Effects of dexamethasone, celecoxib, and methotrexate on the histology and metabolism of bone tissue in healthy Sprague Dawley rats.

abstract：OBJECTIVE:We studied the effect of sustained virologic response (SVR) after treatment with pegylated-interferon (PEG-IFN) plus ribavirin on the development of liver cirrhosis in elderly patients with chronic hepatitis C (CHC). PATIENTS AND METHODS:This retrospective study enrolled 145 elderly CHC patients (aged ≥65 ye...

journal_title：Clinical interventions in aging

authors： Tseng CW,Chang TT,Tzeng SJ,Hsieh YH,Hung TH,Huang HT,Wu SF,Tseng KC

更新日期：2016-03-17 00:00:00

abstract：Background:Care transitions programs are increasingly used to improve care and reduce re-admission of patients after hospitalization. To learn from the experience of patients who have participated in the Mayo Clinic Care Transitions (MCCT) program and to understand the patient experience, we sought perspectives of pati...

journal_title：Clinical interventions in aging

authors： Takahashi PY,Finnie DM,Quigg SM,Borkenhagen LS,Kumbamu A,Kimeu AK,Griffin JM

更新日期：2018-12-19 00:00:00

abstract：:Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...

journal_title：Clinical interventions in aging

authors： Kawate H,Takayanagi R

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Laminectomy/laminotomy and foraminotomy are well established surgical techniques for treatment of symptomatic lumbar spinal stenosis. However, these procedures have significant limitations, including limited access to lateral and foraminal compression and postoperative instability. The purpose of this cadave...

journal_title：Clinical interventions in aging

authors： Lauryssen C,Berven S,Mimran R,Summa C,Sheinberg M,Miller LE,Block JE

更新日期：2012-01-01 00:00:00

abstract：Purpose:This study aimed to investigate the effect of religious intervention on depressive symptoms and quality of life (QOL) among Indonesian elderly in nursing homes (NHs). Patients and methods:This was a quasi-experimental study with repeated measures. Sixty elderly residents at three NHs in three districts in Yogy...

journal_title：Clinical interventions in aging

authors： Pramesona BA,Taneepanichskul S

更新日期：2018-03-23 00:00:00

abstract：:Numerous randomized, double-blind, placebo-controlled studies and observational studies have demonstrated that statins decrease mortality and major cardiovascular events in older high-risk persons with hypercholesterolemia. The Heart Protection Study found that statins decreased mortality and major cardiovascular even...

journal_title：Clinical interventions in aging

authors： Aronow WS

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:It is important to obtain knowledge about the prevalence of nutritional risk and associated factors among older home-dwelling people in order to be able to meet nutritional challenges in this group in the future and to plan appropriate interventions. The aim of this survey was to investigate the prevalence o...

journal_title：Clinical interventions in aging

authors： Söderhamn U,Dale B,Sundsli K,Söderhamn O

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this work was to analyze and compare the movement kinematics of sit-to-stand (STS) and back-to-sit (BTS) transfers between frail aged adults and young subjects, as well as to determine the relationship between kinematic changes and functional capacities. METHODS:We analyzed the Timed Up and Go...

journal_title：Clinical interventions in aging

authors： Hassani A,Kubicki A,Brost V,Mourey F,Yang F

更新日期：2015-02-26 00:00:00

abstract：PURPOSE:Cardiovascular diseases are the leading cause of death and disability worldwide. Among these diseases, heart failure (HF) and acute myocardial infarction (AMI) are the most common causes of hospitalization. Therefore, readmission for HF and AMI is receiving increasing attention. Several socioeconomic factors co...

journal_title：Clinical interventions in aging

authors： Damiani G,Salvatori E,Silvestrini G,Ivanova I,Bojovic L,Iodice L,Ricciardi W

更新日期：2015-01-12 00:00:00

abstract：:The topic of motor vehicle crashes among the elderly is dynamic and multi-faceted requiring a comprehensive and synergistic approach to intervention planning. This approach must be based on the values of a given population as well as health statistics and asserted through community, organizational and policy strategie...

journal_title：Clinical interventions in aging

authors： Classen S,Lopez ED,Winter S,Awadzi KD,Ferree N,Garvan CW

更新日期：2007-01-01 00:00:00

abstract：Purpose:Producing tongue pressure (TP) by pushing the tongue against the palate consists of lifting the tongue muscles and elevating the floor of the mouth via suprahyoid muscle contraction. Though studies have shown that tongue-pressure resistance training (TPRT) increases tongue function, none have focused on suprahy...

