Oral anticoagulation to reduce risk of stroke in patients with atrial fibrillation: current and future therapies.

abstract：OBJECTIVE:The purpose of this work was to analyze and compare the movement kinematics of sit-to-stand (STS) and back-to-sit (BTS) transfers between frail aged adults and young subjects, as well as to determine the relationship between kinematic changes and functional capacities. METHODS:We analyzed the Timed Up and Go...

journal_title：Clinical interventions in aging

authors： Hassani A,Kubicki A,Brost V,Mourey F,Yang F

更新日期：2015-02-26 00:00:00

abstract：:After more than 40 years of clinical use, levodopa (LD) remains the gold standard of symptomatic efficacy in the drug treatment of Parkinson's disease (PD). Compared with other available dopaminergic therapies, dopamine replacement with LD is associated with the greatest improvement in motor function. Long-term treatm...

journal_title：Clinical interventions in aging

authors： Poewe W,Antonini A,Zijlmans JC,Burkhard PR,Vingerhoets F

更新日期：2010-09-07 00:00:00

abstract：:The evaluation of pain and the subsequent issue of pain control is a clinical challenge that all healthcare providers face. Pain in the elderly population is especially difficult given the myriad of physiological, pharmacological, and psychological aspects of caring for the geriatric patient. Opiates are the mainstay ...

journal_title：Clinical interventions in aging

authors： Chau DL,Walker V,Pai L,Cho LM

更新日期：2008-01-01 00:00:00

abstract：:Pharmacologic management of infections in elderly patients presents multiple challenges to health care professionals due to variable pharmacokinetics, pharmacodynamics, and immune function. Age is a well-established risk factor for infection, but furthermore is a risk factor for prolonged length of hospital stay, incr...

journal_title：Clinical interventions in aging

authors： Giarratano A,Green SE,Nicolau DP

更新日期：2018-04-17 00:00:00

abstract：PURPOSE:The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation. METHODS:Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or...

journal_title：Clinical interventions in aging

authors： Moschos MM,Chatziralli IP,Tsatsos M

更新日期：2015-08-24 00:00:00

abstract：Purpose:This study evaluates the effect of introducing active gait training (AGT) to patients who are severely disabled with nasogastric tube feeding or gastrostoma on the recovery of oral feeding. Patients and Methods:We conducted a historical cohort study at a single rehabilitation center in Japan between January 20...

journal_title：Clinical interventions in aging

authors： Arai H,Takeuchi J,Nozoe M,Fukuoka T,Matsumoto S,Morimoto T

更新日期：2020-10-13 00:00:00

abstract：:The percentage of the population described as elderly is growing, and a higher prevalence of multiple, chronic disease states must be managed concurrently. Healthcare practitioners must appropriately use medication for multiple diseases and avoid risks often associated with multiple medication use such as adverse effe...

journal_title：Clinical interventions in aging

authors： Bushardt RL,Massey EB,Simpson TW,Ariail JC,Simpson KN

更新日期：2008-01-01 00:00:00

abstract：:Endoscopic surgical treatment has become an option to treat benign prostate hyperplasia. We evaluated the safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients. We evaluated preoperative and perioperative parameters, functional outcomes, and adverse events up to 12 months postoperat...

journal_title：Clinical interventions in aging

authors： Shao IH,Hou CP,Chen SM,Chen CL,Lin YH,Chang PL,Tsui KH

更新日期：2013-01-01 00:00:00

abstract：Background:A thorough analysis of the capability for self-care in patients with heart failure (HF) reduces the frequency of hospitalizations that are caused by decompensation. The aim of the study was to assess the effect of the method of therapy for HF, the degree of the acceptance of illness, and the occurrence of fr...

journal_title：Clinical interventions in aging

authors： Mlynarska A,Golba KS,Mlynarski R

更新日期：2018-10-08 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) disproportionately affects older adults. However, direct comparison of clinical features, medical therapy, and outcomes in AF patients aged 65-74 and ≥ 75 years is rare. The objective of the present study was to evaluate the differences in clinical characteristics and prognosis in th...

journal_title：Clinical interventions in aging

authors： Shao XH,Yang YM,Zhu J,Zhang H,Liu Y,Gao X,Yu LT,Liu LS,Zhao L,Yu PF,Zhang H,He Q,Gu XD

更新日期：2014-08-12 00:00:00

abstract：BACKGROUND:It is important to obtain knowledge about the prevalence of nutritional risk and associated factors among older home-dwelling people in order to be able to meet nutritional challenges in this group in the future and to plan appropriate interventions. The aim of this survey was to investigate the prevalence o...

