Hypoproteinemia in acromegaly.

abstract：CONTEXT:The latest guidelines of the 4th International Workshop on Asymptomatic Primary Hyperparathyroidism (aPHPT) reintroduced hypercalciuria (i.e. urinary calcium > 400 mg/day) as criterion for surgery. However, the value of hypercalciuria as a predictor of nephrolithiasis and the correct cut-off values still need t...

journal_title：Journal of endocrinological investigation

authors： Saponaro F,Cetani F,Mazoni L,Apicella M,Di Giulio M,Carlucci F,Scalese M,Pardi E,Borsari S,Bilezikian JP,Marcocci C

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:We examined auxological changes in growth hormone (GH)-treated children in Italy using data from the Italian cohort of the multinational observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS) of pediatric patients requiring GH treatment. METHODS:We studied 711 children (me...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Iughetti L,Loche S,Maghnie M,Vottero A,GeNeSIS National Board on behalf of the GeNeSIS Italian Investigators.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The significance of vitamin D deficiency in the incidence of bone fractures in children has been under investigated. Here, we aimed to associate serum 25-hydroxyvitamin D levels and fractures in Saudi children. MATERIALS AND METHODS:This cross-sectional study was conducted in 1022 Saudi children without fra...

journal_title：Journal of endocrinological investigation

authors： Al-Daghri NM,Aljohani N,Rahman S,Sabico S,Al-Attas OS,Alokail MS,Al-Ajlan A,Chrousos GP

更新日期：2016-10-01 00:00:00

abstract：:We report the case of a patient who developed Graves' disease and a papillary thyroid cancer only 5 years after irradiation and adjuvant chemotherapy for Hodgkin's disease. This case is peculiar for the very short latency time between Hodgkin's disease treatment and thyroid cancer development, an event possibly relate...

journal_title：Journal of endocrinological investigation

authors： Belfiore A,Pellegriti G,Milone G,Vigneri G,Gangemi P,Fiumara A,Vigneri R

更新日期：1995-12-01 00:00:00

abstract：:Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...

journal_title：Journal of endocrinological investigation

authors： Liu D,Zhu Y,Yang C,Long J,Yao C,Li J,Wang S

更新日期：2012-05-01 00:00:00

abstract：:We have developed a sandwich-type enzyme immunoassay for human chorionic gonadotropin (hCG), in which antibody Fab'-beta-D-galactosidase complex and an antibody-immobilized silicone rubber solid phase were used. Despite the fact this assay system crossreacted about 40% with human luteinizing hormone (LH) that contains...

journal_title：Journal of endocrinological investigation

authors： Sekiya T,Furuhashi Y,Goto S,Kaseki S,Tomoda Y,Kato K

更新日期：1981-07-01 00:00:00

abstract：:Because women affected by polycystic ovary syndrome (PCOS) present an increased cardiovascular risk, the safety of estroprogestin treatment is debated and contrasting data have been reported. However, cardiovascular risk is not the same in all PCOS women and individual cardiovascular risk should be assessed before sta...

journal_title：Journal of endocrinological investigation

authors： Carmina E

更新日期：2013-05-01 00:00:00

abstract：:Human gonadotropins are widely used for induction of ovulation in the treatment of anovulatory infertility and for induction of multiple follicular development (MFD) in in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), and artificial insemination with husband's semen (AIH) programs. Reported is a pa...

journal_title：Journal of endocrinological investigation

authors： Mais V,Melis GB,Antinori D,Paoletti AM,Strigini F,Guerriero S,de Ruggiero A,Fioretti P

更新日期：1990-10-01 00:00:00

abstract：:The effects of graded infusions of atrial natriuretic peptide (ANP) on hemodynamics, renal function, plasma renin activity (PRA) and plasma arginine vasopressin (AVP) were investigated in a two part study in 6 volunteers. Three 30-min iv infusions of either saline control or ANP at graded rates of 4, 10 and 40 pmol kg...

journal_title：Journal of endocrinological investigation

authors： Williams TD,Walsh KP,Pitts E,Sutton R,Lightman SL

更新日期：1988-01-01 00:00:00

abstract：:Gonadotropins control male and female gonadal function by acting through specific receptors. The recent description of several mutations in LH and FSH receptors has significantly improved our understanding of the pathophysiology of several sexual disorder. Both gain- and loss-of-function germline mutations leading to ...

journal_title：Journal of endocrinological investigation

authors： Beck-Peccoz P,Romoli R,Persani L

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND/AIMS:Aldosterone and the mineralocorticoid receptor (MR) play a major role in sodium balance and blood pressure control. They are also involved in adipocyte metabolism. The aim of this study was to analyze the association between the MR p.I180V polymorphism with hypertension and markers of cardiovascular ris...

