Functional Segregation of Human Brain Networks Across the Lifespan: An Exploratory Analysis of Static and Dynamic Resting-State Functional Connectivity.

abstract：:Adult neural stem cells (NSCs) are perceived as a homogeneous population of cells that divide infrequently and are capable of multi-lineage differentiation. However, recent data revealed that independent stem cell lineages act in parallel to maintain neurogenesis and provide a cellular source for tissue repair. In add...

journal_title：Frontiers in neuroscience

authors： Giachino C,Taylor V

更新日期：2014-02-25 00:00:00

abstract：:Recent studies have shown the ability to record high-γ signals (80-160 Hz) in electroencephalogram (EEG) from traumatic brain injury (TBI) patients who have had hemicraniectomies. However, extraction of the movement-related high-γ remains challenging due to a confounding bandwidth overlap with surface electromyogram (...

journal_title：Frontiers in neuroscience

authors： Li Y,Wang PT,Vaidya MP,Flint RD,Liu CY,Slutzky MW,Do AH

更新日期：2020-11-24 00:00:00

abstract：:Calcium imaging using fluorescent reporters is the most widely used optical approach to investigate activity in intact neuronal circuits with single-cell resolution. Calcium signals, however, are often difficult to interpret, especially if the desired output quantity is membrane voltage or instantaneous firing rates. ...

journal_title：Frontiers in neuroscience

authors： Moreaux L,Laurent G

更新日期：2008-12-15 00:00:00

abstract：:The motor neuron degenerative disease spinal muscular atrophy (SMA) remains one of the most frequently inherited causes of infant mortality. Afflicted patients loose the survival motor neuron 1 (SMN1) gene but retain one or more copies of SMN2, a homolog that is incorrectly spliced. Primary treatment strategies for SM...

journal_title：Frontiers in neuroscience

authors： Borg R,Cauchi RJ

更新日期：2014-10-15 00:00:00

abstract：:Developing new standardized tools to characterize brain recording devices is critical to evaluate neural probes and for translation to clinical use. The signal-to-noise ratio (SNR) measurement is the gold standard for quantifying the performance of brain recording devices. Given the drawbacks with the SNR measure, our...

journal_title：Frontiers in neuroscience

authors： Suarez-Perez A,Gabriel G,Rebollo B,Illa X,Guimerà-Brunet A,Hernández-Ferrer J,Martínez MT,Villa R,Sanchez-Vives MV

更新日期：2018-11-29 00:00:00

abstract：:Disruption of iron homeostasis and increased glial response are known to occur in brains afflicted by Alzheimer's disease (AD). While the APP/PS1 transgenic mouse model recapitulates the hallmark amyloid-beta plaque pathology of AD, it does so in a different neuronal mileu than humans. Understanding the iron character...

journal_title：Frontiers in neuroscience

authors： Meadowcroft MD,Connor JR,Yang QX

更新日期：2015-07-23 00:00:00

abstract：:Mu/beta rhythms are well-studied brain activities that originate from sensorimotor cortices. These rhythms reveal spectral changes in alpha and beta bands induced by movements of different body parts, e.g., hands and limbs, in electroencephalography (EEG) signals. However, less can be revealed in them about movements ...

journal_title：Frontiers in neuroscience

authors： Xiao R,Ding L

更新日期：2015-09-01 00:00:00

abstract：:Abnormal accumulation of TAR DNA-binding protein 43 (TDP-43) in the cytoplasm and its disappearance from the nucleus are pathological features of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) and are directly involved in the pathogenesis of these conditions. TDP-43 is an essential nuclear protein...

journal_title：Frontiers in neuroscience

authors： Sugai A,Kato T,Koyama A,Koike Y,Kasahara S,Konno T,Ishihara T,Onodera O

更新日期：2018-02-01 00:00:00

abstract：:Induction of lordosis as typical female sexual behavior in rodents is dependent on a mount stimulus from males and blood levels of estrogen. Periaqueductal gray (PAG) efferent neurons have been suggested to be important for lordosis behavior; however, the neurochemical basis remains to be understood. In this study, we...

journal_title：Frontiers in neuroscience

authors： Yamada S,Kawata M

更新日期：2014-12-18 00:00:00

abstract：:Accuracy in auditory distance perception can improve with practice and varies for sounds differing in familiarity. Here, listeners were trained to judge the distances of English, Bengali, and backwards speech sources pre-recorded at near (2-m) and far (30-m) distances. Listeners' accuracy was tested before and after t...

journal_title：Frontiers in neuroscience

authors： Wisniewski MG,Mercado E 3rd,Church BA,Gramann K,Makeig S

更新日期：2014-12-09 00:00:00

abstract：:Cochlear implantation constitutes a successful therapy of inner ear deafness, with the majority of patients showing good outcomes. There is, however, still some unexplained variability in outcomes with a number of cochlear-implant (CI) users, showing major limitations in speech comprehension. The current study used a ...

