Changing from bevacizumab to ranibizumab in age-related macular degeneration. Is it safe?

abstract：Purpose:The role of biomarkers in the prediction of acute ischemic stroke (AIS) outcome or response to thrombolytic therapy (with recombinant tissue plasminogen activator [rt-PA]) remains limited. The aim of this study was to evaluate whether mean platelet volume (MPV) could predict short-term functional outcome in pat...

journal_title：Clinical interventions in aging

authors： Staszewski J,Pogoda A,Data K,Walczak K,Nowocień M,Frankowska E,Stępień A

更新日期：2019-02-27 00:00:00

abstract：:[This corrects the article on p. 1237 in vol. 13, PMID: 30034227.]. ...

journal_title：Clinical interventions in aging

authors：

更新日期：2018-09-05 00:00:00

abstract：Objective:The aim of this study was to compare the perceived oral health of elderly persons and the clinical reality of their oral status. Background:Persons aged over 60 have considerable need for oral health care; a need that increases over time. However, this population appears to be unaware of their state of oral ...

journal_title：Clinical interventions in aging

authors： Maille G,Saliba-Serre B,Ferrandez AM,Ruquet M

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Digoxin is a frequently prescribed drug, particularly in the elderly population, in which there is an increased prevalence of atrial fibrillation and cardiac failure. With its complex pharmacokinetic profile and narrow therapeutic index, use of digoxin requires regular monitoring of blood levels. Recent evid...

journal_title：Clinical interventions in aging

authors： Zhao L,Yang P,Li P,Wang X,Qin W,Zhang X

更新日期：2014-07-22 00:00:00

abstract：:Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due...

journal_title：Clinical interventions in aging

authors： Ughi N,Crotti C,Ingegnoli F

更新日期：2016-03-14 00:00:00

abstract：Background:Postoperative functional training for fracture or osteoarthritis is mainly focused on functional self-exercise, which aims to recover the function of the lower limbs. Purpose:To compare the function and life quality recovery in patients with fracture or arthritis treated with novel muscle training device (N...

journal_title：Clinical interventions in aging

authors： Cai XY,Lin DQ,Xiao ZZ,Zhang DD,Lin Y,Chen HY,Xu YX,Zhou YH

更新日期：2020-11-18 00:00:00

abstract：BACKGROUND:Early-stage chronic kidney disease has been suggested to be correlated with cognitive decline, but the association has rarely been explored in the oldest old. SUBJECTS AND METHODS:This prospective study included 284 Chinese participants aged 80 years or older with serum creatinine levels <150 µmol/L. The me...

journal_title：Clinical interventions in aging

authors： Bai K,Pan Y,Lu F,Zhao Y,Wang J,Zhang L

更新日期：2017-07-04 00:00:00

abstract：:Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes. Two major frailty models have been described in the literature. The frailty phenotype defines frai...

journal_title：Clinical interventions in aging

authors： Chen X,Mao G,Leng SX

更新日期：2014-03-19 00:00:00

abstract：:Avoiding medications in which the risks outweigh the benefits in the elderly patient is a challenge for physicians, and different criteria to identify inappropriate prescription (IP) exist to aid prescribers. Definition of IP indicators in the Italian geriatric population affected by cardiovascular disease and chronic...

journal_title：Clinical interventions in aging

authors： Lucenteforte E,Lombardi N,Vetrano DL,La Carpia D,Mitrova Z,Kirchmayer U,Corrao G,Lapi F,Mugelli A,Vannacci A

更新日期：2017-10-19 00:00:00

abstract：:The purpose of this study was to determine the test-retest reliability of the International Physical Activity Questionnaire (IPAQ) for older adults in Serbia. Six hundred and sixty older adults (352 men, 53%; 308 women, 47%; mean age 67.65±5.76 years) participated in the study. To examine test-retest reliability, the ...

journal_title：Clinical interventions in aging

authors： Milanović Z,Pantelić S,Trajković N,Jorgić B,Sporiš G,Bratić M

更新日期：2014-04-07 00:00:00

abstract：:Alzheimer's disease (AD) is the most common cause of dementia affecting nearly 18 million people around the world and 4.5 million in the US. It is a progressive neurodegenerative condition that is estimated to dramatically increase in prevalence as the elderly population continues to grow. As the cognitive and neurops...

