Abstract:
:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely associated with BRONJ. Instead, the risk greatly increases whether the patient is concomitantly taking steroid and/or immunosuppressant agents. The aims of this paper are to briefly discuss the evidence of the associations between bisphosphonate therapy and BRONJ, and the effects of co-occurring factors such as the presence of rheumatoid arthritis, dental surgery, and concomitant corticosteroid therapy. In particular, we present the case of an elderly woman with BRONJ suffering from rheumatoid arthritis, with a recent dental extraction and with a very unusual complication: a temporal abscess, who was successfully treated.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Manzon L,Ettorre E,Viscogliosi G,Ippoliti S,Filiaci F,Ungari C,Fratto G,Agrillo Adoi
10.2147/CIA.S67726subject
Has Abstractpub_date
2014-08-25 00:00:00pages
1409-13eissn
1176-9092issn
1178-1998pii
cia-9-1409journal_volume
9pub_type
杂志文章abstract:Objective:The aim of this study was to evaluate the effects of dental status and chewing efficiency on the oral-health-related quality of life (OHRQoL) of nursing-home residents. Materials and Methods:The study was conducted in nine nursing homes. All eligible participants were included, and general and medical data, ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S273671
更新日期:2020-11-11 00:00:00
abstract:BACKGROUND:The skeletal muscle echo intensity (EI) during ultrasound imaging has been investigated to evaluate the muscle quality. However, EI fluctuates according to the scanning conditions. METHODS:The motor functions and ultrasound images of 19 elderly (73 ± 3.2 years) and 19 young (22 ± 1.5 years) individuals were...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S67820
更新日期:2014-09-05 00:00:00
abstract::Pharmacologic management of infections in elderly patients presents multiple challenges to health care professionals due to variable pharmacokinetics, pharmacodynamics, and immune function. Age is a well-established risk factor for infection, but furthermore is a risk factor for prolonged length of hospital stay, incr...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S133640
更新日期:2018-04-17 00:00:00
abstract::Fluctuating Parkinson's disease (PD) represents a clinical management challenge. The primary utility of levodopa in patients with PD is moderated by the "wearing off" phenomena seen with long-term use. COMT inhibitors slow down the rapid metabolism of levodopa, resulting in a more-sustained response to dopaminergic th...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/ciia.2006.1.4.317
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:One of the key clinical features of Alzheimer's disease (AD) is impairment in daily functioning. Patients with mild cognitive impairment (MCI) also commonly have mild problems performing complex tasks. Information and communication technology (ICT), particularly techniques involving imaging and video process...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S36297
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Life style and physical activity play a pivotal role in prevention and treatment of osteoporosis. The mechanism for better bone metabolism and improvement of physical disorders is not clear yet. Trace minerals such as Ca, Mn, Cu, and Zn are essential precursors for most vital biological process, especially t...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S100566
更新日期:2016-02-29 00:00:00
abstract::Age remains the most powerful prognostic factor among glioblastoma (GBM) patients. Half of all patients with GBM are aged 65 years or older at the time of diagnosis, and the incidence rate of GBM in patients aged over 65 years is increasing rapidly. Median survival for elderly GBM patients is less than 6 months and re...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S44259
更新日期:2014-02-21 00:00:00
abstract::The objective of this article is to review the current and emerging treatments of CKD prior to dialysis in the elderly. Worldwide, there are increasing numbers of people who are aged over 65 years. In parallel, there are increasing numbers of elderly patients presenting with chronic kidney disease (CKD), particularly ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S39763
更新日期:2014-01-15 00:00:00
abstract::Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient's functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S102577
更新日期:2016-03-14 00:00:00
abstract:PURPOSE:To assess the relative role of handgrip strength (HGS), quadriceps muscle power (Pmax), and optimal shortening velocity (υopt) in maintaining functional abilities (FAs) in older adults living in a long-term care home over a 1-year follow-up. SUBJECTS AND METHODS:Forty-one inactive older institutionalized adult...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S101043
更新日期:2016-05-26 00:00:00
