Choice of antimuscarinic agents for overactive bladder in the older patient: focus on darifenacin.

abstract：OBJECTIVE:We studied the effect of sustained virologic response (SVR) after treatment with pegylated-interferon (PEG-IFN) plus ribavirin on the development of liver cirrhosis in elderly patients with chronic hepatitis C (CHC). PATIENTS AND METHODS:This retrospective study enrolled 145 elderly CHC patients (aged ≥65 ye...

journal_title：Clinical interventions in aging

authors： Tseng CW,Chang TT,Tzeng SJ,Hsieh YH,Hung TH,Huang HT,Wu SF,Tseng KC

更新日期：2016-03-17 00:00:00

abstract：:Hypernatremia in the geriatric population is a common disorder associated with significant morbidity and mortality. Older people are predisposed to developing hypernatremia because of age-related physiologic changes such as decreased thirst drive, impaired urinary concentrating ability, and reduced total body water. M...

journal_title：Clinical interventions in aging

authors： Shah MK,Workeneh B,Taffet GE

更新日期：2014-11-19 00:00:00

abstract：Background:The study aimed to investigate the potential association of trunk skeletal muscle mass (tSM) and phase angle measured by bioelectrical impedance analysis (BIA) with the chance of femoral neck fractures in very elderly people. Patients and Methods:This case-control study enrolled 78 femoral neck fracture pat...

journal_title：Clinical interventions in aging

authors： Chen J,Lu K,Chen H,Hu N,Chen J,Liang X,Qin J,Huang W

更新日期：2020-06-12 00:00:00

abstract：OBJECTIVE:To investigate the long-term effects of three antiarthritics, namely dexamethasone, celecoxib, and methotrexate on the histology and metabolism of intact bone tissue in rats. METHODS:Thirty-two 12-week-old healthy female Sprague Dawley rats were randomly allocated into four groups: 1) control (saline, daily)...

journal_title：Clinical interventions in aging

authors： Liu Y,Cui Y,Chen Y,Gao X,Su Y,Cui L

更新日期：2015-08-05 00:00:00

abstract：BACKGROUND:Endovascular option has been proposed for a very limited and selected number of Stanford type A aortic dissection (TAAD) patients. We have performed a computed tomography (CT)-based TAAD study to explore appropriate endograft configurations for the ascending aortic pathology. METHODS:TAAD patients treated w...

journal_title：Clinical interventions in aging

authors： Zhang Y,Tang H,Zhou J,Liu Z,Liu C,Qiao T,Zhou M

更新日期：2016-07-14 00:00:00

abstract：:Vitamin E has been proposed as a potential clinical intervention for Alzheimer's disease (AD) given the plausibility of its various biological functions in influencing the neurodegenerative processes associated with the condition. The tocopherol and tocotrienol isoforms of vitamin E have multiple properties including ...

journal_title：Clinical interventions in aging

authors： Browne D,McGuinness B,Woodside JV,McKay GJ

更新日期：2019-07-18 00:00:00

abstract：OBJECTIVE:To estimate the value of the different thromboelastogram indices for predicting hemorrhage and vascular obstruction in an elderly population. METHODS:This was a prospective cohort study of patients 65 years and older without hemato-logic disorders who received thromboelastography (TEG) examination at the Chi...

journal_title：Clinical interventions in aging

authors： Zheng Q,Fu S,Chen D,Li X,Li Y,Li Y,Yu J,Gong M,Bai J

更新日期：2013-01-01 00:00:00

abstract：Objective:The number of long-term care (LTC) users and the associated expenditures in Japan are increasing dramatically. The national government recommends LTC prevention through activation of communities. However, there is no clear evidence of the effect of population-based comprehensive geriatric intervention program...

journal_title：Clinical interventions in aging

authors： Watanabe Y,Yamada Y,Yokoyama K,Yoshida T,Yoshinaka Y,Yoshimoto M,Tanaka Y,Itoi A,Yamagata E,Ebine N,Ishikawa-Takata K,Kimura M

更新日期：2018-05-24 00:00:00

abstract：:Nutrition is an important element of health in the older population and affects the aging process. The prevalence of malnutrition is increasing in this population and is associated with a decline in: functional status, impaired muscle function, decreased bone mass, immune dysfunction, anemia, reduced cognitive functio...

journal_title：Clinical interventions in aging

authors： Ahmed T,Haboubi N

更新日期：2010-08-09 00:00:00

abstract：OBJECTIVE:The aim of this case series was to assess the impact of auditory rehabilitation with cochlear implantation on the cognitive function of elderly patients over time. DESIGN:This is a longitudinal case series of prospective data assessing neurocognitive function and speech perception in an elderly cohort pre- a...

