Change of cystine/glutamate antiporter expression in ethanol-dependent rats.

abstract：:Roughly one-third of the human lifetime is spent in sleep, yet the reason for sleep remains unclear. Understanding the physiologic function of sleep is crucial toward establishing optimal health. Several proposed concepts address different aspects of sleep physiology, including humoral and circuit-based theories of sl...

journal_title：Frontiers in neuroscience

authors： Lazarus M,Oishi Y,Bjorness TE,Greene RW

更新日期：2019-07-17 00:00:00

abstract：:Prior research has shown that musical beats are salient at the level of the cortex in humans. Yet below the cortex there is considerable sub-cortical processing that could influence beat perception. Some biases, such as a tempo preference and an audio frequency bias for beat timing, could result from sub-cortical proc...

journal_title：Frontiers in neuroscience

authors： Zuk NJ,Carney LH,Lalor EC

更新日期：2018-05-29 00:00:00

abstract：:Exposure in vivo (EXP) is a cognitive-behavioral treatment aimed at reducing pain-related fear in chronic pain, and has proven successful in reducing pain-related disability in patients with chronic low back pain (cLBP). The current longitudinal study aimed to reveal the neural correlates of changes in pain-related fe...

journal_title：Frontiers in neuroscience

authors： Timmers I,de Jong JR,Goossens M,Verbunt JA,Smeets RJ,Kaas AL

更新日期：2019-09-17 00:00:00

abstract：:While adult neurogenesis is considered to be restricted to the hippocampal dentate gyrus (DG) and the subventricular zone (SVZ), recent studies in humans and rodents provide evidence for newly generated neurons in regions generally considered as non-neurogenic, e.g., the striatum. Stimulating dopaminergic neurotransmi...

journal_title：Frontiers in neuroscience

authors： Salvi R,Steigleder T,Schlachetzki JC,Waldmann E,Schwab S,Winner B,Winkler J,Kohl Z

更新日期：2016-03-11 00:00:00

abstract：:Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the proteins involved in astrocyte network organization, potentiates donepe...

journal_title：Frontiers in neuroscience

authors： Vidal B,Droguerre M,Valdebenito M,Zimmer L,Hamon M,Mouthon F,Charvériat M

更新日期：2020-08-12 00:00:00

abstract：:SpiNNaker is a digital neuromorphic architecture, designed specifically for the low power simulation of large-scale spiking neural networks at speeds close to biological real-time. Unlike other neuromorphic systems, SpiNNaker allows users to develop their own neuron and synapse models as well as specify arbitrary conn...

journal_title：Frontiers in neuroscience

authors： Mikaitis M,Pineda García G,Knight JC,Furber SB

更新日期：2018-02-27 00:00:00

abstract：:Extrapancreatic nerves project to pancreatic islets directly or converge onto intrapancreatic ganglia. Intrapancreatic ganglia constitute a complex information-processing center that contains various neurotransmitters and forms an endogenous neural network. Both intrapancreatic ganglia and extrapancreatic nerves have ...

journal_title：Frontiers in neuroscience

authors： Li W,Yu G,Liu Y,Sha L

更新日期：2019-02-20 00:00:00

abstract：:The neuropeptide gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Vertebrates possess multiple GnRH forms that are classified into three main groups, namely GnRH1, GnRH2, and GnRH3. In order to gain more insights into the GnRH gene family in vertebrates, we sought...

journal_title：Frontiers in neuroscience

authors： Gaillard AL,Tay BH,Pérez Sirkin DI,Lafont AG,De Flori C,Vissio PG,Mazan S,Dufour S,Venkatesh B,Tostivint H

更新日期：2018-09-06 00:00:00

abstract：:Women with epilepsy commonly have premature onset of menopause. The decrease in estrogen levels is associated with increased occurrence of neurodegenerative processes and cognitive decline. Previously, we found that estradiol (E2) replacement in ovariectomized (OVX) female rats significantly reduced the seizure-relate...

journal_title：Frontiers in neuroscience

authors： Iacobas DA,Iacobas S,Nebieridze N,Velíšek L,Velíšková J

更新日期：2018-06-20 00:00:00

abstract：:[This corrects the article on p. 589 in vol. 10, PMID: 28066172.]. ...

journal_title：Frontiers in neuroscience

authors： Wang H,Li X,Shan L,Zhu J,Chen R,Li Y,Yuan W,Yang L,Huang J

更新日期：2017-02-13 00:00:00

abstract：:The acquisition of spatial cognition is essential for both everyday functioning (e.g., navigation) and more specific goals (e.g., mathematics), therefore being able to assess and monitor spatial cognition from the first years of life would be essential to predict developmental outcomes and timely intervene whenever sp...

