Endocannabinoids and energy metabolism.

abstract：:We herein describe a family with thyroid hormone resistance. Thyroid hormones and basal TSH were elevated. Pituitary tumor or abnormality in thyroid hormone binding proteins were ruled out by appropriate tests. Mother and sister of the propositus presented similar abnormal hormonal features but no hyperthyroidism. Ini...

journal_title：Journal of endocrinological investigation

authors： Aguilar Diosdado M,Escobar-Jimenez L,Fernandez Soto ML,Garcia Curiel A,Escobar-Jimenez F

更新日期：1991-09-01 00:00:00

abstract：:Among the several antigens involved in autoimmune thyroid diseases, the microsomal antigen has been recently identified as the human thyroid peroxidase (TPO). The availability of highly purified TPO and anti-TPO monoclonal antibody (mAb) allowed us to study in more details anti-TPO autoimmune antibodies (aAb) and thei...

journal_title：Journal of endocrinological investigation

authors： Czarnocka B,Ruf J,Ferrand M,Lissitzky S,Carayon P

更新日期：1986-04-01 00:00:00

abstract：:The present experiments were undertaken to study the effect of complete food removal on body weight, pituitary growth hormone (GH), plasma GH and glucose concentration in male and female Wistar rats. Plasma and pituitary GH levels were measured by means of a specific radioimmunoassay. Plasma glucose concentration decr...

journal_title：Journal of endocrinological investigation

authors： Gonzalez C,Jolin T

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Adipose tissue has been suggested to influence bone density and metabolism through the effect of some adipokines. However, whether adiponectin and visfatin may correlate with bone metabolism is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin and visfatin with bone...

journal_title：Journal of endocrinological investigation

authors： Iacobellis G,Iorio M,Napoli N,Cotesta D,Zinnamosca L,Marinelli C,Petramala L,Minisola S,D'Erasmo E,Letizia C

更新日期：2011-01-01 00:00:00

abstract：:Stroke is one of the main causes of death and disability in the adult population. Changes in pituitary hormone secretion may be observed during the acute phase of stroke, representing part of the adaptive response to injury. However, reduced pituitary hormone secretion, caused by pituitary and/or hypothalamus damage, ...

journal_title：Journal of endocrinological investigation

authors： Bondanelli M,Ambrosio MR,Zatelli MC,Basaglia N,Degli Uberti EC

更新日期：2008-09-01 00:00:00

abstract：:Data concerning the cardiovascular manifestations of primary hyperparathyroidism (PHPT) are inconsistent, which is due, in part, to the decrease in disease severity over the last several decades. In areas where patients tend to be more symptomatic, data support the presence of cardiovascular findings including myocard...

journal_title：Journal of endocrinological investigation

authors： Walker MD,Silverberg SJ

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:To report the long-term effectiveness and safety of the recombinant human growth hormone Omnitrope®, a somatropin biosimilar to Genotropin®, in Italian patients with growth hormone deficiency (GHD) enrolled in the PATRO Adults study. METHODS:The PATRO Adults study is an ongoing observational, longitudinal, non...

journal_title：Journal of endocrinological investigation

authors： Ferone D,Profka E,Gasco V,Ambrosio MR,Colao A,Di Somma C,Puxeddu E,Arnaldi G,Pagano C,Zecchi E,Pietropoli A,Beck-Peccoz P

更新日期：2017-06-01 00:00:00

abstract：:Somatomedin was measured by rat bioassay in samples obtained from renal artery and vein, in order to study the role of this organ in the production of somatomedin activity. The results showed a significant difference, with an increase of the activity in the venous samples. According to the data reported in the literat...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Grimaldi P,Cocco R,Garibotto G,Ferrini S,Giordano G

更新日期：1979-07-01 00:00:00

abstract：:A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and l...

journal_title：Journal of endocrinological investigation

authors： Scirpa P,Mango D,Montemurro A,Battaglia F,Cantafio L

更新日期：1984-08-01 00:00:00

abstract：:Resistance to thyroid hormone (RTH) is a rare disease characterized by non-suppressed TSH in spite of high free thyroid hormone levels. Up to date, in the literature, there are more than 600 RTH cases, but co-incidental hypophyseal adenoma was reported in only 1 case. In the literature, despite reported cases with thy...

journal_title：Journal of endocrinological investigation

authors： Berker D,Aydin Y,Tutuncu YA,Isik S,Delibasi T,Berker M,Guler S,Kamel N

更新日期：2009-03-01 00:00:00

abstract：:The underlying mechanism leading to carcinogenesis involves genomic instability, likely related to aneuploidy. While p53 as a "guardian of the genome" is an appealing candidate as an initiator of genomic instability, its mutations or deletions usually occur late in the course of tumor progression. P53 may, however, be...

