Fasting versus post-challenge triglycerides and pre-existing cavitating lacunes: a berlin "cream & sugar" substudy.

abstract：:Spinal muscular atrophy (SMA) is a severe neuromuscular disorder characterized by the degeneration of motor neurons in the spinal cord, and comprises a broad clinical spectrum. With the advent of new therapies (e.g., Nusinersen) for patients of all ages and disease stages, sensitive clinical measures are needed to det...

journal_title：Frontiers in neurology

authors： Kruse T,Lehmann HC,Braumann B,Fink GR,Wunderlich G

更新日期：2020-02-25 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:Robust and reliable stroke lesion segmentation is a crucial step toward employing lesion volume as an independent endpoint for randomized trials. The aim of this work was to develop and evaluate a novel method to segment sub-acute ischemic stroke lesions from fluid-attenuated inversion recovery (FLAIR) magnetic resona...

journal_title：Frontiers in neurology

authors： Subbanna NK,Rajashekar D,Cheng B,Thomalla G,Fiehler J,Arbel T,Forkert ND

更新日期：2019-05-24 00:00:00

abstract：:Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysphagia during early postnatal life in the LgDel mouse model of 22q11DS ...

journal_title：Frontiers in neurology

authors： Welby L,Caudill H,Yitsege G,Hamad A,Bunyak F,Zohn IE,Maynard T,LaMantia AS,Mendelowitz D,Lever TE

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:Before implementation in clinical practice, biomarker assays need to be thoroughly analytically validated. There is currently a strong interest in implementation of the ratio of amyloid-β peptide 1-42 and 1-40 (Aβ42/Aβ40) in clinical routine. Therefore, in this study, we compared the analytical performance o...

journal_title：Frontiers in neurology

authors： van Waalwijk van Doorn LJC,Kulic L,Koel-Simmelink MJA,Kuiperij HB,Versleijen AAM,Struyfs H,Twaalfhoven HAM,Fourier A,Engelborghs S,Perret-Liaudet A,Lehmann S,Verbeek MM,Vanmechelen EJM,Teunissen CE

更新日期：2017-07-03 00:00:00

abstract：:Objective: The peak-to-peak amplitude of the p13-n23 wave in cervical vestibular evoked myogenic potential can increase after furosemide administration in patients with Meniere's disease [furosemide-loading VEMP (FVEMP) testing]. The examination is used to test for the presence of endolymphatic hydrops; we investigate...

journal_title：Frontiers in neurology

authors： Seo T,Shiraishi K,Kobayashi T,Fujita T,Saito K,Doi K

更新日期：2018-08-03 00:00:00

abstract：:Despite extensive research, the functions of the basal ganglia (BG) in movement control have not been fully understood. Eye movements, particularly saccades, are convenient indicators of BG function. Here, we review the main oculomotor findings reported in Parkinson's disease (PD) and genetic parkinsonian syndromes. P...

journal_title：Frontiers in neurology

authors： Pretegiani E,Optican LM

更新日期：2017-11-09 00:00:00

abstract：AIMS:To construct and validate a short scale for the assessment of the severity of visual height intolerance (vHI) and acrophobia. METHODS:The questionnaire was developed from two earlier representative epidemiological studies (n = 5,529). Items were applied in a telephone survey of a representative population-based s...

journal_title：Frontiers in neurology

authors： Huppert D,Grill E,Brandt T

更新日期：2017-06-01 00:00:00

abstract：:Objectives: Enlarged perivascular spaces in the basal ganglia (BG-EPVS) share common vascular risk factors with atherosclerosis. However, little is known about the relationship between steno-occlusive middle cerebral artery (MCA) and BG-EPVS. In this cross-sectional study, we aimed to test the hypothesis that severe M...

journal_title：Frontiers in neurology

authors： Du H,Chen C,Ye C,Lin F,Wei J,Xia P,Chen R,Wu S,Yuan Q,Chen H,Xiao Y,Liu N

更新日期：2020-04-23 00:00:00

abstract：:Background: Glioblastoma (GBM) is the most aggressive type of primary malignant brain tumor. Carmustine is used by intravenous injection or local implantation in the resection cavity for gliomas, including GBMs. However, the therapeutic potential of carmustine is not well-recognized. This analysis aimed to evaluate th...

journal_title：Frontiers in neurology

authors： Xiao ZZ,Wang ZF,Lan T,Huang WH,Zhao YH,Ma C,Li ZQ

更新日期：2020-09-17 00:00:00

abstract：:Purpose: Stroke-associated pneumonia (SAP), a common complication in acute ischemic stroke (AIS) patients, is associated with poor prognosis after AIS. Inflammation plays an important role in the development of SAP. In this study, we aimed to explore the association between the monocyte-to-lymphocyte ratio (MLR) and S...