journal_title：Clinical interventions in aging

authors： Cosetti MK,Pinkston JB,Flores JM,Friedmann DR,Jones CB,Roland JT Jr,Waltzman SB

更新日期：2016-05-12 00:00:00

abstract：BACKGROUND:Research on crisis teams for older adults with dementia is limited. This scoping review aimed to 1) conduct a systematic literature review reporting on the effectiveness of crisis interventions for older people with dementia and 2) conduct a scoping survey with dementia crisis teams mapping services across E...

journal_title：Clinical interventions in aging

authors： Streater A,Coleston-Shields DM,Yates J,Stanyon M,Orrell M

更新日期：2017-10-03 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is closely linked to cardiovascular risk factors. METHODS:Echocardiographic studies were performed, including left ventricular diastolic functions, left and right atrial conduction times, and arterial stiffness parameters, namely stiffness index, pressure-strain elastic modulus, and...

journal_title：Clinical interventions in aging

authors： Çalık AN,Özcan KS,Yüksel G,Güngör B,Aruğarslan E,Varlibas F,Ekmekci A,Osmonov D,Tatlısu MA,Karaca M,Bolca O,Erdinler İ

更新日期：2014-07-16 00:00:00

abstract：BACKGROUND:Digoxin is a frequently prescribed drug, particularly in the elderly population, in which there is an increased prevalence of atrial fibrillation and cardiac failure. With its complex pharmacokinetic profile and narrow therapeutic index, use of digoxin requires regular monitoring of blood levels. Recent evid...

journal_title：Clinical interventions in aging

authors： Zhao L,Yang P,Li P,Wang X,Qin W,Zhang X

更新日期：2014-07-22 00:00:00

abstract：Purpose:This study aimed to investigate the effect of religious intervention on depressive symptoms and quality of life (QOL) among Indonesian elderly in nursing homes (NHs). Patients and methods:This was a quasi-experimental study with repeated measures. Sixty elderly residents at three NHs in three districts in Yogy...

journal_title：Clinical interventions in aging

authors： Pramesona BA,Taneepanichskul S

更新日期：2018-03-23 00:00:00

abstract：:Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups disproportionately affected. Treatment of older people with diabetes differs in many ways from that in younger adults since the majority have type 2 disease and are at particular risk of macrovascular rather t...

journal_title：Clinical interventions in aging

authors： Marouf E,Sinclair AJ

更新日期：2009-01-01 00:00:00

abstract：:Fluctuating Parkinson's disease (PD) represents a clinical management challenge. The primary utility of levodopa in patients with PD is moderated by the "wearing off" phenomena seen with long-term use. COMT inhibitors slow down the rapid metabolism of levodopa, resulting in a more-sustained response to dopaminergic th...

journal_title：Clinical interventions in aging

authors： Stocchi F,De Pandis MF

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:The main purpose of this study was to investigate whether carotid artery stenting (CAS) plus medicine in patients with severe carotid artery stenosis provide a better long-term blood pressure (BP) control compared to other medical treatments alone. The other aim was to explore the correlation between post-CA...

journal_title：Clinical interventions in aging

authors： Chang A,Hung HF,Hsieh FI,Chen WH,Yeh HL,Yeh JH,Chiu HC,Lien LM

更新日期：2017-01-06 00:00:00

abstract：:Lumbar kyphosis and the decreased mobility of the lumbar spine increase the risk of falls and impair both the quality of life and the ability to perform activities of daily living. However, in the elderly Japanese population, little is known about the age-related changes and sex-related differences in muscle strength,...

journal_title：Clinical interventions in aging

authors： Kasukawa Y,Miyakoshi N,Hongo M,Ishikawa Y,Kudo D,Suzuki M,Mizutani T,Kimura R,Ono Y,Shimada Y

更新日期：2017-02-20 00:00:00

abstract：OBJECTIVE:Routine measurement of the carotid intima-media thickness is not recommended in recent clinical practice guidelines for risk assessment of the first atherosclerotic cardiovascular disease (ASCVD) event (the definition of which includes acute coronary syndromes, a history of myocardial infarction, stable or un...

journal_title：Clinical interventions in aging

authors： Kim G,Youn HJ,Choi YS,Jung HO,Chung WS,Kim CM

更新日期：2015-07-07 00:00:00

abstract：:Osteoporosis and fragility fractures are relevant health issues because of their impact in terms of morbidity, mortality, and socioeconomic burden. Despite this alarming scenario, both underdiagnosis and undertreatment are common features of osteoporotic patients, particularly those who have already sustained a fragil...

