Abstract:
PURPOSE:Macular hole (MH) is part of a group of age-related degenerative diseases characterized by pathology of vitreomacular interface. Similarly, neovascular age-related macular degeneration (nAMD) affects older patients and is a leading cause of irreversible visual loss. The purpose of this case series is to describe the development of full-thickness MH in patients with nAMD, following antivascular endothelial growth factor (anti-VEGF) treatment. METHODS:Participants in this case series were four patients with nAMD, who received anti-VEGF injections with variable therapeutic response to treatment. Patients were examined at baseline (when AMD was diagnosed) and monthly thereafter. The examination included visual acuity measurement, slit-lamp biomicroscopy, and optical coherence tomography. RESULTS:All patients were found to develop full-thickness MH within 1-4 months after the last anti-VEGF injection, even in the absence of pre-existing vitreomacular interface abnormalities in some cases. The median number of injections before the MH formation was 3. CONCLUSION:MH formation may represent an adverse effect of anti-VEGF treatment in patients with nAMD and could be also coexisting pathology with nAMD in older individuals.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Kabanarou SA,Xirou T,Mangouritsas G,Garnavou-Xirou C,Boutouri E,Gkizis I,Chatziralli Idoi
10.2147/CIA.S135364subject
Has Abstractpub_date
2017-05-26 00:00:00pages
911-915eissn
1176-9092issn
1178-1998pii
cia-12-911journal_volume
12pub_type
杂志文章abstract:Objective:The aim of this study was to evaluate the effects of dental status and chewing efficiency on the oral-health-related quality of life (OHRQoL) of nursing-home residents. Materials and Methods:The study was conducted in nine nursing homes. All eligible participants were included, and general and medical data, ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S273671
更新日期:2020-11-11 00:00:00
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journal_title:Clinical interventions in aging
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doi:10.2147/CIA.S234938
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S151453
更新日期:2018-03-01 00:00:00
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journal_title:Clinical interventions in aging
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pub_type: 杂志文章,评审
doi:10.2147/CIA.S54630
更新日期:2015-02-11 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2147/CIA.S60838
更新日期:2014-04-10 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S55972
更新日期:2014-02-14 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S178393
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pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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更新日期:2019-01-15 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
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更新日期:2017-11-07 00:00:00