Abstract：
:Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term effects of particulate matter <2.5 μm in diameter (PM2.5) and particulate matter <10 μm in diameter (PM10) on ischemic stroke mortality and hemorrhagic stroke mortality in Beijing, China. Methods: We used an ecological study design and quasi-Poisson generalized additive models to evaluate the association of PM2.5 and PM10 and cerebrovascular diseases mortality, as well as ischemic- and hemorrhagic stroke mortality. In the model, we controlled long-term and season trends, temperature, and relative humidity, the day of the week and air pollution. For cerebrovascular diseases mortality, we examined the effects stratified by sex and age with different lag days. Results: A total of 48,122 deaths for cerebrovascular disease (32,799 deaths for ischemic stroke and 13,051 deaths for hemorrhagic stroke) were included in the study. PM2.5 was associated with stroke mortality. The 10 μg/m3 increase of PM2.5 was associated with the increase of mortality, 0.27% (95% CI, 0.12-0.43%) for cerebrovascular diseases, 0.23% (95% CI, 0.04-0.42%) for ischemic stroke and 0.37% (95% CI, 0.07-0.67%) for hemorrhagic stroke -. The associations between PM10 and mortality were also detected for cerebrovascular diseases and ischemic stroke, but not in hemorrhagic stroke. The stratified analysis suggested age and gender did not modify the effects of PM on mortality significantly. Conclusions: Our study suggested that short-term exposure to ambient PM was associated with the risk of stroke mortality.
journal_name
Front Neuroljournal_title
Frontiers in neurologyauthors
Zhang R,Liu G,Jiang Y,Li G,Pan Y,Wang Y,Wei Z,Wang J,Wang Ydoi
10.3389/fneur.2018.00827subject
Has Abstractpub_date
2018-10-02 00:00:00pages
827issn
1664-2295journal_volume
9pub_type
杂志文章abstract：:Background: Ischemic cerebral infarction is a severe clinical condition that can cause serious mortality. Artesunate, an anti-malarial drug that is widely used in cancer treatment, is known to facilitate accelerated cell apoptosis. The aim of this study is to explore the possible neuroprotective effects of artesunate ...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00634
更新日期：2018-08-17 00:00:00
abstract：:Objective: Lipohyalinosis or atherosclerosis might be responsible for single subcortical infarctions (SSIs); however, ways of differentiating between the two clinically remain uncertain. We aimed to investigate whether consecutive slides on axial view or transversal diameter is more effective to differentiate mechanis...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00336
更新日期：2019-04-09 00:00:00
abstract：:Increasing evidence suggests an association between gastrointestinal (GI) disorders and susceptibility and progress of Parkinson's disease (PD). Gut-brain axis has been proposed to play important roles in the pathogenesis of PD, though the exact pathophysiologic mechanism has yet to be elucidated. Here, we discuss the...
journal_title：Frontiers in neurology
pub_type： 杂志文章,评审
doi：10.3389/fneur.2020.00849
更新日期：2020-08-25 00:00:00
abstract：:Objective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization. Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal aneurysms treated ...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00429
更新日期：2019-04-25 00:00:00
abstract：:Epilepsy may reflect a focal abnormality of cerebral tissue, but the generation of seizures typically involves propagation of abnormal activity through cerebral networks. We examined epileptiform discharges (spikes) with dense array electroencephalography (dEEG) in five patients to search for the possible engagement o...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2013.00055
更新日期：2013-05-15 00:00:00
abstract：:Background: Agoraphobia was described in 1871 as a condition of fear-related alterations in spatial orientation and locomotor control triggered by places or situations that might cause a patient to panic and feel trapped. In contemporary nosology, however, this original concept of agoraphobia was split into two diagno...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00874
更新日期：2019-08-13 00:00:00
abstract：:Background: The leading cause of death in China is stroke, a condition that also contributes heavily to the disease burden. Nontraumatic intracerebral hemorrhage (ICH) is the second most common cause of stroke. Compared to Western countries, in China the proportion of ICH is significantly higher. Standardized treatmen...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.01091
更新日期：2018-12-11 00:00:00
abstract：:Introduction: Safe driving requires integration of higher-order cognitive and motor functions, which are commonly compromised in patients with antibody-mediated encephalitis (AME) associated with N-methyl-D-aspartate receptors or leucine-rich glioma-inactivated 1 autoantibodies. How these deficits influence the return...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2020.00678
更新日期：2020-07-28 00:00:00
abstract：:Mitochondrial complex III deficiency nuclear type 2 is an autosomal-recessive disorder caused by mutations in TTC19 gene. TTC19 is involved in the preservation of mitochondrial complex III, which is responsible for transfer of electrons from reduced coenzyme Q to cytochrome C and thus, contributes to the formation of ...
