Association Between Vitamins and Amyotrophic Lateral Sclerosis: A Center-Based Survey in Mainland China.

abstract：:Introduction: The recent publication of a trial failed to prove the efficacy of minimally invasive surgery (MIS) in patients with intracerebral hemorrhage. The aim of this study was to answer the question: Do we need more trials to compare MIS vs. conservative treatment in these patients? Methods: Databases were searc...

journal_title：Frontiers in neurology

authors： Zhou X,Xie L,Altinel Y,Qiao N

更新日期：2020-06-04 00:00:00

abstract：:Methamphetamine (METH) use, referred to as methamphetamine use disorder (MUD), results in neurocognitive decline, a characteristic shared with HIV-associated neurocognitive disorders (HAND). MUD exacerbates HAND partly through glutamate dysregulation. Astrocyte excitatory amino acid transporter (EAAT)-2 is responsible...

journal_title：Frontiers in neurology

authors： Cisneros IE,Ghorpade A,Borgmann K

更新日期：2020-11-25 00:00:00

abstract：:Background: Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease. The clinical manifestations of NIID are complex and easily misdiagnosed. Based on the current knowledge of this disease, it is usually chronic, with almost no acute cases. Stroke-like disease is an extremely rare type of NI...

journal_title：Frontiers in neurology

authors： Lin P,Jin H,Yi KC,He XS,Lin SF,Wu G,Zhang ZQ

更新日期：2020-06-10 00:00:00

abstract：INTRODUCTION:Options currently available to individuals with upper limb loss range from prosthetic hands that can perform many movements, but require more cognitive effort to control, to simpler terminal devices with limited functional abilities. We attempted to address this issue by designing a myoelectric control sys...

journal_title：Frontiers in neurology

authors： Gailey A,Artemiadis P,Santello M

更新日期：2017-02-01 00:00:00

abstract：:Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores exists. This study examined several possible composite scores for the test battery used in the large...

journal_title：Frontiers in neurology

authors： Stenberg J,Karr JE,Terry DP,Saksvik SB,Vik A,Skandsen T,Silverberg ND,Iverson GL

更新日期：2020-07-17 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.563609.]. ...

journal_title：Frontiers in neurology

authors： Zhang J,Meng Q,Zhong J,Zhang M,Qin X,Ni X,Ma J,He Y,Zeng D,Lan D

更新日期：2020-11-12 00:00:00

abstract：:Stroke is the second leading cause of death and physical disability, with a global lifetime incidence rate of 1 in 6. Currently, the only FDA approved treatment for ischemic stroke is the administration of tissue plasminogen activator (tPA). Stem cell clinical trials for stroke have been underway for close to two deca...

journal_title：Frontiers in neurology

authors： Krause M,Phan TG,Ma H,Sobey CG,Lim R

更新日期：2019-06-25 00:00:00

abstract：OBJECTIVE:Tinnitus is a common symptom of hearing impairment. Patients who are bilaterally hard of hearing are often affected by tinnitus. However, they cannot undergo any of the standard tinnitus therapies, since they rely on hearing. Cochlear implantation (CI) used to treat severe hearing disabilities, such as bilate...

journal_title：Frontiers in neurology

authors： Knopke S,Szczepek AJ,Häussler SM,Gräbel S,Olze H

更新日期：2017-04-25 00:00:00

abstract：:The purpose of the study was to test the utility of unique panel of blood biomarkers as a means to reflect one's recovery process after sport-related neurotrauma. We established a panel of biomarkers that reacted positive with CD81 (extracellular vesicle marker) and various neuron- and glia-specific antigens [e.g., ne...

journal_title：Frontiers in neurology

authors： Kawata K,Mitsuhashi M,Aldret R

更新日期：2018-04-12 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:α-synuclein is involved in the pathogenesis of multiple system atrophy (MSA) and can be regulated by peripheral immune activation (PIA). We aimed to clarify the correlations between PIA and the prevalence of MSA and to analyze the role of PIA in the progression of the disease. A total of 321 patients with probable MSA...

journal_title：Frontiers in neurology

authors： Cao B,Chen X,Zhang L,Wei Q,Liu H,Feng W,Chen Y,Shang H

更新日期：2020-07-07 00:00:00

abstract：:Shame and embarrassment related to Parkinson's disease (PD) are rarely addressed in clinical practice nor studied in neuroscience research, partly because no specific tool exists to detect them in PD. Objective: To develop a self-applied assessment tool of shame and embarrassment specifically related to PD or its trea...

