Presence of Multiple Autoimmune Antibodies Involved in Concurrent Myositis and Myocarditis and Myasthenia Gravis Without Thymoma: A Case Report.

abstract：:Manual dexterity measures can be useful for early detection of age-related functional decline and for prediction of cognitive decline. However, what aspects of sensorimotor function to assess remains unclear. Manual dexterity markers should be able to separate impairments related to cognitive decline from those relate...

journal_title：Frontiers in neurology

authors： Carment L,Abdellatif A,Lafuente-Lafuente C,Pariel S,Maier MA,Belmin J,Lindberg PG

更新日期：2018-10-29 00:00:00

abstract：:Children and adolescent athletes are at a higher risk for concussion than adults, and also experience longer recovery times and increased associated symptoms. It has also recently been demonstrated that multiple, seemingly mild concussions may result in exacerbated and prolonged neurological deficits. Objective assess...

journal_title：Frontiers in neurology

authors： Kiefer AW,Barber Foss K,Reches A,Gadd B,Gordon M,Rushford K,Laufer I,Weiss M,Myer GD

更新日期：2015-11-20 00:00:00

abstract：:Introduction: Parkinson's disease (PD) is a neurodegenerative disorder affecting a substantial proportion of the elderly Cypriot population. The objective of this study was to evaluate PD risk variants that have been identified previously in Genome Wide Association Studies (GWAS) and to find environmental factors that...

journal_title：Frontiers in neurology

authors： Georgiou A,Demetriou CA,Christou YP,Heraclides A,Leonidou E,Loukaides P,Yiasoumi E,Pantziaris M,Kleopa KA,Papacostas SS,Loizidou MA,Hadjisavvas A,Zamba-Papanicolaou E

更新日期：2019-10-17 00:00:00

abstract：:Tadpole pupil is a rare phenomenon in which segmental spasm of the iris dilator muscle results in a tadpole-shaped pupil. The pupillary distortion is usually unilateral, lasts several minutes, and can recur in clusters. Any segment of the iris can be affected; thus, for some patients, a different-shaped tadpole pupil ...

journal_title：Frontiers in neurology

authors： Udry M,Kardon RH,Sadun F,Kawasaki A

更新日期：2019-08-19 00:00:00

abstract：:We previously identified a distinct mutation pattern in the antibody genes of B cells isolated from cerebrospinal fluid (CSF) that can identify patients who have relapsing-remitting multiple sclerosis (RRMS) and patients with clinically isolated syndromes who will convert to RRMS. This antibody gene signature (AGS) wa...

journal_title：Frontiers in neurology

authors： Rounds WH,Ligocki AJ,Levin MK,Greenberg BM,Bigwood DW,Eastman EM,Cowell LG,Monson NL

更新日期：2014-09-16 00:00:00

abstract：:Aims: To examine trajectories of employment probability up to 10 years following moderate-to-severe traumatic brain injury (TBI) and identify significant predictors from baseline socio-demographic and injury characteristics. Methods: A longitudinal observational study followed 97 individuals with moderate-to-severe TB...

journal_title：Frontiers in neurology

authors： Howe EI,Andelic N,Perrin PB,Røe C,Sigurdardottir S,Arango-Lasprilla JC,Lu J,Løvstad M,Forslund MV

更新日期：2018-12-05 00:00:00

abstract：:The aim of this study was to present a model that uses multi-parametric quantitative MRI to estimate the presence of myelin and edema in the brain. The model relates simultaneous measurement of R1 and R2 relaxation rates and proton density to four partial volume compartments, consisting of myelin partial volume, cellu...

journal_title：Frontiers in neurology

authors： Warntjes M,Engström M,Tisell A,Lundberg P

更新日期：2016-02-17 00:00:00

abstract：:Robust and reliable stroke lesion segmentation is a crucial step toward employing lesion volume as an independent endpoint for randomized trials. The aim of this work was to develop and evaluate a novel method to segment sub-acute ischemic stroke lesions from fluid-attenuated inversion recovery (FLAIR) magnetic resona...

journal_title：Frontiers in neurology

authors： Subbanna NK,Rajashekar D,Cheng B,Thomalla G,Fiehler J,Arbel T,Forkert ND

更新日期：2019-05-24 00:00:00

abstract：:Accurate localization of the Seizure Onset Zone (SOZ) is crucial in patients with drug-resistance focal epilepsy. EEG with fMRI recording (EEG-fMRI) has been proposed as a complementary non-invasive tool, which can give useful additional information in the pre-surgical work-up. However, fMRI maps related to interictal...

journal_title：Frontiers in neurology

authors： Vaudano AE,Avanzini P,Tassi L,Ruggieri A,Cantalupo G,Benuzzi F,Nichelli P,Lemieux L,Meletti S

更新日期：2013-11-14 00:00:00

abstract：:Background: Regional cerebral oxygen saturation (rScO2) measured by near-infrared spectroscopy (NIRS) can be used to monitor brain oxygenation in extracorporeal membrane oxygenation (ECMO). ECMO patients that develop acute brain injuries (ABIs) are observed to have worse outcomes. We evaluated the association between ...