journal_title：Journal of endocrinological investigation

authors： Fernandes-Rosa FL,Bueno AC,de Souza RM,de Castro M,dos Santos JE,Foss MC,Zennaro MC,Bettiol H,Barbieri MA,Antonini SR

更新日期：2010-07-01 00:00:00

abstract：:The diagnosis of growth hormone (GH) deficiency (GHD) is currently based on failure to increase plasma GH levels to an arbitrary cutoff point of 7 or 10 micrograms/l in response to two provocative stimuli. False negative responses to these tests, however, frequently occur thus reducing their diagnostic reliability. Th...

journal_title：Journal of endocrinological investigation

authors： Ghigo E,Imperiale E,Boffano GM,Mazza E,Bellone J,Arvat E,Procopio M,Goffi S,Barreca A,Chiabotto P

更新日期：1990-04-01 00:00:00

abstract：UNLABELLED:Hexarelin (HEX) is a synthetic hexapeptide with strong GH-stimulating activity. We evaluated GH response (expressed as maximum value after stimulus [Cmax] and as area under the curve [AUC]) to HEX at the doses of 1 microg/kg i.v. (HEX 1) and 2 microg/kg i.v. (HEX 2), in comparison with the responses to GHRH ...

journal_title：Journal of endocrinological investigation

authors： Guzzaloni G,Grugni G,Morabito F

更新日期：1999-05-01 00:00:00

abstract：:A study of the effects of salmon calcitonin (sCT) infusion on blood sugar and serum insulin levels under basal conditions and after intravenous glucose load in normal subjects is reported. Under basal conditions, a 30 min infusion of sCT at approximately a rate of 1 U/min produced a highly significant increase in the ...

journal_title：Journal of endocrinological investigation

authors： Petralito A,Lunetta M,Liuzzo A,Fiore CE,Heynen G

更新日期：1979-04-01 00:00:00

abstract：OBJECTIVE:Elimination of thyroid antigens by total thyroid ablation (TTA), namely, thyroidectomy followed by radioiodine, may be beneficial for Graves' Orbitopathy (GO). TTA is usually performed with a 131I dose of 30 mCi. In Italy, this dose must be followed by a 24-h protected hospitalization, with increase in the wa...

journal_title：Journal of endocrinological investigation

authors： Leo M,Sabini E,Ionni I,Sframeli A,Mazzi B,Menconi F,Molinaro E,Bianchi F,Brozzi F,Santini P,Elisei R,Nardi M,Vitti P,Marcocci C,Marinò M

更新日期：2018-03-01 00:00:00

abstract：:The aim of this study was to assess the early insulin secretion and insulin action of healthy non-diabetic Hispanic-Mexican subjects with and without family history of Type 2 diabetes (FHD). One hundred and twenty non-relative subjects were compared against 115 first-degree relatives of individuals with Type 2 diabete...

journal_title：Journal of endocrinological investigation

authors： Guerrer-Romer F,Rodríguez-Morán M,González-Ortiz M,Martínez-Abundis E

更新日期：2001-09-01 00:00:00

abstract：PURPOSE:Aims of this study were to evaluate the agreement between the short and long versions of the International Physical Activity Questionnaire (IPAQ: Italian versions), their reproducibility (agreement and reliability) and construct validity (relative to pedometry) in a clinical population. METHODS:Ninety patients...

journal_title：Journal of endocrinological investigation

authors： Minetto MA,Motta G,Gorji NE,Lucini D,Biolo G,Pigozzi F,Portincasa P,Maffiuletti NA

更新日期：2018-03-01 00:00:00

abstract：:It has recently been suggested that the classical routine of glucocorticoid administration before and after transsphenoidal surgery (TSS) in Cushing's disease (CD) patients may not be necessary, since it is likely that peritumoral normal corticotrophs are not completely suppressed during this period. We compared the d...

journal_title：Journal of endocrinological investigation

authors： Pimentel-Filho FR,Silva ME,Nogueira KC,Berger K,Cukiert A,Liberman B

更新日期：2005-06-01 00:00:00

abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

journal_title：Journal of endocrinological investigation

authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

更新日期：2000-09-01 00:00:00

abstract：:GH secretion in acromegaly was studied in 8 patients before and during treatment with SMS 201-995, a somatostatin analogue, 100 micrograms twice daily, by evaluating GH day profiles and GH suppressibility after oral glucose tolerance tests (OGTT). Normalization of GH secretion, estimated by OGTT, was only observed in ...

journal_title：Journal of endocrinological investigation

authors： van Liessum PA,Pieters GF,Smals AG,Swinkels LM,Benraad TJ,Kloppenborg PW