journal_title：Frontiers in neurology

authors： Fleury V,Catalano Chiuvé S,Forjaz MJ,Di Marco M,Messe M,Debove I,Angulo J,Hariz GM,Burkhard PR,Martinez-Martin P,Rodriguez-Blazquez C,Krack P

更新日期：2020-07-31 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease which leads to death in a median time of 2-3 years. Inflammation has been claimed important to the ALS pathogenesis, but its role is still not well-characterized. In the present study, a panel of five cytokines (IL-2, IL-6, IL-10, IFN-gamma...

journal_title：Frontiers in neurology

authors： Tortelli R,Zecca C,Piccininni M,Benmahamed S,Dell'Abate MT,Barulli MR,Capozzo R,Battista P,Logroscino G

更新日期：2020-11-13 00:00:00

abstract：:Background: In people with multiple sclerosis (MS), optic neuritis (ON) results in inner retinal layer thinning, and reduced density of the retinal microvasculature. Objective: To compare inter-eye differences (IEDs) in macular optical coherence tomography (OCT) and OCT angiography (OCTA) measures in MS patients with ...

journal_title：Frontiers in neurology

authors： Murphy OC,Kalaitzidis G,Vasileiou E,Filippatou AG,Lambe J,Ehrhardt H,Pellegrini N,Sotirchos ES,Luciano NJ,Liu Y,Fitzgerald KC,Prince JL,Calabresi PA,Saidha S

更新日期：2020-12-15 00:00:00

abstract：:Background: Spinal and Bulbar Muscular Atrophy (SBMA) is caused by the extension of the polyglutamine tract within the androgen receptor (AR) gene, and results in a multisystem presentation, including the degeneration of lower motor neurons. The androgen receptor (AR) is known to modulate the expression of endogenous ...

journal_title：Frontiers in neurology

authors： Rex C,Nadeau MJ,Douville R,Schellenberg K

更新日期：2019-09-04 00:00:00

abstract：:A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thinking, fear and wor...

journal_title：Frontiers in neurology

authors： Naylor B,Hesam-Shariati N,McAuley JH,Boag S,Newton-John T,Rae CD,Gustin SM

更新日期：2019-12-03 00:00:00

abstract：:GNE myopathy is characterized by distal muscle weakness, and caused by recessive mutations in GNE. Its onset is characteristically in young adulthood, although a broad spectrum of onset age is known to exist. A large number of mutations in GNE are pathogenic and this clinical phenotype can be difficult to differentiat...

journal_title：Frontiers in neurology

authors： Soule T,Phan C,White C,Resch L,Lacson A,Martens K,Pfeffer G

更新日期：2018-11-08 00:00:00

abstract：:Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary brain damage. The underlying molecular and cellular cascades incorporate components of the innate immune system. There are different ...

journal_title：Frontiers in neurology

authors： Thelin EP,Tajsic T,Zeiler FA,Menon DK,Hutchinson PJA,Carpenter KLH,Morganti-Kossmann MC,Helmy A

更新日期：2017-07-20 00:00:00

abstract：:Skeletal muscle is an essential regulator of energy homeostasis and a potent coordinator of exercise-induced adaptations in other organs including the liver, fat or the brain. Skeletal muscle-initiated crosstalk with other tissues is accomplished though the secretion of myokines, protein hormones which can exert autoc...

journal_title：Frontiers in neurology

authors： Delezie J,Handschin C

更新日期：2018-08-24 00:00:00

abstract：:Botulinum NeuroToxin-A (BoNT-A) injections to the medial gastrocnemius (MG) and lower-leg casts are commonly combined to treat ankle equinus in children with spastic cerebral palsy (CP). However, the decomposed treatment effects on muscle or tendon structure, stretch reflexes, and joint are unknown. In this study, BoN...

journal_title：Frontiers in neurology

authors： Peeters N,Van Campenhout A,Hanssen B,Cenni F,Schless SH,Van den Broeck C,Desloovere K,Bar-On L

更新日期：2020-04-21 00:00:00

abstract：:Upright perception is a key aspect of orientation constancy, as we maintain a stable perception of the world despite continuous movements of our eyes, head, and body. Torsional position of the eyes can impact perception of upright by changing orientation of the images on the retina relative to gravity. Here, we invest...

journal_title：Frontiers in neurology

authors： Otero-Millan J,Winnick A,Kheradmand A

更新日期：2018-04-06 00:00:00

abstract：:Objectives: Elevated neurofilament light chain (NFL) levels within the cerebrospinal fluid (CSF) are a biomarker representing axonal neurodegeneration in rapid progressive neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). It is unclear to what extent the levels of NFL increase in the CSF (CSF-NFL...

