Improved Neural Processing Efficiency in a Chronic Aphasia Patient Following Melodic Intonation Therapy: A Neuropsychological and Functional MRI Study.

abstract：:Introduction: Traumatic brain injury (TBI) is a global epidemic. The incidence of TBI in low and middle-income countries (LMICs) is three times greater than in high-income countries (HICs). Decompressive craniectomy (DC) is a surgical procedure to reduce intracranial pressure (ICP) and prevent secondary injury. Multip...

journal_title：Frontiers in neurology

authors： Rubiano AM,Carney N,Khan AA,Ammirati M

更新日期：2019-10-10 00:00:00

abstract：:Increasing evidence suggests an association between gastrointestinal (GI) disorders and susceptibility and progress of Parkinson's disease (PD). Gut-brain axis has been proposed to play important roles in the pathogenesis of PD, though the exact pathophysiologic mechanism has yet to be elucidated. Here, we discuss the...

journal_title：Frontiers in neurology

authors： Chao YX,Gulam MY,Chia NSJ,Feng L,Rotzschke O,Tan EK

更新日期：2020-08-25 00:00:00

abstract：:The relationship between circadian rhythm and epilepsy has been recognized for decades. Yet many questions underlying the complex mechanisms of their interaction remain elusive. A better understanding on this topic allows the development of accurate seizure-detection algorithm and alternative precise therapeutic strat...

journal_title：Frontiers in neurology

authors： Xu C,Yu J,Ruan Y,Wang Y,Chen Z

更新日期：2020-07-24 00:00:00

abstract：:Cognitive impairment is prevalent and disabling in multiple sclerosis (MS) and is severely impacting quality of life (QoL). Aside its routine assessment in clinical care, it should more often be implemented as endpoint/outcome measure in clinical trials. However, a fundamental aspect-often neglected in clinical practi...

journal_title：Frontiers in neurology

authors： Beste C,Ziemssen T

更新日期：2020-08-28 00:00:00

abstract：:Cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 are two crucial mediators contributing to blood-brain barrier (BBB) damage during cerebral ischemia. However, it is not known whether MMP-9 activation is involved in COX-2-mediated BBB disruption in ischemic stroke. In this study, we hypothesized that genetic...

journal_title：Frontiers in neurology

authors： Yang C,Yang Y,DeMars KM,Rosenberg GA,Candelario-Jalil E

更新日期：2020-08-20 00:00:00

abstract：OBJECTIVE:Evaluate medical students' communication and professionalism skills from the perspective of the ambulatory patient and later compare these skills in their first year of residency. METHODS:Students in third year neurology clerkship clinics see patients alone followed by a revisit with an attending neurologist...

journal_title：Frontiers in neurology

authors： Davis LE,King MK,Wayne SJ,Kalishman SG

更新日期：2012-06-20 00:00:00

abstract：:Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more frequently observed in infants of smoking mothers. The global prevalence of smoking during pregnancy is 1.7% and up to 8.1% of women in Europe smoke du...

journal_title：Frontiers in neurology

authors： Bednarczuk N,Milner A,Greenough A

更新日期：2020-10-23 00:00:00

abstract：:Background and Objective: One-third of ischemic strokes have no identifiable cause following standard evaluation. In 2014, researchers have proposed the concept of Embolic Stroke of Undetermined Source (ESUS). The purpose of this study was to report the clinical characteristics of ESUS and its difference from cardioge...

journal_title：Frontiers in neurology

authors： Wang W,Tang X,Liu W,Jia K,Zhao X,Yu F

更新日期：2020-02-05 00:00:00

abstract：:Vestibular impairment has become a frequent consequence following blast-related traumatic brain injury (bTBI) in military personnel and Veterans. Behavioral outcomes such as depression, fear and anxiety are also common comorbidities of bTBI. To accelerate pre-clinical research and therapy developments, there is a need...

journal_title：Frontiers in neurology

authors： Dickerson MR,Bailey ZS,Murphy SF,Urban MJ,VandeVord PJ

更新日期：2020-07-15 00:00:00

abstract：:To investigate the usefulness of pain-related evoked potentials (PREP) elicited by electrical stimulation for the identification of small fiber involvement in patients with mixed fiber neuropathy (MFN). Eleven MFN patients with clinical signs of large fiber impairment and neuropathic pain and ten healthy controls unde...

