Long term bromocriptine therapy in Cushing's disease.

abstract：:Our aim was to investigate the effect of GnRH-agonist (GnRH-a) induced suppression of plasma sex steroids on serum GH, insulin like growth factor-I (IGF-I) and insulin levels after an oral glucose load (OGTT) in women with polycystic ovary syndrome (PCOS). Serum insulin, GH and IGF-I levels during a 75-g 4-h OGTT were...

journal_title：Journal of endocrinological investigation

authors： Tropeano G,Liberale I,Vuolo IP,Barini A,Caroli G,Carfagna P,Menini E

更新日期：1997-04-01 00:00:00

abstract：:Prolactin (PRL) circulates as multiple molecular weight variants: glycosylated phosphorylated, deamidated and sulphated forms. The profiles of the forms, as determined by isoelectrofocusing (IEF), differ in physiological and pathological conditions. The case of a 72-year-old woman affected by an invasive prolactinoma ...

journal_title：Journal of endocrinological investigation

authors： Guido R,Valenti S,Foppiani L,De Martini D,Cossu M,Giusti M

更新日期：1997-05-01 00:00:00

abstract：:The long arm of the Y chromosome contains genes mapped in loci involved in male infertility, short stature and gonadoblastoma. However, many of these genes have not been fully characterized, and are not currently investigated in patients affected by such diseases. We report a study aimed to the genomic characterizatio...

journal_title：Journal of endocrinological investigation

authors： Stuppia L,Gatta V,Fogh I,Gaspari AR,Grande R,Morizio E,Fantasia D,Pizzuti A,Calabrese G,Palka G

更新日期：2000-11-01 00:00:00

abstract：:Because women affected by polycystic ovary syndrome (PCOS) present an increased cardiovascular risk, the safety of estroprogestin treatment is debated and contrasting data have been reported. However, cardiovascular risk is not the same in all PCOS women and individual cardiovascular risk should be assessed before sta...

journal_title：Journal of endocrinological investigation

authors： Carmina E

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The relative contribution of fasting and post-prandial glucose to glycated hemoglobin (HbA1c) is controversial. In the present study, we assessed the relationship with HbA1c of fasting and post-prandial glucose measured in a more naturalistic setting, through home glucose self-monitoring or with a continuous ...

journal_title：Journal of endocrinological investigation

authors： Monami M,Lamanna C,Lambertucci L,Longo R,Cocca C,Addante F,Lotti E,Masotti G,Marchionni N,Mannucci E

更新日期：2006-07-01 00:00:00

abstract：:A 45-year-old man presented with gynecomastia, hypertension and a large left adrenal mass. Further evaluation revealed elevated serum concentrations of estrogen, estrone sulfate, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, deoxycorticosterone, and aldosterone and increased 24-hour urinary ...

journal_title：Journal of endocrinological investigation

authors： Zayed A,Stock JL,Liepman MK,Wollin M,Longcope C

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:The diagnosis of polycystic ovary syndrome (PCOS) is based on a combination of various clinical phenotypes in each patient. However, insulin resistance (IR) and dysmetabolism are not included in the diagnostic criteria of PCOS. Therefore, the definition of PCOS is controversial. The objective of this study is t...

journal_title：Journal of endocrinological investigation

authors： Zhang L,Fang X,Li L,Liu R,Zhang C,Liu H,Tan M,Yang G

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To report the clinical implications of an initial experience with transoral endoscopic thyroidectomy vestibular approach (TOETVA). METHODS:From March to November 2017, five cases of TOETVA were performed. Data reported include patient demographics, indication for surgery, extent of surgery, operative time, the...

journal_title：Journal of endocrinological investigation

authors： Bakkar S,Al Hyari M,Naghawi M,Corsini C,Miccoli P

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

journal_title：Journal of endocrinological investigation

authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Levothyroxine (L-T4) treatment aims to minimize the risk of differentiated thyroid cancer (DTC) recurrence and should be tailored to patient risk stratification and potential morbidity from adverse effects. AIM:To evaluate the effectiveness of current recommendations on L-T4 treatment of DTC patients in cli...

journal_title：Journal of endocrinological investigation

authors： Martins de Almeida JF,Gonçalves Tsumura W,Vaisman M,Montalli Assumpção LV,Ward LS

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:Female Sexual Dysfunction (FSD) is a still poorly studied and underdiagnosed condition. The aim of the study was to produce an improved version of FSFI-6 (6-Item Version of the Female Sexual Function Index), entitled Female Sexual Dysfunction Index-6 (FSDI-6), and to estimate its accuracy as a screening instrum...

journal_title：Journal of endocrinological investigation

authors： Maseroli E,Fanni E,Fambrini M,Ragghianti B,Limoncin E,Mannucci E,Maggi M,Vignozzi L