journal_title：Frontiers in neurology

authors： Pawlitzki M,Schreiber S,Bittner D,Kreipe J,Leypoldt F,Rupprecht K,Carare RO,Meuth SG,Vielhaber S,Körtvélyessy P

更新日期：2018-12-14 00:00:00

abstract：:Hereditary spastic paraplegias (HSPs) are a heterogeneous group of genetic disorders with spastic paraparesis as the main clinical feature. Complex forms may co-occur with other motor, sensory, and cognitive impairment. A growing number of loci and genes are being identified, but still more than 50% of the patients re...

journal_title：Frontiers in neurology

authors： Aguilera-Albesa S,de la Hoz AB,Ibarluzea N,Ordóñez-Castillo AR,Busto-Crespo O,Villate O,Ibiricu-Yanguas MA,Yoldi-Petri ME,García de Gurtubay I,Perez de Nanclares G,Pereda A,Tejada MI

更新日期：2020-02-14 00:00:00

abstract：:Background: Trigeminal neuralgia (TN) is a recognized pain condition the treatment of which can be very challenging. Various surgical interventions can be applied in cases of therapy-resistance to drug treatments. The central lateral thalamotomy (CLT) against neurogenic (or neuropathic) pain is based on multiarchitect...

journal_title：Frontiers in neurology

authors： Gallay MN,Moser D,Jeanmonod D

更新日期：2020-04-17 00:00:00

abstract：:The most frequent neurodegenerative diseases (NDs) are Alzheimer's disease (AD), Parkinson's disease (PD), and frontotemporal lobar degeneration associated with protein TDP-43 (FTLD-TDP). Neuropathologically, NDs are characterized by abnormal intracellular and extra-cellular protein deposits and by disease-specific ne...

journal_title：Frontiers in neurology

authors： Grinberg LT,Rueb U,Heinsen H

更新日期：2011-07-11 00:00:00

abstract：:Attention impairment may provide a cohesive neurobiological explanation for clusters of clinical symptoms that occur after a concussion; therefore, objective quantification of attention is needed. Visually tracking a moving target is an attention-dependent sensorimotor function, and eye movement can be recorded easily...

journal_title：Frontiers in neurology

authors： Maruta J,Spielman LA,Rajashekar U,Ghajar J

更新日期：2018-07-26 00:00:00

abstract：:Background: Ischemic stroke patients show alterations in peripheral leukocyte counts that may result from the sterile inflammation response as well as the occurrence of early infections. We here aimed to determine whether alterations of circulating leukocytes in acute ischemic stroke are associated with long-term func...

journal_title：Frontiers in neurology

authors： Semerano A,Strambo D,Martino G,Comi G,Filippi M,Roveri L,Bacigaluppi M

更新日期：2020-04-03 00:00:00

abstract：OBJECTIVE:Effective stroke care does not end with acute treatment during hospitalization, but extends through rehabilitation and secondary stroke prevention. In transitions across care environments, stroke patients are vulnerable to errors in communication of diagnosis and treatment. This study aimed to demonstrate tha...

journal_title：Frontiers in neurology

authors： Hill CE,Varma P,Lenrow D,Price RS,Kasner SE

更新日期：2015-10-27 00:00:00

abstract：BACKGROUND:Sudden unexpected death in epilepsy (SUDEP) is common among young people with epilepsy. Individuals who are at high risk of SUDEP exhibit regional brain structural and functional connectivity (FC) alterations compared with low-risk patients. However, less is known about network-based FC differences among cri...

journal_title：Frontiers in neurology

authors： Allen LA,Harper RM,Kumar R,Guye M,Ogren JA,Lhatoo SD,Lemieux L,Scott CA,Vos SB,Rani S,Diehl B

更新日期：2017-10-16 00:00:00

abstract：:Background: Patients with traumatic brain injury (TBI) exhibit a variable and unpredictable outcome. The proteins interleukin 10 (IL-10) and heart fatty acid-binding protein (H-FABP) have shown predictive values for the presence of intracranial lesions. Aim: To evaluate the individual and combined outcome prediction a...

journal_title：Frontiers in neurology

authors： Lagerstedt L,Azurmendi L,Tenovuo O,Katila AJ,Takala RSK,Blennow K,Newcombe VFJ,Maanpää HR,Tallus J,Hossain I,van Gils M,Menon DK,Hutchinson PJ,Zetterberg H,Posti JP,Sanchez JC

更新日期：2020-06-02 00:00:00