journal_title：Frontiers in neuroscience

authors： Aprile G,Cappagli G,Morelli F,Gori M,Signorini S

更新日期：2020-09-16 00:00:00

abstract：:Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are reaching physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. T...

journal_title：Frontiers in neuroscience

authors： Hasler J,Marr B

更新日期：2013-09-10 00:00:00

abstract：:The massively parallel nature of biological information processing plays an important role due to its superiority in comparison to human-engineered computing devices. In particular, it may hold the key to overcoming the von Neumann bottleneck that limits contemporary computer architectures. Physical-model neuromorphic...

journal_title：Frontiers in neuroscience

authors： Kungl AF,Schmitt S,Klähn J,Müller P,Baumbach A,Dold D,Kugele A,Müller E,Koke C,Kleider M,Mauch C,Breitwieser O,Leng L,Gürtler N,Güttler M,Husmann D,Husmann K,Hartel A,Karasenko V,Grübl A,Schemmel J,Meier K,Pet

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:With the advent of the GeneChip Exon Arrays, it is now possible to extract "exon-level" expression estimates, allowing for detection of alternative splicing events, one of the primary mechanisms of transcript diversity. In the context of (1) a complex trait use case and (2) a human cerebellum vs. heart compa...

journal_title：Frontiers in neuroscience

authors： Laderas TG,Walter NA,Mooney M,Vartanian K,Darakjian P,Buck K,Harrington CA,Belknap J,Hitzemann R,McWeeney SK

更新日期：2011-05-13 00:00:00

abstract：:State-of-the-art large-scale neuromorphic systems require sophisticated spike event communication between units of the neural network. We present a high-speed communication infrastructure for a waferscale neuromorphic system, based on application-specific neuromorphic communication ICs in an field programmable gate ar...

journal_title：Frontiers in neuroscience

authors： Scholze S,Schiefer S,Partzsch J,Hartmann S,Mayr CG,Höppner S,Eisenreich H,Henker S,Vogginger B,Schüffny R

更新日期：2011-10-12 00:00:00

abstract：:Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder with a strong but complex genetic component. Recent family based exome-sequencing strategies have identified recurrent de novo mutations at specific genes, providing strong evidence for ASD risk, but also highlighting the extreme genetic heterogene...

journal_title：Frontiers in neuroscience

authors： Barnard RA,Pomaville MB,O'Roak BJ

更新日期：2015-12-17 00:00:00

abstract：:Manual scoring of polysomnography data is labor-intensive and time-consuming, and most existing software does not account for subjective differences and user variability. Therefore, we evaluated a supervised machine learning algorithm, SomnivoreTM, for automated wake-sleep stage classification. We designed an algorith...

journal_title：Frontiers in neuroscience

authors： Allocca G,Ma S,Martelli D,Cerri M,Del Vecchio F,Bastianini S,Zoccoli G,Amici R,Morairty SR,Aulsebrook AE,Blackburn S,Lesku JA,Rattenborg NC,Vyssotski AL,Wams E,Porcheret K,Wulff K,Foster R,Chan JKM,Nicholas CL,Fre

更新日期：2019-03-18 00:00:00

abstract：:Background: Degenerative cervical myelopathy (DCM), also known as cervical spondylotic myelopathy is the leading cause of spinal cord compression in adults. The mainstay of treatment is surgical decompression, which leads to partial recovery of symptoms, however, long term prognosis of the condition remains poor. Desp...

journal_title：Frontiers in neuroscience

authors： Akter F,Yu X,Qin X,Yao S,Nikrouz P,Syed YA,Kotter M

更新日期：2020-04-30 00:00:00

abstract：:Newborn neurons are continuously added to the hippocampal dentate gyrus throughout adulthood. In this review, we analyze the maturational stages that newborn granule neurons go through, with a focus on their unique morphological features during each stage under both physiological and pathological circumstances. In add...

journal_title：Frontiers in neuroscience

authors： Llorens-Martín M,Rábano A,Ávila J

更新日期：2016-01-19 00:00:00

abstract：:Adult neurogenesis is a tightly regulated process continuously taking place in the central nervous system of most mammalian species. In neuroscience research, transgenic animals bearing the tamoxifen-inducible CreERT2-Lox system are widely used. In this study, we made use of a Nestin-CreERT2/R26R-YFP transgenic mouse ...

journal_title：Frontiers in neuroscience

authors： Rotheneichner P,Romanelli P,Bieler L,Pagitsch S,Zaunmair P,Kreutzer C,König R,Marschallinger J,Aigner L,Couillard-Després S