更新日期：2016-04-01 00:00:00

abstract：:Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been analyzed for total pro...

journal_title：Journal of endocrinological investigation

authors： Federspil G,Vettor R,Bossi A,Sicolo N

更新日期：1979-04-01 00:00:00

abstract：:The present study was performed in 30 patients who needed steroid therapy: courses of triamcinolone or DTM 8-15 given orally lasted 30 days. In 15 of these patients glucoactive corticosteroids were administered in combination with 5 micrograms/day of 25OH-vitamin D3 (25OHD3). 47Calcium oral test and 99mTc-MDP kinetics...

journal_title：Journal of endocrinological investigation

authors： Nuti R,Vattimo A,Turchetti V,Righi G

更新日期：1984-10-01 00:00:00

abstract：:Pendred syndrome is an autosomal recessive disorder characterized by congenital sensorineural deafness, goiter, and impaired iodide organification. It is caused by mutations in the PDS gene. Most published mutation studies of Pendred syndrome have dealt with Western populations. In this study, we examined clinical and...

journal_title：Journal of endocrinological investigation

authors： Snabboon T,Plengpanich W,Saengpanich S,Sirisalipoch S,Keelawat S,Sunthornyothin S,Khovidhunkit W,Suwanwalaikorn S,Sridama V,Shotelersuk V

更新日期：2007-12-01 00:00:00

abstract：PURPOSE:Hypercortisolism has detrimental effects on bone metabolism with the consequences of bone loss and bone fractures. We aimed to evaluate the frequency of vertebral fragility fractures and to determine the factors associated with Cushing's syndrome (CS). METHODS:A total of 135 patients diagnosed with Cushing's s...

journal_title：Journal of endocrinological investigation

authors： Apaydın T,Yavuz DG

更新日期：2021-01-09 00:00:00

abstract：:The role of androgens in human sexuality as regards the mechanism of erection and the pathogenesis of impotence is under debate. In addition, it is difficult to define the psychosocial impact of both hypogonadism and androgen replacement. However, sexual hormones largely influence mood, well-being, and quality of life...

journal_title：Journal of endocrinological investigation

authors： Carosa E,Volpe R,Martini P,Brandetti F,Di Stasi SM,Lombardo F,Salacone P,Sgrò P,Gandini L,Lenzi A,Jannini EA

更新日期：2005-01-01 00:00:00

abstract：:The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of ea...

journal_title：Journal of endocrinological investigation

authors： Cannarella R,Condorelli RA,Mongioì LM,La Vignera S,Calogero AE

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Apart from waist circumference, other adiposity measures, such as subscapular skin fold (SST), arouse growing interest due to their relationship to metabolic complications and cardiovascular risk. The IGF-I system is deregulated in obese subjects in proportion to their degree of visceral adiposity. AIM:To e...

journal_title：Journal of endocrinological investigation

authors： Savastano S,Barbato A,Di Somma C,Guida B,Pizza G,Barrea L,Avallone S,Schiano di Cola M,Strazzullo P,Colao A

更新日期：2012-11-01 00:00:00

abstract：:The aim of our study was to investigate the effects of estradiol (E2) and/or progesterone (P4) bilateral ovariectomized rats on gene expressions of adenylyl cyclases (AC2, AC4, AC6, AC9). Non-pregnant (NP) Wister rats (between post-natal 10 and 12 weeks) and normal pregnant rats (between postnatal 10 and 14 weeks) wer...

journal_title：Journal of endocrinological investigation

authors： Asano K,Okawa T,Matsuoka I,Suzuki Y,Sato A

更新日期：2005-04-01 00:00:00

abstract：AIM:The optimal GH regimen, in terms of cost-effectiveness, in children with normal GH immunoreactivity but reduced bioactivity is still debated. METHODS:In 12 GH-deficient (GHD) and 12 bioinactive GH children undergoing GH treatment we evaluated the increase in growth velocity, the difference between target height an...

journal_title：Journal of endocrinological investigation

authors： Pagani S,Meazza C,Laarej K,Cantoni F,Bozzola M

更新日期：2011-05-01 00:00:00

abstract：:EP1572 UMV1843 [Aib-DTrp-DgTrp-CHO]) is a new peptido-mimetic GH secretagogue (GHS) showing binding potency to the GHS-receptor in animal and human tissues similar to that of ghrelin and peptidyl GHS. EP1572 induces marked GH increase after s.c. administration in neonatal rats. Preliminary data in 2 normal young men s...

