Corrigendum: Does Severity of Alzheimer's Disease Contribute to Its Responsiveness to Modifying Gut Microbiota? A Double Blind Clinical Trial.


:[This corrects the article DOI: 10.3389/fneur.2018.00662.].


Front Neurol


Frontiers in neurology


Agahi A,Hamidi GA,Daneshvar R,Hamdieh M,Soheili M,Alinaghipour A,Taba SME,Salami M




Has Abstract


2019-02-05 00:00:00








  • Immunohistochemical Analysis of Brainstem Lesions in the Autopsy Cases with Severe Motor and Intellectual Disabilities Showing Sudden Unexplained Death.

    abstract::It is known that patients with severe motor and intellectual disabilities (SMID) showed sudden unexplained death (SUD), in which autopsy failed to identify causes of death. Although the involvement of brainstem dysfunction is speculated, the detailed neuropathological analysis still remains to be performed. In order t...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Hayashi M,Sakuma H

    更新日期:2016-06-27 00:00:00

  • Mobility Deficits Assessed With Mobile Technology: What Can We Learn From Brain Iron-Altered Animal Models?

    abstract::Background: Recent developments in mobile technology have enabled the investigation of human movements and mobility under natural conditions, i.e., in the home environment. Iron accumulation in the basal ganglia is deleterious in Parkinson's disease (i.e., iron accumulation with lower striatal level of dopamine). The ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审


    authors: Hopfner F,Hobert MA,Maetzler C,Hansen C,Pham MH,Moreau C,Berg D,Devos D,Maetzler W,Fair-Park II study group.

    更新日期:2019-08-08 00:00:00

  • Memory Impairment in Relapsing-Remitting Multiple Sclerosis Using a Challenging Semantic Interference Task.

    abstract::Objective: Episodic memory is frequently impaired in Multiple Sclerosis (MS), but the cognitive characteristics and neuropsychological processes involved remain controversial. Our aim was to study episodic memory dysfunction in MS, using the LASSI-L, a novel memory-based cognitive stress test that uses a new paradigm ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Matias-Guiu JA,Cortés-Martínez A,Curiel RE,Delgado-Álvarez A,Fernández-Oliveira A,Pytel V,Montero P,Moreno-Ramos T,Loewenstein DA,Matías-Guiu J

    更新日期:2020-04-21 00:00:00

  • Middle Meningeal Artery Embolization in Chronic Subdural Hematoma: Implications of Pathophysiology in Trial Design.

    abstract::Background: Chronic subdural hematoma (cSDH) is a debilitating condition with a high rate of recurrence after surgical evacuation. Summary: This review is focused on middle meningeal artery (MMA) embolization to treat cSDH. We discuss the underlying pathophysiology of chronic subdural hematoma and how cessation of art...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审


    authors: Moshayedi P,Liebeskind DS

    更新日期:2020-08-27 00:00:00

  • Disparities in Functional Outcome After Intracerebral Hemorrhage Among Asians and Pacific Islanders.

    abstract:Background:Disparities in outcome after intracerebral hemorrhage (ICH) among Asians, Native Hawaiians, and other Pacific Islanders (NHOPI) have been inadequately studied. We sought to assess differences in functional outcome between Asians and NHOPI after ICH. Methods:A multiracial prospective cohort study of ICH pati...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Nakagawa K,King SL,Seto TB,Mau MKLM

    更新日期:2018-03-27 00:00:00

  • ISLES 2016 and 2017-Benchmarking Ischemic Stroke Lesion Outcome Prediction Based on Multispectral MRI.

    abstract::Performance of models highly depend not only on the used algorithm but also the data set it was applied to. This makes the comparison of newly developed tools to previously published approaches difficult. Either researchers need to implement others' algorithms first, to establish an adequate benchmark on their data, o...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Winzeck S,Hakim A,McKinley R,Pinto JAADSR,Alves V,Silva C,Pisov M,Krivov E,Belyaev M,Monteiro M,Oliveira A,Choi Y,Paik MC,Kwon Y,Lee H,Kim BJ,Won JH,Islam M,Ren H,Robben D,Suetens P,Gong E,Niu Y,Xu J,Pauly

    更新日期:2018-09-13 00:00:00

  • Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis.

    abstract::Background and Purpose: Internal carotid artery stenosis (ICAS)≥70% is a leading cause of ischemic cerebrovascular events (ICVEs). However, a considerable percentage of stroke survivors with symptomatic ICAS (sICAS) have <70% stenosis with a vulnerable plaque. Whether the length of ICAS is associated with high risk of...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Elhfnawy AM,Heuschmann PU,Pham M,Volkmann J,Fluri F

