Abstract:
Purpose:Femoral neck fracture usually occurs in the geriatric population. Postoperative pneumonia (POP) is known to be devastated, and it is the most frequent complication among patients receiving surgical treatment for femoral neck fractures. However, whether patients who have hypoalbuminaemia are susceptible to the development of POP is a serious concern, although it has not been investigated. We attempted to investigate the association between newly developed POP and hypoalbuminaemia and to identify whether hypoalbuminaemia is an independent risk factor for POP after femoral neck fracture in geriatric population. Patients and methods:We retrospectively reviewed the records from the first 30 days after surgery of patients who were ≥65 years of age and who had a femoral neck fracture treated with surgery between January 2018 and December 2018 at the Honghui Hospital, Xi'an Jiaotong University. Patients were divided into two groups based on whether they did or did not experience POP, and their clinical characteristics were compared. Binomial logistic regression was used to identify potential risk factors of POP by analysing demographic factors, preoperative comorbidities, laboratory results, and surgical factors. Results:A total of 720 patients were included in the analysis, and 54 patients experienced POP. The incidence of POP after surgical treatment for a femoral neck fracture in this geriatric population was 7.5%. In addition, patients with POP had significantly longer hospital stays than patients without POP. The binary logistic regression analysis revealed that preoperative hypoalbuminaemia [odds ratio =5.187, 95% confidence interval (CI): 2.561-10.506, P<0.0001], COPD (OR =3.819, 95% CI: 1.247-11.701, P=0.019), prior stroke (OR =3.107, 95% CI: 1.470-6.568, P=0.003) and the time from injury to surgery (OR =1.076, 95% CI: 1.034-1.119, P<0.0001) were predominant and independent risk factors associated with POP after femoral neck fracture in this geriatric population. Conclusion:The current study revealed that among a geriatric population admitted for femoral neck fracture surgery, preoperative hypoalbuminaemia was a predictor of POP, followed by COPD, prior stroke and the time from injury to surgery. Thus, patients who undergo femoral neck fracture surgery and have preoperative hypoalbuminaemia should receive additional monitoring and perioperative care.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Wang Y,Li X,Ji Y,Tian H,Liang X,Li N,Wang Jdoi
10.2147/CIA.S231736subject
Has Abstractpub_date
2019-11-13 00:00:00pages
2007-2016eissn
1176-9092issn
1178-1998pii
231736journal_volume
14pub_type
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
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更新日期:2017-03-30 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
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更新日期:2014-08-16 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/cia.s9664
更新日期:2010-08-09 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S29045
更新日期:2012-01-01 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:Clinical interventions in aging
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journal_title:Clinical interventions in aging
pub_type: 杂志文章
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更新日期:2018-09-13 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-07-08 00:00:00
abstract::Fluctuating Parkinson's disease (PD) represents a clinical management challenge. The primary utility of levodopa in patients with PD is moderated by the "wearing off" phenomena seen with long-term use. COMT inhibitors slow down the rapid metabolism of levodopa, resulting in a more-sustained response to dopaminergic th...
journal_title:Clinical interventions in aging
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更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2020-06-26 00:00:00
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journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S77433
更新日期:2015-03-05 00:00:00