The relationship between cholesterol and cognitive function is homocysteine-dependent.

abstract：Aim:To contribute to the knowledge about the mechanisms involved in aortic stiffness due to ageing. Materials and Methods:Aortic rings from young (1.5±0.5 months, 0.8±0.2 kg), adult (6±0.5 months, 2.7±0.5 kg) and old (28±8 months, 3.2±0.8 kg) male New Zealand rabbits were used to evaluate: 1) intima-media thickness by...

journal_title：Clinical interventions in aging

authors： Cupitra NI,Calderón JC,Narvaez-Sanchez R

更新日期：2020-04-20 00:00:00

abstract：Background:Aging is a spontaneous and inevitable phenomenon of biology, which can lead to the gradual deterioration of tissues and organs. One of the age-related deterioration processes is immunosenescence, which leads to changes in the function of immune systems, including immune cells and associated cytokines. A prop...

journal_title：Clinical interventions in aging

authors： Li X,Gao J,Yu Z,Jiang W,Sun W,Yu C,Sun J,Wang C,Chen J,Jing S,Li H

更新日期：2020-01-29 00:00:00

abstract：:Background and objective: Oxidative stress has been demonstrated to be a mechanism that leads to bone mass reduction, and according to many studies, serum uric acid (UA) is a strong endogenous antioxidant that can protect bone mineral density (BMD). To date, there have been no large-scale, cross-sectional studies base...

journal_title：Clinical interventions in aging

authors： Chen F,Wang Y,Guo Y,Wang J,Yang A,Lv Q,Liu Y,Ma G,Liu Y,Wang D

更新日期：2019-06-12 00:00:00

abstract：:Age remains the most powerful prognostic factor among glioblastoma (GBM) patients. Half of all patients with GBM are aged 65 years or older at the time of diagnosis, and the incidence rate of GBM in patients aged over 65 years is increasing rapidly. Median survival for elderly GBM patients is less than 6 months and re...

journal_title：Clinical interventions in aging

authors： Arvold ND,Reardon DA

更新日期：2014-02-21 00:00:00

abstract：PURPOSE:The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation. METHODS:Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or...

journal_title：Clinical interventions in aging

authors： Moschos MM,Chatziralli IP,Tsatsos M

更新日期：2015-08-24 00:00:00

abstract：OBJECTIVE:The best practice tariff (BPT) incentivizes hospitals in the England and Wales National Health Service to provide multiprofessional care to patients with hip fractures. The initial six targets included: 1) admission under consultant-led joint orthopedic-geriatric care, 2) multidisciplinary assessment protocol...

journal_title：Clinical interventions in aging

authors： Khan SK,Shirley MD,Glennie C,Fearon PV,Deehan DJ

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To report our experiences in changing from intravitreal bevacizumab to ranibizumab in age-related macular degeneration (AMD). DESIGN:Retrospective case series. PARTICIPANTS AND METHODS:We retrospectively reviewed the records of 34 patients (36 eyes) who were treated with monthly injections of intravitreal b...

journal_title：Clinical interventions in aging

authors： Karagiannis DA,Ladas ID,Parikakis E,Georgalas I,Kotsolis A,Amariotakis G,Soumplis V,Mitropoulos P

更新日期：2009-01-01 00:00:00

abstract：Background:Both aortic valve stenosis and aortic stiffness are moderators of arterio ventricular coupling and independent predictors of cardiovascular morbidity and mortality. Studies on the effect of transcatheter aortic valve implantation (TAVI) on aortic functional properties are limited. We performed a study to inv...

journal_title：Clinical interventions in aging

authors： Goudzwaard JA,Disegna E,de Ronde-Tillmans MJ,Lenzen MJ,de Jaegere PP,Mattace-Raso FU

更新日期：2019-08-02 00:00:00

abstract：BACKGROUND:Rheumatic diseases, irrespective of etiology and clinical course, influence different areas of a patient's life. Adapting to disability and limitations caused by an illness is very difficult for many patients. The main goal of a therapeutic procedure should be improvement of health-related quality of life (Q...

journal_title：Clinical interventions in aging

authors： Wysocka-Skurska I,Sierakowska M,Kułak W

更新日期：2016-11-28 00:00:00

abstract：:The percentage of the population described as elderly is growing, and a higher prevalence of multiple, chronic disease states must be managed concurrently. Healthcare practitioners must appropriately use medication for multiple diseases and avoid risks often associated with multiple medication use such as adverse effe...

