Cognitive, Emotional and Psychological Manifestations in Amyotrophic Lateral Sclerosis at Baseline and Overtime: A Review.

abstract：:The melanocortin receptors (MCRs) are a gene family in the rhodopsin class of G protein-coupled receptors. Based on the analysis of several metazoan genome databases it appears that the MCRs are only found in chordates. The presence of five genes in the family (i.e., mc1r, mc2r, mc3r, mc4r, mc5r) in representatives of...

journal_title：Frontiers in neuroscience

authors： Dores RM

更新日期：2013-04-10 00:00:00

abstract：:For brain-computer interfaces (BCIs) that utilize visual cues to direct the user, the neural signals extracted by the computer are representative of ongoing processes, visual evoked responses, and voluntary modulation. We proposed to use three brain signatures for predicting success on a single trial of a BCI task. Th...

journal_title：Frontiers in neuroscience

authors： Geronimo A,Kamrunnahar M,Schiff SJ

更新日期：2016-04-26 00:00:00

abstract：:It is necessary to understand the morphology of the vagus nerve (VN) to design and deliver effective and selective vagus nerve stimulation (VNS) because nerve morphology influences fiber responses to electrical stimulation. Specifically, nerve diameter (and thus, electrode-fiber distance), fascicle diameter, fascicula...

journal_title：Frontiers in neuroscience

authors： Pelot NA,Goldhagen GB,Cariello JE,Musselman ED,Clissold KA,Ezzell JA,Grill WM

更新日期：2020-11-04 00:00:00

abstract：:This study was designed to investigate the molecular mechanism of stroke and to explore the effect of miR-224-5p in hypoxic cortical neurons. Firstly, we established a middle cerebral artery occlusion (MCAO) model with Sprague-Dawley rats. Triphenyltetrazolium chloride (TTC) staining showed the brain infarction of an ...

journal_title：Frontiers in neuroscience

authors： Liu LL,Qiao S,Wang ML,Wu HK,Su YX,Wang KM,Liu XW

更新日期：2020-06-25 00:00:00

abstract：:Ischemic stroke places an increasing burden on individuals, families, and societies around the world. However, effective therapies or drugs for ischemic stroke are lacking. Therefore, animal models mimicking ischemic stroke in humans are of great value for preclinical experiments. middle cerebral artery occlusion (MCA...

journal_title：Frontiers in neuroscience

authors： Shi XF,Ai H,Lu W,Cai F

更新日期：2019-02-12 00:00:00

abstract：:Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by T helper (h)1 and/or Th17 CD4 T cells that drive inflammatory lesion development along with demyelination and neuronal damage. Defects in immune regulatory mechanisms are thought to play a role in the pathogenesis of MS. W...

journal_title：Frontiers in neuroscience

authors： Miller NM,Wang J,Tan Y,Dittel BN

更新日期：2015-08-18 00:00:00

abstract：:The mammalian brain is characterized by orderly spatial distribution of its cellular components, commonly referred to as topographical organization. The topography of cortical and subcortical maps is thought to represent functional or computational properties. In the present investigation, we have studied map transfor...

journal_title：Frontiers in neuroscience

authors： Leergaard TB,Bjaalie JG

更新日期：2007-10-15 00:00:00

abstract：:The recently renewed focus on the human exploration of outer space has boosted the interest toward a variety of questions regarding health of astronauts and cosmonauts. Among the others, sleep has traditionally been considered a central issue. To extend the research chances, human sleep alterations have been investiga...

journal_title：Frontiers in neuroscience

authors： Zivi P,De Gennaro L,Ferlazzo F

更新日期：2020-08-11 00:00:00

abstract：:Attention and working memory (WM) are core components of executive functions, and they can be enhanced by training. One activity that has shown to improve executive functions is musical training, but the brain networks underlying these improvements are not well known. We aimed to identify, using functional MRI (fMRI),...

journal_title：Frontiers in neuroscience

authors： Kausel L,Zamorano F,Billeke P,Sutherland ME,Larrain-Valenzuela J,Stecher X,Schlaug G,Aboitiz F

更新日期：2020-10-08 00:00:00

abstract：:Developments of new strategies to restore vision and improving on current strategies by harnessing new advancements in material and electrical sciences, and biological and genetic-based technologies are of upmost health priorities around the world. Federal and private entities are spending billions of dollars on visua...

