Money Management in Multiple Sclerosis: The Role of Cognitive, Motor, and Affective Factors.

abstract：Background:There is increasing interest in stem cell therapy as another treatment modality in stroke, particularly for patients who are unable to receive endovascular clot retrieval or thrombolysis therapies, or for whom standard treatment has failed. We have recently shown that human amniotic epithelial cells (hAECs) ...

journal_title：Frontiers in neurology

authors： Phan TG,Ma H,Lim R,Sobey CG,Wallace EM

更新日期：2018-06-07 00:00:00

abstract：:Multiple sclerosis (MS) is a neurodegenerative disease characterized by lesions in the central nervous system (CNS). Inflammation and demyelination are the leading causes of neuronal death and brain lesions formation. The immune reactivity is believed to be essential in the neuronal damage in MS. Cytokines play import...

journal_title：Frontiers in neurology

authors： Goyal M,Khanna D,Rana PS,Khaibullin T,Martynova E,Rizvanov AA,Khaiboullina SF,Baranwal M

更新日期：2019-07-18 00:00:00

abstract：:Despite the advent of and exciting advances in novel endovascular therapies, t-PA remains the only proven treatment for acute ischemic stroke to date. Although a variety of reasons likely underlie why past trials of endovascular strategies have been unsuccessful, we address in this perspective piece one critical unkno...

journal_title：Frontiers in neurology

authors： Tansy AP,Liebeskind DS

更新日期：2013-10-21 00:00:00

abstract：OBJECTIVE:To provide a systematic review of the clinical and radiological features of lesion-induced central positional nystagmus (CPN) and identify salient characteristics that differentiate central from peripheral positional nystagmus (PN). METHODS:Systematic literature search according to the preferred reporting it...

journal_title：Frontiers in neurology

authors： Macdonald NK,Kaski D,Saman Y,Al-Shaikh Sulaiman A,Anwer A,Bamiou DE

更新日期：2017-04-20 00:00:00

abstract：:Background: Matrix metalloproteinases (MMPs) are pleiotropic enzymes involved in extracellular protein degradation and turnover. MMPs are implicated in the pathogenesis of many neurological diseases, including multiple sclerosis (MS). Objective: To search the level of MMPs in the cerebrospinal fluid (CSF) of MS patien...

journal_title：Frontiers in neurology

authors： Castellazzi M,Ligi D,Contaldi E,Quartana D,Fonderico M,Borgatti L,Bellini T,Trentini A,Granieri E,Fainardi E,Mannello F,Pugliatti M

更新日期：2018-12-18 00:00:00

abstract：:Disorders of the central nervous system sometimes cause severe sensory motor paralysis accompanied by gait impairment. Recently, there are several reports on the effectiveness of robot-assisted gait training for patients experiencing these issues. The purpose of this case report was to assess the neuromechanical effec...

journal_title：Frontiers in neurology

authors： Kadone H,Kubota S,Abe T,Noguchi H,Miura K,Koda M,Shimizu Y,Hada Y,Sankai Y,Suzuki K,Yamazaki M

更新日期：2020-03-31 00:00:00

abstract：:Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term ...

journal_title：Frontiers in neurology

authors： Zhang R,Liu G,Jiang Y,Li G,Pan Y,Wang Y,Wei Z,Wang J,Wang Y

更新日期：2018-10-02 00:00:00

abstract：:Background and objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic arteriopathy, the classic feature of which is small vessel lesions. Studies on intracranial large arteries in CADASIL are not common. We aim to evaluate intracranial l...

journal_title：Frontiers in neurology

authors： Zhang C,Li W,Li S,Niu S,Wang X,Yu X,Zhang Z

更新日期：2020-08-18 00:00:00

abstract：:Over the last two decades, many experimental and clinical studies have provided solid evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to Parkinson's disease (PD) pathology. To provide an overview on the different roles of this protein, here we propose a synopsis of seminal...

journal_title：Frontiers in neurology

authors： Ghiglieri V,Calabrese V,Calabresi P

更新日期：2018-05-04 00:00:00

abstract：:Botulinum NeuroToxin-A (BoNT-A) injections to the medial gastrocnemius (MG) and lower-leg casts are commonly combined to treat ankle equinus in children with spastic cerebral palsy (CP). However, the decomposed treatment effects on muscle or tendon structure, stretch reflexes, and joint are unknown. In this study, BoN...

journal_title：Frontiers in neurology

authors： Peeters N,Van Campenhout A,Hanssen B,Cenni F,Schless SH,Van den Broeck C,Desloovere K,Bar-On L

