Role of central vagal 5-HT3 receptors in gastrointestinal physiology and pathophysiology.

abstract：:The diagnosis of multiple sclerosis (MS) is usually based on clinical symptoms and signs of damage to the central nervous system, which is assessed using magnetic resonance imaging. The correct interpretation of these data requires excellent clinical expertise and experience. Deep neural networks aim to assist clinici...

journal_title：Frontiers in neuroscience

authors： Lopatina A,Ropele S,Sibgatulin R,Reichenbach JR,Güllmar D

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND AND AIMS:Malfunctions of enteric neurons are believed to play an important role in the pathophysiology of irritable bowel syndrome (IBS). Our aim was to investigate whether neuronal activity in biopsies from IBS patients is altered in comparison to healthy controls (HC). METHODS:Activity of human submucous ...

journal_title：Frontiers in neuroscience

authors： Ostertag D,Buhner S,Michel K,Pehl C,Kurjak M,Götzberger M,Schulte-Frohlinde E,Frieling T,Enck P,Phillip J,Schemann M

更新日期：2015-12-16 00:00:00

abstract：:Acupuncture is a traditional Chinese medicine treatment that has widely been used to modulate gastrointestinal dysfunction caused by irritable bowel syndrome (IBS) and to alleviate the resulting pain. Recent studies have shown that gastrointestinal dysfunction caused by IBS is associated with dysregulation of the brai...

journal_title：Frontiers in neuroscience

authors： Ma K,Liu Y,Shao W,Sun J,Li J,Fang X,Li J,Wang Z,Zhang D

更新日期：2020-12-15 00:00:00

abstract：:Recent studies suggest cone degeneration in retinitis pigmentosa (RP) may result from intracellular energy depletion. We tested the hypothesis that cones die when depleted of energy by examining the effect of two bioenergetic, nutraceutical agents on cone survival. The study had three specific aims: firstly, we, studi...

journal_title：Frontiers in neuroscience

authors： Narayan DS,Chidlow G,Wood JPM,Casson RJ

更新日期：2019-11-15 00:00:00

abstract：:Many of the precise biological mechanisms of synaptic plasticity remain elusive, but simulations of neural networks have greatly enhanced our understanding of how specific global functions arise from the massively parallel computation of neurons and local Hebbian or spike-timing dependent plasticity rules. For simulat...

journal_title：Frontiers in neuroscience

authors： Galluppi F,Lagorce X,Stromatias E,Pfeiffer M,Plana LA,Furber SB,Benosman RB

更新日期：2015-01-20 00:00:00

abstract：:Twenty years ago, the first report on the sound-induced double flash illusion, a visual illusion induced by sound, was published. In this paradigm, participants are presented with different numbers of auditory and visual stimuli. In case of an incongruent number of auditory and visual stimuli, the influence of auditor...

journal_title：Frontiers in neuroscience

authors： Keil J

更新日期：2020-04-03 00:00:00

abstract：:The right orbitofrontal cortex (rOFC) has been proposed as the region where conscious olfactory perception arises; however, evidence supporting this hypothesis has all been collected from neuroimaging and lesion studies in which only correlation and not a temporal pattern can be established. Continuous theta burst sti...

journal_title：Frontiers in neuroscience

authors： Villafuerte G,Miguel-Puga A,Arias-Carrión O

更新日期：2019-06-05 00:00:00

abstract：:Oxylipins are a series of bioactive lipid metabolites derived from polyunsaturated fatty acids that are involved in cerebral homeostasis and the development of intracerebral hemorrhage (ICH). However, comprehensive quantification of the oxylipin profile in ICH remains unknown. Therefore, an ICH mouse model was constru...

journal_title：Frontiers in neuroscience

authors： Yuan JJ,Chen Q,Xiong XY,Zhang Q,Xie Q,Huang JC,Yang GQ,Gong CX,Qiu ZM,Sang HF,Zi WJ,He Q,Xu R,Yang QW

更新日期：2020-09-23 00:00:00

abstract：:It has long been debated whether visual processing is, at least partially, a discrete process. Although vision appears to be a continuous stream of sensory information, sophisticated experiments reveal periodic modulations of perception and behavior. Previous work has demonstrated that the phase of endogenous neural o...

