MMP-9-Related microRNAs as Prognostic Markers for Hemorrhagic Transformation in Cardioembolic Stroke Patients.

abstract：:Objective: The objective of this study was to investigate the roles and mechanisms of inflammatory mediators NLRP3 and IL-1β in refractory temporal epilepsy brain injury. Method: First, the brain tissue and the peripheral blood of children undergoing intractable temporal lobe epilepsy surgery were analyzed as research...

journal_title：Frontiers in neurology

authors： Wu C,Zhang G,Chen L,Kim S,Yu J,Hu G,Chen J,Huang Y,Zheng G,Huang S

更新日期：2020-02-07 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercis...

journal_title：Frontiers in neurology

authors： Paré MF,Jasmin BJ

更新日期：2017-09-27 00:00:00

abstract：:Antiphospholipid syndrome (APS) is an autoimmune antibody-mediated condition characterized by thrombotic events and/or pregnancy morbidity in association with persistent positivity to antiphospholipid antibodies (aPL). The nervous system is frequently affected, as intracranial vessels are the most frequent site of art...

journal_title：Frontiers in neurology

authors： Fleetwood T,Cantello R,Comi C

更新日期：2018-11-26 00:00:00

abstract：:Neuropathological features in Alzheimer's disease (AD) are amyloid β (Aβ) deposits and neurofibrillary changes. AD is characterized by memory impairment and cognitive dysfunction, with some reports associating these impairments with hyperexcitability caused by Aβ in the medial temporal lobe. Epileptic seizures are kno...

journal_title：Frontiers in neurology

authors： Hirokawa Y,Fujimoto A,Ichikawa N,Sato K,Tanaka T,Enoki H,Otsuki Y,Okanishi T

更新日期：2019-06-12 00:00:00

abstract：:This study aimed to assess the efficacy and safety of self-designed Ningxin Anshen (NXAS) Formula for post-ischemic stroke insomnia of blood-deficient and liver-heat syndrome. Ninety patients were randomized into NXAS group, Placebo group and Zopiclone group. Patients in the NXAS group, Placebo group and Zopiclone gro...

journal_title：Frontiers in neurology

authors： Dai N,Li Y,Sun J,Li F,Xiong H

更新日期：2020-11-09 00:00:00

abstract：:Traumatic brain injury (TBI) is a major cause of death worldwide. Depending on the severity of the injury, TBI can reflect a broad range of consequences such as speech impairment, memory disturbances, and premature death. In this study, embryonic neural stem cells (ENSC) were isolated from E14 mouse embryos and cultur...

journal_title：Frontiers in neurology

authors： Nasser M,Ballout N,Mantash S,Bejjani F,Najdi F,Ramadan N,Soueid J,Zibara K,Kobeissy F

更新日期：2018-10-24 00:00:00

abstract：:Adolescents with traumatic brain injury (TBI) typically demonstrate good recovery of previously acquired skills. However, higher-order and later emergent cognitive functions are often impaired and linked to poor outcomes in academic and social/behavioral domains. Few control trials exist that test cognitive treatment ...

journal_title：Frontiers in neurology

authors： Cook LG,Chapman SB,Elliott AC,Evenson NN,Vinton K

更新日期：2014-06-11 00:00:00

abstract：OBJECTIVE:The vestibular implant seems feasible as a clinically useful device in the near future. However, hearing preservation during intralabyrinthine implantation remains a challenge. It should be preserved to be able to treat patients with bilateral vestibulopathy and (partially) intact hearing. This case study inv...

journal_title：Frontiers in neurology

authors： van de Berg R,Lucieer F,Guinand N,van Tongeren J,George E,Guyot JP,Kingma H,van Hoof M,Temel Y,van Overbeeke J,Perez-Fornos A,Stokroos R

更新日期：2017-04-10 00:00:00

abstract：:Narcolepsy with cataplexy is a rare, but important differential diagnosis for daytime sleepiness and atonic paroxysms in an adolescent. A recent increase in incidence in the pediatric age group probably linked to the use of the Pandemrix influenza vaccine in 2009, has increased awareness that different environmental f...

journal_title：Frontiers in neurology

authors： Rosch RE,Farquhar M,Gringras P,Pal DK

更新日期：2016-08-10 00:00:00

abstract：:Objective: To determine whether performance in a virtual spatial navigational task is poorer in persistent postural perceptual dizziness (PPPD) patients than in healthy volunteers and patients suffering other vestibular disorders. Methods: Subjects were asked to perform three virtual Morris water maze spatial navigati...

journal_title：Frontiers in neurology

authors： Breinbauer HA,Contreras MD,Lira JP,Guevara C,Castillo L,Ruëdlinger K,Muñoz D,Delano PH

