MiR224-5p Inhibitor Restrains Neuronal Apoptosis by Targeting NR4A1 in the Oxygen-Glucose Deprivation (OGD) Model.

abstract：:The functional characterization of crustacean neuropeptides and their cognate receptors has not kept pace with the recent advances in sequence determination and, therefore, our understanding of the physiological roles of neuropeptides in this important arthropod sub-phylum is rather limited. We identified a candidate ...

journal_title：Frontiers in neuroscience

authors： Alexander J,Oliphant A,Wilcockson DC,Webster SG

更新日期：2018-07-04 00:00:00

abstract：:Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity. However, in a number of neurodegenerative diseases, including Alzheimer's disease (AD), tau undergoes pathological modifications i...

journal_title：Frontiers in neuroscience

authors： Pérez MJ,Jara C,Quintanilla RA

更新日期：2018-07-05 00:00:00

abstract：:Here, we present the first description of an isolation syndrome in a patient who suffered prolonged cardiac arrest and underwent a standard therapeutic hypothermia protocol. Two years after the arrest, the patient demonstrated no motor responses to commands, communication capabilities, or visual tracking at the bedsid...

journal_title：Frontiers in neuroscience

authors： Forgacs PB,Fridman EA,Goldfine AM,Schiff ND

更新日期：2016-06-09 00:00:00

abstract：:The structural organization of cortical areas is not random, with topographic maps commonplace in sensory processing centers. This topographical organization allows optimal wiring between neurons, multimodal sensory integration, and performs input dimensionality reduction. In this work, a model of topographic map form...

journal_title：Frontiers in neuroscience

authors： Bogdan PA,Rowley AGD,Rhodes O,Furber SB

更新日期：2018-07-02 00:00:00

abstract：:Despite evolutionary musicology's interdisciplinary nature, and the diverse methods it employs, the field has nevertheless tended to divide into two main positions. Some argue that music should be understood as a naturally selected adaptation, while others claim that music is a product of culture with little or no rel...

journal_title：Frontiers in neuroscience

authors： van der Schyff D,Schiavio A

更新日期：2017-09-29 00:00:00

abstract：:Throughout the past decade, silicon-based neural probes have become a driving force in neural engineering. Such probes comprise sophisticated, integrated CMOS electronics which provide a large number of recording sites along slender probe shanks. Using such neural probes in a chronic setting often requires them to be ...

journal_title：Frontiers in neuroscience

authors： Chauvière L,Pothof F,Gansel KS,Klon-Lipok J,Aarts AAA,Holzhammer T,Paul O,Singer WJ,Ruther P

更新日期：2019-05-21 00:00:00

abstract：:An associative brain-computer-interface (BCI) that correlates in time a peripherally generated afferent volley with the peak negativity (PN) of the movement related cortical potential (MRCP) induces plastic changes in the human motor cortex. However, in this associative BCI the movement timed to a cue is not detected ...

journal_title：Frontiers in neuroscience

authors： Mrachacz-Kersting N,Aliakbaryhosseinabadi S

更新日期：2018-07-11 00:00:00

abstract：:Neurons are generated during embryonic development and in adulthood, although adult neurogenesis is restricted to two main brain regions, the hippocampus and olfactory bulb. The subventricular zone (SVZ) of the lateral ventricles generates neural stem/progenitor cells that continually provide the olfactory bulb (OB) w...

journal_title：Frontiers in neuroscience

authors： Figueres-Oñate M,López-Mascaraque L

更新日期：2016-05-09 00:00:00

abstract：:The diterpenoid compound, Oridonin, extracted from the Chinese herb, Rabdosia rubescens, possesses multiple biological activities and properties. Oridonin exhibited efficient anti-inflammatory activity by inducing a switch in macrophage polarization to the anti-inflammatory phenotype through inhibition of the Notch pa...

journal_title：Frontiers in neuroscience

authors： Xu L,Li L,Zhang CY,Schluesener H,Zhang ZY

更新日期：2019-04-02 00:00:00

abstract：:In this paper, we introduce a novel automatic method for Corpus Callosum (CC) in midsagittal plane segmentation. The robust segmentation of CC in midsagittal plane is key role for quantitative study of structural features of CC associated with various neurological disorder such as epilepsy, autism, Alzheimer's disease...