journal_title：Frontiers in neuroscience

authors： Chota S,VanRullen R

更新日期：2019-03-15 00:00:00

abstract：:The heart may be a mirror of the soul, but the human mind is more than its heart rate variability (HRV). Many techniques to quantify HRV promise to give a view of what is going on in the body or even the psyche of the subject under study. This "Hypothesis" paper gives, on the one hand, a critical view on the field of ...

journal_title：Frontiers in neuroscience

authors： Karemaker JM

更新日期：2020-12-21 00:00:00

abstract：:Inherited retinal diseases encompass a highly heterogenous group of disorders caused by a wide range of genetic variants and with diverse clinical symptoms that converge in the common trait of retinal degeneration. Indeed, mutations in over 270 genes have been associated with some form of retinal degenerative phenotyp...

journal_title：Frontiers in neuroscience

authors： Gallego C,Gonçalves MAFV,Wijnholds J

更新日期：2020-08-20 00:00:00

abstract：:Selection of the time-window mainly affects the effectiveness of piecewise feature extraction procedures. We present an enhanced bag-of-patterns representation that allows capturing the higher-level structures of brain dynamics within a wide window range. So, we introduce augmented instance representations with extend...

journal_title：Frontiers in neuroscience

authors： Collazos-Huertas D,Caicedo-Acosta J,Castaño-Duque GA,Acosta-Medina CD

更新日期：2020-02-25 00:00:00

abstract：:Some studies identified hypo-connectivity, while others showed hyper-connectivity of the insula in the autism spectrum disorders (ASD). These contradictory findings leave open the question of whether and to what extent functional connectivity of the insula is altered and how functional connectivity of the insula is as...

journal_title：Frontiers in neuroscience

authors： Xu J,Wang H,Zhang L,Xu Z,Li T,Zhou Z,Zhou Z,Gan Y,Hu Q

更新日期：2018-04-11 00:00:00

abstract：:Tau is an essential protein that physiologically promotes the assembly and stabilization of microtubules, and participates in neuronal development, axonal transport, and neuronal polarity. However, in a number of neurodegenerative diseases, including Alzheimer's disease (AD), tau undergoes pathological modifications i...

journal_title：Frontiers in neuroscience

authors： Pérez MJ,Jara C,Quintanilla RA

更新日期：2018-07-05 00:00:00

abstract：Background:Since subjective cognitive decline (SCD) was standardized in 2014, many studies have investigated its features. However, the risk of SCD (plus) progressing to AD is much higher, and yet there have been few studies reporting the risk factors and neuropsychological assessment characteristics of SCD (plus). Ob...

journal_title：Frontiers in neuroscience

authors： Hao L,Xing Y,Li X,Mu B,Zhao W,Wang G,Wang T,Jia J,Han Y

更新日期：2019-08-14 00:00:00

abstract：Introduction:Our hands, with their exquisite sensors, work in concert with our sensing brain to extract sensory attributes of objects as we engage in daily activities. One in two people with stroke experience impaired body sensation, with negative impact on hand use and return to previous valued activities. Valid, quan...

journal_title：Frontiers in neuroscience

authors： Carey LM,Mak-Yuen YYK,Matyas TA

更新日期：2020-09-23 00:00:00

abstract：:Ongoing brain activity has been implicated in the modulation of cortical excitability. The combination of electroencephalography (EEG) and transcranial magnetic stimulation (TMS) in a real-time triggered setup is a novel method for testing hypotheses about the relationship between spontaneous neuronal oscillations, co...

journal_title：Frontiers in neuroscience

authors： Schaworonkow N,Caldana Gordon P,Belardinelli P,Ziemann U,Bergmann TO,Zrenner C

更新日期：2018-12-13 00:00:00

abstract：:The sleep duration of adolescents has continued to decline over the past 20 years. Sleep insufficiency is one of the most important risk factors for obesity, but the mechanisms underlying the association are unclear. Therefore, the hypothalamic-regulated mechanisms of appetite and the circadian clock gene expression w...

journal_title：Frontiers in neuroscience

authors： Sun Q,Liu Y,Wei W,Wu D,Lin R,Wen D,Jia L

更新日期：2020-09-08 00:00:00

abstract：:Self-control exertion on an initial task has been associated with impaired performance on subsequent physical tasks also requiring self-control; an effect suggested to be mediated by changes in perceptions of pain and motivation. However, the effects of spending longer on the initial self-control task are unknown. Thi...

