Abstract:
OBJECTIVES:The main purpose of this study was to investigate whether carotid artery stenting (CAS) plus medicine in patients with severe carotid artery stenosis provide a better long-term blood pressure (BP) control compared to other medical treatments alone. The other aim was to explore the correlation between post-CAS hypotension within 6 h and long-term BP reductions after CAS. MATERIALS AND METHODS:Patients with severe carotid stenosis were recruited either in the CAS group or in the medication group. BPs and the number of classes of antihypertensive agents were recorded at baseline, 6, and 12 months. Extra BP information was collected at 6 h, 3 days, and 1 month after CAS. Univariate and multivariate linear regressions were performed to test the relationship of BP changes among CAS and medication groups after 6 and 12 months of follow-up. Univariate linear regressions were also used to determine the correlations between the mean or maximal systolic BP (SBP) reductions at 6 h and 1 year post-CAS. RESULTS:In total, 72 members in the CAS group and 82 members in the medication group were recruited. Compared with the medication group, patients in the CAS group had greater BP reductions at 6 and 12 months of follow-up after adjusting for confounding factors (13.56 mmHg at 6 months, P=0.0002; 16.98 mmHg at 12 months, P<0.0001). This study also shows significant positive correlations between the mean or maximal SBP reductions 6 h post-CAS and SBP reductions 1 year post-CAS (β =0.20±0.07, P=0.0067 and β =0.47±0.10, P<0.0001, respectively). CONCLUSION:As compared to medical treatment alone, CAS may provide significant beneficial effect on long-term BP control 1 year post-CAS. Furthermore, SBP reductions 6 h post-CAS may predict the SBP reductions 1 year post-CAS.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Chang A,Hung HF,Hsieh FI,Chen WH,Yeh HL,Yeh JH,Chiu HC,Lien LMdoi
10.2147/CIA.S122352subject
Has Abstractpub_date
2017-01-06 00:00:00pages
103-109eissn
1176-9092issn
1178-1998pii
cia-12-103journal_volume
12pub_type
杂志文章abstract:Background:Disc degeneration (DD) is one of the common diseases worldwide, which deeply influences normal life and leads to excruciating pain. However, an effective treatment for DD is still not identified. Method:The present study systemically examined the effect of melatonin on annulus fibrosus (AF) cells of patient...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S193765
更新日期:2019-03-28 00:00:00
abstract:Background:Functional dependence (FD) and vitamin D deficiency are common conditions in older adults. However, little is known about the relationship between FD and serum vitamin D status in centenarians. The current study was designed to evaluate the prevalence of FD and examine its relationship with serum vitamin D s...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S182318
更新日期:2018-10-17 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S80668
更新日期:2015-03-27 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S183893
更新日期:2018-12-19 00:00:00
abstract:Purpose:Vestibular rehabilitation (VR) using posturography systems has proved useful in improving balance among elderly patients with postural instability. However, its high cost hinders its use. The objective of this study is to assess whether two different protocols of VR with posturography, one of them longer (ten s...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S263302
更新日期:2020-06-26 00:00:00
abstract::Prevention of dementia is a public health priority. Physical activity (PA) can reduce the risk of dementia, but the majority of people remain sedentary. We conducted a multicenter controlled study with older adults (60+ years). We hypothesized that an evidence-based PA intervention - GEhen, Spielen und Tanzen Als Lebe...
journal_title:Clinical interventions in aging
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2147/CIA.S141163
更新日期:2017-12-14 00:00:00
abstract:OBJECTIVE:To investigate the long-term effects of three antiarthritics, namely dexamethasone, celecoxib, and methotrexate on the histology and metabolism of intact bone tissue in rats. METHODS:Thirty-two 12-week-old healthy female Sprague Dawley rats were randomly allocated into four groups: 1) control (saline, daily)...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S85225
更新日期:2015-08-05 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S211328
更新日期:2019-08-02 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/cia.s1632
更新日期:2007-01-01 00:00:00
abstract::Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S15711
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:No conventional creatinine- or cystatin C-based glomerular filtration rate (GFR) estimation equation performed consistently outstandingly in elderly Chinese in our previous studies. This research aimed to further evaluate the performance of some recently proposed estimation equations based on creatinine and ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S68801
更新日期:2014-09-11 00:00:00
abstract:Objective:The objective involved the analysis of the efficiency of the Program of Movement Recreation of Elderly People (PMREP) exercise program expressed in terms of the stabilography measures and coactivation of muscles in women in the age group of 60-70 years. The assumption that was assumed stems from theoretical i...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S167782
更新日期:2018-09-12 00:00:00
abstract::Avoiding medications in which the risks outweigh the benefits in the elderly patient is a challenge for physicians, and different criteria to identify inappropriate prescription (IP) exist to aid prescribers. Definition of IP indicators in the Italian geriatric population affected by cardiovascular disease and chronic...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S137403
更新日期:2017-10-19 00:00:00
abstract:BACKGROUND:Demand for nursing and social services may vary depending on the socio-demographic variables, health status, receipt of formal and informal care provided, and place of residence. OBJECTIVES:To conduct a comparative analysis of the expectations of older people from urban, rural, and institutional environment...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S72534
更新日期:2015-02-02 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,meta分析
doi:10.2147/CIA.S210062
更新日期:2019-07-12 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S80997
更新日期:2015-08-19 00:00:00
abstract:Background:Multiple cranial dural arteriovenous fistulas (dAVFs) are considered to be an uncommon vascular condition. dAVFs usually manifest with vague symptoms, which are related to the site of occurrence of the lesion and present with complex angio-architectural features, which in turn can render treatment procedures...
journal_title:Clinical interventions in aging
pub_type:
doi:10.2147/CIA.S277762
更新日期:2020-12-08 00:00:00
abstract:Background:Transcutaneous electrical nerve stimulation (TENS) is a noninvasive modality which may be used to reduce acute postoperative pain. Intense perioperative pain within the first few days after hip fracture surgery is common and is related to negative consequences such as restricted and delayed ambulation. Obje...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S203658
更新日期:2019-10-29 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S63596
更新日期:2014-07-22 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S77433
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S141518
更新日期:2017-08-08 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S64718
更新日期:2014-10-13 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S85216
更新日期:2015-07-07 00:00:00
abstract:Introduction:Paternalism, assuming control of aged care, is a widespread orientation in older adults care. Paternalistic attitudes and practices are commonly understood as a threat to the freedom and autonomy of a person, making patients more dependent. Therefore, the reduction of these attitudes and behaviors is a pri...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S213644
更新日期:2019-08-26 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S57714
更新日期:2014-03-17 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S32356
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Gerontological research aims at understanding factors that are crucial for mediating "successful aging". This term denotes the absence of significant disease and disabilities, maintenance of high levels of physical and cognitive function, and preservation of social and productive activities. Preservation of ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S15433
更新日期:2011-01-01 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S200269
更新日期:2019-06-28 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S74755
更新日期:2015-02-26 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S135364
更新日期:2017-05-26 00:00:00