MicroRNAs Engage in Complex Circuits Regulating Adult Neurogenesis.

abstract：:To ensure survival, animals must update the internal representations of their environment in a trial-and-error fashion. Psychological studies of associative learning and neurophysiological analyses of dopaminergic neurons have suggested that this updating process involves the temporal-difference (TD) method in the bas...

journal_title：Frontiers in neuroscience

authors： Wen C,Ogura Y,Matsushima T

更新日期：2016-11-08 00:00:00

abstract：:Maternal overnutrition modulates body weight, development of metabolic failure and, potentially, neurodegenerative susceptibility in the offspring. Overnutrition sets a chronic pro-inflammatory profile that integrates peripheral and central immune activation nodes, damaging neuronal physiology and survival. Innate imm...

journal_title：Frontiers in neuroscience

authors： Cárdenas-Tueme M,Montalvo-Martínez L,Maldonado-Ruiz R,Camacho-Morales A,Reséndez-Pérez D

更新日期：2020-02-04 00:00:00

abstract：:Decades of research dedicated toward Alzheimer's disease (AD) has culminated in much of the current understanding of the neurodegeneration associated with disease. However, delineating the pathophysiology and finding a possible cure for the disease is still wanting. This is in part due to the lack of knowledge pertain...

journal_title：Frontiers in neuroscience

authors： Kumar A,Dhull DK,Mishra PS

更新日期：2015-06-09 00:00:00

abstract：:In this paper, we present an alternative approach to perform spike sorting of complex brain signals based on spiking neural networks (SNN). The proposed architecture is suitable for hardware implementation by using resistive random access memory (RRAM) technology for the implementation of synapses whose low latency (<...

journal_title：Frontiers in neuroscience

authors： Werner T,Vianello E,Bichler O,Garbin D,Cattaert D,Yvert B,De Salvo B,Perniola L

更新日期：2016-11-03 00:00:00

abstract：:Objectives: This prospective cohort study explored whether two distinguished sensory parameters predicted acupuncture effects in chronic pain patients; namely high temporal summation of pain (TS) indicating spinal synaptic facilitation as well as a low vibration detection threshold (VDT) indicating a loss of Aβ-fiber ...

journal_title：Frontiers in neuroscience

authors： Baeumler PI,Conzen P,Irnich D

更新日期：2019-07-11 00:00:00

abstract：:Many of the precise biological mechanisms of synaptic plasticity remain elusive, but simulations of neural networks have greatly enhanced our understanding of how specific global functions arise from the massively parallel computation of neurons and local Hebbian or spike-timing dependent plasticity rules. For simulat...

journal_title：Frontiers in neuroscience

authors： Galluppi F,Lagorce X,Stromatias E,Pfeiffer M,Plana LA,Furber SB,Benosman RB

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND:Some drugs of abuse down regulate the expression of cystine/glutamate (xCT) antiporter in the nucleus accumbens (Acb) after extinction or withdrawal. The altered level of xCT exchanger in Acb, a structure involved in ethanol reinforcement, may contribute to the pathological glutamatergic signaling, linked to...

journal_title：Frontiers in neuroscience

authors： Peana AT,Muggironi G,Bennardini F

更新日期：2014-10-06 00:00:00

abstract：:Tinnitus is unusual for such a common symptom in that there are few treatment options and those that are available are aimed at reducing the impact rather than specifically addressing the tinnitus percept. In particular, there is no drug recommended specifically for the management of tinnitus. Whilst some of the curre...

journal_title：Frontiers in neuroscience

authors： McFerran DJ,Stockdale D,Holme R,Large CH,Baguley DM

更新日期：2019-08-06 00:00:00

abstract：:The brain is the most complex organ in the body, controlling our highest functions, as well as regulating myriad processes which incorporate the entire physiological system. The effects of prospective therapeutic entities on the brain and central nervous system (CNS) may potentially cause significant injury, hence, CN...

journal_title：Frontiers in neuroscience

authors： Grainger AI,King MC,Nagel DA,Parri HR,Coleman MD,Hill EJ

更新日期：2018-08-31 00:00:00

abstract：:The aim of the present study was to test whether transcranial electrical stimulation can modulate illusory perception in the auditory domain. In two separate experiments we applied transcranial Direct Current Stimulation (anodal/cathodal tDCS, 2 mA; N = 60) and high-frequency transcranial Random Noise Stimulation (hf-...

journal_title：Frontiers in neuroscience

authors： Prete G,D'Anselmo A,Tommasi L,Brancucci A

更新日期：2017-06-20 00:00:00

abstract：:Over the past several decades, clinical studies have shown significant analgesic effects of acupuncture. The efficacy of acupuncture treatment has improved with the recent development of nanoporous needles (PN), which are produced by modifying the needle surface using nanotechnology. Herein, we showed that PN at acupo...

