Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report.

Abstract:

:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely associated with BRONJ. Instead, the risk greatly increases whether the patient is concomitantly taking steroid and/or immunosuppressant agents. The aims of this paper are to briefly discuss the evidence of the associations between bisphosphonate therapy and BRONJ, and the effects of co-occurring factors such as the presence of rheumatoid arthritis, dental surgery, and concomitant corticosteroid therapy. In particular, we present the case of an elderly woman with BRONJ suffering from rheumatoid arthritis, with a recent dental extraction and with a very unusual complication: a temporal abscess, who was successfully treated.

journal_name

Clin Interv Aging

authors

Manzon L,Ettorre E,Viscogliosi G,Ippoliti S,Filiaci F,Ungari C,Fratto G,Agrillo A

doi

10.2147/CIA.S67726

subject

Has Abstract

pub_date

2014-08-25 00:00:00

pages

1409-13

eissn

1176-9092

issn

1178-1998

pii

cia-9-1409

journal_volume

9

pub_type

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