Cognitive Processing Impacts High Frequency Intracranial EEG Activity of Human Hippocampus in Patients With Pharmacoresistant Focal Epilepsy.

abstract：:Purpose: To assess the efficacy and safety of rituximab treatment as second-line immunotherapy in pediatric cases of anti-NMDA receptor (NMDAR) encephalitis. Methods: We retrospectively recruited 8 patients with anti-NMDAR encephalitis who were treated with rituximab as second-line immunotherapy. We evaluated the clin...

journal_title：Frontiers in neurology

authors： Dou X,Li D,Wu Y,Wang Z,Yang L,Ma N,Wang D,Li X

更新日期：2020-12-14 00:00:00

abstract：Objective:To investigate the correlation between initial response to antiepileptic drugs (AEDs) and long-term outcomes after 3 years in patients with newly diagnosed epilepsy. Methods:This prospective study included 204 patients with newly diagnosed epilepsy, who were followed-up for at least 36 months. The long-term ...

journal_title：Frontiers in neurology

authors： Xia L,Ou S,Pan S

更新日期：2017-12-08 00:00:00

abstract：:This study presents the first implementation of functional ultrasound (fUS) imaging of the spinal cord to monitor local hemodynamic response to epidural electrical spinal cord stimulation (SCS) on two small and large animal models. SCS has been successfully applied to control chronic refractory pain and recently was e...

journal_title：Frontiers in neurology

authors： Song P,Cuellar CA,Tang S,Islam R,Wen H,Huang C,Manduca A,Trzasko JD,Knudsen BE,Lee KH,Chen S,Lavrov IA

更新日期：2019-03-26 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercis...

journal_title：Frontiers in neurology

authors： Paré MF,Jasmin BJ

更新日期：2017-09-27 00:00:00

abstract：:Background and Purpose: Internal carotid artery stenosis (ICAS)≥70% is a leading cause of ischemic cerebrovascular events (ICVEs). However, a considerable percentage of stroke survivors with symptomatic ICAS (sICAS) have <70% stenosis with a vulnerable plaque. Whether the length of ICAS is associated with high risk of...

journal_title：Frontiers in neurology

authors： Elhfnawy AM,Heuschmann PU,Pham M,Volkmann J,Fluri F

更新日期：2019-04-09 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:Poststroke depression (PSD) is the most prevalent psychiatric disorder after stroke, which is independently correlated with negative clinical outcome. The identification of specific biomarkers could help to increase the sensitivity of PSD diagnosis and elucidate its pathophysiological mechanisms. The aim of current st...

journal_title：Frontiers in neurology

authors： Levada OA,Troyan AS

更新日期：2018-07-16 00:00:00

abstract：:This study aims to quantify passive muscle stiffness of spastic wrist flexors in stroke survivors using shear wave elastography (SWE) and to correlate with neural and non-neural contributors estimated from a biomechanical model to hyper-resistance measured during passive wrist extension. Fifteen hemiplegic individuals...

journal_title：Frontiers in neurology

authors： Leng Y,Wang Z,Bian R,Lo WLA,Xie X,Wang R,Huang D,Li L

更新日期：2019-07-10 00:00:00

abstract：:Dizziness and imbalance are clinically poorly defined terms, which affect ~30% of people over 65 years of age. In these people, it is often difficult to define the primary cause of dizziness, as it can stem from cardiovascular, vestibular, psychological, and neuromuscular causes. However, identification of the primary...

journal_title：Frontiers in neurology

authors： Chau AT,Menant JC,Hübner PP,Lord SR,Migliaccio AA

更新日期：2015-12-24 00:00:00

abstract：:Primary angiitis of the central nervous system (PACNS) is a rare autoimmune vasculitis limited to the CNS often causing substantial disability. Understanding of this disease is impaired by the lack of available biomaterial. Here, we collected cerebrospinal fluid (CSF) from patients with PACNS and matched controls and ...

journal_title：Frontiers in neurology

authors： Ruland T,Wolbert J,Gottschalk MG,König S,Schulte-Mecklenbeck A,Minnerup J,Meuth SG,Groß CC,Wiendl H,Meyer Zu Hörste G

