Stroke Lesion Segmentation in FLAIR MRI Datasets Using Customized Markov Random Fields.

abstract：:Perinatal hypoxic-ischemic encephalopathy (HIE) can lead to neurodevelopmental disorders, including cerebral palsy. Standard care for neonatal HIE includes therapeutic hypothermia, which provides partial neuroprotection; magnetic resonance imaging (MRI) is often used to assess injury and predict outcome after HIE. Imm...

journal_title：Frontiers in neurology

authors： Doman SE,Girish A,Nemeth CL,Drummond GT,Carr P,Garcia MS,Johnston MV,Kannan S,Fatemi A,Zhang J,Wilson MA

更新日期：2018-05-08 00:00:00

abstract：:Cranioplasty (CP) after decompressive craniectomy (DC) for trauma is a neurosurgical procedure that aims to restore esthesis, improve cerebrospinal fluid (CSF) dynamics, and provide cerebral protection. In turn, this can facilitate neurological rehabilitation and potentially enhance neurological recovery. However, CP ...

journal_title：Frontiers in neurology

authors： Iaccarino C,Kolias AG,Roumy LG,Fountas K,Adeleye AO

更新日期：2020-01-29 00:00:00

abstract：Background:Wernicke's encephalopathy (WE), a metabolic disorder due to thiamine deficiency, manifests with various neurological symptoms and signs. It has been known as a cause of vestibular dysfunction. Preliminary reports have proposed predominant involvement of the horizontal semicircular canals (HSCs). Objective:T...

journal_title：Frontiers in neurology

authors： Lee SH,Kim SH,Kim JM,Tarnutzer AA

更新日期：2018-03-12 00:00:00

abstract：:The relationship between circadian rhythm and epilepsy has been recognized for decades. Yet many questions underlying the complex mechanisms of their interaction remain elusive. A better understanding on this topic allows the development of accurate seizure-detection algorithm and alternative precise therapeutic strat...

journal_title：Frontiers in neurology

authors： Xu C,Yu J,Ruan Y,Wang Y,Chen Z

更新日期：2020-07-24 00:00:00

abstract：:Cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 are two crucial mediators contributing to blood-brain barrier (BBB) damage during cerebral ischemia. However, it is not known whether MMP-9 activation is involved in COX-2-mediated BBB disruption in ischemic stroke. In this study, we hypothesized that genetic...

journal_title：Frontiers in neurology

authors： Yang C,Yang Y,DeMars KM,Rosenberg GA,Candelario-Jalil E

更新日期：2020-08-20 00:00:00

abstract：:Background: Mild traumatic brain injuries (mTBIs) are a significant social, sport, and military health issue. In spite of advances in the clinical management of these injuries, the underlying pathophysiology is not well-understood. There is a critical need to advance objective biomarkers, allowing the identification a...

journal_title：Frontiers in neurology

authors： Raikes AC,Bajaj S,Dailey NS,Smith RS,Alkozei A,Satterfield BC,Killgore WDS

更新日期：2018-06-20 00:00:00

abstract：:Mutations in the Potassium channel subfamily T member 1 (KCNT1) gene have been reported in a range of epileptic encephalopathies. Here we report the case of a 12-year-old male suffering from multiple types of epileptic seizures and cognitive decline from the age of 10. The patient had four types of epileptic seizures,...

journal_title：Frontiers in neurology

authors： Jia Y,Lin Y,Li J,Li M,Zhang Y,Hou Y,Liu A,Zhang L,Li L,Xiang P,Ye J,Huang Z,Wang Y

更新日期：2019-02-05 00:00:00

abstract：:Background: Magnetic resonance imaging is a key diagnostic and monitoring tool in multiple Sclerosis (MS). While the substrates of motor and neuropsychological symptoms in MS have been extensively investigated, nystagmus-associated imaging signatures are relatively under studied. Accordingly, the objective of this stu...

journal_title：Frontiers in neurology

authors： Bede P,Finegan E,Chipika RH,Li Hi Shing S,Lambe J,Meaney J,Redmond J

更新日期：2018-08-23 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:Despite extensive research, the functions of the basal ganglia (BG) in movement control have not been fully understood. Eye movements, particularly saccades, are convenient indicators of BG function. Here, we review the main oculomotor findings reported in Parkinson's disease (PD) and genetic parkinsonian syndromes. P...