    更新日期:2019-04-09 00:00:00

  • Parkinson's disease rigidity: relation to brain connectivity and motor performance.

    abstract:OBJECTIVE:(1) To determine the brain connectivity pattern associated with clinical rigidity scores in Parkinson's disease (PD) and (2) to determine the relation between clinically assessed rigidity and quantitative metrics of motor performance. BACKGROUND:Rigidity, the resistance to passive movement, is exacerbated in...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Baradaran N,Tan SN,Liu A,Ashoori A,Palmer SJ,Wang ZJ,Oishi MM,McKeown MJ

    更新日期:2013-06-05 00:00:00

  • Spontaneous behavior in noise and silence: a possible new measure to assess tinnitus in Guinea pigs.

    abstract::This study describes two experiments that were conducted in search for a behavioral paradigm to test for tinnitus in guinea pigs. Conditioning paradigms are available to determine the presence of tinnitus in animals and are based on the assumption that tinnitus impairs their ability to detect silent intervals in conti...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Heeringa AN,Agterberg MJ,van Dijk P

    更新日期:2014-10-15 00:00:00

  • Treadmill training improves overground walking economy in Parkinson's disease: a randomized, controlled pilot study.

    abstract::Gait disturbances are one of the principal and most incapacitating symptoms of Parkinson's disease (PD). In addition, walking economy is impaired in PD patients and could contribute to excess fatigue in this population. An important number of studies have shown that treadmill training can improve kinematic parameters ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Fernández-Del-Olmo MA,Sanchez JA,Bello O,Lopez-Alonso V,Márquez G,Morenilla L,Castro X,Giraldez M,Santos-García D

    更新日期:2014-09-26 00:00:00

  • Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients.

    abstract::Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in t...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Almendros I,Martínez-García MÁ,Campos-Rodríguez F,Riveiro-Falkenbach E,Rodríguez-Peralto JL,Nagore E,Martorell-Calatayud A,Hernández Blasco L,Bañuls Roca J,Chiner Vives E,Sánchez-de-la-Torre A,Abad-Capa J,Montserrat JM,Pérez-Gi

    更新日期:2018-04-26 00:00:00

  • Informed consent: the rate-limiting step in acute stroke trials.

    abstract::Successful implementation of a randomized clinical trial (RCT) for neuro-vascular emergencies such as cerebral infarction, intracerebral hemorrhage, or subarachnoid hemorrhage is extraordinarily challenging. Besides establishing an accurate, hyper-expedited diagnosis among many mimics in a person with acute neurologic...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Rose DZ,Kasner SE

    更新日期:2011-10-17 00:00:00

  • Meta-analysis of Vascular Imaging Features to Predict Outcome Following Intravenous rtPA for Acute Ischemic Stroke.

    abstract:BACKGROUND:The present review investigated which findings in vascular imaging techniques can be used to predict clinical outcome and the risk of symptomatic intracerebral hemorrhage (sICH) in patients who underwent intravenous thrombolytic treatment. METHODS:Publications were searched, and the inclusion criteria were ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审


    authors: Nogueira RC,Bor-Seng-Shu E,Saeed NP,Teixeira MJ,Panerai RB,Robinson TG

    更新日期:2016-05-18 00:00:00

  • The Diagnostic Scope of Sensor-Based Gait Analysis in Atypical Parkinsonism: Further Observations.

    abstract::Background: Differentiating idiopathic Parkinson's disease (IPD) from atypical Parkinsonian disorders (APD) is challenging, especially in early disease stages. Postural instability and gait difficulty (PIGD) are substantial motor impairments of IPD and APD. Clinical evidence implies that patients with APD have larger ...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Gaßner H,Raccagni C,Eskofier BM,Klucken J,Wenning GK

    更新日期:2019-01-22 00:00:00

  • Prevalence of Vestibular Disorder in Older People Who Experience Dizziness.

    abstract::Dizziness and imbalance are clinically poorly defined terms, which affect ~30% of people over 65 years of age. In these people, it is often difficult to define the primary cause of dizziness, as it can stem from cardiovascular, vestibular, psychological, and neuromuscular causes. However, identification of the primary...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Chau AT,Menant JC,Hübner PP,Lord SR,Migliaccio AA

