Photolysis of Caged-GABA Rapidly Terminates Seizures In Vivo: Concentration and Light Intensity Dependence.

abstract：:Therapeutic hypothermia (HT) is a currently accepted treatment for neonatal asphyxia and is a promising strategy in adult stroke therapy. We previously reported that acute administration of docosahexaenoic acid (DHA) triglyceride emulsion (tri-DHA) protects against hypoxic-ischemic (HI) injury in neonatal mice. We que...

journal_title：Frontiers in neurology

authors： Manual Kollareth DJ,Zirpoli H,Ten VS,Deckelbaum RJ

更新日期：2021-01-15 00:00:00

abstract：:Sleep complaints increase profoundly with age; prevalence estimates of insomnia in the elderly reach up to 37%. The three major types of nocturnal complaints are difficulties initiating (DIS) and maintaining (DMS) sleep and early morning awakening (EMA), of which the latter appears most characteristic for aging. The n...

journal_title：Frontiers in neurology

authors： Stoffers D,Moens S,Benjamins J,van Tol MJ,Penninx BW,Veltman DJ,Van der Wee NJ,Van Someren EJ

更新日期：2012-06-28 00:00:00

abstract：:Aim: The aim of the study was to investigate the effect of the onset of Parkinson's disease (PD) on life satisfaction. Method: Data from 2008, 2011, and 2014 were used from a population-based prospective cohort (German Ageing Survey; 8,982 observations in FE regression analysis) of community-residing individuals in th...

journal_title：Frontiers in neurology

authors： Buczak-Stec EW,König HH,Hajek A

更新日期：2018-07-25 00:00:00

abstract：:Background: Strokes have a huge impact on patients' quality of life. Although there are potentially effective secondary preventions and treatment options for stroke patients, adherence is mostly low. Low disease and treatment-related knowledge and, consequently, a lack of informed decision-making in stroke patients ma...

journal_title：Frontiers in neurology

authors： Alegiani AC,Rahn AC,Steckelberg A,Thomalla G,Heesen C,Köpke S

更新日期：2020-12-07 00:00:00

abstract：:Objective: As a recently defined disease entity, vestibular migraine (VM) is a variant of migraine with broad spectrum of manifestations. We evaluated a prospective cohort of patients with VM in two centers to assess severity of VM attacks and investigate its contributing factors in patients with VM. Methods: Adult pa...

journal_title：Frontiers in neurology

authors： Liu W,Dong H,Yang L,Zhao H,Dong W,Yang Y

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND AND PURPOSE:Cardiac myxoma is a rare etiology of stroke. Both cerebral microbleeds and cardiac myxoma may increase the risk of intracerebral hemorrhage after intravenous (IV) thrombolysis. However, data are still limited. We report a case of multiple cerebral microbleeds treated with IV thrombolysis with lat...

journal_title：Frontiers in neurology

authors： Chutinet A,Roongpiboonsopit D,Suwanwela NC

更新日期：2014-12-01 00:00:00

abstract：:Background: Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is one of the nine polyglutamine (polyQ) diseases and is caused by a CAG repeat expansion within the coding sequence of the ATXN3 gene. Few multimodal imaging analyses of the macro- and micro-structural changes have been performed. Methods: In...

journal_title：Frontiers in neurology

authors： Peng H,Liang X,Long Z,Chen Z,Shi Y,Xia K,Meng L,Tang B,Qiu R,Jiang H

更新日期：2019-09-24 00:00:00

abstract：:Different subtypes of Alzheimer's disease (AD) with characteristic distributions of neurofibrillary tangles and corresponding brain atrophy patterns have been identified using structural magnetic resonance imaging (MRI). However, the underlying biological mechanisms that determine this differential expression of neuro...

journal_title：Frontiers in neurology

authors： Ferreira D,Pereira JB,Volpe G,Westman E

更新日期：2019-05-28 00:00:00

abstract：PURPOSE:Traumatic brain injury involving loss of consciousness has focal effects in the human brainstem, suggesting that it may have particular consequences for eye movement control. This hypothesis was investigated by measurements of vergence eye movement parameters. METHODS:Disparity vergence eye movements were meas...

journal_title：Frontiers in neurology

authors： Tyler CW,Likova LT,Mineff KN,Elsaid AM,Nicholas SC

更新日期：2015-02-03 00:00:00

abstract：:Introduction: The purpose of this study was to verify whether the prevalence of intracranial aneurysm (IA) in patients with acoustic neuroma is greater than that in age- and sex-matched controls and to evaluate the independent risk factors related to the occurrence of IA. Methods: We retrospectively analyzed 231 patie...