journal_title：Clinical interventions in aging

authors： Shah S,Reichman WE

更新日期：2006-01-01 00:00:00

abstract：Background:Myocardial infarction (MI) is a common cause of death worldwide. It is characterized by coronary artery occlusion that causes ischemia and hypoxia of myocardial cells, leading to irreversible myocardial damage. Materials and Methods:To explore potential targets for treatment of MI, we reorganized and analyz...

journal_title：Clinical interventions in aging

authors： Yu YW,Xue YJ,Qian LL,Chen Z,Que JQ,Huang KY,Liu S,Weng YB,Rong FN,Ji KT,Zeng JN

更新日期：2020-12-01 00:00:00

abstract：:Vitamin E has been proposed as a potential clinical intervention for Alzheimer's disease (AD) given the plausibility of its various biological functions in influencing the neurodegenerative processes associated with the condition. The tocopherol and tocotrienol isoforms of vitamin E have multiple properties including ...

journal_title：Clinical interventions in aging

authors： Browne D,McGuinness B,Woodside JV,McKay GJ

更新日期：2019-07-18 00:00:00

abstract：Background:Disc degeneration (DD) is one of the common diseases worldwide, which deeply influences normal life and leads to excruciating pain. However, an effective treatment for DD is still not identified. Method:The present study systemically examined the effect of melatonin on annulus fibrosus (AF) cells of patient...

journal_title：Clinical interventions in aging

authors： Hai B,Ma Y,Pan X,Yong L,Liang C,He G,Yang C,Zhu B,Liu X

更新日期：2019-03-28 00:00:00

abstract：OBJECTIVE:The objectives of this study were to assess the elongation of the styloid process on digital panoramic radiographs and to evaluate the prevalence of the elongation according to age, sex and types. PATIENTS AND METHODS:Digital panoramic radiographs of 198 geriatric edentulous patients were analyzed. The radio...

journal_title：Clinical interventions in aging

authors： AlZarea BK

更新日期：2017-03-30 00:00:00

abstract：:Bone remodeling requires a precise balance between resorption and formation. It is a complex process that involves numerous factors: hormones, growth factors, vitamins, and cytokines, and notably osteoprotegerin (OPG) and receptor activator for nuclear factor-κB (RANK) ligand. The signaling pathway OPG/RANK/RANKL is k...

journal_title：Clinical interventions in aging

authors： Trouvin AP,Goëb V

更新日期：2010-11-19 00:00:00

abstract：OBJECTIVE:To investigate both short-term and long-term therapeutic efficacy and safety of carotid artery stenting (CAS) and carotid artery endarterectomy (CEA) for elderly patients with severe and symptomatic carotid artery stenosis. METHODS:PubMed, EMBASE, Cochrane Library, Clinical Trials Register Centers, and Googl...

journal_title：Clinical interventions in aging

authors： Ouyang YA,Jiang Y,Yu M,Zhang Y,Huang H

更新日期：2015-10-28 00:00:00

abstract：Background:Tinnitus and dizziness are frequent in old age and often seen as concomitant symptoms in patients with dementia. In earlier clinical trials, Ginkgo biloba extract EGb 761® was found to alleviate tinnitus and dizziness in elderly patients. Consequently, a meta-analysis was conducted to evaluate the effects of...

journal_title：Clinical interventions in aging

authors： Spiegel R,Kalla R,Mantokoudis G,Maire R,Mueller H,Hoerr R,Ihl R

更新日期：2018-06-13 00:00:00

abstract：:Hypernatremia in the geriatric population is a common disorder associated with significant morbidity and mortality. Older people are predisposed to developing hypernatremia because of age-related physiologic changes such as decreased thirst drive, impaired urinary concentrating ability, and reduced total body water. M...

journal_title：Clinical interventions in aging

authors： Shah MK,Workeneh B,Taffet GE

更新日期：2014-11-19 00:00:00

abstract：Background:Cognitive function has been suggested to be correlated with mortality, while studies regarding the association among the very elderly population with chronic kidney disease (CKD) are extremely limited. Aim:To explore the association between cognitive function and mortality among the very elderly Chinese pop...

journal_title：Clinical interventions in aging

authors： Bai K,Pan Y,Lu F,Zhao Y,Wang F,Zhang L

更新日期：2018-10-18 00:00:00

abstract：BACKGROUND:Endovascular option has been proposed for a very limited and selected number of Stanford type A aortic dissection (TAAD) patients. We have performed a computed tomography (CT)-based TAAD study to explore appropriate endograft configurations for the ascending aortic pathology. METHODS:TAAD patients treated w...