journal_title：Clinical interventions in aging

authors： Söderhamn U,Dale B,Sundsli K,Söderhamn O

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Despite advances in operative repair, ruptured abdominal aortic aneurysm (rAAA) remains associated with high mortality and morbidity rates, especially in elderly patients. The purpose of this study was to evaluate the outcomes of emergency endovascular aneurysm repair (eEVAR), conventional open repair (OPEN)...

journal_title：Clinical interventions in aging

authors： Raats JW,Flu HC,Ho GH,Veen EJ,Vos LD,Steyerberg EW,van der Laan L

更新日期：2014-10-13 00:00:00

abstract：:Taken once a year, intravenous zoledronic acid (Zol) (Reclast® or Aclasta®) is a third-generation nitrogen-containing bisphosphonate that is effective compared with placebo in reducing the risk of fractures in patients with postmenopausal osteoporosis and recent low-trauma hip fracture. In glucocorticoid-induced osteo...

journal_title：Clinical interventions in aging

authors： Räkel A,Boucher A,Ste-Marie LG

更新日期：2011-01-01 00:00:00

abstract：:Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...

journal_title：Clinical interventions in aging

authors： Kawate H,Takayanagi R

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To report our experiences in changing from intravitreal bevacizumab to ranibizumab in age-related macular degeneration (AMD). DESIGN:Retrospective case series. PARTICIPANTS AND METHODS:We retrospectively reviewed the records of 34 patients (36 eyes) who were treated with monthly injections of intravitreal b...

journal_title：Clinical interventions in aging

authors： Karagiannis DA,Ladas ID,Parikakis E,Georgalas I,Kotsolis A,Amariotakis G,Soumplis V,Mitropoulos P

更新日期：2009-01-01 00:00:00

abstract：Background:Aging leads to structural and functional changes in the vasculature characterized by arterial endothelial dysfunction and stiffening of large elastic arteries and is a predominant risk factor for cardiovascular disease, the leading cause of morbidity and mortality in modern societies. Although exercise reduc...

journal_title：Clinical interventions in aging

authors： Huang J,Zhang H,Tan X,Hu M,Shen B

更新日期：2019-09-02 00:00:00

abstract：Background:Physical exercise is associated with decreased cardiovascular disease (CVD) risk, but recent large-scale trials suggest that exercise alone is insufficient to reduce CVD events in high-risk older adults. Purpose:This pilot randomized clinical trial aimed to collect critical data on feasibility, safety, and ...

journal_title：Clinical interventions in aging

authors： Roberts LM,Jaeger BC,Baptista LC,Harper SA,Gardner AK,Jackson EA,Pekmezi D,Sandesara B,Manini TM,Anton SD,Buford TW

更新日期：2019-10-23 00:00:00

abstract：Background:Aging is a spontaneous and inevitable phenomenon of biology, which can lead to the gradual deterioration of tissues and organs. One of the age-related deterioration processes is immunosenescence, which leads to changes in the function of immune systems, including immune cells and associated cytokines. A prop...

journal_title：Clinical interventions in aging

authors： Li X,Gao J,Yu Z,Jiang W,Sun W,Yu C,Sun J,Wang C,Chen J,Jing S,Li H

更新日期：2020-01-29 00:00:00

abstract：Objective:The objective involved the analysis of the efficiency of the Program of Movement Recreation of Elderly People (PMREP) exercise program expressed in terms of the stabilography measures and coactivation of muscles in women in the age group of 60-70 years. The assumption that was assumed stems from theoretical i...

journal_title：Clinical interventions in aging

authors： Borysiuk Z,Konieczny M,Kręcisz K,Pakosz P,Królikowska B

更新日期：2018-09-12 00:00:00

abstract：:The objective of this article is to review the current and emerging treatments of CKD prior to dialysis in the elderly. Worldwide, there are increasing numbers of people who are aged over 65 years. In parallel, there are increasing numbers of elderly patients presenting with chronic kidney disease (CKD), particularly ...

journal_title：Clinical interventions in aging

authors： Fassett RG

更新日期：2014-01-15 00:00:00

abstract：Introduction:The clinical benefit of invasive therapy in elderly patients with acute coronary syndrome (ACS) remains unclear. Furthermore, the decision-making process to treat this growing patient group is also debatable. The purpose of this study was to assess the association between elderly ACS patients, the treatmen...