更新日期：2020-01-09 00:00:00

abstract：:Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes. It has been argued that discovery of disease-relevant biomarkers might help to guide successful clinical trials for TBI. Major advances in mass spectrome...

journal_title：Frontiers in neurology

authors： Guingab-Cagmat JD,Cagmat EB,Hayes RL,Anagli J

更新日期：2013-05-31 00:00:00

abstract：:Background and Purpose: This study aimed to investigate the efficacy of cerebrospinal fluid shunt intervention for idiopathic normal pressure hydrocephalus (iNPH) using data from a nationwide epidemiological survey in Japan. Methods: We conducted a cross-sectional study using data from a nationwide epidemiological sur...

journal_title：Frontiers in neurology

authors： Nakajima M,Miyajima M,Ogino I,Akiba C,Kawamura K,Kurosawa M,Kuriyama N,Watanabe Y,Fukushima W,Mori E,Kato T,Sugano H,Karagiozov K,Arai H

更新日期：2018-06-07 00:00:00

abstract：:Background: This study aims to investigate the association between blood pressure (BP) at the time of recanalization and hemorrhagic transformation in large vessel occlusion (LVO) patients following mechanical thrombectomy (MT) with general anesthesia. Methods: We retrospectively reviewed our data base for patients wi...

journal_title：Frontiers in neurology

authors： Cheng H,Xu C,Jin X,Chen Y,Zheng X,Shi F,He X,Hao Y,Jiang Y,Zhang J,Chen Z

更新日期：2020-11-17 00:00:00

abstract：:Traumatic brain injury (TBI) is understood as an interplay between the initial injury, subsequent secondary injuries, and a complex host response all of which are highly heterogeneous. An understanding of the underlying biology suggests a number of windows where mechanistically inspired interventions could be targeted...

journal_title：Frontiers in neurology

authors： Ercole A,Magnoni S,Vegliante G,Pastorelli R,Surmacki J,Bohndiek SE,Zanier ER

更新日期：2017-08-30 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2018.00662.]. ...

journal_title：Frontiers in neurology

authors： Agahi A,Hamidi GA,Daneshvar R,Hamdieh M,Soheili M,Alinaghipour A,Taba SME,Salami M

更新日期：2019-02-05 00:00:00

abstract：:Traumatic brain injury (TBI) and the activation of secondary injury mechanisms have been linked to impaired cognitive function, which, as observed in TBI patients and animal models, can persist for months and years following the initial injury. Impairments in neurotransmission have been well documented in experimental...

journal_title：Frontiers in neurology

authors： Carlson SW,Henchir J,Dixon CE

更新日期：2017-10-10 00:00:00

abstract：:This review begins with the history of the events starting with the death of Libby Zion that lead to the Bell Commission, that the studied her death and made recommendations for improvement that were codified into law in New York state as the 405 law that the ACGME essentially adopted in putting a cap on work hours an...

journal_title：Frontiers in neurology

authors： Kramer M

更新日期：2010-10-20 00:00:00

abstract：:Multiple sclerosis (MS) is a neurodegenerative disease characterized by lesions in the central nervous system (CNS). Inflammation and demyelination are the leading causes of neuronal death and brain lesions formation. The immune reactivity is believed to be essential in the neuronal damage in MS. Cytokines play import...

journal_title：Frontiers in neurology

authors： Goyal M,Khanna D,Rana PS,Khaibullin T,Martynova E,Rizvanov AA,Khaiboullina SF,Baranwal M

更新日期：2019-07-18 00:00:00

abstract：:Despite the clinical significance of post-stroke angiogenesis, a detailed phenotypic analysis of pre-stroke vascular remodeling and post-stroke angiogenesis had not yet been done in a model of focal ischemia. In this study, using BrdU-labeling of proliferating cells and immunofluorescence of pre- and post-stroke rats,...

journal_title：Frontiers in neurology

authors： Surugiu R,Glavan D,Popescu M,Margaritescu O,Eugen R,Popa-Wagner A

更新日期：2018-11-27 00:00:00

abstract：:Background: Little is known about sleep and circadian rhythms in survivors of acute respiratory failure (ARF) after hospital discharge. Objectives: To examine sleep and rest-activity circadian rhythms in ARF survivors 3 months after hospital discharge, and to compare them with a community-dwelling population. Methods:...

journal_title：Frontiers in neurology

authors： Yang PL,Ward TM,Burr RL,Kapur VK,McCurry SM,Vitiello MV,Hough CL,Parsons EC