journal_title：Frontiers in neuroscience

authors： Farnum A,Pelled G

更新日期：2020-02-18 00:00:00

abstract：:The advent of large scale neural computational platforms has highlighted the lack of algorithms for synthesis of neural structures to perform predefined cognitive tasks. The Neural Engineering Framework (NEF) offers one such synthesis, but it is most effective for a spike rate representation of neural information, and...

journal_title：Frontiers in neuroscience

authors： Tapson JC,Cohen GK,Afshar S,Stiefel KM,Buskila Y,Wang RM,Hamilton TJ,van Schaik A

更新日期：2013-08-30 00:00:00

abstract：:Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominant form of HSP, and ...

journal_title：Frontiers in neuroscience

authors： Napoli B,Gumeni S,Forgiarini A,Fantin M,De Filippis C,Panzeri E,Vantaggiato C,Orso G

更新日期：2019-11-19 00:00:00

abstract：:It is known that olfaction is essential for the occurrence of sexual behavior in male goldfish. Sex pheromones from ovulatory females elicit male sexual behavior, chasing, and sperm releasing act. In female goldfish, ovarian prostaglandin F2α (PGF) elicits female sexual behavior, egg releasing act. It has been conside...

journal_title：Frontiers in neuroscience

authors： Kawaguchi Y,Nagaoka A,Kitami A,Mitsuhashi T,Hayakawa Y,Kobayashi M

更新日期：2014-04-30 00:00:00

abstract：:Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for an (previously) orphan G-protein-coupled receptor (GPCR). They are multitasking peptides involved in many physiological functions, including regulation of feeding behavior, wakefulness and autonomic/neuroen...

journal_title：Frontiers in neuroscience

authors： Soya S,Sakurai T

更新日期：2020-07-10 00:00:00

abstract：Background:Non-invasive neuromodulation is an emerging therapy for children with early brain injury but is difficult to apply to preschoolers when windows of developmental plasticity are optimal. Transcranial static magnetic field stimulation (tSMS) decreases primary motor cortex (M1) excitability in adults but effects...

journal_title：Frontiers in neuroscience

authors： Hollis A,Zewdie E,Nettel-Aguirre A,Hilderley A,Kuo HC,Carlson HL,Kirton A

更新日期：2020-05-19 00:00:00

abstract：:Several works have demonstrated that visual experience plays a critical role in the development of allocentric spatial coding. Indeed, while children with a typical development start to code space by relying on allocentric landmarks from the first year of life, blind children remain anchored to an egocentric perspecti...

journal_title：Frontiers in neuroscience

authors： Martolini C,Cappagli G,Luparia A,Signorini S,Gori M

更新日期：2020-06-16 00:00:00

abstract：Objectives:Many post-traumatic patients with minimally conscious state are complicated by psychomotor inhibition state (PIS), which impedes further rehabilitation. The treatment of PIS is not satisfactory. This pilot study aimed to investigate effects of anodal transcranial direct current stimulation (A-tDCS) on PIS in...

journal_title：Frontiers in neuroscience

authors： Zhang X,Liu B,Li N,Li Y,Hou J,Duan G,Wu D

更新日期：2020-05-20 00:00:00

abstract：:Mu/beta rhythms are well-studied brain activities that originate from sensorimotor cortices. These rhythms reveal spectral changes in alpha and beta bands induced by movements of different body parts, e.g., hands and limbs, in electroencephalography (EEG) signals. However, less can be revealed in them about movements ...

journal_title：Frontiers in neuroscience

authors： Xiao R,Ding L

更新日期：2015-09-01 00:00:00

abstract：:Concerns regarding a drought in psychopharmacology have risen from many quarters. From one perspective, the wellspring of bedrock medications for anxiety disorders, depression, and schizophrenia was serendipitously discovered over 30 year ago, the swell of pharmaceutical investment in drug discovery has receded, and t...

journal_title：Frontiers in neuroscience

authors： Macdonald K,Feifel D

更新日期：2013-03-15 00:00:00

abstract：:Selection of the time-window mainly affects the effectiveness of piecewise feature extraction procedures. We present an enhanced bag-of-patterns representation that allows capturing the higher-level structures of brain dynamics within a wide window range. So, we introduce augmented instance representations with extend...

journal_title：Frontiers in neuroscience

authors： Collazos-Huertas D,Caicedo-Acosta J,Castaño-Duque GA,Acosta-Medina CD

更新日期：2020-02-25 00:00:00

abstract：Objective:Magnetic resonance-guided focused ultrasound surgery (MRgFUS) lesioning is a new treatment for brain disorders. However, the skull is a major barrier of ultrasound sonication in MRgFUS because it has an irregular surface and varies its size and shape among individuals. We recently developed the concept of sku...