journal_title：Frontiers in neurology

authors： Pretegiani E,Optican LM

更新日期：2017-11-09 00:00:00

abstract：:Background: Transcranial direct current stimulation (tDCS) and therapy-based virtual reality (VR) have been investigated separately. They have shown promise as efficient and engaging new tools in the neurological rehabilitation of individuals with cerebral palsy (CP). However, the recent literature encourages investig...

journal_title：Frontiers in neurology

authors： da Silva TD,Fontes AMGG,de Oliveira-Furlan BS,Roque TT,Lima AII,de Souza BMM,Alberissi CAO,Silveira AC,de Moraes ÍAP,Collett J,Silva RP,Airoldi MJ,Ribeiro-Papa DC,Dawes H,Monteiro CBM

更新日期：2020-09-02 00:00:00

abstract：:The Boston Carpal Tunnel Questionnaire (BCTQ) is a scale that has been developed specifically for carpal tunnel syndrome (CTS). It consists of the Functional Status Scale (FSS) and the Symptom Severity Scale (SSS). It is the most widely used patient reported outcome measure in CTS and has been validated in many langua...

journal_title：Frontiers in neurology

authors： De Kleermaeker FGCM,Levels M,Verhagen WIM,Meulstee J

更新日期：2019-11-07 00:00:00

abstract：:There is currently no therapeutic drug treatment for traumatic brain injury (TBI) despite decades of experimental clinical trials. This may be because the mechanistic pathways for improving TBI outcomes have yet to be identified and exploited. As such, there remains a need to seek out new molecular targets and their d...

journal_title：Frontiers in neurology

authors： Hook G,Jacobsen JS,Grabstein K,Kindy M,Hook V

更新日期：2015-09-02 00:00:00

abstract：:Introduction: It remains unclear if tau imaging may assist diagnosis of chronic traumatic encephalopathy (CTE). Flortaucipir PET has shown superior frontal with medial temporal tau binding consistent with the provisional neuropathological criteria for mid-stage CTE in group-level analyses of retired symptomatic NFL pl...

journal_title：Frontiers in neurology

authors： Krishnadas N,Doré V,Lamb F,Groot C,McCrory P,Guzman R,Mulligan R,Huang K,O'Donnell M,Ponsford J,Hopwood M,Villemagne VL,Rowe CC

更新日期：2020-12-22 00:00:00

abstract：:Object: Diabetes is associated with cerebral vascular dysfunction and increased vascular cognitive impairment. The objective of this study was to use arterial spin labeling (ASL) perfusion-weighted magnetic resonance imaging to investigate whether cerebral perfusion was changed in newly-diagnosed children with type 1 ...

journal_title：Frontiers in neurology

authors： Song J,Cui S,Chen Y,Ye X,Huang X,Su H,Zhou Y,Liu X,Chen W,Shan X,Yan Z,Liu K

更新日期：2020-06-19 00:00:00

abstract：:Background: Cervical dystonia (CD) is a rare disorder, and health care providers might be unfamiliar with its presentation, thus leading to delay in the initial diagnosis. The lack of awareness displays the need to highlight the clinical features and treatment in cervical dystonia. In our cohort, we have identified an...

journal_title：Frontiers in neurology

authors： Supnet ML,Acuna P,Carr SJ,Kristoper de Guzman J,Al Qahtani X,Multhaupt-Buell T,Francoeur T,Aldykiewicz GE,Alluri PR,Campion L,Paul L,Ozelius L,Penney EB,Stephen CD,Dy-Hollins M,Sharma N

更新日期：2020-11-27 00:00:00

abstract：:Injuries to the immature optic radiation (OR) are associated with thinning of the retinal nerve fiber layer and corresponding visual field (VF) defects. The aim of the current study was to seek evidence for causal retrograde trans-synaptic degeneration by exploring the correspondence between the localization and exten...

journal_title：Frontiers in neurology

authors： Lennartsson F,Nilsson M,Flodmark O,Jacobson L,Larsson J

更新日期：2018-05-07 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercis...

journal_title：Frontiers in neurology

authors： Paré MF,Jasmin BJ

更新日期：2017-09-27 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2020.578924.]. ...