journal_title：Frontiers in neuroscience

authors： Bae SJ,Lim J,Lee S,Choi H,Jang JH,Kim YK,Oh JY,Park JH,Jung HS,Chae Y,In SI,Park HJ

更新日期：2019-06-20 00:00:00

abstract：:High angular resolution diffusion imaging (HARDI)-based tractography has been increasingly used in longitudinal studies on white matter macro- and micro-structural changes in the language network during language acquisition and in language impairments. However, test-retest reliability measurements are essential to asc...

journal_title：Frontiers in neuroscience

authors： Boukadi M,Marcotte K,Bedetti C,Houde JC,Desautels A,Deslauriers-Gauthier S,Chapleau M,Boré A,Descoteaux M,Brambati SM

更新日期：2019-01-14 00:00:00

abstract：:Schizophrenia is a severe neuropsychiatric disorder with persistence of symptoms throughout adult life in most of the affected patients. This unfavorable course is associated with multiple episodes and residual symptoms, mainly negative symptoms and cognitive deficits. The neural diathesis-stress model proposes that p...

journal_title：Frontiers in neuroscience

authors： Popovic D,Schmitt A,Kaurani L,Senner F,Papiol S,Malchow B,Fischer A,Schulze TG,Koutsouleris N,Falkai P

更新日期：2019-03-21 00:00:00

abstract：:The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutter. However, the whole-brain neural connectivity to LPT GABAergic neu...

journal_title：Frontiers in neuroscience

authors： Chen ZK,Yuan XS,Dong H,Wu YF,Chen GH,He M,Qu WM,Huang ZL

更新日期：2019-04-24 00:00:00

abstract：:On a large sample of 2288 Han Chinese undergraduates, we investigated how religion and DRD4 are related to human altruistic giving behavior as measured with the Andreoni-Miller Dictator Game. This game enables us to clearly specify (non-)selfishness, efficiency, and fairness motives for sharing. Participants were furt...

journal_title：Frontiers in neuroscience

authors： Jiang Y,Bachner-Melman R,Chew SH,Ebstein RP

更新日期：2015-09-24 00:00:00

abstract：:The massively parallel nature of biological information processing plays an important role due to its superiority in comparison to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits contemporary computer architectures. Physical-model neuromorphic...

journal_title：Frontiers in neuroscience

authors： Kungl AF,Schmitt S,Klähn J,Müller P,Baumbach A,Dold D,Kugele A,Müller E,Koke C,Kleider M,Mauch C,Breitwieser O,Leng L,Gürtler N,Güttler M,Husmann D,Husmann K,Hartel A,Karasenko V,Grübl A,Schemmel J,Meier K,Pet

更新日期：2019-11-14 00:00:00

abstract：:Platelet-rich plasma (PRP) is prepared by centrifuging fresh blood in an anticoagulant state, and harvesting the platelet-rich portion or condensing platelets. Studies have consistently demonstrated that PRP concentrates are an abundant source of growth factors, such as platelet-derived growth factor (PDGF), transform...

journal_title：Frontiers in neuroscience

authors： Chen NF,Sung CS,Wen ZH,Chen CH,Feng CW,Hung HC,Yang SN,Tsui KH,Chen WF

更新日期：2018-04-23 00:00:00

abstract：:Recent studies suggest cone degeneration in retinitis pigmentosa (RP) may result from intracellular energy depletion. We tested the hypothesis that cones die when depleted of energy by examining the effect of two bioenergetic, nutraceutical agents on cone survival. The study had three specific aims: firstly, we, studi...

journal_title：Frontiers in neuroscience

authors： Narayan DS,Chidlow G,Wood JPM,Casson RJ

更新日期：2019-11-15 00:00:00

abstract：:Transsynaptic connections enabling cell-cell adhesion and cellular communication are a vital part of synapse formation, maintenance and function. A recently discovered interaction between the Adhesion GPCRs Latrophilins and the type II single transmembrane proteins Teneurins at mammalian synapses is vital for synapse ...

journal_title：Frontiers in neuroscience

authors： Schöneberg T,Prömel S

更新日期：2019-03-12 00:00:00

abstract：:The walking mechanism of a prosthetic leg user is a tightly coordinated movement of several joints and limb segments. The interaction among the voluntary and mechanical joints and segments requires particular biomechanical insight. This study aims to analyze the inter-relationship between amputees' voluntary and mecha...

journal_title：Frontiers in neuroscience

authors： Jasni F,Hamzaid NA,Mohd Syah NE,Chung TY,Abu Osman NA

更新日期：2017-04-25 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease, the pathological features of which include the presence of Lewy bodies and the neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta. However, until recently, research on the pathogenesis and treatment of PD have progressed slowl...