journal_title：Frontiers in neuroscience

authors： Kessler M,Schierholz I,Mamach M,Wilke F,Hahne A,Büchner A,Geworski L,Bengel FM,Sandmann P,Berding G

更新日期：2020-08-11 00:00:00

abstract：:In patients with impaired liver function and hepatic encephalopathy (HE), consistent elevations of blood ammonia concentration suggest a crucial role in the pathogenesis of HE. Ammonia and acetate are metabolized in brain both primarily in astrocytes. Here, we used dynamic [(11)C]acetate PET of the brain to measure th...

journal_title：Frontiers in neuroscience

authors： Iversen P,Mouridsen K,Hansen MB,Jensen SB,Sørensen M,Bak LK,Waagepetersen HS,Schousboe A,Ott P,Vilstrup H,Keiding S,Gjedde A

更新日期：2014-11-03 00:00:00

abstract：:Investigation into the neural and computational bases of decision-making has proceeded in two parallel but distinct streams. Perceptual decision-making (PDM) is concerned with how observers detect, discriminate, and categorize noisy sensory information. Economic decision-making (EDM) explores how options are selected ...

journal_title：Frontiers in neuroscience

authors： Summerfield C,Tsetsos K

更新日期：2012-05-24 00:00:00

abstract：:Openness to experience (OTE) has relatively stable and heritable characteristics. Previous studies have used candidate gene approaches to explore the genetic mechanisms of OTE, but genome-wide polygenic scores have a greater genetic effect than other genetic analysis methods, and previous studies have never examined t...

journal_title：Frontiers in neuroscience

authors： Ren Z,Liu C,Meng J,Liu Q,Shi L,Wu X,Song L,Qiu J

更新日期：2021-01-11 00:00:00

abstract：:We previously demonstrated that, in the early stages of tau processing in Alzheimer's disease, the N-terminal part of the molecule undergoes a characteristic cascade of phosphorylation and progressive misfolding of the proteins resulting in a structural conformation detected by Alz-50. In this immunohistochemical stud...

journal_title：Frontiers in neuroscience

authors： Flores-Rodríguez P,Ontiveros-Torres MA,Cárdenas-Aguayo MC,Luna-Arias JP,Meraz-Ríos MA,Viramontes-Pintos A,Harrington CR,Wischik CM,Mena R,Florán-Garduño B,Luna-Muñoz J

更新日期：2015-02-11 00:00:00

abstract：Introduction:Optical coherence tomography angiography (OCT-A) is a novel diagnostic tool with increasing applications in ophthalmology clinics that provides non-invasive high-resolution imaging of the retinal microvasculature. Our aim is to report in detail an experimental protocol for analyzing both vasodilatory and v...

journal_title：Frontiers in neuroscience

authors： Sousa DC,Leal I,Moreira S,do Vale S,Silva-Herdade AS,Aguiar P,Dionísio P,Abegão Pinto L,Castanho MARB,Marques-Neves C

更新日期：2019-06-12 00:00:00

abstract：:The Ossification of the Posterior Longitudinal Ligament (OPLL) is an idiopathic degenerative spinal disease which may cause motor deficit. For patients presenting myelopathy or severe stenosis, surgical decompression is the treatment of choice; however, despite adequate decompression residual motor impairment is found...

journal_title：Frontiers in neuroscience

authors： Puentes S,Kadone H,Kubota S,Abe T,Shimizu Y,Marushima A,Sankai Y,Yamazaki M,Suzuki K

更新日期：2018-03-02 00:00:00

abstract：:Tinnitus is unusual for such a common symptom in that there are few treatment options and those that are available are aimed at reducing the impact rather than specifically addressing the tinnitus percept. In particular, there is no drug recommended specifically for the management of tinnitus. Whilst some of the curre...

journal_title：Frontiers in neuroscience

authors： McFerran DJ,Stockdale D,Holme R,Large CH,Baguley DM

更新日期：2019-08-06 00:00:00

abstract：:Neurofibrillary pathology comprised of pathological tau protein is closely tied to a range of neurodegenerative disorders, the most common of which is Alzheimer's disease. While they are individually rarer, a range of other disorders, the tauopathies (including Pick's disease, progressive supranuclear palsy, corticoba...

journal_title：Frontiers in neuroscience

authors： Novak P,Kontsekova E,Zilka N,Novak M

更新日期：2018-11-02 00:00:00

abstract：:Silymarin is a bioactive constituent isolated from milk thistle (Silybum marinum). Since its discovery, silymarin has been considered a gold standard drug in treating ailments related to the liver, resulting from alcohol consumption and viral hepatitis. This hepatoprotective nature of silymarin arises out of antioxida...

