Abstract:
:Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Ughi N,Crotti C,Ingegnoli Fdoi
10.2147/CIA.S102577subject
Has Abstractpub_date
2016-03-14 00:00:00pages
307-11eissn
1176-9092issn
1178-1998pii
cia-11-307journal_volume
11pub_type
杂志文章abstract::The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermat...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S96232
更新日期:2016-02-12 00:00:00
abstract:BACKGROUND:The purpose of this work was to study the performance and reliability of a test of fast alternating forearm movements and its relationship with measures of lower extremity function in older women with dementia. METHODS:Fast alternating movements was studied in 26 female patients (mean age 81.7 ± 5.9 years) ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S37733
更新日期:2013-01-01 00:00:00
abstract:Background:Both aortic valve stenosis and aortic stiffness are moderators of arterio ventricular coupling and independent predictors of cardiovascular morbidity and mortality. Studies on the effect of transcatheter aortic valve implantation (TAVI) on aortic functional properties are limited. We performed a study to inv...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S211328
更新日期:2019-08-02 00:00:00
abstract::In this case study of an unique instance, effects of medium-energy, high-focused extracorporeal generated shock waves (ESW) onto the skin and the underlying fat tissue of a cellulite afflicted, 50-year-old woman were investigated. The treatment consisted of four ESW applications within 21 days. Diagnostic high-resolut...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/cia.s2334
更新日期:2008-01-01 00:00:00
abstract::Apligraf (Organogenesis, Canton, MA) is a bi-layered bioengineered skin substitute and was the first engineered skin US Food and Drug Administration (FDA)-approved to promote the healing of ulcers that have failed standard wound care. Constructed by culturing human foreskin-derived neonatal fibroblasts in a bovine typ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/ciia.2007.2.1.93
更新日期:2007-01-01 00:00:00
abstract::Osteoporosis and fragility fractures are relevant health issues because of their impact in terms of morbidity, mortality, and socioeconomic burden. Despite this alarming scenario, both underdiagnosis and undertreatment are common features of osteoporotic patients, particularly those who have already sustained a fragil...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S242038
更新日期:2020-03-26 00:00:00
abstract::The most compelling reason and primary goal of treating actinic keratoses is to prevent malignant transformation into invasive squamous cell carcinoma, and although there are well established guidelines outlining treatment modalities and regimens for squamous cell carcinoma, the more commonly encountered precancerous ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S31930
更新日期:2013-01-01 00:00:00
abstract::Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S15711
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:This validation study aims to examine Cornell Scale for Depression in Dementia (CSDD) items in terms of the agreement found between residents and caregivers, and also to compare alternative models of the Thai version of the CSDD. PATIENTS AND METHODS:A cross-sectional study was conducted of 84 elderly resident...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S45201
更新日期:2013-01-01 00:00:00
abstract::Fluctuating Parkinson's disease (PD) represents a clinical management challenge. The primary utility of levodopa in patients with PD is moderated by the "wearing off" phenomena seen with long-term use. COMT inhibitors slow down the rapid metabolism of levodopa, resulting in a more-sustained response to dopaminergic th...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/ciia.2006.1.4.317
更新日期:2006-01-01 00:00:00
abstract:Background:Disc degeneration (DD) is one of the common diseases worldwide, which deeply influences normal life and leads to excruciating pain. However, an effective treatment for DD is still not identified. Method:The present study systemically examined the effect of melatonin on annulus fibrosus (AF) cells of patient...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S193765
更新日期:2019-03-28 00:00:00
abstract:Background:A thorough analysis of the capability for self-care in patients with heart failure (HF) reduces the frequency of hospitalizations that are caused by decompensation. The aim of the study was to assess the effect of the method of therapy for HF, the degree of the acceptance of illness, and the occurrence of fr...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S178393
更新日期:2018-10-08 00:00:00
abstract:OBJECTIVE:Routine measurement of the carotid intima-media thickness is not recommended in recent clinical practice guidelines for risk assessment of the first atherosclerotic cardiovascular disease (ASCVD) event (the definition of which includes acute coronary syndromes, a history of myocardial infarction, stable or un...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S85216
更新日期:2015-07-07 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the effect of two sessions of resistance exercise with different volumes on post-exercise hypotension, forearm blood flow, and forearm vascular resistance in hypertensive elderly subjects. METHODS:The study was conducted with ten hypertensive elderly (65±3 years, 28...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S53441
更新日期:2014-12-12 00:00:00
abstract:BACKGROUND:No conventional creatinine- or cystatin C-based glomerular filtration rate (GFR) estimation equation performed consistently outstandingly in elderly Chinese in our previous studies. This research aimed to further evaluate the performance of some recently proposed estimation equations based on creatinine and ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S68801
更新日期:2014-09-11 00:00:00
