Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports.

Abstract:

:Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.

journal_name

Clin Interv Aging

authors

Ughi N,Crotti C,Ingegnoli F

doi

10.2147/CIA.S102577

subject

Has Abstract

pub_date

2016-03-14 00:00:00

pages

307-11

eissn

1176-9092

issn

1178-1998

pii

cia-11-307

journal_volume

11

pub_type

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