journal_title：Frontiers in neuroscience

authors： Park G,Kwak K,Seo SW,Lee JM

更新日期：2018-09-11 00:00:00

abstract：:[This corrects the article on p. 560 in vol. 10, PMID: 28008304.]. ...

journal_title：Frontiers in neuroscience

authors： Muñoz-Moreno E,Fischi-Gomez E,Batalle D,Borradori-Tolsa C,Eixarch E,Thiran JP,Gratacós E,Hüppi PS

更新日期：2017-05-09 00:00:00

abstract：:There has been evidence that during brain development, emerging thalamocortical (TC) and corticothalamic (CT) pathways converge in some brain regions and follow each other's trajectories to their final destinations. Corpus callosal (CC) pathways also emerge at a similar developmental stage, and are known to converge w...

journal_title：Frontiers in neuroscience

authors： Wang R,Wilkinson M,Kane T,Takahashi E

更新日期：2017-11-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive brain disorder with gradual memory loss that correlates to cognitive deficits in the elderly population. Recent studies have shown the potentials of machine learning algorithms to identify biomarkers and functional brain activity patterns across various AD stages using electro...

journal_title：Frontiers in neuroscience

authors： Fan M,Yang AC,Fuh JL,Chou CA

更新日期：2018-10-04 00:00:00

abstract：:The visual system is organized in a parallel and hierarchical architecture. However, the plasticity in hierarchical neural networks is controversial across different response features and at different levels. In this study, we recorded areas 17 and 21a, earlier and intermediate stages of the visual cortex in the cat, ...

journal_title：Frontiers in neuroscience

authors： Wang J,Ni Z,Jin A,Yu T,Yu H

更新日期：2019-10-11 00:00:00

abstract：:Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH). However, comprehensive quantification of the oxylipin profile in ICH remains unknown. Therefore, an ICH mouse model was constru...

journal_title：Frontiers in neuroscience

authors： Yuan JJ,Chen Q,Xiong XY,Zhang Q,Xie Q,Huang JC,Yang GQ,Gong CX,Qiu ZM,Sang HF,Zi WJ,He Q,Xu R,Yang QW

更新日期：2020-09-23 00:00:00

abstract：:There is increasing evidence that metabolic dysfunction plays an important role in Alzheimer's disease (AD). Brain insulin resistance and subsequent impairment of insulin and insulin-like growth factor (IGF) signaling are associated with the neurodegenerative and clinical features of AD. Nevertheless, how the brain in...

journal_title：Frontiers in neuroscience

authors： Bonham LW,Geier EG,Steele NZR,Holland D,Miller BL,Dale AM,Desikan RS,Yokoyama JS,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2018-07-16 00:00:00

abstract：:Ongoing brain activity has been implicated in the modulation of cortical excitability. The combination of electroencephalography (EEG) and transcranial magnetic stimulation (TMS) in a real-time triggered setup is a novel method for testing hypotheses about the relationship between spontaneous neuronal oscillations, co...

journal_title：Frontiers in neuroscience

authors： Schaworonkow N,Caldana Gordon P,Belardinelli P,Ziemann U,Bergmann TO,Zrenner C

更新日期：2018-12-13 00:00:00

abstract：Background:Endovascular treatment of large or giant non-saccular vertebrobasilar aneurysms (VBAs) by conventional stents is difficult and has unsatisfactory outcomes. Object:This study was performed to retrospectively analyze the safety and efficacy of a flow diverter in treating large and giant non-saccular VBAs. Me...

journal_title：Frontiers in neuroscience

authors： Wang J,Jia L,Duan Z,Wang Z,Yang X,Zhang Y,Lv M

更新日期：2019-11-28 00:00:00

abstract：:Recent increases in attention deficit hyperactivity disorder (ADHD) diagnoses, and the escalation of stimulant prescriptions, has raised concern about diversion and abuse of stimulants, as well as the ethics of using these drugs as "cognitive enhancers."Such concern appears misplaced in the face of substantial evidenc...

journal_title：Frontiers in neuroscience

authors： Advokat C,Scheithauer M

更新日期：2013-05-29 00:00:00

abstract：:Aging is a complex natural phenomenon that is manifested by degenerative changes in the structure and function of cells and tissues. D-Galactose-induced aging mice are an artificial accelerated aging model that causes memory and learning impairment, oxidative stress, and neuroinflammation. In this study, we examined t...