更新日期：2020-04-21 00:00:00

abstract：:Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression. Polycomb group (PcG) proteins are master controllers of gene silencin...

journal_title：Frontiers in neurology

authors： Reynolds JP,Miller-Delaney SF,Jimenez-Mateos EM,Sano T,McKiernan RC,Simon RP,Henshall DC

更新日期：2015-03-10 00:00:00

abstract：:Background and Purpose: The relationship between cerebral microbleeds (CMBs) and prognosis in patients with ischemic stroke is still unclear. Our aim here was to verify the relationship between CMBs and functional outcomes in patients with minor ischemic stroke treated with antiplatelet therapy. Methods: We retrospect...

journal_title：Frontiers in neurology

authors： Sakuta K,Yaguchi H,Sato T,Komatsu T,Sakai K,Mitsumura H,Matsushima S,Iguchi Y

更新日期：2020-06-16 00:00:00

abstract：:Attention impairment may provide a cohesive neurobiological explanation for clusters of clinical symptoms that occur after a concussion; therefore, objective quantification of attention is needed. Visually tracking a moving target is an attention-dependent sensorimotor function, and eye movement can be recorded easily...

journal_title：Frontiers in neurology

authors： Maruta J,Spielman LA,Rajashekar U,Ghajar J

更新日期：2018-07-26 00:00:00

abstract：:Many neurodegenerative disorders are associated with rapid eye movement sleep (REMS) loss; however, the mechanism was unknown. As REMS loss elevates noradrenaline (NA) level in the brain as well as induces neuronal apoptosis and degeneration, in this study, we have delineated the intracellular molecular pathway involv...

journal_title：Frontiers in neurology

authors： Somarajan BI,Khanday MA,Mallick BN

更新日期：2016-03-07 00:00:00

abstract：:Background: The sequence effect (SE), referring to step-to-step reduction in amplitude, is considered to lead to freezing of gait (FOG) in Parkinson's disease (PD). Visual cues may alleviate SE and help reduce freezing episodes. FOG patients show significant SE prior to turning or toward a doorway, but the SE toward a...

journal_title：Frontiers in neurology

authors： Cao SS,Yuan XZ,Wang SH,Taximaimaiti R,Wang XP

更新日期：2020-08-12 00:00:00

abstract：:Migraine is a chronic disease characterized by unilateral, pulsating, and often moderate-to-severe recurrent episodes of headache with nausea and vomiting. It affects approximately 15% of the general population, yet the underlying pathophysiological mechanisms are not fully understood. Optical coherence tomography (OC...

journal_title：Frontiers in neurology

authors： Ascaso FJ,Marco S,Mateo J,Martínez M,Esteban O,Grzybowski A

更新日期：2017-12-13 00:00:00

abstract：:Myotonic dystrophy type 1 (DM1) is an autosomal dominant genetic disease characterized by multi-system involvement. Affected organ system includes skeletal muscle, heart, gastro-intestinal system and the brain. In this review, we evaluate the evidence for alterations in insulin signaling and their relation to clinical...

journal_title：Frontiers in neurology

authors： Nieuwenhuis S,Okkersen K,Widomska J,Blom P,'t Hoen PAC,van Engelen B,Glennon JC

更新日期：2019-11-26 00:00:00

abstract：:Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) are neurodegenerative diseases with characteristic inflammatory demyelination in the central nervous system, including the optic nerve. Neuronal and axonal damage is considered to be the main cause of long-term disability in p...

journal_title：Frontiers in neurology

authors： Quinn TA,Dutt M,Shindler KS

更新日期：2011-08-02 00:00:00

abstract：:To date, conflicting results about the role of vitamins in amyotrophic lateral sclerosis (ALS) have been reported along with a lack of systematic studies on all types of serum vitamins in patients with ALS. Moreover, extensive studies have been conducted on vitamins in other neurodegenerative diseases; however, whethe...

journal_title：Frontiers in neurology

authors： Wang M,Liu Z,Sun W,Yuan Y,Jiao B,Zhang X,Shen L,Jiang H,Xia K,Tang B,Wang J

更新日期：2020-06-18 00:00:00

abstract：:Objectives: Patient-reported outcomes gain importance for the assessment of auditory abilities in cochlear implant users and for the evaluation of auditory rehabilitation. Aims of the study were to explore the interrelation of self-reported improvements in auditory ability with improvements in speech comprehension and...