journal_title：Clinical interventions in aging

authors： Namiki C,Hara K,Tohara H,Kobayashi K,Chantaramanee A,Nakagawa K,Saitou T,Yamaguchi K,Yoshimi K,Nakane A,Minakuchi S

更新日期：2019-03-22 00:00:00

abstract：Purpose:Define the effectiveness of teriparatide (TPTD) treatment on reducing the incidence of new vertebral compression fractures (NVCFs) and back pain and improving quality of life after percutaneous kyphoplasty (PKP). Methods:Two years of clinical follow-up data from primary osteoporotic women who had experienced i...

journal_title：Clinical interventions in aging

authors： Kong M,Zhou C,Zhu K,Zhang Y,Song M,Zhang H,Tu Q,Ma X

更新日期：2019-10-01 00:00:00

abstract：:Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes. Two major frailty models have been described in the literature. The frailty phenotype defines frai...

journal_title：Clinical interventions in aging

authors： Chen X,Mao G,Leng SX

更新日期：2014-03-19 00:00:00

abstract：Background:Myocardial infarction (MI) is a common cause of death worldwide. It is characterized by coronary artery occlusion that causes ischemia and hypoxia of myocardial cells, leading to irreversible myocardial damage. Materials and Methods:To explore potential targets for treatment of MI, we reorganized and analyz...

journal_title：Clinical interventions in aging

authors： Yu YW,Xue YJ,Qian LL,Chen Z,Que JQ,Huang KY,Liu S,Weng YB,Rong FN,Ji KT,Zeng JN

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Early-stage chronic kidney disease has been suggested to be correlated with cognitive decline, but the association has rarely been explored in the oldest old. SUBJECTS AND METHODS:This prospective study included 284 Chinese participants aged 80 years or older with serum creatinine levels <150 µmol/L. The me...

journal_title：Clinical interventions in aging

authors： Bai K,Pan Y,Lu F,Zhao Y,Wang J,Zhang L

更新日期：2017-07-04 00:00:00

abstract：Background:Depression in the elderly is a serious and often underdiagnosed psychiatric disorder that has been linked to adverse outcomes in the hospital setting. This study aims to evaluate the prevalence of depressive symptoms and associated factors among elderly hospital inpatients. Methods:The cross-sectional study...

journal_title：Clinical interventions in aging

authors： Zou C,Chen S,Shen J,Zheng X,Wang L,Guan L,Liu Q,Yang Y

更新日期：2018-09-13 00:00:00

abstract：:Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups disproportionately affected. Treatment of older people with diabetes differs in many ways from that in younger adults since the majority have type 2 disease and are at particular risk of macrovascular rather t...

journal_title：Clinical interventions in aging

authors： Marouf E,Sinclair AJ

更新日期：2009-01-01 00:00:00

abstract：Background:When considering the "joint as an organ", the tissues in a joint act as complementary components of an organ, and the "set point" is the cellular activity for homeostasis of the joint tissues. Even in the absence of injury, joint tissues have adaptive responses to processes, like aging and menopause, which r...

journal_title：Clinical interventions in aging

authors： Rollick NC,Lemmex DB,Ono Y,Reno CR,Hart DA,Lo IK,Thornton GM

更新日期：2018-03-01 00:00:00

abstract：:Osteoporosis is a condition causing significant morbidity and mortality in the elderly population worldwide. Age-related testosterone deficiency is the most important factor of bone loss in elderly men. Androgen can influence bone health by binding to androgen receptors directly or to estrogen receptors (ERs) indirect...

journal_title：Clinical interventions in aging

authors： Mohamad NV,Soelaiman IN,Chin KY

更新日期：2016-09-22 00:00:00

abstract：OBJECTIVE:The best practice tariff (BPT) incentivizes hospitals in the England and Wales National Health Service to provide multiprofessional care to patients with hip fractures. The initial six targets included: 1) admission under consultant-led joint orthopedic-geriatric care, 2) multidisciplinary assessment protocol...