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:Blepharophimosis syndrome (BPES) is an autosomal dominant genetic condition resulting from heterozygous mutations in the FOXL2 gene and clinically characterized by an eyelid malformation associated (type I) or not (type II) with premature ovarian failure. The distinction between the two forms is critical for ...

journal_title：Journal of endocrinological investigation

authors： Nuovo S,Passeri M,Di Benedetto E,Calanchini M,Meldolesi I,Di Giacomo MC,Petruzzi D,Piemontese MR,Zelante L,Sangiuolo F,Novelli G,Fabbri A,Brancati F

更新日期：2016-02-01 00:00:00

abstract：:The pathogenesis of human obesity is the result of dysregulation of the reciprocal relationship between food intake and energy expenditure (EE), which influences daily energy balance and ultimately leads to weight gain. According to principles of energy homeostasis, a relatively lower EE in a setting of energy balance...

journal_title：Journal of endocrinological investigation

authors： Piaggi P,Vinales KL,Basolo A,Santini F,Krakoff J

更新日期：2018-01-01 00:00:00

abstract：:The usefulness of solubilized TSH-receptor for measuring TSH and TSH-displacing antibodies (TDA) in a radioligand receptor assay (RRA) was investigated. Crude thyroid membranes were solubilized with Triton X-100. A soluble protein fraction was isolated by DEAE-Sephadex A-50 ion-exchange chromatography. The binding of ...

journal_title：Journal of endocrinological investigation

authors： Kotulla P,Schleusener H

更新日期：1981-04-01 00:00:00

abstract：:Among the several antigens involved in autoimmune thyroid diseases, the microsomal antigen has been recently identified as the human thyroid peroxidase (TPO). The availability of highly purified TPO and anti-TPO monoclonal antibody (mAb) allowed us to study in more details anti-TPO autoimmune antibodies (aAb) and thei...

journal_title：Journal of endocrinological investigation

authors： Czarnocka B,Ruf J,Ferrand M,Lissitzky S,Carayon P

更新日期：1986-04-01 00:00:00

abstract：:In 1992 a significant relationship between bone turnover and the vitamin D receptor (VDR) genotype was reported in Australian subjects of UK-Irish decent. Since then, several groups have investigated the relationship between VDR and other bone-related genotypes, bone mass and bone turnover in several populations. Howe...

journal_title：Journal of endocrinological investigation

authors： Sheehan D,Bennett T,Cashman KD

更新日期：2001-04-01 00:00:00

abstract：:Liver function is well maintained with increasing age. The aim of our study was to investigate if long-term moderate (

journal_title：Journal of endocrinological investigation

authors： Pinzani P,Petruzzi E,Orlando C,Malentacchi F,Petruzzi I,Pazzagli M,Masotti G

更新日期：2005-01-01 00:00:00

abstract：:Graves' disease (GD) is the most prevalent cause of thyrotoxicosis in children. Because spontaneous and lasting resolution of this condition occurs in only a minority of patients, most pediatric patients with GD will need radioactive iodine treatment (131I) or thyroidectomy. Whereas the medication propylthiouracil (PT...

journal_title：Journal of endocrinological investigation

authors： Rivkees SA

更新日期：2016-11-01 00:00:00

abstract：:Hypocalcemia associated with labor and lactation is a rare condition reported previously in patients with hypovitaminosis D. We here describe a case of a young woman in whom symptomatic severe hypocalcemia appeared after her second delivery, early in lactation. At the end of lactation the condition worsened. We review...

journal_title：Journal of endocrinological investigation

authors： Durst R,Meirovitz A,Gross D,Kolker O,Muszkat M

更新日期：2002-06-01 00:00:00

abstract：:The autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by diverse mutations in one allele of the gene that encodes the arginine vasopressin (AVP) precursor protein, AVP-neurophysin II (AVP-NP II). Most of the mutations identified so far are located in either the signal peptide or NP II ...

journal_title：Journal of endocrinological investigation

authors： Kobayashi H,Fujisawa I,Ikeda K,Son C,Iwakura T,Yoshimoto A,Kasahara M,Ishihara T,Ogawa Y

更新日期：2006-03-01 00:00:00

abstract：:Serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and prolactin (PRL) responses to exposure to sea-level altitude (LA) were examined in 13 eugonadal males, age 21-22 yr, 3 and 5 days after residing at LA and on the second day of return to basal altitude 90 days later. After 3 days at the...

journal_title：Journal of endocrinological investigation

authors： Ajlouni KM,Sliman NA,Najdawi A,Abu-Hajir MM,Arnaout MA

更新日期：1988-09-01 00:00:00