更新日期：2018-06-05 00:00:00

abstract：:We describe three patients diagnosed with bilateral vestibular dysfunction associated with the jet propellant type-eight (JP-8) fuel exposure. Chronic exposure to aromatic and aliphatic hydrocarbons, which are the main constituents of JP-8 military aircraft jet fuel, occurred over 3-5 years' duration while working on ...

journal_title：Frontiers in neurology

authors： Fife TD,Robb MJA,Steenerson KK,Saha KC

更新日期：2018-05-16 00:00:00

abstract：:Background: Late latency auditory evoked potentials (LLAEPs) provide objective evidence of an individual's central auditory processing abilities. Electrically evoked cortical auditory evoked potentials (eCAEPs) are a type of LLAEP that provides an objective measure of aided speech perception and auditory processing ab...

journal_title：Frontiers in neurology

authors： Pike M,Biagio-de Jager L,le Roux T,Hofmeyr LM

更新日期：2020-04-28 00:00:00

abstract：:The vestibular system plays a crucial role in the multisensory control of balance. When vestibular function is lost, essential tasks such as postural control, gaze stabilization, and spatial orientation are limited and the quality of life of patients is significantly impaired. Currently, there is no effective treatmen...

journal_title：Frontiers in neurology

authors： Perez Fornos A,Guinand N,van de Berg R,Stokroos R,Micera S,Kingma H,Pelizzone M,Guyot JP

更新日期：2014-04-29 00:00:00

abstract：:Background and Objective: One-third of ischemic strokes have no identifiable cause following standard evaluation. In 2014, researchers have proposed the concept of Embolic Stroke of Undetermined Source (ESUS). The purpose of this study was to report the clinical characteristics of ESUS and its difference from cardioge...

journal_title：Frontiers in neurology

authors： Wang W,Tang X,Liu W,Jia K,Zhao X,Yu F

更新日期：2020-02-05 00:00:00

abstract：:A synthetic peptide with antisecretory activity, antisecretory factor (AF)-16, improves injury-related deficits in water and ion transport and decreases intracranial pressure after experimental cold lesion injury and encephalitis although its role in traumatic brain injury (TBI) is unknown. AF-16 or an inactive refere...

journal_title：Frontiers in neurology

authors： Clausen F,Hansson HA,Raud J,Marklund N

更新日期：2017-02-14 00:00:00

abstract：:Mutations in both copies (homozygous or compound heterozygous) of the gene encoding the lysosomal enzyme glucocerebrosidase, which cleaves the glycolipid glucocerebroside into glucose and ceramide cause Gaucher disease. However, multiple independent studies have also reported an association between GBA mutations and P...

journal_title：Frontiers in neurology

authors： Almeida Mdo R

更新日期：2012-04-27 00:00:00

abstract：:Functional magnetic resonance imaging studies suggest that different subcortico-cortical circuits control different aspects of Parkinsonian rest tremor. The basal ganglia were proposed to drive tremor onset, and the cerebellum was suggested to be responsible for tremor maintenance ("dimmer-switch" hypothesis). Althoug...

journal_title：Frontiers in neurology

authors： Hirschmann J,Abbasi O,Storzer L,Butz M,Hartmann CJ,Wojtecki L,Schnitzler A

更新日期：2019-03-07 00:00:00

abstract：:Patient registries offer a powerful and practical means of real-world data collection system for rare diseases. Many guidelines have been released to standardize patient registries, although most of them do not address issues specific to rare disease patient registries. In November 2018, the European Medicines Agency ...

journal_title：Frontiers in neurology

authors： Marques R,Thole H,Ruiz de Morales JG

更新日期：2020-05-15 00:00:00

abstract：:Epilepsy is a neurological disorder in which, in many cases, there is poor pharmacological control of seizures. Nevertheless, it may respond beneficially to alternative treatments such as dietary therapy, like the ketogenic diet or caloric restriction. One of the mechanisms of these diets is to produce a hyperpolariza...

journal_title：Frontiers in neurology

authors： Rubio C,Luna R,Rosiles A,Rubio-Osornio M

更新日期：2020-11-05 00:00:00

abstract：:Background: Perinatal and perioperative brain injury is a fundamental problem in infants with severe congenital heart disease undergoing neonatal cardiac surgery with cardiopulmonary bypass. An impaired neuromotor and neurocognitive development is encountered and associated with a reduction in quality of life. New neu...

journal_title：Frontiers in neurology

authors： Stegeman R,Lamur KD,van den Hoogen A,Breur JMPJ,Groenendaal F,Jansen NJG,Benders MJNL