journal_title：Clinical interventions in aging

authors： Bushardt RL,Massey EB,Simpson TW,Ariail JC,Simpson KN

更新日期：2008-01-01 00:00:00

abstract：Purpose:Vestibular rehabilitation (VR) using posturography systems has proved useful in improving balance among elderly patients with postural instability. However, its high cost hinders its use. The objective of this study is to assess whether two different protocols of VR with posturography, one of them longer (ten s...

journal_title：Clinical interventions in aging

authors： Soto-Varela A,Rossi-Izquierdo M,Del-Río-Valeiras M,Vaamonde-Sánchez-Andrade I,Faraldo-García A,Lirola-Delgado A,Santos-Pérez S

更新日期：2020-06-26 00:00:00

abstract：:The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermat...

journal_title：Clinical interventions in aging

authors： Humbert P,Dréno B,Krutmann J,Luger TA,Triller R,Meaume S,Seité S

更新日期：2016-02-12 00:00:00

abstract：:Osteoporosis is a condition causing significant morbidity and mortality in the elderly population worldwide. Age-related testosterone deficiency is the most important factor of bone loss in elderly men. Androgen can influence bone health by binding to androgen receptors directly or to estrogen receptors (ERs) indirect...

journal_title：Clinical interventions in aging

authors： Mohamad NV,Soelaiman IN,Chin KY

更新日期：2016-09-22 00:00:00

abstract：:Most patients with myelodysplastic syndromes (MDS) are elderly (median age range 65 to 70 years); as a consequence, the incidence and prevalence of these diseases are rising as the population ages. Physicians are often uncertain about how to identify patients who may benefit from specific treatment strategies. The Int...

journal_title：Clinical interventions in aging

authors： Ria R,Moschetta M,Reale A,Mangialardi G,Castrovilli A,Vacca A,Dammacco F

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Patients leaving the hospital are at increased risk of functional decline and hospital readmission. The Employee and Community Health service at Mayo Clinic in Rochester developed a care transition program (CTP) to provide home-based care services for medically complex patients. The study objective was to deter...

journal_title：Clinical interventions in aging

authors： Takahashi PY,Haas LR,Quigg SM,Croghan IT,Naessens JM,Shah ND,Hanson GJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to study the performance and reliability of a test of fast alternating forearm movements and its relationship with measures of lower extremity function in older women with dementia. METHODS:Fast alternating movements was studied in 26 female patients (mean age 81.7 ± 5.9 years) ...

journal_title：Clinical interventions in aging

authors： Bramell-Risberg E,Jarnlo GB,Elmståhl S

更新日期：2013-01-01 00:00:00

abstract：:We previously demonstrated the beneficial effects of a multisensory and cognitive stimulation program, consisting of 48 sessions, twice a week, to improve the cognition of elderly subjects living either in long-term care institutions (institutionalized - I) or in communities with their families (noninstitutionalized -...

journal_title：Clinical interventions in aging

authors： de Macedo LD,De Oliveira TC,Soares FC,Bento-Torres J,Bento-Torres NV,Anthony DC,Picanço-Diniz CW

更新日期：2015-08-19 00:00:00

abstract：Background:People living with dementia (PWD) and their informal caregivers often report difficulties in maintaining their usual activities. Several dyadic, psychosocial, activating interventions were developed to create insight into how to cope with limitations in a practical way and to increase skills for maintaining ...

journal_title：Clinical interventions in aging

authors： Leven NV,de Lange J,van der Ploeg ES,Pot AM

更新日期：2018-09-27 00:00:00

abstract：:Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes. Two major frailty models have been described in the literature. The frailty phenotype defines frai...

journal_title：Clinical interventions in aging

authors： Chen X,Mao G,Leng SX

更新日期：2014-03-19 00:00:00

abstract：Background:When considering the "joint as an organ", the tissues in a joint act as complementary components of an organ, and the "set point" is the cellular activity for homeostasis of the joint tissues. Even in the absence of injury, joint tissues have adaptive responses to processes, like aging and menopause, which r...

journal_title：Clinical interventions in aging

authors： Rollick NC,Lemmex DB,Ono Y,Reno CR,Hart DA,Lo IK,Thornton GM

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Older patients with acute myocardial infarction (AMI) usually have a poor prognosis, but whether this poor prognosis leads to high hospital costs remains unclear. This study investigated the clinical outcomes of and costs incurred by older patients with AMI and metabolic syndrome (MS) in hospital. METHODS A...

