Topography of the complete corticopontine projection: from experiments to principal Maps.

abstract：:Protein homeostasis (proteostasis) requires the timely degradation of misfolded proteins and their aggregates by protein quality control (PQC), of which molecular chaperones are an essential component. Compared with other cell types, PQC in neurons is particularly challenging because they have a unique cellular struct...

journal_title：Frontiers in neuroscience

authors： Ciechanover A,Kwon YT

更新日期：2017-04-06 00:00:00

abstract：:The cocaine- and amphetamine-regulated transcript (CART) has been the subject of significant interest for over a decade. Work to decipher the detailed mechanism of CART function has been hampered by the lack of specific pharmacological tools like antagonists and the absence of a specific CART receptor(s). However, ext...

journal_title：Frontiers in neuroscience

authors： Lau J,Herzog H

更新日期：2014-10-13 00:00:00

abstract：:Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders entailing social and cognitive deficits, including marked problems with language. Numerous genes have been associated with ASD, but it is unclear how language deficits arise from gene mutation or dysregulation. It is also unclear why ASD shows ...

journal_title：Frontiers in neuroscience

authors： Benítez-Burraco A,Lattanzi W,Murphy E

更新日期：2016-08-29 00:00:00

abstract：:In this paper, we present an alternative approach to perform spike sorting of complex brain signals based on spiking neural networks (SNN). The proposed architecture is suitable for hardware implementation by using resistive random access memory (RRAM) technology for the implementation of synapses whose low latency (<...

journal_title：Frontiers in neuroscience

authors： Werner T,Vianello E,Bichler O,Garbin D,Cattaert D,Yvert B,De Salvo B,Perniola L

更新日期：2016-11-03 00:00:00

abstract：:This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC) cochlear model. The CAR part simulates the basilar membrane's (BM) response to sound. The FAC part models the outer hair cell (OHC), the inner hair cell (IHC), and the medial olivocochlear effere...

journal_title：Frontiers in neuroscience

authors： Xu Y,Thakur CS,Singh RK,Hamilton TJ,Wang RM,van Schaik A

更新日期：2018-04-10 00:00:00

abstract：:Our working model of the primate auditory cortex recognizes three major regions (core, belt, parabelt), subdivided into thirteen areas. The connections between areas are topographically ordered in a manner consistent with information flow along two major anatomical axes: core-belt-parabelt and caudal-rostral. Remarkab...

journal_title：Frontiers in neuroscience

authors： Hackett TA,de la Mothe LA,Camalier CR,Falchier A,Lakatos P,Kajikawa Y,Schroeder CE

更新日期：2014-04-22 00:00:00

abstract：:People are very precise in the discrimination of a line orientation relative to the cardinal (vertical and horizontal) axes, while their orientation discrimination sensitivity along the oblique axes is less refined. This difference in discrimination sensitivity along cardinal and oblique axes is called the "oblique ef...

journal_title：Frontiers in neuroscience

authors： Sysoeva OV,Davletshina MA,Orekhova EV,Galuta IA,Stroganova TA

更新日期：2016-01-21 00:00:00

abstract：:Tau protein is a microtubule-associated protein found in the axonal compartment that stabilizes neuronal microtubules under normal physiological conditions. Tau metabolism has attracted much attention because of its role in neurodegenerative disorders called tauopathies, mainly Alzheimer disease. Here, we review recen...

journal_title：Frontiers in neuroscience

authors： Fuster-Matanzo A,Llorens-Martín M,Jurado-Arjona J,Avila J,Hernández F

更新日期：2012-07-09 00:00:00

abstract：Background and Purpose:Oncological neurosurgery relies heavily on making continuous, intra-operative tumor-brain delineations based on image-guidance. Limitations of currently available imaging techniques call for the development of real-time image-guided resection tools, which allow for reliable functional and anatomi...

journal_title：Frontiers in neuroscience

authors： Soloukey S,Vincent AJPE,Satoer DD,Mastik F,Smits M,Dirven CMF,Strydis C,Bosch JG,van der Steen AFW,De Zeeuw CI,Koekkoek SKE,Kruizinga P

更新日期：2020-01-09 00:00:00

abstract：:Background: Stress-induced cellular changes in limbic brain structures contribute to the development of various psychopathologies. In vivo detection of these microstructural changes may help us to develop objective biomarkers for psychiatric disorders. Diffusion tensor imaging (DTI) is an advanced neuroimaging techniq...

journal_title：Frontiers in neuroscience

authors： Nagy SA,Vranesics A,Varga Z,Csabai D,Bruszt N,Bali ZK,Perlaki G,Hernádi I,Berente Z,Miseta A,Dóczi T,Czéh B