journal_title：Frontiers in neuroscience

authors： Chang KW,Rachmilevitch I,Chang WS,Jung HH,Zadicario E,Prus O,Chang JW

更新日期：2021-01-12 00:00:00

abstract：:The motor neuron degenerative disease spinal muscular atrophy (SMA) remains one of the most frequently inherited causes of infant mortality. Afflicted patients loose the survival motor neuron 1 (SMN1) gene but retain one or more copies of SMN2, a homolog that is incorrectly spliced. Primary treatment strategies for SM...

journal_title：Frontiers in neuroscience

authors： Borg R,Cauchi RJ

更新日期：2014-10-15 00:00:00

abstract：:Quality assessment of diffusion MRI (dMRI) data is essential prior to any analysis, so that appropriate pre-processing can be used to improve data quality and ensure that the presence of MRI artifacts do not affect the results of subsequent image analysis. Manual quality assessment of the data is subjective, possibly ...

journal_title：Frontiers in neuroscience

authors： Samani ZR,Alappatt JA,Parker D,Ismail AAO,Verma R

更新日期：2020-01-22 00:00:00

abstract：:Antipsychotic drugs (APDs) are widely prescribed to control various mental disorders. As mental disorders are chronic diseases, these drugs are often used over a life-time. However, APDs can cause serious glucometabolic side-effects including type 2 diabetes and hyperglycaemic emergency, leading to medication non-comp...

journal_title：Frontiers in neuroscience

authors： Chen J,Huang XF,Shao R,Chen C,Deng C

更新日期：2017-11-21 00:00:00

abstract：:Background: The relationship between awareness and attention is complex and controversial. A growing body of literature has shown that the neural bases of consciousness and endogenous attention (voluntary attention) are independent. The important role of exogenous attention (reflexive attention) on conscious experienc...

journal_title：Frontiers in neuroscience

authors： Chen Y,Wang X,Yu Y,Liu Y

更新日期：2017-11-13 00:00:00

abstract：:The enteric glia, a neural crest-derived cell type that composes the Enteric Nervous System, is involved in controlling gut functions, including motility, gut permeability, and neuronal communication. Moreover this glial cell could to give rise to new neurons. It is believed that enteric neurons are generated up to 21...

journal_title：Frontiers in neuroscience

authors： Veríssimo CP,Carvalho JDS,da Silva FJM,Campanati L,Moura-Neto V,Coelho-Aguiar JM

更新日期：2019-09-03 00:00:00

abstract：:Previous studies have demonstrated that total flavonoid extracts from Caragana sinica (TFC) exert multiple therapeutic effects, promote blood flow, and exhibit anti-inflammatory and antioxidant properties. The present study aimed to investigate whether TFC promotes angiogenesis and exerts neuroprotective effects in a ...

journal_title：Frontiers in neuroscience

authors： He Q,Li S,Li L,Hu F,Weng N,Fan X,Kuang S

更新日期：2018-09-12 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs), also known as NG2 glia, arise from neural progenitor cells in the embryonic ganglionic eminences that also generate inhibitory neurons. They are ubiquitously distributed in the central nervous system, remain proliferative through life, and generate oligodendrocytes in both gray ...

journal_title：Frontiers in neuroscience

authors： Boshans LL,Factor DC,Singh V,Liu J,Zhao C,Mandoiu I,Lu QR,Casaccia P,Tesar PJ,Nishiyama A

更新日期：2019-08-08 00:00:00

abstract：:Opioid abuse is now the primary cause of accidental deaths in the United States. Studies over several decades established the cyclical nature of abused drugs of choice, with a current resurgence of heroin abuse and, more recently, fentanyl's emergence as a major precipitant of drug-related deaths. To better understand...

journal_title：Frontiers in neuroscience

authors： Saad MH,Savonen CL,Rumschlag M,Todi SV,Schmidt CJ,Bannon MJ

更新日期：2018-10-23 00:00:00

abstract：:Amputation of a sensory peripheral nerve induces severe anatomical and functional changes along the afferent pathway as well as perception alterations and neuropathic pain. In previous studies we showed that electrical stimulation applied to a transected infraorbital nerve protects the somatosensory cortex from the ab...

journal_title：Frontiers in neuroscience

authors： Virtuoso A,Herrera-Rincon C,Papa M,Panetsos F

更新日期：2019-05-01 00:00:00