journal_title：Frontiers in neurology
pub_type：
doi：10.3389/fneur.2019.00944
更新日期：2019-09-04 00:00:00
abstract：:Background: Increasing evidence implicates involvement of the innate immune system in the initiation and progression of Parkinson's disease (PD). Monocytes and monocyte-derived cells perform a number of functions, such as phagocytosis, chemotaxis, and cytokine secretion, which may be particularly relevant to PD pathol...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00870
更新日期：2018-10-16 00:00:00
abstract：:Background: Headache associated with Moyamoya disease (HAMD) in the Chinese population is not well-described. The long-term outcome of surgical revascularization and natural course of HAMD has not been disclosed either. Methods: A headache screening questionnaire in China based on the ICHD2 and a face-to-face intervie...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2020.605636
更新日期：2020-11-26 00:00:00
abstract：:Background: Elderly patients account for 30% of acute ischemic stroke (AIS) but are under-represented in randomized controlled trials of endovascular thrombectomy (EVT). Meta-analysis of "real world" studies evaluating 90-day outcomes in elderly patients ≥80 years have been limited to small numbers undergoing EVT with...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00254
更新日期：2019-03-20 00:00:00
abstract：:The dopamine (DA) precursor l-DOPA has been the most effective treatment for Parkinson's disease (PD) for over 40 years. However, the response to this treatment changes with disease progression, and most patients develop dyskinesias (abnormal involuntary movements) and motor fluctuations within a few years of l-DOPA t...
journal_title：Frontiers in neurology
pub_type： 杂志文章,评审
doi：10.3389/fneur.2014.00242
更新日期：2014-12-15 00:00:00
abstract：OBJECTIVE:Tinnitus is a common symptom of hearing impairment. Patients who are bilaterally hard of hearing are often affected by tinnitus. However, they cannot undergo any of the standard tinnitus therapies, since they rely on hearing. Cochlear implantation (CI) used to treat severe hearing disabilities, such as bilate...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2017.00158
更新日期：2017-04-25 00:00:00
abstract：:With the advent of susceptibility-weighted imaging (SWI), the ability to identify cerebral microbleeds (CMBs) associated with mild traumatic brain injury (mTBI) has become increasingly commonplace. Nevertheless, the clinical significance of post-traumatic CMBs remains controversial partly because it is unclear whether...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00948
更新日期：2018-11-13 00:00:00
abstract：:Traumatic brain injury (TBI) is a major cause of death worldwide. Depending on the severity of the injury, TBI can reflect a broad range of consequences such as speech impairment, memory disturbances, and premature death. In this study, embryonic neural stem cells (ENSC) were isolated from E14 mouse embryos and cultur...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00895
更新日期：2018-10-24 00:00:00
abstract：:X-linked adrenoleukodystrophy (X-ALD) is a rare neurological disorder with a highly complex clinical presentation. Adrenal function, spinal cord, peripheral nerves, and cerebral white matter are commonly affected in adult-onset male patients. Here, we report a family with unusual presentation of X-ALD. The 19-year-old...
journal_title：Frontiers in neurology
pub_type：
doi：10.3389/fneur.2018.00271
更新日期：2018-04-23 00:00:00
abstract：:Seizures are an infrequent and serious neurological complication of SARS-CoV-2 infection, with limited data describing the etiology and the clinical context in which these occur or the associated electrographic and imaging findings. This series details four cases of seizures occurring in patients with COVID-19 with di...
journal_title：Frontiers in neurology
pub_type：
doi：10.3389/fneur.2020.576329
更新日期：2020-11-05 00:00:00
abstract：:Background and Aim: Reliable, valid and sensitive measures of dual-task-associated impairments in patients with Parkinson's disease (PD) may reveal progressive deficits unnoticed under single-task walking. The aim of this study was to quantitatively identify markers of progressive gait deficits in idiopathic PD while ...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00372
更新日期：2019-05-14 00:00:00
abstract：:Apathy is pervasive across many neuropsychiatric disorders but is poorly characterized mechanistically, so targeted therapeutic interventions remain elusive. A key impediment has been the lack of validated assessment tools to facilitate translation of promising findings between preclinical disease models and patients....