journal_title：Clinical interventions in aging

authors： Khan SK,Shirley MD,Glennie C,Fearon PV,Deehan DJ

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Endovascular option has been proposed for a very limited and selected number of Stanford type A aortic dissection (TAAD) patients. We have performed a computed tomography (CT)-based TAAD study to explore appropriate endograft configurations for the ascending aortic pathology. METHODS:TAAD patients treated w...

journal_title：Clinical interventions in aging

authors： Zhang Y,Tang H,Zhou J,Liu Z,Liu C,Qiao T,Zhou M

更新日期：2016-07-14 00:00:00

abstract：BACKGROUND:No conventional creatinine- or cystatin C-based glomerular filtration rate (GFR) estimation equation performed consistently outstandingly in elderly Chinese in our previous studies. This research aimed to further evaluate the performance of some recently proposed estimation equations based on creatinine and ...

journal_title：Clinical interventions in aging

authors： Ye X,Wei L,Pei X,Zhu B,Wu J,Zhao W

更新日期：2014-09-11 00:00:00

abstract：Background:Transcutaneous electrical nerve stimulation (TENS) is a noninvasive modality which may be used to reduce acute postoperative pain. Intense perioperative pain within the first few days after hip fracture surgery is common and is related to negative consequences such as restricted and delayed ambulation. Obje...

journal_title：Clinical interventions in aging

authors： Elboim-Gabyzon M,Andrawus Najjar S,Shtarker H

更新日期：2019-10-29 00:00:00

abstract：PURPOSE:Osteoarthritis (OA) is a degenerative disease characterized by a progressive loss of articular cartilage extracellular matrix and is due to functional impairments occurring in chondrocytes. In previous works, we highlighted that Regenerative Tissue Optimization (TO-RGN) treatment with radioelectric asymmetric c...

journal_title：Clinical interventions in aging

authors： Collodel G,Fioravanti A,Pascarelli NA,Lamboglia A,Fontani V,Maioli M,Santaniello S,Pigliaru G,Castagna A,Moretti E,Iacoponi F,Rinaldi S,Ventura C

更新日期：2013-01-01 00:00:00

abstract：:Background and objective: Oxidative stress has been demonstrated to be a mechanism that leads to bone mass reduction, and according to many studies, serum uric acid (UA) is a strong endogenous antioxidant that can protect bone mineral density (BMD). To date, there have been no large-scale, cross-sectional studies base...

journal_title：Clinical interventions in aging

authors： Chen F,Wang Y,Guo Y,Wang J,Yang A,Lv Q,Liu Y,Ma G,Liu Y,Wang D

更新日期：2019-06-12 00:00:00

abstract：Objective:We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy of cognitive stimulation therapy (CST) of different durations for Alzheimer's disease (AD). Methods:A comprehensive search was carried out in three databases. The primary outcome was Mini-Mental...

journal_title：Clinical interventions in aging

authors： Chen J,Duan Y,Li H,Lu L,Liu J,Tang C

更新日期：2019-07-12 00:00:00

abstract：OBJECTIVE:This cross-sectional study compared three tools for predicting painful new osteoporotic vertebral fractures (PNOVFs) in older Chinese men: bone mineral density (BMD), the Osteoporosis Self-Assessment Tool for Asians (OSTA), and the World Health Organization fracture risk assessment tool (FRAX) (without BMD). ...

journal_title：Clinical interventions in aging

authors： Lin J,Yang Y,Fei Q,Zhang X,Ma Z,Wang Q,Li J,Li D,Meng Q,Wang B

更新日期：2016-04-22 00:00:00

abstract：Background:Aging leads to structural and functional changes in the vasculature characterized by arterial endothelial dysfunction and stiffening of large elastic arteries and is a predominant risk factor for cardiovascular disease, the leading cause of morbidity and mortality in modern societies. Although exercise reduc...

journal_title：Clinical interventions in aging

authors： Huang J,Zhang H,Tan X,Hu M,Shen B

更新日期：2019-09-02 00:00:00

abstract：:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely assoc...

journal_title：Clinical interventions in aging

authors： Manzon L,Ettorre E,Viscogliosi G,Ippoliti S,Filiaci F,Ungari C,Fratto G,Agrillo A

更新日期：2014-08-25 00:00:00

abstract：:Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due...

journal_title：Clinical interventions in aging

authors： Ughi N,Crotti C,Ingegnoli F

更新日期：2016-03-14 00:00:00