journal_title：Frontiers in neuroscience

authors： Boat R,Hunte R,Welsh E,Dunn A,Treadwell E,Cooper SB

更新日期：2020-10-08 00:00:00

abstract：:New neurons are generated in the hippocampal dentate gyrus from early development through adulthood. Progenitor cells and immature granule cells in the subgranular zone are responsive to changes in their environment; and indeed, a large body of research indicates that neuronal interactions and the dentate gyrus milieu...

journal_title：Frontiers in neuroscience

authors： Ngwenya LB,Danzer SC

更新日期：2019-01-09 00:00:00

abstract：:Using BOLD functional magnetic resonance imaging (fMRI) techniques, we examined the relationships between activities in the neural systems elicited by the decision stage of the Iowa Gambling Task (IGT), and food choices of either vegetables or snacks high in fat and sugar. Twenty-three healthy normal weight adolescent...

journal_title：Frontiers in neuroscience

authors： He Q,Xiao L,Xue G,Wong S,Ames SL,Xie B,Bechara A

更新日期：2014-11-04 00:00:00

abstract：:The neurohormone oxytocin (OXT) has been found to mediate the regulation of complex socioemotional cognition in multiple ways both in humans and other animals. Recent studies have investigated the effects of OXT in different levels of analysis (from genetic to behavioral) chiefly targeting its impact on the social com...

journal_title：Frontiers in neuroscience

authors： Theofanopoulou C

更新日期：2016-06-14 00:00:00

abstract：:Circadian rhythms of behavior and physiology are generated by central and peripheral circadian oscillators entrained by periodic environmental or physiological stimuli. A master circadian pacemaker in the hypothalamic suprachiasmatic nucleus (SCN) is directly entrained by daily light-dark (LD) cycles, and coordinates ...

journal_title：Frontiers in neuroscience

authors： Patton DF,Mistlberger RE

更新日期：2013-10-14 00:00:00

abstract：:The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development, and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction, and other behaviors and it...

journal_title：Frontiers in neuroscience

authors： Beretta CA,Dross N,Guiterrez-Triana JA,Ryu S,Carl M

更新日期：2012-04-23 00:00:00

abstract：:A well-defined granular layer 4 is a defining cytoarchitectonic feature associated with sensory areas of mammalian cerebral cortex, and one with hodological significance: the local axons ascending from cells in thalamorecipient layer 4 and connecting to layer 2/3 pyramidal neurons form a major feedforward excitatory i...

journal_title：Frontiers in neuroscience

authors： Shepherd GM

更新日期：2009-12-15 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fnins.2019.00117.]. ...

journal_title：Frontiers in neuroscience

authors： Zuo XN,Biswal BB,Poldrack RA

更新日期：2019-04-16 00:00:00

abstract：:Dopamine system plays a pivotal role in specific kinds of substance use disorders (SUD, i. e., cocaine and methamphetamine use disorders). Many studies addressed whether dopamine-involved craving could be alleviated by non-invasive brain stimulation (NIBS) techniques. Nevertheless, the outcomes were highly inconsisten...

journal_title：Frontiers in neuroscience

authors： Ma T,Sun Y,Ku Y

更新日期：2019-10-18 00:00:00

abstract：:Sensorineural hearing loss (SNHL), sometimes accompanied with tinnitus, is associated with dysfunctions within and outside the classical auditory pathway. The salience network, which is anchored in bilateral anterior insula and dorsal anterior cingulate cortex, has been implicated in sensory integration. Partial audit...

journal_title：Frontiers in neuroscience

authors： Xu XM,Jiao Y,Tang TY,Lu CQ,Zhang J,Salvi R,Teng GJ

更新日期：2019-03-19 00:00:00

abstract：:The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutter. However, the whole-brain neural connectivity to LPT GABAergic neu...

journal_title：Frontiers in neuroscience

authors： Chen ZK,Yuan XS,Dong H,Wu YF,Chen GH,He M,Qu WM,Huang ZL

更新日期：2019-04-24 00:00:00

abstract：:The trigeminovascular system (TS) activation and the vasoactive release from trigeminal endings, in proximity of the meningeal vessels, are considered two of the main effector mechanisms of migraine attacks. Several other structures and mediators are involved, however, both upstream and alongside the TS. Among these, ...

journal_title：Frontiers in neuroscience

authors： Greco R,Demartini C,Zanaboni AM,Piomelli D,Tassorelli C

更新日期：2018-03-19 00:00:00