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00858
更新日期：2019-08-09 00:00:00
abstract：:Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the characteristic loss of hand function and spoken language after the first year of life, people with RTT also have a variety of physiological and auton...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2020.593554
更新日期：2020-10-30 00:00:00
abstract：:Genetic findings of the past years have provided ample evidence for a substantial etiologic heterogeneity of dystonic syndromes. While an increasing number of genes are being identified for Mendelian forms of isolated and combined dystonias using classical genetic mapping and whole-exome sequencing techniques, their p...
journal_title：Frontiers in neurology
pub_type： 杂志文章,评审
doi：10.3389/fneur.2016.00241
更新日期：2017-01-16 00:00:00
abstract：:Objective: To assess the relation between a sum score of imaging markers indicative of cerebral amyloid angiopathy (CAA) and cognitive impairment, stroke, dementia, and mortality in a general population. Methods: One thousand six hundred twenty-two stroke-free and dementia-free participants of the population-based Rot...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.01276
更新日期：2019-12-06 00:00:00
abstract：:Cerebral cortical microinfarct (CMI) is common in patients with dementia and cognitive decline. Emerging studies reported that intestinal dysfunction influenced the outcome of ischemic stroke and that vagus nerve stimulation (VNS) protected against ischemic stroke. However, the effects of intestinal dysfunction and VN...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00798
更新日期：2018-09-26 00:00:00
abstract：:In order to better understand how to identify and treat student-athletes who experience concussions, better insight into reporting behavior of athletes is needed. This study aims to identify information influencing athletes' attitudes toward reporting their concussions and the perceived trajectory of their recovery bo...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00698
更新日期：2019-07-05 00:00:00
abstract：:Background: For the preoperatively often required confirmation of clinically defined carpal tunnel syndrome (CTS), sensory as well as motor nerve conduction studies can be applied. The aim of this study was to test the sensitivity of specific motor nerve conduction tests in comparison with, as well as in addition to, ...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2019.00149
更新日期：2019-03-14 00:00:00
abstract：:Traumatic brain injury (TBI) due to explosive blast exposure is a leading combat casualty. It is also implicated as a key contributor to war related mental health diseases. A clinically important consequence of all types of TBI is a high risk for development of seizures and epilepsy. Seizures have been reported in pat...
journal_title：Frontiers in neurology
pub_type： 杂志文章,评审
doi：10.3389/fneur.2014.00047
更新日期：2014-04-09 00:00:00
abstract：:Alzheimer's disease is the most common neurodegenerative form of dementia that steadily worsens and eventually leads to death. Its set of symptoms include loss of cognitive function and memory decline. Structural and functional imaging methods such as CT, MRI, and PET scans play an essential role in the diagnosis proc...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2017.00647
更新日期：2017-12-07 00:00:00
abstract：:Introduction: The recent publication of a trial failed to prove the efficacy of minimally invasive surgery (MIS) in patients with intracerebral hemorrhage. The aim of this study was to answer the question: Do we need more trials to compare MIS vs. conservative treatment in these patients? Methods: Databases were searc...
journal_title：Frontiers in neurology
pub_type：
doi：10.3389/fneur.2020.00426
更新日期：2020-06-04 00:00:00
abstract：Background:Visual impairment affects up to 70% of stroke survivors. We designed an app (StrokeVision) to facilitate screening for common post stroke visual issues (acuity, visual fields, and visual inattention). We sought to describe the test time, feasibility, acceptability, and accuracy of our app-based digital visua...
journal_title：Frontiers in neurology
pub_type： 杂志文章
doi：10.3389/fneur.2018.00146
更新日期：2018-03-28 00:00:00
