Increased Circulating Exosomal miRNA-223 Is Associated with Acute Ischemic Stroke.

abstract：:Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation. Homeostasis of membrane sphingolipids in neurons and myelin is ess...

journal_title：Frontiers in neurology

authors： Alessenko AV,Albi E

更新日期：2020-05-21 00:00:00

abstract：:Inflammation after traumatic spinal cord injury (SCI) is non-resolving and thus still present in chronic injury stages. It plays a key role in the pathophysiology of SCI and has been associated with further neurodegeneration and development of neuropathic pain. Neural precursor cells (NPCs) have been shown to reduce t...

journal_title：Frontiers in neurology

authors： Riemann L,Younsi A,Scherer M,Zheng G,Skutella T,Unterberg AW,Zweckberger K

更新日期：2018-06-08 00:00:00

abstract：:Hyperbaric oxygen (HBO) therapy has been suggested a treatment option in order to reduce the development of secondary insults succeeding traumatic brain injury. This case report studied the course of a 23-year-old gentleman with a close range transhemispheric gunshot wound. The biochemical parameters, using a multi-mo...

journal_title：Frontiers in neurology

authors： Thelin EP,Bellander BM,Nekludov M

更新日期：2015-03-23 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:Mutations in both copies (homozygous or compound heterozygous) of the gene encoding the lysosomal enzyme glucocerebrosidase, which cleaves the glycolipid glucocerebroside into glucose and ceramide cause Gaucher disease. However, multiple independent studies have also reported an association between GBA mutations and P...

journal_title：Frontiers in neurology

authors： Almeida Mdo R

更新日期：2012-04-27 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：:Background: Prolonged static whole-body roll-tilt has been shown to bias estimates of the direction of gravity when assessed by static paradigms such as the subjective visual vertical and the subjective haptic vertical. Objective: We hypothesized that these shifts are paradigm-independent and thus predicted a post-til...

journal_title：Frontiers in neurology

authors： Wedtgrube A,Bockisch CJ,Straumann D,Tarnutzer AA

更新日期：2020-10-15 00:00:00

abstract：:Background: The leading cause of death in China is stroke, a condition that also contributes heavily to the disease burden. Nontraumatic intracerebral hemorrhage (ICH) is the second most common cause of stroke. Compared to Western countries, in China the proportion of ICH is significantly higher. Standardized treatmen...

journal_title：Frontiers in neurology

authors： Li D,Sun H,Ru X,Sun D,Guo X,Jiang B,Luo Y,Tao L,Fu J,Wang W

更新日期：2018-12-11 00:00:00

abstract：:The Boston Carpal Tunnel Questionnaire (BCTQ) is a scale that has been developed specifically for carpal tunnel syndrome (CTS). It consists of the Functional Status Scale (FSS) and the Symptom Severity Scale (SSS). It is the most widely used patient reported outcome measure in CTS and has been validated in many langua...

journal_title：Frontiers in neurology

authors： De Kleermaeker FGCM,Levels M,Verhagen WIM,Meulstee J

更新日期：2019-11-07 00:00:00

abstract：:Background: Microscopic polyangiitis (MPA) is a necrotizing vasculitis that affects predominantly small-sized vessels in many organ systems. The disease generally causes glomerulonephritis, pulmonary damage, arthritis, and neuropathy. An exclusive involvement of both central nervous system (CNS) and peripheral nervous...

journal_title：Frontiers in neurology

authors： Arienti F,Franco G,Monfrini E,Santaniello A,Bresolin N,Saetti MC,Di Fonzo A

更新日期：2020-04-28 00:00:00

abstract：:Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal muscle-initiated crosstalk with other tissues is accomplished though the secretion of myokines, protein hormones which can exert autoc...

journal_title：Frontiers in neurology

authors： Delezie J,Handschin C

更新日期：2018-08-24 00:00:00

abstract：:The corticospinal system is a major motor pathway in the control of skilled voluntary movements such as reaching and grasping. It has developed considerably phylogenetically to reach a peak in humans. Because rodents possess advanced forelimb movements that can be used for reaching and grasping food, it is commonly co...