journal_title：Clinical interventions in aging

authors： Iolascon G,Moretti A,Toro G,Gimigliano F,Liguori S,Paoletta M

更新日期：2020-03-26 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most common arrhythmia in patients with chronic kidney disease (CKD), and the combined prevalence of these two disorders increases as the population ages. Both AF and CKD have risk factors for development of each other and eventual mortality. However, the relationship between ...

journal_title：Clinical interventions in aging

authors： Fu S,Liu T,Luo L,Ye P

更新日期：2014-02-14 00:00:00

abstract：PURPOSE:Postmenopausal osteoporosis causes bone fracture as well as pain, physical, psychological and socially adverse effects, which affects a patient's quality of life (QOL). The effect of alendronate on QOL was investigated compared with that of alfacalcidol in post-menopausal osteoporotic women. PATIENTS AND METHO...

journal_title：Clinical interventions in aging

authors： Kawate H,Ohnaka K,Adachi M,Kono S,Ikematsu H,Matsuo H,Higuchi K,Takayama T,Takayanagi R

更新日期：2010-04-26 00:00:00

abstract：:Fracture of the hip is frequently a catastrophic event in the elderly, often resulting in death within a year and of the survivors, few regain pre-fracture quality of life. Although less appreciated, fractures of the spine result in significant morbidity and are also associated with increased mortality compared with i...

journal_title：Clinical interventions in aging

authors： Bodenner D,Redman C,Riggs A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Gerontological research aims at understanding factors that are crucial for mediating "successful aging". This term denotes the absence of significant disease and disabilities, maintenance of high levels of physical and cognitive function, and preservation of social and productive activities. Preservation of ...

journal_title：Clinical interventions in aging

authors： Kalisch T,Richter J,Lenz M,Kattenstroth JC,Kolankowska I,Tegenthoff M,Dinse HR

更新日期：2011-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is associated with an increased incidence and severity of strokes. The burden of AF-related stroke is expected to increase in parallel with the aging of the population. Oral anticoagulation with warfarin has been the pharmacologic standard for stroke risk reduction in patients with AF. When us...

journal_title：Clinical interventions in aging

authors： Amin A

更新日期：2013-01-01 00:00:00

abstract：:Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due...

journal_title：Clinical interventions in aging

authors： Ughi N,Crotti C,Ingegnoli F

更新日期：2016-03-14 00:00:00

abstract：Objective:We studied the efficacy of zoledronic acid (ZOL) infusion on radiographic and clinical outcomes after percutaneous kyphoplasty (PKP) for elderly patients with osteoporotic thoracolumbar fractures (osteoporotic vertebral compression fractures [OVCFs]). Materials and methods:We retrospectively analyzed 95 elde...

journal_title：Clinical interventions in aging

authors： Shi C,Zhang M,Cheng AY,Huang ZF

更新日期：2018-05-04 00:00:00

abstract：Background:Multiple cranial dural arteriovenous fistulas (dAVFs) are considered to be an uncommon vascular condition. dAVFs usually manifest with vague symptoms, which are related to the site of occurrence of the lesion and present with complex angio-architectural features, which in turn can render treatment procedures...

journal_title：Clinical interventions in aging

authors： Al-Abdulwahhab AH,Al-Suhibani S,Al-Sharydah AM,Al-Jubran SA,Al-Thuneyyan MA

更新日期：2020-12-08 00:00:00

abstract：:Taken once a year, intravenous zoledronic acid (Zol) (Reclast® or Aclasta®) is a third-generation nitrogen-containing bisphosphonate that is effective compared with placebo in reducing the risk of fractures in patients with postmenopausal osteoporosis and recent low-trauma hip fracture. In glucocorticoid-induced osteo...

journal_title：Clinical interventions in aging

authors： Räkel A,Boucher A,Ste-Marie LG

更新日期：2011-01-01 00:00:00

abstract：Background:Myocardial infarction (MI) is a common cause of death worldwide. It is characterized by coronary artery occlusion that causes ischemia and hypoxia of myocardial cells, leading to irreversible myocardial damage. Materials and Methods:To explore potential targets for treatment of MI, we reorganized and analyz...

journal_title：Clinical interventions in aging

authors： Yu YW,Xue YJ,Qian LL,Chen Z,Que JQ,Huang KY,Liu S,Weng YB,Rong FN,Ji KT,Zeng JN

更新日期：2020-12-01 00:00:00