in FDG-PET, however. The present prospective study compared the CIS on I-iodoamphetamine-single photon emission co...

journal_title：Frontiers in neurology

authors： Kanetaka H,Shimizu S,Inagawa Y,Hirose D,Takenoshita N,Sakurai H,Hanyu H

更新日期：2020-11-19 00:00:00

abstract：:Cerebral microbleeds (microbleeds) are small, punctuate hypointense lesions seen in T2* Gradient-Recall Echo (GRE) and Susceptibility-Weighted (SWI) Magnetic Resonance Imaging (MRI) sequences, corresponding to areas of hemosiderin breakdown products from prior microscopic hemorrhages. They occur in the setting of impa...

journal_title：Frontiers in neurology

authors： Yates PA,Villemagne VL,Ellis KA,Desmond PM,Masters CL,Rowe CC

更新日期：2014-01-06 00:00:00

abstract：:Introduction: Parkinson's disease (PD) is a neurodegenerative disorder affecting a substantial proportion of the elderly Cypriot population. The objective of this study was to evaluate PD risk variants that have been identified previously in Genome Wide Association Studies (GWAS) and to find environmental factors that...

journal_title：Frontiers in neurology

authors： Georgiou A,Demetriou CA,Christou YP,Heraclides A,Leonidou E,Loukaides P,Yiasoumi E,Pantziaris M,Kleopa KA,Papacostas SS,Loizidou MA,Hadjisavvas A,Zamba-Papanicolaou E

更新日期：2019-10-17 00:00:00

abstract：:To date, conflicting results about the role of vitamins in amyotrophic lateral sclerosis (ALS) have been reported along with a lack of systematic studies on all types of serum vitamins in patients with ALS. Moreover, extensive studies have been conducted on vitamins in other neurodegenerative diseases; however, whethe...

journal_title：Frontiers in neurology

authors： Wang M,Liu Z,Sun W,Yuan Y,Jiao B,Zhang X,Shen L,Jiang H,Xia K,Tang B,Wang J

更新日期：2020-06-18 00:00:00

abstract：:Preterm-born infants frequently suffer from an array of neurological damage, collectively termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting with a neurodevelopmental disorder (e.g., autism spectrum disorder; attention deficit hyperactivity disorder) later in life. It is hypothe...

journal_title：Frontiers in neurology

authors： Fleiss B,Gressens P,Stolp HB

更新日期：2020-07-14 00:00:00