journal_title：Frontiers in neurology

authors： Cheng HR,Song JY,Zhang YN,Chen YB,Lin GQ,Huang GQ,He JC,Wang Z

更新日期：2020-10-06 00:00:00

abstract：:Humans evolved a symbiotic relationship with their gut microbiome, a complex microbial community composed of bacteria, archaea, protists, and viruses, including bacteriophages. The enteric nervous system (ENS) is a gateway for the bidirectional communication between the brain and the gut, mostly through the vagus nerv...

journal_title：Frontiers in neurology

authors： Santos SF,de Oliveira HL,Yamada ES,Neves BC,Pereira A Jr

更新日期：2019-06-04 00:00:00

abstract：:Tadpole pupil is a rare phenomenon in which segmental spasm of the iris dilator muscle results in a tadpole-shaped pupil. The pupillary distortion is usually unilateral, lasts several minutes, and can recur in clusters. Any segment of the iris can be affected; thus, for some patients, a different-shaped tadpole pupil ...

journal_title：Frontiers in neurology

authors： Udry M,Kardon RH,Sadun F,Kawasaki A

更新日期：2019-08-19 00:00:00

abstract：Objective:The aim of this study was to detect the key changes during sit-to-stand (STS) movement cycle in hemiparetic stroke survivors using a five-phase kinematic and kinetic analysis. Methods:Twenty-five subacute stroke survivors and 17 age-matched healthy adults participated in this study. The kinematic and kinetic...

journal_title：Frontiers in neurology

authors： Mao YR,Wu XQ,Zhao JL,Lo WLA,Chen L,Ding MH,Xu ZQ,Bian RH,Huang DF,Li L

更新日期：2018-03-26 00:00:00

abstract：:Magnetic resonance imaging (MRI) is a non-destructive technique that is capable of localizing pathologies and assessing other anatomical features (e.g., tissue volume, microstructure, and white matter connectivity) in postmortem, ex vivo human brains. However, when brains are removed from the skull and cerebrospinal f...

journal_title：Frontiers in neurology

authors： Shatil AS,Matsuda KM,Figley CR

更新日期：2016-11-29 00:00:00

abstract：:Object: Predicting whether intramedullary slitlike cavity (SC) will worsen over time or remain stable is an outstanding clinical challenge. The aim of this study was to identify early features of SC (clinical and magnetic resonance imaging [MRI] findings). Methods: We prospectively included all patients referred to ou...

journal_title：Frontiers in neurology

authors： Faillot M,Morar S,Delphine S,El-Mendili M,Ducreux D,Parker F,Aghakhani N

更新日期：2020-06-12 00:00:00

abstract：:Daith piercing is an ear piercing located at the crus of the helix, bilaterally. It is getting great consent on social media as alternative treatment in chronic migraine. No data about its efficacy and action are available in scientific literature so far. We present the case of a 54-year-old male patient suffering fro...

journal_title：Frontiers in neurology

authors： Cascio Rizzo A,Paolucci M,Altavilla R,Brunelli N,Assenza F,Altamura C,Vernieri F

更新日期：2017-11-27 00:00:00

abstract：:Wireless transmission of cortical signals is an essential step to improve the safety of epilepsy procedures requiring seizure focus localization and to provide chronic recording of brain activity for Brain Computer Interface (BCI) applications. Our group developed a fully implantable and externally rechargeable device...

journal_title：Frontiers in neurology

authors： Piangerelli M,Ciavarro M,Paris A,Marchetti S,Cristiani P,Puttilli C,Torres N,Benabid AL,Romanelli P

更新日期：2014-08-25 00:00:00

abstract：OBJECTIVE:Evaluate medical students' communication and professionalism skills from the perspective of the ambulatory patient and later compare these skills in their first year of residency. METHODS:Students in third year neurology clerkship clinics see patients alone followed by a revisit with an attending neurologist...

journal_title：Frontiers in neurology

authors： Davis LE,King MK,Wayne SJ,Kalishman SG

更新日期：2012-06-20 00:00:00

abstract：:Introduction: It remains unclear if tau imaging may assist diagnosis of chronic traumatic encephalopathy (CTE). Flortaucipir PET has shown superior frontal with medial temporal tau binding consistent with the provisional neuropathological criteria for mid-stage CTE in group-level analyses of retired symptomatic NFL pl...

