Sleep and Circadian Rhythms in Survivors of Acute Respiratory Failure.

Abstract:

:Background: Little is known about sleep and circadian rhythms in survivors of acute respiratory failure (ARF) after hospital discharge. Objectives: To examine sleep and rest-activity circadian rhythms in ARF survivors 3 months after hospital discharge, and to compare them with a community-dwelling population. Methods: Sleep diary, actigraphy data, and insomnia symptoms were collected in a pilot study of 14 ARF survivors. Rest-activity circadian rhythms were assessed with wrist actigraphy and sleep diary for 9 days, and were analyzed by cosinor and non-parametric circadian rhythm analysis. Results: All participants had remarkable actigraphic sleep fragmentation, 71.5% had subclinical or clinical insomnia symptoms. Compared to community-dwelling adults, this cohort had less stable rest-activity circadian rhythms (p < 0.001), and weaker circadian strength (p < 0.001). Conclusion: Insomnia and circadian disruption were common in ARF survivors. Sleep improvement and circadian rhythm regularity may be a promising approach to improve quality of life and daytime function after ARF.

journal_name

Front Neurol

journal_title

Frontiers in neurology

authors

Yang PL,Ward TM,Burr RL,Kapur VK,McCurry SM,Vitiello MV,Hough CL,Parsons EC

doi

10.3389/fneur.2020.00094

subject

Has Abstract

pub_date

2020-02-14 00:00:00

pages

94

issn

1664-2295

journal_volume

11

pub_type

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