journal_title：Journal of endocrinological investigation

authors： Broglio F,Boutignon F,Benso A,Gottero C,Prodam F,Arvat E,Ghè C,Catapano F,Torsello A,Locatelli V,Muccioli G,Boeglin D,Guerlavais V,Fehrentz JA,Martinez J,Ghigo E,Deghenghi R

更新日期：2002-09-01 00:00:00

abstract：:Non-classical congenital adrenal hyperplasia (NCAH) is a morbid condition sustained by the reduced function of one of the enzymes involved in the adrenal steroid biosynthesis pathway, mainly the 21-hydroxylase. Different degrees of enzyme activity impairment determine different clinical pictures, with childhood or pos...

journal_title：Journal of endocrinological investigation

authors： Einaudi S,Napolitano E,Restivo F,Motta G,Baldi M,Tuli G,Grosso E,Migone N,Menegatti E,Manieri C

更新日期：2011-10-01 00:00:00

abstract：:A technique has been developed with which it has been possible to quantify the output of a wide variety of agonists including catecholamines, glucocorticoids, mineralocorticoids, enkephalins and various peptides, from the adrenal gland in the conscious unrestrained calf; also to investigate responses to electrical sti...

journal_title：Journal of endocrinological investigation

authors： Edwards AV,Ghatei MA,Bloom SR

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Subtotal parathyroidectomy (SP) and total parathyroidectomy (TP) with autotransplantation (TPai) are the most commonly adopted operations for the treatment of secondary hyperparathyroidism (2HPT). TP without autotransplantation had previously been confined to patients with advanced dialytic vintage, not elig...

journal_title：Journal of endocrinological investigation

authors： Conzo G,Perna AF,Sinisi AA,Palazzo A,Stanzione F,Della Pietra C,Livrea A

更新日期：2012-01-01 00:00:00

abstract：:Glucocorticoid receptors (GR) and 3-O-methyl-D glucose (3-O-MG) transport were determined in mononuclear leukocytes (MNL) from 11 abdominal obese subjects, 10 pituitary-dependent Cushing's syndrome (Cushing's disease) and 10 healthy controls. Using a whole-cell competitive binding assay and 3H-dexamethasone as tracer,...

journal_title：Journal of endocrinological investigation

authors： Güven M,Hatemi H,Taşan E,Altuntaş Y,Ulutin T,Tezcan V,Kanigür-Sultuybek G

更新日期：1998-11-01 00:00:00

abstract：:Although the role of biogenic amines in the regulation of gonadotropin release has been studied extensively, the precise role of dopamine (DA) in stimulating LHRH and/or LH release is still controversial. In the present study 6 eugonadal women, aged 20-30, were given an LHRH infusion on day 6 of the menstrual cycle an...

journal_title：Journal of endocrinological investigation

authors： Pucci E,Franchi F,Kicovic PM,Sgrilli R,Barletta D,Argenio GF,Gasperi M,Bernini GP,Luisi M

更新日期：1981-01-01 00:00:00

abstract：CONTEXT:The antiproliferative mechanism of mycophenolate acid (MPA) suggests a beneficial effect in patients with Graves' orbitopathy (GO). OBJECTIVE:To systematically analyze for the first time adverse events (AEs) during MPA treatment in GO. DESIGN:Prospective longitudinal study. SETTING:Academic tertiary referral...

journal_title：Journal of endocrinological investigation

authors： Riedl M,Kuhn A,Krämer I,Kolbe E,Kahaly GJ

更新日期：2016-06-01 00:00:00

abstract：:Graves' disease (GD) is the most prevalent cause of thyrotoxicosis in children. Because spontaneous and lasting resolution of this condition occurs in only a minority of patients, most pediatric patients with GD will need radioactive iodine treatment (131I) or thyroidectomy. Whereas the medication propylthiouracil (PT...

journal_title：Journal of endocrinological investigation

authors： Rivkees SA

更新日期：2016-11-01 00:00:00

abstract：:Many hirsute women may present a form of functional ovarian hyperandrogenism (FOH), since they show an exaggerated 17-hydroxyprogesterone (17-OHP) response to GnRH agonists administration. As the failure of dexamethasone to reduce testosterone levels may be indicative of an ovarian source of androgen secretion, we eva...

journal_title：Journal of endocrinological investigation

authors： Re T,Barbetta L,Dall'Asta C,Faglia G,Ambrosi B

更新日期：2002-01-01 00:00:00

abstract：:Orbital fibroblasts exhibit a unique phenotype including exaggerated responses to proinflammatory cytokines. We hypothesize that the unusual susceptability of these fibroblasts to molecular cues underlies the involvement of the orbit in Graves' ophthalmopathy. A number of attributes of orbital fibroblasts are reviewed...

journal_title：Journal of endocrinological investigation

authors： Smith TJ

更新日期：2004-03-01 00:00:00