journal_title：Frontiers in neurology

authors： Binck S,Pauly C,Vaillant M,Hipp G,Gantenbein M,Krueger R,Diederich NJ

更新日期：2021-01-12 00:00:00

abstract：:Alzheimer's disease (AD) is the most prevalent form of late-onset dementia. AD affects the health of millions of people in the United States and worldwide. Currently, there are no approved therapies that can halt or reverse the clinical progression of AD. Traditionally, AD is characterized first by the appearance of a...

journal_title：Frontiers in neurology

authors： Hanslik KL,Ulland TK

更新日期：2020-09-18 00:00:00

abstract：:Background: Recent developments in mobile technology have enabled the investigation of human movements and mobility under natural conditions, i.e., in the home environment. Iron accumulation in the basal ganglia is deleterious in Parkinson's disease (i.e., iron accumulation with lower striatal level of dopamine). The ...

journal_title：Frontiers in neurology

authors： Hopfner F,Hobert MA,Maetzler C,Hansen C,Pham MH,Moreau C,Berg D,Devos D,Maetzler W,Fair-Park II study group.

更新日期：2019-08-08 00:00:00

abstract：Introduction:There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal designs. Aim:We investigated the differences in cognitive decline in AD compared to DLB over 4 ye...

journal_title：Frontiers in neurology

authors： Breitve MH,Chwiszczuk LJ,Brønnick K,Hynninen MJ,Auestad BH,Aarsland D,Rongve A

更新日期：2018-03-06 00:00:00

abstract：:Background and Purpose: Stability stratification of intracranial aneurysms (IAs) is crucial for individualized clinical management, especially for small IAs. We aim to develop and validate a nomogram based on clinical and morphological risk factors for individualized instability stratification of small IAs. Methods: S...

journal_title：Frontiers in neurology

authors： Zhu W,Li W,Tian Z,Zhang M,Zhang Y,Wang K,Zhang Y,Yang X,Liu J

更新日期：2021-01-15 00:00:00

abstract：:Paraneoplastic autoimmune neurological disorders reflect tumor-initiated immune responses against onconeural antigens. Symptoms and signs can affect the central and/or peripheral nervous systems, neuromuscular junction or muscle, and typically evolve subacutely before an underlying neoplasm is discovered. We describe ...

journal_title：Frontiers in neurology

authors： Zhu M,Ma Y,Zekeridou A,Lennon VA

更新日期：2020-12-10 00:00:00

abstract：:Background: Educational interventions are needed to overcome knowledge-to-action gaps in clinical care. We previously tested the feasibility and potential efficacy of an educational intervention that facilitates treatment decisions in multiple sclerosis care. A demonstration of the usability of such an intervention is...

journal_title：Frontiers in neurology

authors： Saposnik G,Tobler PN,Caceres F,Terzaghi MA,Ruff C,Maurino J,Fruns Quintana M,Oh J,Montalban X,Mamdani M

更新日期：2018-07-10 00:00:00

abstract：Background:Visual impairment affects up to 70% of stroke survivors. We designed an app (StrokeVision) to facilitate screening for common post stroke visual issues (acuity, visual fields, and visual inattention). We sought to describe the test time, feasibility, acceptability, and accuracy of our app-based digital visua...

journal_title：Frontiers in neurology

authors： Quinn TJ,Livingstone I,Weir A,Shaw R,Breckenridge A,McAlpine C,Tarbert CM

更新日期：2018-03-28 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:Aims: To investigate the relationship between clinical and imaging features of stroke patients with patent foramen ovale (PFO) and those with spontaneous intracranial artery dissection (SIAD). Materials and methods: We retrospectively examined both clinical and imaging results of 40 stroke patients with PFO and 29 wit...

journal_title：Frontiers in neurology

authors： Huang Y,Cheng Y,Shao B,Zhou X,Liang H,Zhuang J,Bi Y

更新日期：2019-04-24 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：:Introduction: Although patients with Parkinson's disease (PD) often suffer from oropharyngeal dysphagia, knowledge about the underlying pathophysiological mechanisms is limited. Substance P (SP) is a localization-independent neurotransmitter of the entire nervous system. Reduced levels of SP were found in saliva of pa...

journal_title：Frontiers in neurology

authors： Schröder JB,Marian T,Claus I,Muhle P,Pawlowski M,Wiendl H,Suntrup-Krueger S,Meuth SG,Dziewas R,Ruck T,Warnecke T

更新日期：2019-04-16 00:00:00