abstract::Vitamin E has been proposed as a potential clinical intervention for Alzheimer's disease (AD) given the plausibility of its various biological functions in influencing the neurodegenerative processes associated with the condition. The tocopherol and tocotrienol isoforms of vitamin E have multiple properties including ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S186760
更新日期:2019-07-18 00:00:00
abstract:PURPOSE:Cognitive screening upon hospital admission can provide important information about the patient's ability to process information during the inpatient stay. The Clock-in-the-Box (CIB) is a rapidly administered cognitive screening measure which has been previously validated with cognitive screening and neuropsych...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S118235
更新日期:2016-11-22 00:00:00
abstract:Purpose:Femoral neck fracture usually occurs in the geriatric population. Postoperative pneumonia (POP) is known to be devastated, and it is the most frequent complication among patients receiving surgical treatment for femoral neck fractures. However, whether patients who have hypoalbuminaemia are susceptible to the d...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S231736
更新日期:2019-11-13 00:00:00
abstract::The use of atypical antipsychotic drugs in the elderly has become wider and wider in recent years; in fact, these agents have novel receptor binding profiles, good efficacy with regard to negative symptoms, and reduced extrapyramidal symptoms. However, in recent years, the use of both conventional and atypical antipsy...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S63942
更新日期:2014-08-16 00:00:00
abstract:Background:Postoperative functional training for fracture or osteoarthritis is mainly focused on functional self-exercise, which aims to recover the function of the lower limbs. Purpose:To compare the function and life quality recovery in patients with fracture or arthritis treated with novel muscle training device (N...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S277118
更新日期:2020-11-18 00:00:00
abstract:OBJECTIVE:The main purpose of the investigation reported here was to analyze the effect of resistance training (RT) performed at different weekly frequencies on flexibility in older women. PARTICIPANTS AND METHODS:Fifty-three older women (≥60 years old) were randomly assigned to perform RT either two (n=28; group "G2x...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S77433
更新日期:2015-03-05 00:00:00
abstract:BACKGROUND:Life style and physical activity play a pivotal role in prevention and treatment of osteoporosis. The mechanism for better bone metabolism and improvement of physical disorders is not clear yet. Trace minerals such as Ca, Mn, Cu, and Zn are essential precursors for most vital biological process, especially t...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S100566
更新日期:2016-02-29 00:00:00
abstract:Objective:We studied the efficacy of zoledronic acid (ZOL) infusion on radiographic and clinical outcomes after percutaneous kyphoplasty (PKP) for elderly patients with osteoporotic thoracolumbar fractures (osteoporotic vertebral compression fractures [OVCFs]). Materials and methods:We retrospectively analyzed 95 elde...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S146871
更新日期:2018-05-04 00:00:00
abstract:Objective:We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy of cognitive stimulation therapy (CST) of different durations for Alzheimer's disease (AD). Methods:A comprehensive search was carried out in three databases. The primary outcome was Mini-Mental...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,meta分析
doi:10.2147/CIA.S210062
更新日期:2019-07-12 00:00:00
abstract:Background:Aging leads to structural and functional changes in the vasculature characterized by arterial endothelial dysfunction and stiffening of large elastic arteries and is a predominant risk factor for cardiovascular disease, the leading cause of morbidity and mortality in modern societies. Although exercise reduc...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S220283
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND:Older patients with acute myocardial infarction (AMI) usually have a poor prognosis, but whether this poor prognosis leads to high hospital costs remains unclear. This study investigated the clinical outcomes of and costs incurred by older patients with AMI and metabolic syndrome (MS) in hospital. METHODS A...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S70372
更新日期:2015-01-23 00:00:00
abstract:BACKGROUND:Visual impairment is more prevalent in the elderly and depression is common in this population. Although many studies have investigated depression or quality of life (QOL) in older adults with visual impairment, few have looked at the association between these two concepts for this population. The aim of thi...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S27717
更新日期:2013-01-01 00:00:00
abstract:Objective:Urticaria is a mast cell-related disease caused severe itching and the lifetime prevalence of urticaria is about 20% in general population. Our purpose is to evaluate risk of urticaria in geriatric stroke patients received influenza vaccination (IV). Methods:In a cohort of 192,728 patients with newly diagnos...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S228324
更新日期:2019-11-26 00:00:00
abstract:Background and Aim:Caregivers in the home environment have an important role in timely detecting and responding to abuse. The aim of this review was to provide insight into both the existing tools for the assessment of and interventions for elder abuse by formal and informal caregivers in the home environment, and to c...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S261877
更新日期:2020-09-28 00:00:00
abstract::Uncertainty appears to typify the experience of living with dementia. With an uncertain illness trajectory and unpredictable levels of deterioration and stability in symptoms, people with a diagnosis of dementia may live with uncertainty and anxiety and find it hard to make plans or decisions for their future. People ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S70628
更新日期:2014-11-27 00:00:00