journal_title：Frontiers in neurology

authors： Khan I,Rehan M,Parikh G,Zammit C,Badjatia N,Herr D,Kon Z,Hogue C,Mazzeffi M

更新日期：2018-11-23 00:00:00

abstract：:Objectives: To identify and compare the cerebrospinal fluid (CSF) parameters that predict the presence of neonatal bacterial meningitis using optimal cutoff values, and to derive and compare predictive profiles based on a combination of individual parameters for the same purpose. Study Design: The retrospective compon...

journal_title：Frontiers in neurology

authors： Huang H,Tan J,Gong X,Li J,Wang L,Xu M,Zhang X,Zhang Y,Huang L

更新日期：2019-01-23 00:00:00

abstract：:Parkinson's disease (PD) is not a single entity but rather a heterogeneous neurodegenerative disorder. The present study aims to conduct a critical systematic review of the literature to describe the main pharmacological strategies to treat cognitive dysfunction and major depressive disorder in PD patients. We perform...

journal_title：Frontiers in neurology

authors： Sandoval-Rincón M,Sáenz-Farret M,Miguel-Puga A,Micheli F,Arias-Carrión O

更新日期：2015-03-31 00:00:00

abstract：:Disorders of the central nervous system sometimes cause severe sensory motor paralysis accompanied by gait impairment. Recently, there are several reports on the effectiveness of robot-assisted gait training for patients experiencing these issues. The purpose of this case report was to assess the neuromechanical effec...

journal_title：Frontiers in neurology

authors： Kadone H,Kubota S,Abe T,Noguchi H,Miura K,Koda M,Shimizu Y,Hada Y,Sankai Y,Suzuki K,Yamazaki M

更新日期：2020-03-31 00:00:00

abstract：:Purpose: Cell-based therapy offers new opportunities for the development of novel treatments to promote tissue repair, functional restoration, and cerebral metabolic balance. N-acetylasperate (NAA), Choline (Cho), and Creatine (Cr) are three major metabolites seen on proton magnetic resonance spectroscopy (MRS) that p...

journal_title：Frontiers in neurology

authors： Haque ME,Gabr RE,George SD,Boren SB,Vahidy FS,Zhang X,Arevalo OD,Alderman S,Narayana PA,Hasan KM,Friedman ER,Sitton CW,Savitz SI

更新日期：2019-02-25 00:00:00

abstract：:Given the increasing use of regenerative free muscle flaps for various reconstructive procedures and neuroprosthetic applications, there is great interest and value in their enhanced regeneration, revascularization, and reinnervation for improved functional recovery. Here, we implant polyimide-based mircroelectrodes o...

journal_title：Frontiers in neurology

authors： Srinivasan S,Vyas K,McAvoy M,Calvaresi P,Khan OF,Langer R,Anderson DG,Herr H

更新日期：2019-03-22 00:00:00

abstract：:In the present study, we investigated the genetic variation in a family with acute encephalopathy and retinitis pigmentosa. Nine of 25 people in this family underwent genetic testing. Three family members, namely, the proband and the proband's two sisters, showed symptoms resembling those of meningoencephalitis and si...

journal_title：Frontiers in neurology

authors： You C,Zeng W,Deng L,Lei Z,Gao X,Zhang VW,Wang Y

更新日期：2020-05-05 00:00:00

abstract：:Background: Educational interventions are needed to overcome knowledge-to-action gaps in clinical care. We previously tested the feasibility and potential efficacy of an educational intervention that facilitates treatment decisions in multiple sclerosis care. A demonstration of the usability of such an intervention is...

journal_title：Frontiers in neurology

authors： Saposnik G,Tobler PN,Caceres F,Terzaghi MA,Ruff C,Maurino J,Fruns Quintana M,Oh J,Montalban X,Mamdani M

更新日期：2018-07-10 00:00:00

abstract：:Gross motor impairments are common after stroke, but efficient and motivating therapies for these impairments are scarce. We present an innovative musical sonification therapy, especially designed to retrain patients' gross motor functions. Sonification should motivate patients and provide additional sensory input inf...

journal_title：Frontiers in neurology

authors： Scholz DS,Rohde S,Nikmaram N,Brückner HP,Großbach M,Rollnik JD,Altenmüller EO

更新日期：2016-06-30 00:00:00

abstract：:Tau plays an important pathological role in a group of neurodegenerative diseases called tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic encephalopathy and corticobasal degeneration. In each disease, tau self-assembles abnormally to form filaments that deposit in the brain. Tau is a nativ...

journal_title：Frontiers in neurology

authors： Oakley SS,Maina MB,Marshall KE,Al-Hilaly YK,Harrington CR,Wischik CM,Serpell LC

更新日期：2020-11-12 00:00:00

abstract：:Ischemic stroke is one of the leading causes for death and disability worldwide. In patients with large space-occupying infarction, the subsequent edema complicated by transtentorial herniation poses a lethal threat. Especially in patients with malignant middle cerebral artery infarction, brain swelling secondary to t...

