Direct Regulation of Aromatase B Expression by 17β-Estradiol and Dopamine D1 Receptor Agonist in Adult Radial Glial Cells.

abstract：:Identifying the multiple contributors to the audiometric loss of a hearing impaired (HI) listener at a particular frequency is becoming gradually more useful as new treatments are developed. Here, we infer the contribution of inner (IHC) and outer hair cell (OHC) dysfunction to the total audiometric loss in a sample o...

journal_title：Frontiers in neuroscience

authors： Johannesen PT,Pérez-González P,Lopez-Poveda EA

更新日期：2014-07-23 00:00:00

abstract：:Compelling data demonstrate that inflammation-associated anorexia directly results from the action of pro-inflammatory factors, primarily cytokines and prostaglandins E2, on the nervous system. For instance, the aforementioned pro-inflammatory factors can stimulate the activity of peripheral sensory neurons, and induc...

journal_title：Frontiers in neuroscience

authors： Gautron L,Layé S

更新日期：2010-01-08 00:00:00

abstract：:Sensory information can interact to impact perception and behavior. Foods are appreciated according to their appearance, smell, taste and texture. Athletes and dancers combine visual, auditory, and somatosensory information to coordinate their movements. Under laboratory settings, detection and discrimination are like...

journal_title：Frontiers in neuroscience

authors： Sperdin HF,Cappe C,Murray MM

更新日期：2010-05-15 00:00:00

abstract：:Introduction: The presence of a temporomandibular disorder is one of the most frequent causes of orofacial pain (OFP). When pain continues beyond tissue healing time, it becomes chronic and may be caused, among other factors, by the sensitization of higher-order neurons. The aim of this study is to describe psychologi...

journal_title：Frontiers in neuroscience

authors： Baroni A,Severini G,Straudi S,Buja S,Borsato S,Basaglia N

更新日期：2020-11-12 00:00:00

abstract：:The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal cord, providing sensory input to the micturition centers within the central nervous system. Under normal conditions, the continuous activation of these neurons during bladder distension goes mostly unnoticed. However, for ...

journal_title：Frontiers in neuroscience

authors： Grundy L,Caldwell A,Brierley SM

更新日期：2018-12-12 00:00:00

abstract：:The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo, we surveyed genes related to m...

journal_title：Frontiers in neuroscience

authors： Knowlton WM,Hubert T,Wu Z,Chisholm AD,Jin Y

更新日期：2017-05-10 00:00:00

abstract：:We performed this study to investigate the possibility of a definitive pattern of Galectin-3 (Gal-3) expression in the cerebrospinal fluid (CSF) and serum of Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS) patients. In our study, we collected the CSF and serum samples of 31 AD patients, 19 ALS patient...

journal_title：Frontiers in neuroscience

authors： Ashraf GM,Baeesa SS

更新日期：2018-06-29 00:00:00

abstract：Background:The peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of neurodegeneration, and cognition. Methods:145 participants underwent ...

journal_title：Frontiers in neuroscience

authors： Low A,Mak E,Stefaniak JD,Malpetti M,Nicastro N,Savulich G,Chouliaras L,Markus HS,Rowe JB,O'Brien JT

更新日期：2020-03-19 00:00:00

abstract：:Amyloid fibrils are physiologically insoluble biophysically specific β-sheet rich structures formed by the aggregation of misfolded proteins. In vivo tissue amyloid formation is responsible for more than 30 different disease states in humans and other mammals. One of these, Alzheimer's disease (AD), is the most common...

journal_title：Frontiers in neuroscience

authors： Buxbaum JN,Johansson J

更新日期：2017-03-15 00:00:00

abstract：:The structure of gene coexpression networks reflects the activation and interaction of multiple cellular systems. Since the pathology of neuropsychiatric disorders is influenced by diverse cellular systems and pathways, we investigated gene coexpression networks in major depression, and searched for putative unifying ...

journal_title：Frontiers in neuroscience

authors： Gaiteri C,Sibille E

更新日期：2011-08-30 00:00:00

abstract：:The oxytocin receptor (OXTR) has been observed in the periphery of neonatal C57BL/6J mice (Mus musculus), including facial regions and the anogenital area. In those studies, ligand specificity was confirmed with a congenital OXTR knockout mouse as well as competitive binding techniques. The aim of this study was to de...