    更新日期:2015-12-24 00:00:00

  • Subtypes of Alzheimer's Disease Display Distinct Network Abnormalities Extending Beyond Their Pattern of Brain Atrophy.

    abstract::Different subtypes of Alzheimer's disease (AD) with characteristic distributions of neurofibrillary tangles and corresponding brain atrophy patterns have been identified using structural magnetic resonance imaging (MRI). However, the underlying biological mechanisms that determine this differential expression of neuro...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Ferreira D,Pereira JB,Volpe G,Westman E

    更新日期:2019-05-28 00:00:00

  • Quality of Life in Newly Diagnosed Patients With Parkin-Related Parkinson's Disease.

    abstract::Introduction: Mutations in the Parkin gene are the most common cause of autosomal recessive early-onset Parkinson's disease (PD). However, little is known about the quality of life (QoL) in Parkin-related PD. Here, we investigated the patterns of QoL in newly diagnosed Parkin-related PD patients. Methods: Newly diagno...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Zhou XY,Liu FT,Chen C,Luo SS,Zhao J,Tang YL,Shen B,Yu WB,Zuo CT,Wu JJ,Ding ZT,Wang J,Sun YM

    更新日期:2020-12-18 00:00:00

  • Rate and Determinants of Recurrence at 1 Year and 5 Years After Stroke in a Low-Income Population in Rural China.

    abstract::Recurrent stroke is becoming an increasingly important public health issue owing to the increased risk of disability and death. However, population-based studies investigating the rate of recurrent stroke in China are rare. We explored the rate and determinants of recurrent stroke within 1 and 5 years after the initia...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Han J,Mao W,Ni J,Wu Y,Liu J,Bai L,Shi M,Tu J,Ning X,Wang J

    更新日期:2020-01-23 00:00:00

  • Ocular Tremor in Parkinson's Disease: Discussion, Debate, and Controversy.

    abstract::The identification of ocular tremor in a small cohort of patients with Parkinson's disease (PD) had lay somewhat dormant until the recent report of a pervasive ocular tremor as a universal finding in a large PD cohort that was, however, generally absent from a cohort of age-matched healthy subjects. The reported tremo...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审


    authors: Kaski D,Bronstein AM

    更新日期:2017-04-24 00:00:00

  • Stepping to the Beat: Feasibility and Potential Efficacy of a Home-Based Auditory-Cued Step Training Program in Chronic Stroke.

    abstract:BACKGROUND:Hemiparesis after stroke typically results in a reduced walking speed, an asymmetrical gait pattern and a reduced ability to make gait adjustments. The purpose of this pilot study was to investigate the feasibility and preliminary efficacy of home-based training involving auditory cueing of stepping in place...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Wright RL,Brownless SB,Pratt D,Sackley CM,Wing AM

    更新日期:2017-08-22 00:00:00

  • An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function.

    abstract::Severe mercury intoxication is very rare in developed countries, but still occurs as the result of volatile substance abuse, suicide attempts, occupational hazards, or endemic food ingestion as reported in the cases of public health disasters in Iraq and in Minamata Bay, Japan. Here, we describe the dramatic physical ...

    journal_title:Frontiers in neurology



    authors: Kleffner I,Eichler S,Ruck T,Schüngel L,Pfeuffer S,Polzer P,Dittrich R,Dziewas R,Gross CC,Göbel K,Wiendl H,Kehrel BE,Meuth SG

    更新日期:2017-09-28 00:00:00

  • Sleep Duration and Stroke: A Mendelian Randomization Study.

    abstract::Study Objectives: To clarify the effects of sleep duration on stroke and stroke subtypes, we adopted a Mendelian randomization (MR) approach to evaluate their causal relationship. Methods: A genome-wide association study including 446,118 participants from UK biobank was used to identify instruments for short sleep, l...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Lu H,Wu PF,Li RZ,Zhang W,Huang GX

    更新日期:2020-10-07 00:00:00

  • Transverse Strips Instead of Wearable Laser Lights Alleviate the Sequence Effect Toward a Destination in Parkinson's Disease Patients With Freezing of Gait.

    abstract::Background: The sequence effect (SE), referring to step-to-step reduction in amplitude, is considered to lead to freezing of gait (FOG) in Parkinson's disease (PD). Visual cues may alleviate SE and help reduce freezing episodes. FOG patients show significant SE prior to turning or toward a doorway, but the SE toward a...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Cao SS,Yuan XZ,Wang SH,Taximaimaiti R,Wang XP