journal_title：Frontiers in neuroscience

authors： Li H,Zheng L,Chen C,Liu X,Zhang W

更新日期：2019-09-18 00:00:00

abstract：:Neurodegenerative diseases are a challenge for drug discovery, as the biological mechanisms are complex and poorly understood, with a paucity of models that faithfully recapitulate these disorders. Recent advances in stem cell technology have provided a paradigm shift, providing researchers with tools to generate huma...

journal_title：Frontiers in neuroscience

authors： Han C,Chaineau M,Chen CX,Beitel LK,Durcan TM

更新日期：2018-02-06 00:00:00

abstract：:Opioid abuse is now the primary cause of accidental deaths in the United States. Studies over several decades established the cyclical nature of abused drugs of choice, with a current resurgence of heroin abuse and, more recently, fentanyl's emergence as a major precipitant of drug-related deaths. To better understand...

journal_title：Frontiers in neuroscience

authors： Saad MH,Savonen CL,Rumschlag M,Todi SV,Schmidt CJ,Bannon MJ

更新日期：2018-10-23 00:00:00

abstract：:Inhibitory control, the ability to suppress an immediate dominant response, has been shown to predict academic and career success, socioemotional wellbeing, wealth, and physical health. Learning to play a musical instrument engages various sensorimotor processes and draws on cognitive capacities including inhibition a...

journal_title：Frontiers in neuroscience

authors： Hennessy SL,Sachs ME,Ilari B,Habibi A

更新日期：2019-10-16 00:00:00

abstract：:We present a novel assistive control strategy for a robotic hip exoskeleton for assisting hip flexion/extension, based on a proportional Electromyography (EMG) strategy. The novelty of the proposed controller relies on the use of the Gastrocnemius Medialis (GM) EMG signal instead of a hip flexor muscle, to control the...

journal_title：Frontiers in neuroscience

authors： Grazi L,Crea S,Parri A,Molino Lova R,Micera S,Vitiello N

更新日期：2018-02-14 00:00:00

abstract：:A new paradigm in neuroscience has recently emerged - the brain-gut axis (BGA). The contemporary focus in this paradigm has been gut → brain ("bottom-up"), in which the gut-microbiome, and its perturbations, affects one's psychological state-of-mind and behavior, and is pivotal in neurodegenerative disorders. The emer...

journal_title：Frontiers in neuroscience

authors： Isaiah S,Loots DT,Solomons R,van der Kuip M,Tutu Van Furth AM,Mason S

更新日期：2020-04-21 00:00:00

abstract：:The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development, and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction, and other behaviors and it...

journal_title：Frontiers in neuroscience

authors： Beretta CA,Dross N,Guiterrez-Triana JA,Ryu S,Carl M

更新日期：2012-04-23 00:00:00

abstract：Purpose:To evaluate the effect of resolution on iron content using quantitative susceptibility mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in evaluating the iron content of deep gray matter (DGM) of the human brain using subjects from multiple sites; and to establish a susce...

journal_title：Frontiers in neuroscience

authors： Li Y,Sethi SK,Zhang C,Miao Y,Yerramsetty KK,Palutla VK,Gharabaghi S,Wang C,He N,Cheng J,Yan F,Haacke EM

更新日期：2021-01-06 00:00:00

abstract：:Prior research has shown that during development, there is increased segregation between, and increased integration within, prototypical resting-state functional brain networks. Functional networks are typically defined by static functional connectivity over extended periods of rest. However, little is known about how...

journal_title：Frontiers in neuroscience

authors： Rosenberg BM,Mennigen E,Monti MM,Kaiser RH

更新日期：2020-12-08 00:00:00

abstract：:We used amyotrophic lateral sclerosis (ALS) as a model of prefrontal dysfunction in order to re-assess the potential neuronal substrates of two sub processes of working memory, namely information storage and filtering. To date it is unclear which exact neuronal networks sustain these two processes and the prefrontal c...

journal_title：Frontiers in neuroscience

authors： Vellage AK,Veit M,Kobeleva X,Petri S,Vielhaber S,Müller NG

更新日期：2016-04-19 00:00:00

abstract：:Early detection of movement intention could possibly minimize the delays in the activation of neuroprosthetic devices. As yet, single trial analysis using non-invasive approaches for understanding such movement preparation remains a challenging task. We studied the feasibility of predicting movement directions in self...

journal_title：Frontiers in neuroscience

authors： Lew EY,Chavarriaga R,Silvoni S,Millán Jdel R

更新日期：2014-08-01 00:00:00