更新日期：2018-07-03 00:00:00

abstract：INTRODUCTION:In tinnitus treatment, there is a tendency to shift from a "one size fits all" to a more individual, patient-tailored approach. Insight in the heterogeneity of the tinnitus spectrum might improve the management of tinnitus patients in terms of choice of treatment and identification of patients with severe ...

journal_title：Frontiers in neurology

authors： van den Berge MJC,Free RH,Arnold R,de Kleine E,Hofman R,van Dijk JMC,van Dijk P

更新日期：2017-04-03 00:00:00

abstract：:Thyroid hormones are of fundamental importance for brain development and essential factors to warrant brain functions throughout life. Their actions are mediated by binding to specific intracellular and membranous receptors regulating genomic and non-genomic mechanisms in neurons and populations of glial cells, respec...

journal_title：Frontiers in neurology

authors： Talhada D,Santos CRA,Gonçalves I,Ruscher K

更新日期：2019-10-18 00:00:00

abstract：:Single time point positron emission tomography (PET) studies of patients with amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD), have demonstrated hypometabolism or hypermetabolism in certain brain regions. To determine whether longitudinal (at baseline and 20.4 months later) PET and magnetic resonan...

journal_title：Frontiers in neurology

authors： Rajagopalan V,Pioro EP

更新日期：2019-03-19 00:00:00

abstract：:Formulaic expressions naturally convey affective content. The unique formal and functional characteristics of idioms, slang, expletives, proverbs, conversational speech formulas, and the many other conventional expressions in this repertory have been well-described: these include unitary form, conventionalized and non...

journal_title：Frontiers in neurology

authors： Sidtis DVL,Sidtis JJ

更新日期：2018-07-24 00:00:00

abstract：:Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more frequently observed in infants of smoking mothers. The global prevalence of smoking during pregnancy is 1.7% and up to 8.1% of women in Europe smoke du...

journal_title：Frontiers in neurology

authors： Bednarczuk N,Milner A,Greenough A

更新日期：2020-10-23 00:00:00

abstract：:Introduction: Few studies have examined the motor, cognitive, and emotional factors involved in effective money management in persons with multiple sclerosis (MS). The aim of this study was to assess money management in persons MS and examine whether cognitive, motor, and emotional processes can predict money manageme...

journal_title：Frontiers in neurology

authors： Yael G,Nancy C,John D

更新日期：2019-10-23 00:00:00

abstract：:Rhythmic auditory cueing is a well-accepted tool for gait rehabilitation in Parkinson's disease (PD), which can now be applied in a performance-adapted fashion due to technological advance. This study investigated the immediate differences on gait during a prolonged, 30 min, walk with performance-adapted (intelligent)...

journal_title：Frontiers in neurology

authors： Ginis P,Heremans E,Ferrari A,Dockx K,Canning CG,Nieuwboer A

更新日期：2017-04-06 00:00:00

abstract：:α-synuclein is involved in the pathogenesis of multiple system atrophy (MSA) and can be regulated by peripheral immune activation (PIA). We aimed to clarify the correlations between PIA and the prevalence of MSA and to analyze the role of PIA in the progression of the disease. A total of 321 patients with probable MSA...

journal_title：Frontiers in neurology

authors： Cao B,Chen X,Zhang L,Wei Q,Liu H,Feng W,Chen Y,Shang H

更新日期：2020-07-07 00:00:00

abstract：:Melodic intonation therapy (MIT) is a treatment program for the rehabilitation of aphasic patients with speech production disorders. We report a case of severe chronic non-fluent aphasia unresponsive to several years of conventional therapy that showed a marked improvement following intensive 9-day training on the Jap...

journal_title：Frontiers in neurology

authors： Tabei KI,Satoh M,Nakano C,Ito A,Shimoji Y,Kida H,Sakuma H,Tomimoto H

更新日期：2016-09-19 00:00:00

abstract：:Traumatic brain injury (TBI) is a major health concern worldwide. Laboratory studies utilizing animal models of TBI are essential for addressing pathological mechanisms of brain injury and development of innovative treatments. Over the past 75 years, pioneering head injury researchers have devised and tested a number ...

journal_title：Frontiers in neurology

authors： Lyeth BG

更新日期：2016-12-02 00:00:00