journal_title：Journal of endocrinological investigation

authors： Farid NR

更新日期：2001-07-01 00:00:00

abstract：:This study examined the association of depression, anxiety, and stress with Type 2 diabetes (T2DM) in Bahrain, an island-country with a very high prevalence of T2DM. This was a cross-sectional study involving administering Depression Anxiety Stress Scales (DASS)-21 structured depression, anxiety, and stress scale to 1...

journal_title：Journal of endocrinological investigation

authors： Almawi W,Tamim H,Al-Sayed N,Arekat MR,Al-Khateeb GM,Baqer A,Tutanji H,Kamel C

更新日期：2008-11-01 00:00:00

abstract：:Several in vivo experimental and clinical studies suggest that the production of thymic hormones, such as thymulin (Zn-FTS), is modulated by thyroid hormones. It was not determined in these studies, however whether such modulation is exerted directly on the thymic epithelial cells which synthesize and secrete thymic h...

journal_title：Journal of endocrinological investigation

authors： Mocchegiani E,Amadio L,Fabris N

更新日期：1990-02-01 00:00:00

abstract：:During a multicentric pilot screening program for congenital hypothyroidism a comparison between the results obtained from Urbino, an area characterized by low iodine supply and endemic goiter, and Rome, a non-endemic area, has been made. The evaluation of neonatal urinary iodine excretion in the two areas showed sign...

journal_title：Journal of endocrinological investigation

authors： Carta Sorcini M,Diodato A,Fazzini C,Sabini G,Carta S,Grandolfo ME,Guidi M,Vasta M,Locatelli De Maestri J,Donati L

更新日期：1988-04-01 00:00:00

abstract：:EP1572 UMV1843 [Aib-DTrp-DgTrp-CHO]) is a new peptido-mimetic GH secretagogue (GHS) showing binding potency to the GHS-receptor in animal and human tissues similar to that of ghrelin and peptidyl GHS. EP1572 induces marked GH increase after s.c. administration in neonatal rats. Preliminary data in 2 normal young men s...

journal_title：Journal of endocrinological investigation

authors： Broglio F,Boutignon F,Benso A,Gottero C,Prodam F,Arvat E,Ghè C,Catapano F,Torsello A,Locatelli V,Muccioli G,Boeglin D,Guerlavais V,Fehrentz JA,Martinez J,Ghigo E,Deghenghi R

更新日期：2002-09-01 00:00:00

abstract：:A possible participation of central serotoninergic or noradrenergic neurons on nyctohemeral periodicity of plasma TSH concentration was studied in the rat. Control rats exhibited normal nyctohemeral fluctuations of plasma TSH characterized by high AM (09:30) and low PM (18:30) values (397 +/- 45 vs. 207 +/- 28 ng/ml, ...

journal_title：Journal of endocrinological investigation

authors： Fukuda H,Mori M,Ohshima K,Kobayashi I

更新日期：1980-07-01 00:00:00

abstract：:The activities of total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were measured in cancerous and non-cancerous adjacent tissues from 15 patients with follicular thyroid cancer containing single nodule. SOD and GSH-Px activities were found lower but malondialdehyde levels hi...

journal_title：Journal of endocrinological investigation

authors： Durak I,Bayram F,Kavutcu M,Canbolat O,Oztürk HS

更新日期：1996-05-01 00:00:00

abstract：:Forty-eight morbidly obese patients were placed on a very low calorie (800 kcal) formula diet (OPTIFAST) for a 10-week period with the goal of achieving 10% weight loss within this time. Weekly serum leptin measurements were performed to determine whether changes in this adipose protein would serve as a useful marker ...

journal_title：Journal of endocrinological investigation

authors： Xenachis C,Samojlik E,Raghuwanshi MP,Kirschner MA

更新日期：2001-12-01 00:00:00

abstract：:Recently, bromocriptine has been successfully introduced as medical therapy for the pituitary hypersecreting syndromes of hyperprolactinemia and acromegaly. Subsequently, an inhibitory effect on ACTH secretion was reported using bromocriptine in Cushing's disease. While most studies have focused on the acute response ...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Jackson IM

更新日期：1982-03-01 00:00:00

abstract：:Pheochromocytoma (PHEO) occasionally associates with pathological lesions of the adrenal cortex. In most of them, ectopic adrenocorticotropic hormone (ACTH) produced by PHEO resulted in bilateral adrenocortical hyperplasia. The coexistence of PHEO and pre-clinical Cushing's syndrome (PCS) of the same adrenal gland has...