journal_title：Frontiers in neurology

authors： Hansen N,Kahn AK,Zeller D,Katsarava Z,Sommer C,Üçeyler N

更新日期：2015-12-07 00:00:00

abstract：:Aim: The aim of the study was to investigate the effect of the onset of Parkinson's disease (PD) on life satisfaction. Method: Data from 2008, 2011, and 2014 were used from a population-based prospective cohort (German Ageing Survey; 8,982 observations in FE regression analysis) of community-residing individuals in th...

journal_title：Frontiers in neurology

authors： Buczak-Stec EW,König HH,Hajek A

更新日期：2018-07-25 00:00:00

abstract：:Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysphagia during early postnatal life in the LgDel mouse model of 22q11DS ...

journal_title：Frontiers in neurology

authors： Welby L,Caudill H,Yitsege G,Hamad A,Bunyak F,Zohn IE,Maynard T,LaMantia AS,Mendelowitz D,Lever TE

更新日期：2020-01-31 00:00:00

abstract：:Objective: The objective of this study was to investigate the roles and mechanisms of inflammatory mediators NLRP3 and IL-1β in refractory temporal epilepsy brain injury. Method: First, the brain tissue and the peripheral blood of children undergoing intractable temporal lobe epilepsy surgery were analyzed as research...

journal_title：Frontiers in neurology

authors： Wu C,Zhang G,Chen L,Kim S,Yu J,Hu G,Chen J,Huang Y,Zheng G,Huang S

更新日期：2020-02-07 00:00:00

abstract：:The mechanisms involved in traumatic brain injury have yet to be fully characterized. One mechanism that, especially in high-energy trauma, could be of importance is cavitation. Cavitation can be described as a process of vaporization, bubble generation, and bubble implosion as a result of a decrease and subsequent in...

journal_title：Frontiers in neurology

authors： Cao Y,Risling M,Malm E,Sondén A,Bolling MF,Sköld MK

更新日期：2016-02-01 00:00:00

abstract：:Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this fact is well known, there has been a remarkable lack of progress in determining the pathophysiological mechanisms behind fatigue and the establishment of effective treatments. The main barrier has been the lack of a unified...

journal_title：Frontiers in neurology

authors： Rudroff T,Kindred JH,Ketelhut NB

更新日期：2016-08-02 00:00:00

abstract：:We describe and evaluate a pre-processing method based on a periodic spiral sampling of diffusion-gradient directions for high angular resolution diffusion magnetic resonance imaging. Our pre-processing method incorporates prior knowledge about the acquired diffusion-weighted signal, facilitating noise reduction. Peri...

journal_title：Frontiers in neurology

authors： Sepehrband F,Choupan J,Caruyer E,Kurniawan ND,Gal Y,Tieng QM,McMahon KL,Vegh V,Reutens DC,Yang Z

更新日期：2015-01-12 00:00:00

abstract：:Background: In functional movement disorders, explicit movements are impaired, while implicit movements are preserved. Furthermore, there is evidence that the sense of agency is abnormal. Aim: We aimed to investigate how motor responses and sense of agency were affected by subliminal or supraliminal cues in people wit...

journal_title：Frontiers in neurology

authors： Huys AML,Edwards MJ,Bhatia KP,Haggard P

更新日期：2020-09-11 00:00:00

abstract：:Background: Writer's cramp (WC) is a task-specific focal hand dystonia presenting with pain, stiffness and/or tremor while writing. We explored the involvement of cortical and brainstem circuits by measuring intermuscular coherence (IMC) and pre-pulse inhibition (PPI) of the blink reflex. Methods: IMC was measured in ...

journal_title：Frontiers in neurology

authors： Choudhury S,Singh R,Chatterjee P,Trivedi S,Shubham S,Baker MR,Kumar H,Baker SN

更新日期：2018-07-02 00:00:00

abstract：:Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent retriever (SR) thr...

journal_title：Frontiers in neurology

authors： Chuming H,Yifan H,Ke X,Chukai X,Weijie Z,Hui L,Guoyi P,Xiaoyong Z,Peifeng Z,Chuwei C

更新日期：2020-10-22 00:00:00

abstract：:Introduction: Eslicarbazepine acetate (ESL) is an antiepileptic drug approved as monotherapy or add-on for the treatment of epilepsy with seizures of focal onset. ESL owns a good profile in terms of efficacy and tolerability, but its effects on EEG activity and connectivity are unknown. The purpose of this study was t...