journal_title：Frontiers in neuroscience

authors： Greenwood MA,Hammock EAD

更新日期：2019-05-24 00:00:00

abstract：:Aging is a complex natural phenomenon that is manifested by degenerative changes in the structure and function of cells and tissues. D-Galactose-induced aging mice are an artificial accelerated aging model that causes memory and learning impairment, oxidative stress, and neuroinflammation. In this study, we examined t...

journal_title：Frontiers in neuroscience

authors： Li H,Zheng L,Chen C,Liu X,Zhang W

更新日期：2019-09-18 00:00:00

abstract：:The mechanisms that control the frequency and propagation velocity of colonic migrating motor complexes (CMMCs) in mammals are poorly understood. Previous in vitro studies on whole mouse colon have shown that CMMCs occur frequently (~every 1-3 min) when the colon is devoid of all fecal content. Consequently, these stu...

journal_title：Frontiers in neuroscience

authors： Barnes KJ,Beckett EA,Brookes SJ,Sia TC,Spencer NJ

更新日期：2014-05-08 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal development and synaptic plasticity that is fundamental to neural circuit formation and cognition. It is also involved in the control of appetite and body weight, with mutations in the genes for BDNF and its receptor, TrkB, resulting in remarka...

journal_title：Frontiers in neuroscience

authors： Vanevski F,Xu B

更新日期：2013-03-21 00:00:00

abstract：:Vagal neurocircuits are vitally important in the co-ordination and modulation of GI reflexes and homeostatic functions. 5-hydroxytryptamine (5-HT; serotonin) is critically important in the regulation of several of these autonomic gastrointestinal (GI) functions including motility, secretion and visceral sensitivity. W...

journal_title：Frontiers in neuroscience

authors： Browning KN

更新日期：2015-10-29 00:00:00

abstract：:The cerebellum is one of the most consistent sites of abnormality in autism spectrum disorder (ASD) and cerebellar damage is associated with an increased risk of ASD symptoms, suggesting that cerebellar dysfunction may play a crucial role in the etiology of ASD. The cerebellum forms multiple closed-loop circuits with ...

journal_title：Frontiers in neuroscience

authors： D'Mello AM,Stoodley CJ

更新日期：2015-11-05 00:00:00

abstract：:Neurodegenerative diseases are among the leading causes of disability and death worldwide. The disease-related socioeconomic burden is expected to increase with the steadily increasing life expectancy. In spite of decades of clinical and basic research, most strategies designed to manage degenerative brain diseases ar...

journal_title：Frontiers in neuroscience

authors： Castillo X,Castro-Obregón S,Gutiérrez-Becker B,Gutiérrez-Ospina G,Karalis N,Khalil AA,Lopez-Noguerola JS,Rodríguez LL,Martínez-Martínez E,Perez-Cruz C,Pérez-Velázquez J,Piña AL,Rubio K,García HPS,Syeda T,Vanoye-Carlo A,Vi

更新日期：2019-07-24 00:00:00

abstract：BACKGROUND:Cortical modulation is likely to be involved in the various therapeutic effects of deep brain stimulation (DBS). However, it is currently difficult to predict the changes of cortical modulation during clinical adjustment of DBS. Therefore, we present a novel quantitative approach to estimate anatomical regio...

journal_title：Frontiers in neuroscience

authors： Hartmann CJ,Chaturvedi A,Lujan JL

更新日期：2015-02-10 00:00:00

abstract：:The mechanisms by which glucocorticoids regulate food intake and resulting body mass in humans are not well-understood. One potential mechanism could involve modulation of reward processing, but human stress models examining effects of glucocorticoids on behavior contain important confounds. Here, we studied individua...

journal_title：Frontiers in neuroscience

authors： Moeller SJ,Couto L,Cohen V,Lalazar Y,Makotkine I,Williams N,Yehuda R,Goldstein RZ,Geer EB

更新日期：2016-02-05 00:00:00

abstract：:Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual disability, resulting from the presence of an extra complete or segment of chromosome 21 (HSA21). In addition, trisomy of HSA21 contributes to altered energy metabolism that appears to be a strong determinant in the development of...

journal_title：Frontiers in neuroscience

authors： Dierssen M,Fructuoso M,Martínez de Lagrán M,Perluigi M,Barone E

更新日期：2020-07-08 00:00:00

abstract：:Abdominal obesity is important for understanding obesity, which is a worldwide medical problem. We explored structural and functional brain differences in people with abdominal and non-abdominal obesity by using multimodal neuroimaging and up-to-date analysis methods. A total of 274 overweight people, whose body mass ...