    更新日期:2020-08-12 00:00:00

  • Fluid Biomarkers in Clinical Trials of Alzheimer's Disease Therapeutics.

    abstract::With the demographic shift of the global population toward longer life expectancy, the number of people living with Alzheimer's disease (AD) has rapidly expanded and is projected to triple by the year 2050. Current treatments provide symptomatic relief but do not affect the underlying pathology of the disease. Therapi...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章,评审


    authors: Ritter A,Cummings J

    更新日期:2015-08-31 00:00:00

  • Early Detection of Hypothermic Neuroprotection Using T2-Weighted Magnetic Resonance Imaging in a Mouse Model of Hypoxic Ischemic Encephalopathy.

    abstract::Perinatal hypoxic-ischemic encephalopathy (HIE) can lead to neurodevelopmental disorders, including cerebral palsy. Standard care for neonatal HIE includes therapeutic hypothermia, which provides partial neuroprotection; magnetic resonance imaging (MRI) is often used to assess injury and predict outcome after HIE. Imm...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Doman SE,Girish A,Nemeth CL,Drummond GT,Carr P,Garcia MS,Johnston MV,Kannan S,Fatemi A,Zhang J,Wilson MA

    更新日期:2018-05-08 00:00:00

  • Damage in the Thalamocortical Tracts is Associated With Subsequent Thalamus Atrophy in Early Multiple Sclerosis.

    abstract::Background: In early multiple sclerosis (MS), thalamus atrophy and decreased integrity of the thalamocortical white matter (WM) tracts have been observed. Objective: To investigate the temporal association between thalamus volume and WM damage in the thalamocortical tract in subjects with early MS. Methods: At two tim...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Weeda MM,Pruis IJ,Westerveld ASR,Brouwer I,Bellenberg B,Barkhof F,Vrenken H,Lukas C,Schneider R,Pouwels PJW

    更新日期:2020-11-17 00:00:00

  • Early-Onset Parkinson's Disease Caused by PLA2G6 Compound Heterozygous Mutation, a Case Report and Literature Review.

    abstract::PLA2G6 has been certified as a causative gene in patients with autosomal recessive early-onset Parkinson's disease (EOPD). We reported an EOPD case caused by PLA2G6 gene mutation, and performed neurological examination, genetic analysis, and multimodal neuroimaging to describe this phenotype. A compound heterozygous m...

    journal_title:Frontiers in neurology



    authors: Shen T,Hu J,Jiang Y,Zhao S,Lin C,Yin X,Yan Y,Pu J,Lai HY,Zhang B

    更新日期:2019-08-21 00:00:00

  • Association Between Steno-Occlusive Middle Cerebral Artery and Basal Ganglia Perivascular Spaces.

    abstract::Objectives: Enlarged perivascular spaces in the basal ganglia (BG-EPVS) share common vascular risk factors with atherosclerosis. However, little is known about the relationship between steno-occlusive middle cerebral artery (MCA) and BG-EPVS. In this cross-sectional study, we aimed to test the hypothesis that severe M...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Du H,Chen C,Ye C,Lin F,Wei J,Xia P,Chen R,Wu S,Yuan Q,Chen H,Xiao Y,Liu N

    更新日期:2020-04-23 00:00:00

  • Changes in Neuronal Excitability by Activated Microglia: Differential Na(+) Current Upregulation in Pyramid-Shaped and Bipolar Neurons by TNF-α and IL-18.

    abstract::Microglia are activated during pathological events in the brain and are capable of releasing various types of inflammatory cytokines. Here, we demonstrate that the addition of 5% microglia activated by 1 μg/ml lipopolysaccharides (LPS) to hippocampal cultures upregulates Na(+) current densities (INavD) of bipolar as w...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Klapal L,Igelhorst BA,Dietzel-Meyer ID

    更新日期:2016-03-30 00:00:00

  • Access to End-of Life Parkinson's Disease Patients Through Patient-Centered Integrated Healthcare.

    abstract::Background: Palliative care in Parkinson's Disease (PD) patients considerably differs from palliative care in oncology patients. Integrated care models are a concept to support patients and improve management of PD symptoms. However, it is not known if the access to PD patients at the end of life can be achieved throu...

    journal_title:Frontiers in neurology

    pub_type: 杂志文章


    authors: Eggers C,Dano R,Schill J,Fink GR,Timmermann L,Voltz R,Golla H,Lorenzl S

    更新日期:2018-07-30 00:00:00