journal_title：Frontiers in neurology

authors： Pellegrino G,Mecarelli O,Pulitano P,Tombini M,Ricci L,Lanzone J,Brienza M,Davassi C,Di Lazzaro V,Assenza G

更新日期：2018-12-11 00:00:00

abstract：:Sleep complaints increase profoundly with age; prevalence estimates of insomnia in the elderly reach up to 37%. The three major types of nocturnal complaints are difficulties initiating (DIS) and maintaining (DMS) sleep and early morning awakening (EMA), of which the latter appears most characteristic for aging. The n...

journal_title：Frontiers in neurology

authors： Stoffers D,Moens S,Benjamins J,van Tol MJ,Penninx BW,Veltman DJ,Van der Wee NJ,Van Someren EJ

更新日期：2012-06-28 00:00:00

abstract：:Ischemic stroke is a multi-factorial cerebrovascular disease with high worldwide morbidity and mortality. In the past few years, multiple studies have revealed the underlying mechanism of ischemia/reperfusion injury, including calcium overload, amino acid toxicity, oxidative stress, and inflammation. Connexin 43 (Cx43...

journal_title：Frontiers in neurology

authors： Liang Z,Wang X,Hao Y,Qiu L,Lou Y,Zhang Y,Ma D,Feng J

更新日期：2020-07-31 00:00:00

abstract：:Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term ...

journal_title：Frontiers in neurology

authors： Zhang R,Liu G,Jiang Y,Li G,Pan Y,Wang Y,Wei Z,Wang J,Wang Y

更新日期：2018-10-02 00:00:00

abstract：:We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as dependent on voltage-gated, high-threshold P/Q-type channels. Here, we te...

journal_title：Frontiers in neurology

authors： Kezunovic N,Hyde J,Goitia B,Bisagno V,Urbano FJ,Garcia-Rill E

更新日期：2013-11-06 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：:Background: Ischemic cerebral infarction is a severe clinical condition that can cause serious mortality. Artesunate, an anti-malarial drug that is widely used in cancer treatment, is known to facilitate accelerated cell apoptosis. The aim of this study is to explore the possible neuroprotective effects of artesunate ...

journal_title：Frontiers in neurology

authors： Shao M,Shen Y,Sun H,Meng D,Huo W,Qi X

更新日期：2018-08-17 00:00:00

abstract：:The purpose of this study was to evaluate whether it is possible to restore the high-frequency angular vestibulo-ocular reflex (aVOR) in patients suffering from a severe bilateral vestibulopathy (BV) and implanted with a vestibular implant prototype. Three patients (S1-3) participated in the study. They received a pro...

journal_title：Frontiers in neurology

authors： Guinand N,Van de Berg R,Cavuscens S,Ranieri M,Schneider E,Lucieer F,Kingma H,Guyot JP,Pérez Fornos A

更新日期：2017-11-14 00:00:00

abstract：:Objectives: Patient-reported outcomes gain importance for the assessment of auditory abilities in cochlear implant users and for the evaluation of auditory rehabilitation. Aims of the study were to explore the interrelation of self-reported improvements in auditory ability with improvements in speech comprehension and...

journal_title：Frontiers in neurology

authors： Wallhäusser-Franke E,Balkenhol T,Hetjens S,Rotter N,Servais JJ

更新日期：2018-09-10 00:00:00

abstract：:The therapy of focal epilepsy remains unsatisfactory for as many as 25% of patients. The photolysis of caged-γ-aminobutyric acid (caged-GABA) represents a novel and alternative option for the treatment of intractable epilepsy. Our previous experimental results have demonstrated that the use of blue light produced by l...

journal_title：Frontiers in neurology

authors： Wang D,Yu Z,Yan J,Xue F,Ren G,Jiang C,Wang W,Piao Y,Yang X

更新日期：2017-05-18 00:00:00

abstract：:Sensorineural hearing loss is the most common long-term deficit after pneumococcal meningitis (PM), occurring in up to 30% of surviving patients. The infection and the following overshooting inflammatory host response damage the vulnerable sensory cells of the inner ear, resulting in loss of hair cells and spiral gang...

journal_title：Frontiers in neurology

authors： Erni ST,Fernandes G,Buri M,Perny M,Rutten RJ,van Noort JM,Senn P,Grandgirard D,Roccio M,Leib SL

更新日期：2019-06-10 00:00:00