journal_title：Frontiers in neurology

authors： Pallesen LP,Barlinn K,Puetz V

更新日期：2019-01-09 00:00:00

abstract：:Objectives: This article aims to evaluate the safety and effectiveness of endoscope-assisted surgery for chronic subdural hematoma (cSDH) in comparison with the burr-hole craniostomy. Methods: An electronic literature research was performed in MEDLINE, the Cochrane library, and EMBASE from the inception to February 18...

journal_title：Frontiers in neurology

authors： Guo S,Gao W,Cheng W,Liang C,Wu A

更新日期：2020-11-05 00:00:00

abstract：Background:The electrophysiological evidence supporting the therapeutic efficacy of multiple transcranial direct current stimulation (tDCS) sessions on consciousness improvement in patients with prolonged disorders of consciousness (DOCs) has not been firmly established. Objectives:To assess the effects of repeated tD...

journal_title：Frontiers in neurology

authors： Zhang Y,Song W,Du J,Huo S,Shan G,Li R

更新日期：2017-11-21 00:00:00

abstract：:Multiple sclerosis (MS) is a neurodegenerative disease characterized by lesions in the central nervous system (CNS). Inflammation and demyelination are the leading causes of neuronal death and brain lesions formation. The immune reactivity is believed to be essential in the neuronal damage in MS. Cytokines play import...

journal_title：Frontiers in neurology

authors： Goyal M,Khanna D,Rana PS,Khaibullin T,Martynova E,Rizvanov AA,Khaiboullina SF,Baranwal M

更新日期：2019-07-18 00:00:00

abstract：:Background: The relationship between varicella-zoster virus (VZV)-associated myelitis and aquaporin-4 immunoglobulin-G (AQP4-IgG) remains unknown. Case Report: We report a case of acute radiculomyelitis with longitudinal extensive hyperintensity signals traversing the brainstem until the upper thoracic cord in a 55-ye...

journal_title：Frontiers in neurology

authors： Eguchi H,Takeshige H,Nakajima S,Kanou M,Nakajima A,Fuse A,Fukae J,Miwa H,Shimo Y

更新日期：2020-11-23 00:00:00

abstract：:Pathological high-frequency oscillations are a novel marker used to improve the delineation of epileptogenic tissue and, hence, the outcome of epilepsy surgery. Their practical clinical utilization is curtailed by the inability to discriminate them from physiological oscillations due to frequency overlap. Although it ...

journal_title：Frontiers in neurology

authors： Kudlacek J,Chvojka J,Posusta A,Kovacova L,Hong SB,Weiss S,Volna K,Marusic P,Otahal J,Jiruska P

更新日期：2017-12-21 00:00:00

abstract：:Significant advances have been made in the understanding of the numerous mechanisms involved in Parkinson's disease (PD) pathogenesis. The identification of PD pathogenic mutations and the use of different animal models have contributed to better elucidate the processes underlying the disease. Here, we report a brief ...

journal_title：Frontiers in neurology

authors： Imbriani P,Schirinzi T,Meringolo M,Mercuri NB,Pisani A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Persistent postural-perceptual dizziness (PPPD) is a common functional vestibular disorder characterized by persistent symptoms of non-vertiginous dizziness and unsteadiness that are exacerbated by upright posture, self-motion, and exposure to complex or moving visual stimuli. Recent physiologic and neuroima...

journal_title：Frontiers in neurology

authors： Riccelli R,Passamonti L,Toschi N,Nigro S,Chiarella G,Petrolo C,Lacquaniti F,Staab JP,Indovina I

更新日期：2017-10-17 00:00:00

abstract：:Psychophysiological investigations of traumatic brain injury (TBI) are being conducted for several reasons, including the objective of learning more about the underlying physiological mechanisms of the pathological processes that can be initiated by a head injury. Additional goals include the development of objective ...

journal_title：Frontiers in neurology

authors： Rapp PE,Rosenberg BM,Keyser DO,Nathan D,Toruno KM,Cellucci CJ,Albano AM,Wylie SA,Gibson D,Gilpin AM,Bashore TR

更新日期：2013-07-22 00:00:00

abstract：:Background: Perinatal and perioperative brain injury is a fundamental problem in infants with severe congenital heart disease undergoing neonatal cardiac surgery with cardiopulmonary bypass. An impaired neuromotor and neurocognitive development is encountered and associated with a reduction in quality of life. New neu...

journal_title：Frontiers in neurology

authors： Stegeman R,Lamur KD,van den Hoogen A,Breur JMPJ,Groenendaal F,Jansen NJG,Benders MJNL

更新日期：2018-07-03 00:00:00

abstract：:Preterm-born infants frequently suffer from an array of neurological damage, collectively termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting with a neurodevelopmental disorder (e.g., autism spectrum disorder; attention deficit hyperactivity disorder) later in life. It is hypothe...

journal_title：Frontiers in neurology

authors： Fleiss B,Gressens P,Stolp HB

更新日期：2020-07-14 00:00:00