journal_title：Frontiers in neurology

authors： Alstermark B,Pettersson LG

更新日期：2014-06-20 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to systematically review the efficacy and tolerability of gabapentin in the treatment of sleep disturbance in patients with medical illness. METHODS:PubMed was searched for randomized, double-blinded, placebo-controlled trials that reported sleep changes during gabapent...

journal_title：Frontiers in neurology

authors： Liu GJ,Karim MR,Xu LL,Wang SL,Yang C,Ding L,Wang YF

更新日期：2017-07-14 00:00:00

abstract：:Objective: We conducted this study to analyze the clinical characteristics of the psychiatric symptoms of patients with anti-NMDAR encephalitis. Methods: A retrospective study of anti-NMDAR encephalitis in China was performed. The clinical characteristics of the psychiatric symptoms, the relationship between the antib...

journal_title：Frontiers in neurology

authors： Wang W,Zhang L,Chi XS,He L,Zhou D,Li JM

更新日期：2020-01-24 00:00:00

abstract：:Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal stenosis and the hemodynamic significance of middle cerebral artery (MCA) steno...

journal_title：Frontiers in neurology

authors： Fang H,Leng X,Pu Y,Zou X,Pan Y,Song B,Soo YOY,Leung TWH,Wang C,Zhao X,Wang Y,Wang Y,Wong KS,Liu L,Xu Y,CICAS Study Group.

更新日期：2020-04-15 00:00:00

abstract：Background:It has been suggested that parkinsonian [Parkinson's disease (PD)] patients might have a "dominant" (DOM) subthalamic nucleus (STN), whose unilateral electrical stimulation [deep brain stimulation (DBS)] could lead to an improvement in PD symptoms similar to bilateral STN-DBS. Objectives:Since disability in...

journal_title：Frontiers in neurology

authors： Rizzone MG,Ferrarin M,Lanotte MM,Lopiano L,Carpinella I

更新日期：2017-10-30 00:00:00

abstract：:Background: Chronic subdural hematoma (cSDH) is a debilitating condition with a high rate of recurrence after surgical evacuation. Summary: This review is focused on middle meningeal artery (MMA) embolization to treat cSDH. We discuss the underlying pathophysiology of chronic subdural hematoma and how cessation of art...

journal_title：Frontiers in neurology

authors： Moshayedi P,Liebeskind DS

更新日期：2020-08-27 00:00:00

abstract：:Daith piercing is an ear piercing located at the crus of the helix, bilaterally. It is getting great consent on social media as alternative treatment in chronic migraine. No data about its efficacy and action are available in scientific literature so far. We present the case of a 54-year-old male patient suffering fro...

journal_title：Frontiers in neurology

authors： Cascio Rizzo A,Paolucci M,Altavilla R,Brunelli N,Assenza F,Altamura C,Vernieri F

更新日期：2017-11-27 00:00:00

abstract：:Localization of the epileptogenic zone (EZ) is crucial in the surgical treatment of focal epilepsy. Recently, EEG studies have revealed that the EZ exhibits abnormal connectivity, which has led investigators to now consider connectivity as a biomarker to localize the EZ. Further, abnormal connectivity of the EZ may pr...

journal_title：Frontiers in neurology

authors： Gupta K,Grover P,Abel TJ

更新日期：2020-11-25 00:00:00

abstract：BACKGROUND AND AIM:The availability and access of hospital administrative data [coding for Charlson comorbidity index (CCI)] in large data form has resulted in a surge of interest in using this information to predict mortality from stroke. The aims of this study were to determine the minimum clinical data set to be inc...

journal_title：Frontiers in neurology

authors： Phan TG,Clissold BB,Ma H,Ly JV,Srikanth V

更新日期：2017-05-19 00:00:00

abstract：:Numerous studies suggest that the increased activity of p38MAPK plays an important role in the abnormal immune and inflammatory response observed in the course of neurodegenerative diseases such as Alzheimer's disease. On the other hand, high levels of p38MAPK are present in the brain during normal aging, suggesting t...