更新日期：2020-06-03 00:00:00

abstract：:The value of an object acquired by a particular action often determines the motivation to produce that action. Previous studies found neural signals related to the values of different objects or goods in the orbitofrontal cortex, while the values of outcomes expected from different actions are broadly represented in m...

journal_title：Frontiers in neuroscience

authors： Kim S,Cai X,Hwang J,Lee D

更新日期：2012-07-17 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs), also known as NG2 glia, arise from neural progenitor cells in the embryonic ganglionic eminences that also generate inhibitory neurons. They are ubiquitously distributed in the central nervous system, remain proliferative through life, and generate oligodendrocytes in both gray ...

journal_title：Frontiers in neuroscience

authors： Boshans LL,Factor DC,Singh V,Liu J,Zhao C,Mandoiu I,Lu QR,Casaccia P,Tesar PJ,Nishiyama A

更新日期：2019-08-08 00:00:00

abstract：Purpose:To improve the metoprolol therapeutic effectiveness, we aimed to explore whether baseline heart rate variability (HRV) indicators before metoprolol treatment were useful for predicting its efficacy for postural tachycardia syndrome (POTS). Methods:We recruited 45 children with POTS who received metoprolol and ...

journal_title：Frontiers in neuroscience

authors： Wang Y,Zhang C,Chen S,Liu P,Wang Y,Tang C,Jin H,Du J

更新日期：2019-11-12 00:00:00

abstract：:People with diabetes are more likely to experience sleep disturbance than those without. Sleep disturbance can cause daytime sleepiness in diabetic patients, which may impair their daytime performance or even lead to workplace injuries. Therefore, restoring the normal sleep-wake cycle is critical for diabetic patients...

journal_title：Frontiers in neuroscience

authors： Hou T,Wang C,Joshi S,O'Hara BF,Gong MC,Guo Z

更新日期：2019-09-20 00:00:00

abstract：:The trigeminovascular system (TS) activation and the vasoactive release from trigeminal endings, in proximity of the meningeal vessels, are considered two of the main effector mechanisms of migraine attacks. Several other structures and mediators are involved, however, both upstream and alongside the TS. Among these, ...

journal_title：Frontiers in neuroscience

authors： Greco R,Demartini C,Zanaboni AM,Piomelli D,Tassorelli C

更新日期：2018-03-19 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin shorter isoforms. Because of this, DMD patients may also experience d...

journal_title：Frontiers in neuroscience

authors： Persiconi I,Cosmi F,Guadagno NA,Lupo G,De Stefano ME

更新日期：2020-08-31 00:00:00

abstract：:Although the interplay between endogenous opioids and dopamine (DA) in the basal ganglia (BG) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. Vocal impairment is a common symptom of Parkinson's disease (PD), wherein DA depletion affects striosomes ri...

journal_title：Frontiers in neuroscience

authors： Kumar S,Mohapatra AN,Sharma HP,Singh UA,Kambi NA,Velpandian T,Rajan R,Iyengar S

更新日期：2019-07-03 00:00:00

abstract：:Stimulation of the pineal gland via its sympathetic innervation pathway results in the production of N-acetylserotonin and melatonin. Melatonin has many therapeutic roles and is heavily implicated in the regulation of the sleep-wake cycle. In addition, N-acetylserotonin has recently been reported to promote neurogenes...

journal_title：Frontiers in neuroscience

authors： Lumsden SC,Clarkson AN,Cakmak YO

更新日期：2020-04-02 00:00:00

abstract：:Aromatase cytochrome P450arom (cyp19) is the only enzyme that has the ability to convert androgens into estrogens. Estrogens, which are produced locally in the vertebrate brain play many fundamental roles in neuroendocrine functions, reproductive functions, socio-sexual behaviors, and neurogenesis. Radial glial cells ...

journal_title：Frontiers in neuroscience

authors： Xing L,Esau C,Trudeau VL

更新日期：2016-01-12 00:00:00

abstract：:Aversive memory is essential for survival, but in some situations its exacerbation can be potentially dangerous. There are several ways to modulate memory, among them, through stress-related hormones physiological release or administration of exogenous substances analogous to them. Recently, our group shown that a chr...

journal_title：Frontiers in neuroscience

authors： Gonçalves R,de Vargas LDS,Mello-Carpes PB

更新日期：2019-10-31 00:00:00

abstract：:The finding that the adult mammalian brain is still capable of producing neurons has ignited a new field of research aiming to identify the molecular mechanisms regulating adult neurogenesis. An improved understanding of these mechanisms could lead to the development of novel approaches to delay cognitive decline and ...