journal_title：Clinical interventions in aging

authors： Fan GQ,Fu KL,Jin CW,Wang XZ,Han L,Wang H,Zhong M,Zhang Y,Zhang W,Wang ZH

更新日期：2015-01-23 00:00:00

abstract：:Apligraf (Organogenesis, Canton, MA) is a bi-layered bioengineered skin substitute and was the first engineered skin US Food and Drug Administration (FDA)-approved to promote the healing of ulcers that have failed standard wound care. Constructed by culturing human foreskin-derived neonatal fibroblasts in a bovine typ...

journal_title：Clinical interventions in aging

authors： Zaulyanov L,Kirsner RS

更新日期：2007-01-01 00:00:00

abstract：:Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...

journal_title：Clinical interventions in aging

authors： Kawate H,Takayanagi R

更新日期：2011-01-01 00:00:00

abstract：Background:Postoperative functional training for fracture or osteoarthritis is mainly focused on functional self-exercise, which aims to recover the function of the lower limbs. Purpose:To compare the function and life quality recovery in patients with fracture or arthritis treated with novel muscle training device (N...

journal_title：Clinical interventions in aging

authors： Cai XY,Lin DQ,Xiao ZZ,Zhang DD,Lin Y,Chen HY,Xu YX,Zhou YH

更新日期：2020-11-18 00:00:00

abstract：Purpose:In this cross-sectional study, three clinical tools, the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI), for predicting primary osteoporosis (OP) were compared and ideal thresholds for omission of screening ...

journal_title：Clinical interventions in aging

authors： Zhang X,Lin J,Yang Y,Wu H,Li Y,Yang X,Fei Q

更新日期：2018-02-02 00:00:00

abstract：Objective:The number of long-term care (LTC) users and the associated expenditures in Japan are increasing dramatically. The national government recommends LTC prevention through activation of communities. However, there is no clear evidence of the effect of population-based comprehensive geriatric intervention program...

journal_title：Clinical interventions in aging

authors： Watanabe Y,Yamada Y,Yokoyama K,Yoshida T,Yoshinaka Y,Yoshimoto M,Tanaka Y,Itoi A,Yamagata E,Ebine N,Ishikawa-Takata K,Kimura M

更新日期：2018-05-24 00:00:00

abstract：Background:Physical exercise is associated with decreased cardiovascular disease (CVD) risk, but recent large-scale trials suggest that exercise alone is insufficient to reduce CVD events in high-risk older adults. Purpose:This pilot randomized clinical trial aimed to collect critical data on feasibility, safety, and ...

journal_title：Clinical interventions in aging

authors： Roberts LM,Jaeger BC,Baptista LC,Harper SA,Gardner AK,Jackson EA,Pekmezi D,Sandesara B,Manini TM,Anton SD,Buford TW

更新日期：2019-10-23 00:00:00

abstract：BACKGROUND:Aortic valve stenosis is common in the elderly, with a prevalence of nearly 3% in patients aged 75 years or older. Despite the fact that sleep-related breathing disorders (SRBD) are thought to be associated with cardiac disease, little is known about their prevalence in this patient cohort. The purpose of th...

journal_title：Clinical interventions in aging

authors： Keymel S,Hellhammer K,Zeus T,Merx M,Kelm M,Steiner S

更新日期：2015-09-07 00:00:00

abstract：PURPOSE:The effects of a multicomponent dyadic intervention on the mood, behavior, and physical health of people with dementia living in the community were evaluated in a randomized controlled trial. This multicomponent dyadic intervention is a translated and adapted version of an intervention that has been shown to be...

journal_title：Clinical interventions in aging

authors： Prick AE,de Lange J,Scherder E,Twisk J,Pot AM

更新日期：2016-03-31 00:00:00

abstract：Background:Transcutaneous electrical nerve stimulation (TENS) is a noninvasive modality which may be used to reduce acute postoperative pain. Intense perioperative pain within the first few days after hip fracture surgery is common and is related to negative consequences such as restricted and delayed ambulation. Obje...

journal_title：Clinical interventions in aging

authors： Elboim-Gabyzon M,Andrawus Najjar S,Shtarker H

更新日期：2019-10-29 00:00:00