更新日期：2020-02-14 00:00:00

abstract：:Functional connectivity maps using resting-state functional magnetic resonance imaging (rs-fMRI) can closely resemble task fMRI activation patterns, suggesting that resting-state brain activity may predict task-evoked activation or behavioral performance. However, this conclusion was mostly drawn upon a healthy popula...

journal_title：Frontiers in neurology

authors： Hu J,Du J,Xu Q,Yang F,Zeng F,Dai XJ,Liu X,Lu G,Zhang Z

更新日期：2017-07-19 00:00:00

abstract：:Background: Agoraphobia was described in 1871 as a condition of fear-related alterations in spatial orientation and locomotor control triggered by places or situations that might cause a patient to panic and feel trapped. In contemporary nosology, however, this original concept of agoraphobia was split into two diagno...

journal_title：Frontiers in neurology

authors： Indovina I,Conti A,Lacquaniti F,Staab JP,Passamonti L,Toschi N

更新日期：2019-08-13 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disorder characterized by loss of dopamine neurons. Since a seminal report was published in the early twentieth century, a growing body of literature has suggested that patients with PD display characteristic personality traits, such as cautiousness and inflexibil...

journal_title：Frontiers in neurology

authors： Abe N,Kawasaki I,Hosokawa H,Baba T,Takeda A

更新日期：2018-05-24 00:00:00

abstract：:Introduction: Stroke rehabilitation should start early in order to optimize patients' outcomes, but most trials include subacute or chronic patients. Although suggested that early stroke rehabilitation trials face difficulties regarding patient recruitment with corresponding low recruitment rates, no systematically co...

journal_title：Frontiers in neurology

authors： Held JPO,van Duinen J,Luft AR,Veerbeek JM

更新日期：2019-07-02 00:00:00

abstract：:Background: Subthalamic nucleus deep brain stimulation (STN-DBS) has been an established method in improvement of motor disabilities in Parkinson's disease (PD) patients. It has been also claimed to have an impact on balance and gait disorders in PD patients, but the previous results are conflicting. Objective: The ai...

journal_title：Frontiers in neurology

authors： Szlufik S,Kloda M,Friedman A,Potrzebowska I,Gregier K,Mandat T,Przybyszewski A,Dutkiewicz J,Figura M,Habela P,Koziorowski D

更新日期：2018-10-31 00:00:00

abstract：:Background and Purpose: Acute intracerebral hemorrhage (ICH) requires rapid decision making toward neurosurgery or conservative neurological stroke unit treatment. In a previous study, we found overestimation of clinical symptoms when clinicians rely mainly on cerebral computed tomography (cCT) analysis. The current s...

journal_title：Frontiers in neurology

authors： Wagner A,Schebesch KM,Isenmann S,Steinbrecher A,Kapapa T,Zeman F,Baldaranov D,Grauer O,Backhaus R,Linker RA,Schlachetzki F

更新日期：2019-09-26 00:00:00

abstract：:Impulse control disorder (ICD) is a major non-motor complication of Parkinson's disease (PD) with often devastating consequences for patients' quality of life. In this study, we aimed to characterize the phenotype of impulsivity in PD and its neuroanatomical correlates. Methods: Thirty-seven PD patients (15 patients w...

journal_title：Frontiers in neurology

authors： Hlavatá P,Linhartová P,Šumec R,Filip P,Světlák M,Baláž M,Kašpárek T,Bareš M

更新日期：2020-01-10 00:00:00

abstract：:Sudden infant death syndrome (SIDS) is the unexplained death, usually during sleep, of a baby younger than 1-year-old. Even though researchers have discovered some factors that may put babies at extra risk, SIDS remains unpredictable up until now. One hypothesis is that impaired cardiovascular control may play a role ...

journal_title：Frontiers in neurology

authors： Zhao F,Li M,Jiang Z,Tsien JZ,Lu Z

更新日期：2016-12-23 00:00:00

abstract：:Background:Candida dubliniensis is closely related to Candida albicans and rarely isolated in clinical specimens. C. dubliniensis is increasingly recognized as a pathogen in immunocompromised hosts. We present the third known case of Candida dubliniensis meningitis in a young immunocompetent host. Case Presentation: A...

journal_title：Frontiers in neurology

authors： Tahir M,Peseski AM,Jordan SJ

更新日期：2020-12-08 00:00:00

abstract：:Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs that mediate many relevant non-image forming functions of the eye, including the pupillary light reflex, through the projections to the olivary pretectal nucleus. In particular, the post-illumination pupil response (PIPR), as evaluated by ...

journal_title：Frontiers in neurology

authors： La Morgia C,Carelli V,Carbonelli M

更新日期：2018-12-07 00:00:00