journal_title：Frontiers in neurology

authors： You H,Bai Y,Yu T,Zeng T,Huang N,Mei W,Jiang C,Kang D,Wu X,Chen F

更新日期：2020-11-02 00:00:00

abstract：:Shame and embarrassment related to Parkinson's disease (PD) are rarely addressed in clinical practice nor studied in neuroscience research, partly because no specific tool exists to detect them in PD. Objective: To develop a self-applied assessment tool of shame and embarrassment specifically related to PD or its trea...

journal_title：Frontiers in neurology

authors： Fleury V,Catalano Chiuvé S,Forjaz MJ,Di Marco M,Messe M,Debove I,Angulo J,Hariz GM,Burkhard PR,Martinez-Martin P,Rodriguez-Blazquez C,Krack P

更新日期：2020-07-31 00:00:00

abstract：:Stroke is a leading cause of death and disability, and recombinant tissue plasminogen activator (rtPA) can significantly reduce the long-term impact of acute ischemic stroke (AIS) if given within 3 h of symptom onset. South Carolina is located in the "stroke belt" and has a high rate of stroke and stroke mortality. Ma...

journal_title：Frontiers in neurology

authors： Kazley AS,Wilkerson RC,Jauch E,Adams RJ

更新日期：2012-03-21 00:00:00

abstract：:Genetic findings of the past years have provided ample evidence for a substantial etiologic heterogeneity of dystonic syndromes. While an increasing number of genes are being identified for Mendelian forms of isolated and combined dystonias using classical genetic mapping and whole-exome sequencing techniques, their p...

journal_title：Frontiers in neurology

authors： Verbeek DS,Gasser T

更新日期：2017-01-16 00:00:00

abstract：CONTEXT:Mandibular movements (MM) are considered as reliable reporters of respiratory effort (RE) during sleep and sleep disordered breathing (SDB), but MM accuracy has never been validated against the gold standard diaphragmatic electromyography (EMG-d). OBJECTIVES:To assess the degree of agreement between MM and EMG...

journal_title：Frontiers in neurology

authors： Martinot JB,Le-Dong NN,Cuthbert V,Denison S,Silkoff PE,Guénard H,Gozal D,Pepin JL,Borel JC

更新日期：2017-07-21 00:00:00

abstract：:Background: Intracranial carotid artery calcification (ICAC) on computed tomography (CT) is a marker of atherosclerosis and an independent predictor of vascular events including stroke. While vitamin K antagonists (VKAs) are used to prevent embolic stroke, they have been shown to increase levels of both coronary and e...

journal_title：Frontiers in neurology

authors： Peeters MTJ,Houben R,Postma AA,van Oostenbrugge RJ,Schurgers LJ,Staals J

更新日期：2019-12-20 00:00:00

abstract：:Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores exists. This study examined several possible composite scores for the test battery used in the large...

journal_title：Frontiers in neurology

authors： Stenberg J,Karr JE,Terry DP,Saksvik SB,Vik A,Skandsen T,Silverberg ND,Iverson GL

更新日期：2020-07-17 00:00:00

abstract：:There is a need for biomarkers for amyotrophic lateral sclerosis (ALS), to support the diagnosis of the disease, to predict disease progression and to track disease activity and treatment responses. Over the last decade multiple studies have investigated the potential of neurofilament levels, both in cerebrospinal flu...

journal_title：Frontiers in neurology

authors： Poesen K,Van Damme P

更新日期：2019-01-18 00:00:00

abstract：:Background: Over the last few years there has been growing interest in use of visual measures as useful tools for multiple sclerosis (MS) prognosis and tracking. Optic neuritis (ON) being a prevalent and often-presenting symptom of the disease, as well as the high occurrence rate of posterior visual system damage inde...

journal_title：Frontiers in neurology

authors： Backner Y,Petrou P,Glick-Shames H,Raz N,Zimmermann H,Jost R,Scheel M,Paul F,Karussis D,Levin N

更新日期：2019-05-03 00:00:00

abstract：:Background: Interhospital transfer for endovascular treatment (EVT) within neurovascular networks might result in transfer of patients who will not undergo EVT (futile transfer). Limited evidence exists on factors associated with the primary patient selection for interhospital transfer from primary stroke centers (PSC...

journal_title：Frontiers in neurology

authors： Stefanou MI,Stadler V,Baku D,Hennersdorf F,Ernemann U,Ziemann U,Poli S,Mengel A

更新日期：2020-12-04 00:00:00

abstract：:Non-motor symptoms of Parkinson's disease (PD) have been receiving increasing attention. Approximately half of patients with PD have experience PD-related pain. We investigated the effect and mechanism of acupuncture in patients with PD who have pain. PD patients with pain were divided into acupuncture group and contr...

journal_title：Frontiers in neurology

authors： Yu SW,Lin SH,Tsai CC,Chaudhuri KR,Huang YC,Chen YS,Yeh BY,Wu YR,Wang JJ

更新日期：2019-10-22 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fneur.2019.00129.]. ...

journal_title：Frontiers in neurology

authors： Frontiers Production Office.