journal_title：Frontiers in neuroscience

authors： Stappert L,Klaus F,Brüstle O

更新日期：2018-11-05 00:00:00

abstract：Background:Emerging evidence demonstrates that diet-induced obesity disrupts corticolimbic circuits underlying emotional regulation. Studies directed at understanding how obesity alters brain and behavior are easily confounded by a myriad of complications related to obesity. This study investigated the early neurobiolo...

journal_title：Frontiers in neuroscience

authors： Vega-Torres JD,Azadian M,Rios-Orsini RA,Reyes-Rivera AL,Ontiveros-Angel P,Figueroa JD

更新日期：2020-06-30 00:00:00

abstract：:We generally experience a stable visual world in spite of regular disruptions caused by our own movements (saccades, blinks) or by the visual input itself (flashes, occlusions). In trying to understand the mechanisms responsible for this stability, saccades have been particularly well-studied, and a number of peri-sac...

journal_title：Frontiers in neuroscience

authors： Chota S,McLelland D,Lavergne L,Zimmermann E,Cavanagh P,VanRullen R

更新日期：2020-03-17 00:00:00

abstract：:In this paper, we introduce a novel automatic method for Corpus Callosum (CC) in midsagittal plane segmentation. The robust segmentation of CC in midsagittal plane is key role for quantitative study of structural features of CC associated with various neurological disorder such as epilepsy, autism, Alzheimer's disease...

journal_title：Frontiers in neuroscience

authors： Park G,Kwak K,Seo SW,Lee JM

更新日期：2018-09-11 00:00:00

abstract：:Adult neurogenesis is a tightly regulated process continuously taking place in the central nervous system of most mammalian species. In neuroscience research, transgenic animals bearing the tamoxifen-inducible CreERT2-Lox system are widely used. In this study, we made use of a Nestin-CreERT2/R26R-YFP transgenic mouse ...

journal_title：Frontiers in neuroscience

authors： Rotheneichner P,Romanelli P,Bieler L,Pagitsch S,Zaunmair P,Kreutzer C,König R,Marschallinger J,Aigner L,Couillard-Després S

更新日期：2017-02-01 00:00:00

abstract：:Brain-computer interfaces (BCIs), independent of the brain's normal output pathways, are attracting an increasing amount of attention as devices that extract neural information. As a typical type of BCI system, the steady-state visual evoked potential (SSVEP)-based BCIs possess a high signal-to-noise ratio and informa...

journal_title：Frontiers in neuroscience

authors： Zhao Y,Tang J,Cao Y,Jiao X,Xu M,Zhou P,Ming D,Qi H

更新日期：2018-02-15 00:00:00

abstract：:Enterochromaffin (EC) cells synthesize 95% of the body 5-HT and release 5-HT in response to mechanical or chemical stimulation. EC cell 5-HT has physiological effects on gut motility, secretion and visceral sensation. Abnormal regulation of 5-HT occurs in gastrointestinal disorders and Inflammatory Bowel Diseases (IBD...

journal_title：Frontiers in neuroscience

authors： Linan-Rico A,Ochoa-Cortes F,Beyder A,Soghomonyan S,Zuleta-Alarcon A,Coppola V,Christofi FL

更新日期：2016-12-19 00:00:00

abstract：:Purinergic signaling is critically involved in neuroinflammation associated with multiple sclerosis (MS) and its major inflammatory animal model, experimental autoimmune encephalomyelitis (EAE). Herein, we explored the expression of ectonucleoside triphosphate diphosphohydrolase1 (NTPDase1/CD39) in the spinal cord, at...

journal_title：Frontiers in neuroscience

authors： Jakovljevic M,Lavrnja I,Bozic I,Milosevic A,Bjelobaba I,Savic D,Sévigny J,Pekovic S,Nedeljkovic N,Laketa D

更新日期：2019-04-26 00:00:00

abstract：:ATP is released in an activity-dependent manner from different cell types in the brain, fulfilling different roles as a neurotransmitter, neuromodulator, in astrocyte-to-neuron communication, propagating astrocytic responses and formatting microglia responses. This involves the activation of different ATP P2 receptors...

journal_title：Frontiers in neuroscience

authors： Rodrigues RJ,Tomé AR,Cunha RA

更新日期：2015-04-28 00:00:00

abstract：:The enteric glia, a neural crest-derived cell type that composes the Enteric Nervous System, is involved in controlling gut functions, including motility, gut permeability, and neuronal communication. Moreover this glial cell could to give rise to new neurons. It is believed that enteric neurons are generated up to 21...

journal_title：Frontiers in neuroscience

authors： Veríssimo CP,Carvalho JDS,da Silva FJM,Campanati L,Moura-Neto V,Coelho-Aguiar JM

更新日期：2019-09-03 00:00:00