journal_title：Frontiers in neurology

authors： Wallhäusser-Franke E,Balkenhol T,Hetjens S,Rotter N,Servais JJ

更新日期：2018-09-10 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:There is currently no therapeutic drug treatment for traumatic brain injury (TBI) despite decades of experimental clinical trials. This may be because the mechanistic pathways for improving TBI outcomes have yet to be identified and exploited. As such, there remains a need to seek out new molecular targets and their d...

journal_title：Frontiers in neurology

authors： Hook G,Jacobsen JS,Grabstein K,Kindy M,Hook V

更新日期：2015-09-02 00:00:00

abstract：:Cranioplasty (CP) after decompressive craniectomy (DC) for trauma is a neurosurgical procedure that aims to restore esthesis, improve cerebrospinal fluid (CSF) dynamics, and provide cerebral protection. In turn, this can facilitate neurological rehabilitation and potentially enhance neurological recovery. However, CP ...

journal_title：Frontiers in neurology

authors： Iaccarino C,Kolias AG,Roumy LG,Fountas K,Adeleye AO

更新日期：2020-01-29 00:00:00

abstract：:We describe three patients diagnosed with bilateral vestibular dysfunction associated with the jet propellant type-eight (JP-8) fuel exposure. Chronic exposure to aromatic and aliphatic hydrocarbons, which are the main constituents of JP-8 military aircraft jet fuel, occurred over 3-5 years' duration while working on ...

journal_title：Frontiers in neurology

authors： Fife TD,Robb MJA,Steenerson KK,Saha KC

更新日期：2018-05-16 00:00:00

abstract：:Background and aims: The pathophysiology of hippocampal enlarged perivascular spaces (H-EPVS) and its relationship to cognitive impairment is largely unknown. This study aimed to investigate the relationship between H-EPVS and cognition in non-dementic elderly population. Methods: A total of 109 subjects were prospect...

journal_title：Frontiers in neurology

authors： Sim JE,Park MS,Shin HY,Jang HS,Won HH,Seo SW,Seo WK,Kim BJ,Kim GM

更新日期：2020-09-29 00:00:00

abstract：:Background: Automated ASPECTS has the potential of reducing interobserver variability in the determination of early ischemic changes. We aimed to assess the performance of an automated ASPECTS vs. ASPECTS interpreted for sent CT images on WhatsApp and to correlate these results with the outcome. Materials and Methods:...

journal_title：Frontiers in neurology

authors： Mansour OY,Ramadan I,Abdo A,Hamdi M,Eldeeb H,Marouf H,Elsalamawy D,Elfatatry A,Elnekidy A,Reda MI

更新日期：2020-05-19 00:00:00

abstract：:Glaucoma damages retinal ganglion cells, including intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells modulate various non-visual physiological and psychological functions which are modulated by light. In patients with glaucoma, we assessed the effect of daily bright light exposure (LE) on sever...

journal_title：Frontiers in neurology

authors： Kawasaki A,Udry M,El Wardani M,Münch M

更新日期：2021-01-15 00:00:00

abstract：:Background: Increasing evidence indicates that early radiation-induced subtle cerebral changes may be the precursors to permanent brain dysfunction at the late-delayed (LDS) post-radiotherapy (RT) stage. In this study, we aim to track the RT-related longitudinal brain activity in nasopharyngeal carcinoma (NPC) patient...

journal_title：Frontiers in neurology

authors： Yang Y,Lin X,Li J,Han L,Li Z,Liu S,Hou G,Xie C,Lv X,Qiu Y

更新日期：2019-07-16 00:00:00

abstract：:Glycogenosis VII (GSD VII) is a rare autosomal recessive glycogen storage disorder caused by mutations in the PFKM gene encoding the phosphofructokinase (PFK) enzyme. A classical form with exercise intolerance, contractures, and myoglobinuria, a severe multisystem infantile form, an hemolytic variant and a late-onset ...

journal_title：Frontiers in neurology

authors： Filosto M,Cotti Piccinelli S,Pichiecchio A,Musumeci O,Galvagni A,Caria F,Gallo Cassarino S,Baldelli E,Vitale R,Padovani A,Toscano A

更新日期：2019-02-07 00:00:00

abstract：:This chapter overviews research neuroimaging findings of patients with medication-overuse headache (MOH). Results indicate; (i) correlations between neuropathology and medication-overuse; (ii) changes in brain morphology and cortical function; and (iii) brain recovery subsequent to withdrawal of medication that was ov...

journal_title：Frontiers in neurology

authors： Chong CD

更新日期：2020-01-28 00:00:00