journal_title：Clinical interventions in aging

authors： Zhang Y,Tang H,Zhou J,Liu Z,Liu C,Qiao T,Zhou M

更新日期：2016-07-14 00:00:00

abstract：Background:Depression in the elderly is a serious and often underdiagnosed psychiatric disorder that has been linked to adverse outcomes in the hospital setting. This study aims to evaluate the prevalence of depressive symptoms and associated factors among elderly hospital inpatients. Methods:The cross-sectional study...

journal_title：Clinical interventions in aging

authors： Zou C,Chen S,Shen J,Zheng X,Wang L,Guan L,Liu Q,Yang Y

更新日期：2018-09-13 00:00:00

abstract：OBJECTIVE:To estimate the value of the different thromboelastogram indices for predicting hemorrhage and vascular obstruction in an elderly population. METHODS:This was a prospective cohort study of patients 65 years and older without hemato-logic disorders who received thromboelastography (TEG) examination at the Chi...

journal_title：Clinical interventions in aging

authors： Zheng Q,Fu S,Chen D,Li X,Li Y,Li Y,Yu J,Gong M,Bai J

更新日期：2013-01-01 00:00:00

abstract：:Dementia is one of the most important public health problems as a result of the rapid increase in the number of elderly persons worldwide. Improvement of prevention strategies and caring for people with dementia should be undertaken. We performed a door-to-door study to screen all subjects aged 50 years and older (n=4...

journal_title：Clinical interventions in aging

authors： El Tallawy HN,Farghly WM,Badry R,Rageh TA,Shehata GA,Hakeem M NA,Abd El Hamed M,Sayd MA,Hamed Y,Kandil MR

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To study the feasibility of first, reaching functionally declined, but still independent older persons at risk of falls through their general practitioner (GP) and second, to reduce their physiological and psychological fall risk factors with a complex exercise intervention. We investigated the effects of a 16-...

journal_title：Clinical interventions in aging

authors： Freiberger E,Blank WA,Salb J,Geilhof B,Hentschke C,Landendoerfer P,Halle M,Siegrist M

更新日期：2013-01-01 00:00:00

abstract：:In this case study of an unique instance, effects of medium-energy, high-focused extracorporeal generated shock waves (ESW) onto the skin and the underlying fat tissue of a cellulite afflicted, 50-year-old woman were investigated. The treatment consisted of four ESW applications within 21 days. Diagnostic high-resolut...

journal_title：Clinical interventions in aging

authors： Kuhn C,Angehrn F,Sonnabend O,Voss A

更新日期：2008-01-01 00:00:00

abstract：:The objective of this study was to evaluate cardiac autonomic control and muscle vasodilation response during isometric exercise in sedentary and physically active older adults. Twenty healthy participants, 10 sedentary and 10 physically active older adults, were evaluated and paired by gender, age, and body mass inde...

journal_title：Clinical interventions in aging

authors： Sarmento AO,Santos ADC,Trombetta IC,Dantas MM,Oliveira Marques AC,do Nascimento LS,Barbosa BT,Dos Santos MR,Andrade MDA,Jaguaribe-Lima AM,Brasileiro-Santos MDS

更新日期：2017-06-28 00:00:00

abstract：:Evidence of epidemiological associations of vitamins and disease states have been found for nine vitamins. In observational studies, people with a high intake of antioxidant vitamins by regular diet or as food supplements generally have a lower risk of major chronic disease, such as myocardial infarction or stroke, th...

journal_title：Clinical interventions in aging

authors： Thomas DR

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (F...

journal_title：Clinical interventions in aging

authors： Galvin JE,Tolea MI,George N,Wingbermuehle C

更新日期：2014-04-10 00:00:00

abstract：OBJECTIVE:To evaluate the impact of chronic obstructive pulmonary disease (COPD) on left ventricular (LV) diastolic function in hospitalized elderly patients. METHODS:This was a case-control observational study of 148 consecutive hospitalized elderly patients (≥65 years old): 73 subjects without COPD as controls and 7...

journal_title：Clinical interventions in aging

authors： Huang YS,Feng YC,Zhang J,Bai L,Huang W,Li M,Sun Y

更新日期：2014-12-19 00:00:00