journal_title：Frontiers in neuroscience

authors： Park BY,Lee MJ,Kim M,Kim SH,Park H

更新日期：2018-10-11 00:00:00

abstract：:Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis. Members of the CRF family of neuropeptides, including urocortin 1 (UCN 1), UCN 2, and UCN 3, bind to the G protein-coupled...

journal_title：Frontiers in neuroscience

authors： Fox JH,Lowry CA

更新日期：2013-09-20 00:00:00

abstract：:After been exposed to the visual input, in the first year of life, the brain experiences subtle but massive changes apparently crucial for communicative/emotional and social human development. Its lack could be the explanation of the very high prevalence of autism in children with total congenital blindness. The prese...

journal_title：Frontiers in neuroscience

authors： Jure R

更新日期：2019-01-09 00:00:00

abstract：:Neurologic Music Therapy (NMT) is a novel impairment-focused behavioral intervention system whose techniques are based on the clinical neuroscience of music perception, cognition, and production. Auditory Stimulation (RAS) is one of the NMT techniques, which aims to develop and maintain a physiological rhythmic motor ...

journal_title：Frontiers in neuroscience

authors： Buard I,Dewispelaere WB,Thaut M,Kluger BM

更新日期：2019-02-19 00:00:00

abstract：:Diabetic neuropathy (DPN) is one of the most severe and yet most poorly understood complications of diabetes mellitus. In vivo imaging of dorsal root ganglia (DRG), a key structure for the understanding of DPN, has been restricted to animal studies. These have shown a correlation of decreased DRG volume with neuropath...

journal_title：Frontiers in neuroscience

authors： Jende JME,Kender Z,Rother C,Alvarez-Ramos L,Groener JB,Pham M,Morgenstern J,Oikonomou D,Hahn A,Juerchott A,Kollmer J,Heiland S,Kopf S,Nawroth PP,Bendszus M,Kurz FT

更新日期：2020-09-25 00:00:00

abstract：:Iron and calcium share the common feature of being essential for normal neuronal function. Iron is required for mitochondrial function, synaptic plasticity, and the development of cognitive functions whereas cellular calcium signals mediate neurotransmitter exocytosis, axonal growth and synaptic plasticity, and contro...

journal_title：Frontiers in neuroscience

authors： Núñez MT,Hidalgo C

更新日期：2019-02-12 00:00:00

abstract：:Up to now relatively little is known about interlimb reflexes (ILR). Especially it is not well known whether ILR may habituate or not to subsequent stimuli. The main aim of the present investigation was to explore the short term habituation behavior of ILR. The electromyogram was recorded over the tonically active bic...

journal_title：Frontiers in neuroscience

authors： Alaid S,Emmer A,Kornhuber ME

更新日期：2019-10-23 00:00:00

abstract：:This work presents sPyNNaker 4.0.0, the latest version of the software package for simulating PyNN-defined spiking neural networks (SNNs) on the SpiNNaker neuromorphic platform. Operations underpinning realtime SNN execution are presented, including an event-based operating system facilitating efficient time-driven ne...

journal_title：Frontiers in neuroscience

authors： Rhodes O,Bogdan PA,Brenninkmeijer C,Davidson S,Fellows D,Gait A,Lester DR,Mikaitis M,Plana LA,Rowley AGD,Stokes AB,Furber SB

更新日期：2018-11-20 00:00:00

abstract：:Studies of delay discounting typically have involved choices between smaller, immediate outcomes and larger, delayed outcomes. In a study of delay discounting in humans, Green et al. (2005) added a period of time prior to both outcomes, creating a delay common to both. They found that the subjective value of the more ...

journal_title：Frontiers in neuroscience

authors： Calvert AL,Green L,Myerson J

更新日期：2011-08-17 00:00:00

abstract：:Recent intriguing evidence suggests that metabolites of amyloid precursor protein (APP), mutated in familial forms of Alzheimer's disease (AD), play critical roles in developmental and postnatal neurogenesis. Of note is soluble APPα (sAPPα) that regulates neural progenitor cell proliferation. The APP family encompasse...

journal_title：Frontiers in neuroscience

authors： Lazarov O,Demars MP

更新日期：2012-06-04 00:00:00