journal_title：Frontiers in neuroscience

authors： Rathore P,Arora I,Rastogi S,Akhtar M,Singh S,Samim M

更新日期：2020-10-26 00:00:00

abstract：:Despite evolutionary musicology's interdisciplinary nature, and the diverse methods it employs, the field has nevertheless tended to divide into two main positions. Some argue that music should be understood as a naturally selected adaptation, while others claim that music is a product of culture with little or no rel...

journal_title：Frontiers in neuroscience

authors： van der Schyff D,Schiavio A

更新日期：2017-09-29 00:00:00

abstract：:Alzheimer's dementia commonly impacts the health of older adults and lacks any preventative therapy. While Alzheimer's dementia risk has a substantial genetic component, the specific molecular mechanisms and neuropathologies triggered by most of the known genetic variants are unclear. Resultantly, they have shown limi...

journal_title：Frontiers in neuroscience

authors： Tasaki S,Gaiteri C,Mostafavi S,De Jager PL,Bennett DA

更新日期：2018-10-08 00:00:00

abstract：:The neuropeptide gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Vertebrates possess multiple GnRH forms that are classified into three main groups, namely GnRH1, GnRH2, and GnRH3. In order to gain more insights into the GnRH gene family in vertebrates, we sought...

journal_title：Frontiers in neuroscience

authors： Gaillard AL,Tay BH,Pérez Sirkin DI,Lafont AG,De Flori C,Vissio PG,Mazan S,Dufour S,Venkatesh B,Tostivint H

更新日期：2018-09-06 00:00:00

abstract：:Obesity continues to be one of the major public health problems due to its high prevalence and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but also mood and cognitive disorders. Obese subjects often show deficits in memory, learning and executive functions compared to normal weight...

journal_title：Frontiers in neuroscience

authors： Agustí A,García-Pardo MP,López-Almela I,Campillo I,Maes M,Romaní-Pérez M,Sanz Y

更新日期：2018-03-16 00:00:00

abstract：:Up to now relatively little is known about interlimb reflexes (ILR). Especially it is not well known whether ILR may habituate or not to subsequent stimuli. The main aim of the present investigation was to explore the short term habituation behavior of ILR. The electromyogram was recorded over the tonically active bic...

journal_title：Frontiers in neuroscience

authors： Alaid S,Emmer A,Kornhuber ME

更新日期：2019-10-23 00:00:00

abstract：:Background: Gambling disorder (GD) is the most common behavioral addiction and shares pathophysiological and clinical features with substance use disorders (SUDs). Effective therapeutic interventions for GD are lacking. Non-invasive brain stimulation (NIBS) may represent a promising treatment option for GD. Objective:...

journal_title：Frontiers in neuroscience

authors： Zucchella C,Mantovani E,Federico A,Lugoboni F,Tamburin S

更新日期：2020-08-18 00:00:00

abstract：:Cerebral function is associated with exceptionally high metabolic activity, and requires continuous supply of oxygen and nutrients from the blood stream. Since the mid-twentieth century the idea that brain energy metabolism is coupled to neuronal activity has emerged, and a number of studies supported this hypothesis....

journal_title：Frontiers in neuroscience

authors： Sonnay S,Gruetter R,Duarte JMN

更新日期：2017-05-26 00:00:00

abstract：:Animals must routinely deal with barriers as they move through their natural environment. These challenges require directed changes in leg movements and posture performed in the context of ever changing internal and external conditions. In particular, cockroaches use a combination of tactile and visual information to ...

journal_title：Frontiers in neuroscience

authors： Ritzmann RE,Harley CM,Daltorio KA,Tietz BR,Pollack AJ,Bender JA,Guo P,Horomanski AL,Kathman ND,Nieuwoudt C,Brown AE,Quinn RD

更新日期：2012-07-06 00:00:00

abstract：:Platelet-rich plasma (PRP) is prepared by centrifuging fresh blood in an anticoagulant state, and harvesting the platelet-rich portion or condensing platelets. Studies have consistently demonstrated that PRP concentrates are an abundant source of growth factors, such as platelet-derived growth factor (PDGF), transform...

journal_title：Frontiers in neuroscience

authors： Chen NF,Sung CS,Wen ZH,Chen CH,Feng CW,Hung HC,Yang SN,Tsui KH,Chen WF

更新日期：2018-04-23 00:00:00

abstract：:Brain-computer interfaces (BCIs), independent of the brain's normal output pathways, are attracting an increasing amount of attention as devices that extract neural information. As a typical type of BCI system, the steady-state visual evoked potential (SSVEP)-based BCIs possess a high signal-to-noise ratio and informa...

journal_title：Frontiers in neuroscience

authors： Zhao Y,Tang J,Cao Y,Jiao X,Xu M,Zhou P,Ming D,Qi H

更新日期：2018-02-15 00:00:00