journal_title：Clinical interventions in aging

authors： Rittger H,Stadelmaier C,Kieschnick T,Büber D,Rank K,Vitali-Serdoz L,Bastian D,Waliszewski M

更新日期：2020-05-25 00:00:00

abstract：Background:Functional dependence (FD) and vitamin D deficiency are common conditions in older adults. However, little is known about the relationship between FD and serum vitamin D status in centenarians. The current study was designed to evaluate the prevalence of FD and examine its relationship with serum vitamin D s...

journal_title：Clinical interventions in aging

authors： Yao Y,Fu S,Shi Q,Zhang H,Zhu Q,Zhang F,Luan F,Zhao Y,He Y

更新日期：2018-10-17 00:00:00

abstract：PURPOSE:Postmenopausal osteoporosis causes bone fracture as well as pain, physical, psychological and socially adverse effects, which affects a patient's quality of life (QOL). The effect of alendronate on QOL was investigated compared with that of alfacalcidol in post-menopausal osteoporotic women. PATIENTS AND METHO...

journal_title：Clinical interventions in aging

authors： Kawate H,Ohnaka K,Adachi M,Kono S,Ikematsu H,Matsuo H,Higuchi K,Takayama T,Takayanagi R

更新日期：2010-04-26 00:00:00

abstract：Background:Multiple cranial dural arteriovenous fistulas (dAVFs) are considered to be an uncommon vascular condition. dAVFs usually manifest with vague symptoms, which are related to the site of occurrence of the lesion and present with complex angio-architectural features, which in turn can render treatment procedures...

journal_title：Clinical interventions in aging

authors： Al-Abdulwahhab AH,Al-Suhibani S,Al-Sharydah AM,Al-Jubran SA,Al-Thuneyyan MA

更新日期：2020-12-08 00:00:00

abstract：Introduction:Older adults with chronic disease are more vulnerable to abuse. Early and accurate detection of the elderly abuse phenomenon can help identify health-promoting solutions for the elderly, their family, and society. The purpose of this study was to design and evaluate the psychometric properties of a questio...

journal_title：Clinical interventions in aging

authors： Mahmoudian A,Torabi Chafjiri R,Alipour A,Shamsalinia A,Ghaffari F

更新日期：2018-04-04 00:00:00

abstract：:Adverse drug reaction (ADR) risk-prediction models for use in older adults have been developed, but it is not clear if they are suitable for use in clinical practice. This systematic review aimed to identify and investigate the quality of validated ADR risk-prediction models for use in older adults. Standard computeri...

journal_title：Clinical interventions in aging

authors： Stevenson JM,Williams JL,Burnham TG,Prevost AT,Schiff R,Erskine SD,Davies JG

更新日期：2014-09-19 00:00:00

abstract：:Overactive bladder (OAB) is a difficult condition to live with and is very costly to the community. OAB affects 16% of the adult population and rises with increasing age. We describe the necessary steps in evaluation and behavioral therapy prior to initiating medical therapy. There are several medications that have be...

journal_title：Clinical interventions in aging

authors： Chughtai B,Levin R,De E

更新日期：2008-01-01 00:00:00

abstract：Purpose:The study aimed to investigate the association between body composition and frailty in elder inpatients. Patients and Methods:This is a cross-sectional study including 656 elder inpatients (275 females and 381 males) aged ≥65 years, from department of geriatrics of Zhejiang Hospital between January 2018 and Ma...

journal_title：Clinical interventions in aging

authors： Xu L,Zhang J,Shen S,Hong X,Zeng X,Yang Y,Liu Z,Chen L,Chen X

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:Vascular dementia (VaD) is a challenging illness that affects the lives of older adults and caregivers. It is unclear how multiple vascular risk factor exposures (polyvascular disease) affect VaD. PURPOSE:To determine the relationship between multiple vascular risk exposures, as counted on an index in cases...

journal_title：Clinical interventions in aging

authors： Takahashi PY,Caldwell CR,Targonski PV

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Cognitive screening upon hospital admission can provide important information about the patient's ability to process information during the inpatient stay. The Clock-in-the-Box (CIB) is a rapidly administered cognitive screening measure which has been previously validated with cognitive screening and neuropsych...

journal_title：Clinical interventions in aging

authors： Jackson CE,Grande LJ,Doherty K,Archambault E,Kelly B,Driver JA,Milberg WP,McGlinchey R,Rudolph JL

更新日期：2016-11-22 00:00:00