journal_title：Frontiers in neuroscience

authors： Wang J,Wang F,Mai D,Qu S

更新日期：2020-11-26 00:00:00

abstract：:We used amyotrophic lateral sclerosis (ALS) as a model of prefrontal dysfunction in order to re-assess the potential neuronal substrates of two sub processes of working memory, namely information storage and filtering. To date it is unclear which exact neuronal networks sustain these two processes and the prefrontal c...

journal_title：Frontiers in neuroscience

authors： Vellage AK,Veit M,Kobeleva X,Petri S,Vielhaber S,Müller NG

更新日期：2016-04-19 00:00:00

abstract：:Although the interplay between endogenous opioids and dopamine (DA) in the basal ganglia (BG) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. Vocal impairment is a common symptom of Parkinson's disease (PD), wherein DA depletion affects striosomes ri...

journal_title：Frontiers in neuroscience

authors： Kumar S,Mohapatra AN,Sharma HP,Singh UA,Kambi NA,Velpandian T,Rajan R,Iyengar S

更新日期：2019-07-03 00:00:00

abstract：:In our complex acoustic environment, we are confronted with a mixture of sounds produced by several simultaneous sources. However, we rarely perceive these sounds as incomprehensible noise. Our brain uses perceptual organization processes to independently follow the emission of each sound source over time. If the acou...

journal_title：Frontiers in neuroscience

authors： Bidet-Caulet A,Bertrand O

更新日期：2009-09-15 00:00:00

abstract：:Neurodegenerative diseases are among the leading causes of disability and death worldwide. The disease-related socioeconomic burden is expected to increase with the steadily increasing life expectancy. In spite of decades of clinical and basic research, most strategies designed to manage degenerative brain diseases ar...

journal_title：Frontiers in neuroscience

authors： Castillo X,Castro-Obregón S,Gutiérrez-Becker B,Gutiérrez-Ospina G,Karalis N,Khalil AA,Lopez-Noguerola JS,Rodríguez LL,Martínez-Martínez E,Perez-Cruz C,Pérez-Velázquez J,Piña AL,Rubio K,García HPS,Syeda T,Vanoye-Carlo A,Vi

更新日期：2019-07-24 00:00:00

abstract：:Micro-Graphitic Single Crystal Diamond Multi Electrode Arrays (μG-SCD-MEAs) have so far been used as amperometric sensors to detect catecholamines from chromaffin cells and adrenal gland slices. Besides having time resolution and sensitivity that are comparable with carbon fiber electrodes, that represent the gold sta...

journal_title：Frontiers in neuroscience

authors： Tomagra G,Picollo F,Battiato A,Picconi B,De Marchis S,Pasquarelli A,Olivero P,Marcantoni A,Calabresi P,Carbone E,Carabelli V

更新日期：2019-04-09 00:00:00

abstract：:In this work, we present a neuromorphic architecture for head pose estimation and scene representation for the humanoid iCub robot. The spiking neuronal network is fully realized in Intel's neuromorphic research chip, Loihi, and precisely integrates the issued motor commands to estimate the iCub's head pose in a neuro...

journal_title：Frontiers in neuroscience

authors： Kreiser R,Renner A,Leite VRC,Serhan B,Bartolozzi C,Glover A,Sandamirskaya Y

更新日期：2020-06-23 00:00:00

abstract：:Oligodendrocyte precursor cells (OPCs), also known as NG2 glia, arise from neural progenitor cells in the embryonic ganglionic eminences that also generate inhibitory neurons. They are ubiquitously distributed in the central nervous system, remain proliferative through life, and generate oligodendrocytes in both gray ...

journal_title：Frontiers in neuroscience

authors： Boshans LL,Factor DC,Singh V,Liu J,Zhao C,Mandoiu I,Lu QR,Casaccia P,Tesar PJ,Nishiyama A

更新日期：2019-08-08 00:00:00

abstract：Objectives:Acute sleep deprivation (SD) seriously affects cognitive functions, such as attention, memory, and response inhibition. Previous neuroimaging studies have demonstrated a close relationship between the functional activities of the precuneus (PC) and the function of alert attention. However, the specific effec...

journal_title：Frontiers in neuroscience

authors： Li B,Zhang L,Zhang Y,Chen Y,Peng J,Shao Y,Zhang X

更新日期：2020-12-21 00:00:00

abstract：:Cognitive changes after menopause are a common complaint, especially as the loss of estradiol at menopause has been hypothesized to contribute to the higher rates of dementia in women. To explore the neural processes related to subjective cognitive complaints, this study examined resting state functional connectivity ...

journal_title：Frontiers in neuroscience

authors： Vega JN,Zurkovsky L,Albert K,Melo A,Boyd B,Dumas J,Woodward N,McDonald BC,Saykin AJ,Park JH,Naylor M,Newhouse PA

更新日期：2016-09-23 00:00:00