更新日期：2019-03-27 00:00:00

abstract：:The vestibular system plays a crucial role in maintaining postural balance. Unilateral vestibular lesions result in a typical syndrome characterized by postural imbalance, altered locomotor patterns and gaze stabilization, as well as cognitive and neurovegetative disorders. One of the main difficulties encountered in ...

journal_title：Frontiers in neurology

authors： Marouane E,Rastoldo G,El Mahmoudi N,Péricat D,Chabbert C,Artzner V,Tighilet B

更新日期：2020-05-29 00:00:00

abstract：:Background: Giant vertebrobasilar aneurysms (GVBAs) have an unfavorable natural history if left untreated and often pose a sizeable challenge to endovascular treatment. The aim of this study was to analyze the angiographic and clinical outcomes of GVBAs treated by various endovascular procedures. Methods: Between Janu...

journal_title：Frontiers in neurology

authors： Li M,Liang H,Wang J

更新日期：2020-08-11 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive therapy that has been implicated in treatment of serious neurological disorders. However, the neurobiological mechanisms underlying the effects of rTMS remain unclear. Therefore, this study examined the differential effects of repetitive magnetic st...

journal_title：Frontiers in neurology

authors： Baek A,Kim JH,Pyo S,Jung JH,Park EJ,Kim SH,Cho SR

更新日期：2018-02-13 00:00:00

abstract：:Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language su...

journal_title：Frontiers in neurology

authors： Liu X,He F,Chen Z,Liu P,Peng G

更新日期：2018-02-16 00:00:00

abstract：:Background: Using conventional visual evoked potentials (VEPs), migraine patients were found to be hyperresponsive to visual stimulus. Considering that a significant portion of neuronal activity is lost for analysis in the averaging process of conventional VEPs, in this study we investigated visual evoked responses of...

journal_title：Frontiers in neurology

authors： Lisicki M,D'Ostilio K,Coppola G,Maertens de Noordhout A,Parisi V,Schoenen J,Magis D

更新日期：2018-05-30 00:00:00

abstract：:With the demographic shift of the global population toward longer life expectancy, the number of people living with Alzheimer's disease (AD) has rapidly expanded and is projected to triple by the year 2050. Current treatments provide symptomatic relief but do not affect the underlying pathology of the disease. Therapi...

journal_title：Frontiers in neurology

authors： Ritter A,Cummings J

更新日期：2015-08-31 00:00:00

abstract：:Multiple sclerosis (MS) pathology progressively affects multiple central nervous system (CNS) areas. Due to this fact, MS produces a wide array of symptoms. Symptomatic therapy of one MS symptom can cause or worsen other unwanted symptoms (anticholinergics used for bladder dysfunction produce impairment of cognition, ...

journal_title：Frontiers in neurology

authors： Fernández Ó,Costa-Frossard L,Martínez-Ginés M,Montero P,Prieto JM,Ramió L

更新日期：2020-03-17 00:00:00

abstract：:α-synuclein is involved in the pathogenesis of multiple system atrophy (MSA) and can be regulated by peripheral immune activation (PIA). We aimed to clarify the correlations between PIA and the prevalence of MSA and to analyze the role of PIA in the progression of the disease. A total of 321 patients with probable MSA...

journal_title：Frontiers in neurology

authors： Cao B,Chen X,Zhang L,Wei Q,Liu H,Feng W,Chen Y,Shang H

更新日期：2020-07-07 00:00:00

abstract：:Studies of traumatic brain injury from all causes have found evidence of chronic hypopituitarism, defined by deficient production of one or more pituitary hormones at least 1 year after injury, in 25-50% of cases. Most studies found the occurrence of posttraumatic hypopituitarism (PTHP) to be unrelated to injury sever...

journal_title：Frontiers in neurology

authors： Wilkinson CW,Pagulayan KF,Petrie EC,Mayer CL,Colasurdo EA,Shofer JB,Hart KL,Hoff D,Tarabochia MA,Peskind ER

更新日期：2012-02-07 00:00:00