Abstract:
BACKGROUND:Public health responses to outbreaks of dengue, chikungunya, and Zika virus have been stymied by the inability to control the primary vector, Aedes aegypti mosquitos. Consequently, the need for novel approaches to Aedes vector control is urgent. Placement of three autocidal gravid ovitraps (AGO traps) in ~85% of homes in a community was previously shown to sustainably reduce the density of female Ae. aegypti by >80%. Following the introduction of chikungunya virus (CHIKV) to Puerto Rico, we conducted a seroprevalence survey to estimate the prevalence of CHIKV infection in communities with and without AGO traps and evaluate their effect on reducing CHIKV transmission. METHODS AND FINDINGS:Multivariate models that calculated adjusted prevalence ratios (aPR) showed that among 175 and 152 residents of communities with and without AGO traps, respectively, an estimated 26.1% and 43.8% had been infected with CHIKV (aPR = 0.50, 95% CI: 0.37-0.91). After stratification by time spent in their community, protection from CHIKV infection was strongest among residents who reported spending many or all weekly daytime hours in their community:10.3% seropositive in communities with AGO traps vs. 48.7% in communities without (PR = 0.21, 95% CI: 0.11-0.41). The age-adjusted rate of fever with arthralgia attributable to CHIKV infection was 58% (95% CI: 46-66%). The monthly number of CHIKV-infected mosquitos and symptomatic residents were diminished in communities with AGO traps compared to those without. CONCLUSIONS:These findings indicate that AGO traps are an effective tool that protects humans from infection with a virus transmitted by Ae. aegypti mosquitos. Future studies should evaluate their protective effectiveness in large, urban communities.
journal_name
PLoS Negl Trop Disjournal_title
PLoS neglected tropical diseasesauthors
Sharp TM,Lorenzi O,Torres-Velásquez B,Acevedo V,Pérez-Padilla J,Rivera A,Muñoz-Jordán J,Margolis HS,Waterman SH,Biggerstaff BJ,Paz-Bailey G,Barrera Rdoi
10.1371/journal.pntd.0007538subject
Has Abstractpub_date
2019-07-25 00:00:00pages
e0007538issue
7eissn
1935-2727issn
1935-2735pii
PNTD-D-19-00401journal_volume
13pub_type
杂志文章abstract::[This corrects the article DOI: 10.1371/journal.pntd.0005125.]. ...
journal_title:PLoS neglected tropical diseases
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journal_title:PLoS neglected tropical diseases
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