更新日期：2017-02-01 00:00:00

abstract：:Diabetes mellitus (DM) and Parkinson's disease (PD) have been and will continue to be two common chronic diseases globally that are difficult to diagnose during the prodromal phase. Current molecular genetics, cell biological, and epidemiological evidences have shown the correlation between PD and DM. PD shares the sa...

journal_title：Frontiers in neuroscience

authors： Kong Y,Zhou H,Feng H,Zhuang J,Wen T,Zhang C,Sun B,Wang J,Guan Y

更新日期：2020-07-14 00:00:00

abstract：:Posterior parietal cortex is frequently activated during episodic memory retrieval but its role during retrieval and its interactions with the hippocampus are not yet clear. In this fMRI study, we investigated the neural bases of recognition memory when study repetitions and retrieval goals were manipulated. During en...

journal_title：Frontiers in neuroscience

authors： Ciaramelli E,Burianová H,Vallesi A,Cabeza R,Moscovitch M

更新日期：2020-11-03 00:00:00

abstract：:Currently the integrity of brain function that drives behavior is predominantly measured in terms of pure motor function, yet most human behavior is visually driven. A means of easily quantifying such visually-driven brain function for comparison against population norms is lacking. Analysis of eye-hand coordination (...

journal_title：Frontiers in neuroscience

authors： Junghans BM,Khuu SK

更新日期：2019-07-10 00:00:00

abstract：:Silymarin is a bioactive constituent isolated from milk thistle (Silybum marinum). Since its discovery, silymarin has been considered a gold standard drug in treating ailments related to the liver, resulting from alcohol consumption and viral hepatitis. This hepatoprotective nature of silymarin arises out of antioxida...

journal_title：Frontiers in neuroscience

authors： Rathore P,Arora I,Rastogi S,Akhtar M,Singh S,Samim M

更新日期：2020-10-26 00:00:00

abstract：:Spinocerebellar ataxia (SCA) is a part of the cerebellar neurodegenerative disease group that is diverse in genetics and phenotypes. It usually shows autosomal dominant inheritance. SCAs, always together with the cerebellar degeneration, may exhibit clinical deficits in brainstem or eye, especially retina or optic ner...

journal_title：Frontiers in neuroscience

authors： Park JY,Joo K,Woo SJ

更新日期：2020-08-21 00:00:00

abstract：:The digital neuromorphic hardware SpiNNaker has been developed with the aim of enabling large-scale neural network simulations in real time and with low power consumption. Real-time performance is achieved with 1 ms integration time steps, and thus applies to neural networks for which faster time scales of the dynamic...

journal_title：Frontiers in neuroscience

authors： van Albada SJ,Rowley AG,Senk J,Hopkins M,Schmidt M,Stokes AB,Lester DR,Diesmann M,Furber SB

更新日期：2018-05-23 00:00:00

abstract：:Event-related potential (ERP) studies using the task-switching paradigm show that multiple ERP components are modulated by activation of proactive control processes involved in preparing to repeat or switch task and reactive control processes involved in implementation of the current or new task. Our understanding of ...

journal_title：Frontiers in neuroscience

authors： Wong ASW,Cooper PS,Conley AC,McKewen M,Fulham WR,Michie PT,Karayanidis F

更新日期：2018-03-08 00:00:00

abstract：:Background: Tinnitus is a very common symptom that often causes distress and decreases the patient's quality of life. Apart from the well-known causes, tinnitus can in some cases be elicited by dysfunctions of the cervical spine or the temporomandibular joint (TMJ). To date however, it is unclear whether alleviation o...

journal_title：Frontiers in neuroscience

authors： Michiels S,Naessens S,Van de Heyning P,Braem M,Visscher CM,Gilles A,De Hertogh W

更新日期：2016-11-29 00:00:00

abstract：:Concerns regarding a drought in psychopharmacology have risen from many quarters. From one perspective, the wellspring of bedrock medications for anxiety disorders, depression, and schizophrenia was serendipitously discovered over 30 year ago, the swell of pharmaceutical investment in drug discovery has receded, and t...

journal_title：Frontiers in neuroscience

authors： Macdonald K,Feifel D

更新日期：2013-03-15 00:00:00

abstract：:Possible risks stemming from the employment of novel, micrometer-thin printed electrodes for direct current neural stimulation are discussed. To assess those risks, electrochemical methods are used, including cyclic voltammetry, square-wave voltammetry, and electrochemical impedance spectroscopy. Experiments were cond...

journal_title：Frontiers in neuroscience

authors： Pepłowski A,Rathi S,Piotrkowski B,Ziółkowski R,Janczak D,Krzemiński J,Brosch M,Jakubowska M

更新日期：2020-10-29 00:00:00