journal_title：Journal of endocrinological investigation

authors： Erem C,Hacihasanoglu A,Ersöz HO,Reis AK,Calik A,Ukinç K,Koçak M

更新日期：2005-06-01 00:00:00

abstract：:The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of ea...

journal_title：Journal of endocrinological investigation

authors： Cannarella R,Condorelli RA,Mongioì LM,La Vignera S,Calogero AE

更新日期：2018-01-01 00:00:00

abstract：:Neurological disorders, such as seizures, are not infrequently associated with anti-leukemic therapy. It has been hypothesized that a disrupted peptidergic transmission between neurons could be the cellular basis of the neurological dysfunction. Since endogenous opioids have been recently found to alter neuronal funct...

journal_title：Journal of endocrinological investigation

authors： Iannetti P,Fabbri A,Meloni G,Moleti ML,Ulisse S,Mandelli F,Isidori A,Imperato C

更新日期：1989-10-01 00:00:00

abstract：:The present study reports the biochemical and immunohistochemical findings in the cytosol of a Hürthle cell carcinoma as compared with that of normal thyroid tissue. Sephadex G-200 chromatography of the extract derived from a Hürthle cell carcinoma and from normal thyroid tissue revealed three identical pools. Pool I ...

journal_title：Journal of endocrinological investigation

authors： De Keyser L,Layfield L,Van Herle A,Costin A,Lewin K

更新日期：1984-10-01 00:00:00

abstract：:The regulation of GH secretion involves the harmonious integration of factors acting at the hypothalamic and pituitary levels summating to produce the peripheral patterns of intermittent GH secretion observed in man and experimental animals under physiologic and experimental conditions. SRIH and GHRH act primarily at ...

journal_title：Journal of endocrinological investigation

authors： Root AW

更新日期：1989-01-01 00:00:00

abstract：:The effect of an oral dose of 200 or 400 mg sodium valproate (DPA) on ACTH and cortisol secretion was assessed in 11 patients with Cushing's disease (3 bilaterally adrenalectomized), 3 patients with Nelson's syndrome and 6 patients with Addison's disease. In none of the patients examined DPA induced changes in ACTH (a...

journal_title：Journal of endocrinological investigation

authors： Loli P,Berselli ME,Frascatani F,Muratori F,Tagliaferri M

更新日期：1984-04-01 00:00:00

abstract：:Anorexia nervosa (AN) is a complex mental disorder presenting psychiatric and physical symptoms. Literature recognizes the role of several factors in the pathogenesis of this disorder, according to the biopsychosocial model. Many mechanisms are still partly unclear. Endocrine and metabolic alterations usually occur in...

journal_title：Journal of endocrinological investigation

authors： Abbate Daga G,Gianotti L,Mondelli V,Quartesan R,Fassino S

更新日期：2004-11-01 00:00:00

abstract：:We investigated ACTH and cortisol responses after ovine CRF injection (1 microgram/kg one bolus) in a group of 11 drug-free patients suffering from major depression. When compared to sex- and age-matched normal controls, our depressed patients showed: Higher ACTH basal values (p less than 0.002); higher cortisol basal...

journal_title：Journal of endocrinological investigation

authors： Nerozzi D,Bersani G,Melia E,Magnani A,Antonozzi I,Frajese G

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:Thyroid hormone resistance (RTH β) is a rare genetic disorder characterized by an altered response of target tissue to the action of thyroid hormone. Few studies on RTH β have been carried out in southern European populations. We aimed to describe the clinical and genetic characteristics at the time of diagno...

journal_title：Journal of endocrinological investigation

authors： Vela A,Pérez-Nanclares G,Ríos I,Rica I,Portillo N,Castaño L,Spanish Group for the Study of RTH.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Immune dysfunction is very common in diabetes mellitus (DM). However, there is no evidence whether such immune dysfunction can influence the development of DM, especially the development of diabetic nephropathy (DN). AIM:To investigate the influence of absence of T cells on DN. MATERIALS AND METHODS:Balb/c...

journal_title：Journal of endocrinological investigation

authors： Lin S,Xu PC,Huang QE,Jia JY,Jia ZH,Wei L,Zheng ZF,Shang WY

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:In patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient de...

journal_title：Journal of endocrinological investigation

authors： Pellegrini M,Rahimi F,Boschetti S,Devecchi A,De Francesco A,Mancino MV,Toppino M,Morino M,Fanni G,Ponzo V,Marzola E,Abbate Daga G,Broglio F,Ghigo E,Bo S

更新日期：2020-10-07 00:00:00