journal_title：Frontiers in neurology

authors： Krishnadas N,Doré V,Lamb F,Groot C,McCrory P,Guzman R,Mulligan R,Huang K,O'Donnell M,Ponsford J,Hopwood M,Villemagne VL,Rowe CC

更新日期：2020-12-22 00:00:00

abstract：:Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

journal_title：Frontiers in neurology

authors： Lu H,Wu PF,Li RZ,Zhang W,Huang GX

更新日期：2020-10-07 00:00:00

abstract：:Carpal tunnel syndrome (CTS) is a disorder of the wrist due to narrowing of the carpal tunnel. It can be caused by trauma or tumors in the tunnel resulting in compression of the median nerve. This disorder is often diagnosed with early symptoms such as tingling, numbness, and weakness that subsequently lead to hand mu...

journal_title：Frontiers in neurology

authors： Emril DR,Zakaria I,Amrya M

更新日期：2019-08-26 00:00:00

abstract：:Huntington's Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive, and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to the rate of striata...

journal_title：Frontiers in neurology

authors： Moumné L,Betuing S,Caboche J

更新日期：2013-10-23 00:00:00

abstract：BACKGROUND:Amnestic mild cognitive impairment (aMCI) is considered to be the transitional stage between healthy aging and Alzheimer's disease (AD). Moreover, aMCI individuals with additional impairment in one or more non-memory cognitive domains are at higher risk of conversion to AD. Hence accurate identification of t...

journal_title：Frontiers in neurology

authors： Raamana PR,Wen W,Kochan NA,Brodaty H,Sachdev PS,Wang L,Beg MF

更新日期：2014-05-21 00:00:00

abstract：:Background: Automated ASPECTS has the potential of reducing interobserver variability in the determination of early ischemic changes. We aimed to assess the performance of an automated ASPECTS vs. ASPECTS interpreted for sent CT images on WhatsApp and to correlate these results with the outcome. Materials and Methods:...

journal_title：Frontiers in neurology

authors： Mansour OY,Ramadan I,Abdo A,Hamdi M,Eldeeb H,Marouf H,Elsalamawy D,Elfatatry A,Elnekidy A,Reda MI

更新日期：2020-05-19 00:00:00

abstract：OBJECTIVE:(1) To determine the brain connectivity pattern associated with clinical rigidity scores in Parkinson's disease (PD) and (2) to determine the relation between clinically assessed rigidity and quantitative metrics of motor performance. BACKGROUND:Rigidity, the resistance to passive movement, is exacerbated in...

journal_title：Frontiers in neurology

authors： Baradaran N,Tan SN,Liu A,Ashoori A,Palmer SJ,Wang ZJ,Oishi MM,McKeown MJ

更新日期：2013-06-05 00:00:00

abstract：:Objective: Episodic memory is frequently impaired in Multiple Sclerosis (MS), but the cognitive characteristics and neuropsychological processes involved remain controversial. Our aim was to study episodic memory dysfunction in MS, using the LASSI-L, a novel memory-based cognitive stress test that uses a new paradigm ...

journal_title：Frontiers in neurology

authors： Matias-Guiu JA,Cortés-Martínez A,Curiel RE,Delgado-Álvarez A,Fernández-Oliveira A,Pytel V,Montero P,Moreno-Ramos T,Loewenstein DA,Matías-Guiu J

更新日期：2020-04-21 00:00:00

abstract：OBJECTIVE:The vestibular implant seems feasible as a clinically useful device in the near future. However, hearing preservation during intralabyrinthine implantation remains a challenge. It should be preserved to be able to treat patients with bilateral vestibulopathy and (partially) intact hearing. This case study inv...

journal_title：Frontiers in neurology

authors： van de Berg R,Lucieer F,Guinand N,van Tongeren J,George E,Guyot JP,Kingma H,van Hoof M,Temel Y,van Overbeeke J,Perez-Fornos A,Stokroos R

更新日期：2017-04-10 00:00:00

abstract：:Significant advances have been made in the understanding of the numerous mechanisms involved in Parkinson's disease (PD) pathogenesis. The identification of PD pathogenic mutations and the use of different animal models have contributed to better elucidate the processes underlying the disease. Here, we report a brief ...

journal_title：Frontiers in neurology

authors： Imbriani P,Schirinzi T,Meringolo M,Mercuri NB,Pisani A

更新日期：2018-03-01 00:00:00

abstract：:Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are kno...

journal_title：Frontiers in neurology

authors： Hirokawa Y,Fujimoto A,Ichikawa N,Sato K,Tanaka T,Enoki H,Otsuki Y,Okanishi T

更新日期：2019-06-12 00:00:00