journal_title：Frontiers in neurology

authors： Martín-Segura A,Casadomé-Perales Á,Fazzari P,Mas JM,Artigas L,Valls R,Nebreda AR,Dotti CG

更新日期：2019-06-25 00:00:00

abstract：:Penetrating brain trauma commonly results in occult neurovascular injury. Detailed cerebrovascular imaging can evaluate the relationship of intracranial foreign bodies to major vascular structures, assess for traumatic pseudoaneurysms, and ensure hemostasis during surgical removal. We report a case of a self-inflicted...

journal_title：Frontiers in neurology

authors： Rennert RC,Steinberg JA,Sack J,Pannell JS,Khalessi AA

更新日期：2016-07-14 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a disorder of the wrist due to narrowing of the carpal tunnel. It can be caused by trauma or tumors in the tunnel resulting in compression of the median nerve. This disorder is often diagnosed with early symptoms such as tingling, numbness, and weakness that subsequently lead to hand mu...

journal_title：Frontiers in neurology

authors： Emril DR,Zakaria I,Amrya M

更新日期：2019-08-26 00:00:00

abstract：OBJECTIVE:Morphological changes of recent small subcortical infarcts are not well defined. The purpose of the present study was to describe the MRI characteristics of the evolution for this stroke subtype. METHODS:We conducted a retrospective review of patients diagnosed with definite supratentorial recent small subco...

journal_title：Frontiers in neurology

authors： Okazaki S,Hornberger E,Griebe M,Gass A,Hennerici MG,Szabo K

更新日期：2015-05-26 00:00:00

abstract：:Intensive glycemic control has not shown consistent findings in stroke prevention for diabetes patients, particularly for those with microvascular complications. This case-control study evaluates the risks of stroke in Asian diabetic population with microvascular complications. From the insurance claims of Taiwan, we ...

journal_title：Frontiers in neurology

authors： Lo SF,Chen WL,Muo CH,Chen PC,Chen SY,Kuo CL,Sung FC

更新日期：2018-08-29 00:00:00

abstract：:This study aims to quantify passive muscle stiffness of spastic wrist flexors in stroke survivors using shear wave elastography (SWE) and to correlate with neural and non-neural contributors estimated from a biomechanical model to hyper-resistance measured during passive wrist extension. Fifteen hemiplegic individuals...

journal_title：Frontiers in neurology

authors： Leng Y,Wang Z,Bian R,Lo WLA,Xie X,Wang R,Huang D,Li L

更新日期：2019-07-10 00:00:00

abstract：:Objective: To determine whether performance in a virtual spatial navigational task is poorer in persistent postural perceptual dizziness (PPPD) patients than in healthy volunteers and patients suffering other vestibular disorders. Methods: Subjects were asked to perform three virtual Morris water maze spatial navigati...

journal_title：Frontiers in neurology

authors： Breinbauer HA,Contreras MD,Lira JP,Guevara C,Castillo L,Ruëdlinger K,Muñoz D,Delano PH

更新日期：2020-01-09 00:00:00

abstract：:We previously identified a distinct mutation pattern in the antibody genes of B cells isolated from cerebrospinal fluid (CSF) that can identify patients who have relapsing-remitting multiple sclerosis (RRMS) and patients with clinically isolated syndromes who will convert to RRMS. This antibody gene signature (AGS) wa...

journal_title：Frontiers in neurology

authors： Rounds WH,Ligocki AJ,Levin MK,Greenberg BM,Bigwood DW,Eastman EM,Cowell LG,Monson NL

更新日期：2014-09-16 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.00696.]. ...

journal_title：Frontiers in neurology

authors： Lin N,Hao H,Guan H,Sun H,Liu Q,Lu Q,Jin L,Ren H,Huang Y

更新日期：2020-10-30 00:00:00