abstract:PURPOSE:Patients leaving the hospital are at increased risk of functional decline and hospital readmission. The Employee and Community Health service at Mayo Clinic in Rochester developed a care transition program (CTP) to provide home-based care services for medically complex patients. The study objective was to deter...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S44390
更新日期:2013-01-01 00:00:00
abstract:Background:Being elderly and retired are related phenomena that overlap in a time symmetry. The present study aimed to assess the effect of an empowering self-management model on the self-efficacy and sense of coherence (SOC) in retired elderly with chronic diseases. Methods:A randomized controlled trial that included...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S183276
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To study the feasibility of first, reaching functionally declined, but still independent older persons at risk of falls through their general practitioner (GP) and second, to reduce their physiological and psychological fall risk factors with a complex exercise intervention. We investigated the effects of a 16-...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S46218
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Postvertebral augmentation vertebral compression fractures are common; repeated vertebral augmentation is usually performed for prompt pain relief. This study aimed to evaluate the incidence and risk factors of repeat vertebral augmentation. METHODS:We performed a retrospective, nationwide, population-based lo...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S80668
更新日期:2015-03-27 00:00:00
abstract:Purpose:Define the effectiveness of teriparatide (TPTD) treatment on reducing the incidence of new vertebral compression fractures (NVCFs) and back pain and improving quality of life after percutaneous kyphoplasty (PKP). Methods:Two years of clinical follow-up data from primary osteoporotic women who had experienced i...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S224663
更新日期:2019-10-01 00:00:00
abstract:Purpose:Sleep disorders, such as insomnia with objective short sleep duration, are associated with increased risk of hypertension. The objective of the study was to evaluate the effects of insomnia and daytime sleepiness on the quality of life (QOL) among elderly hypertensive patients. Patients and methods:This cross-...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S188499
更新日期:2019-01-15 00:00:00
abstract::Heart failure is a common and disabling condition with morbidity and mortality that increase dramatically with advancing age. Large observational studies, retrospective subgroup analyses and meta-analyses of clinical trials in systolic heart failure, and recently published randomized studies have provided data support...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S4482
更新日期:2010-12-03 00:00:00
abstract:OBJECTIVE:We studied the effect of sustained virologic response (SVR) after treatment with pegylated-interferon (PEG-IFN) plus ribavirin on the development of liver cirrhosis in elderly patients with chronic hepatitis C (CHC). PATIENTS AND METHODS:This retrospective study enrolled 145 elderly CHC patients (aged ≥65 ye...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S97242
更新日期:2016-03-17 00:00:00
abstract::Avoiding medications in which the risks outweigh the benefits in the elderly patient is a challenge for physicians, and different criteria to identify inappropriate prescription (IP) exist to aid prescribers. Definition of IP indicators in the Italian geriatric population affected by cardiovascular disease and chronic...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S137403
更新日期:2017-10-19 00:00:00
abstract:BACKGROUND:Delirium in hip fractured patients is a frequent complication. Dementia is an important risk factor for delirium and is common in frail elderly. This study aimed to extend the previous knowledge on risk factors for delirium and the consequences. Special attention was given to patients with dementia and delir...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S115945
更新日期:2017-03-10 00:00:00
abstract:Background:Neuromuscular electrical stimulation with muscle contraction, administered through the skin of the neck, improves a patient's swallowing ability. However, the beneficial effects of transcutaneous electrical sensory stimulation (TESS), without muscle contraction, are controversial. We investigated the effect ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S140746
更新日期:2017-11-07 00:00:00
abstract:Study design:Multivariate analysis of retrospective registry data. Objective:To report the perioperative complication in a large cohort of surgery for elderly degenerative lumbar scoliosis (DLS) patients and to analyze the risk factors. Summary of background data:The perioperative complication rate and risk factors f...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S218204
更新日期:2019-12-16 00:00:00
abstract:Background:Functional dependence (FD) and vitamin D deficiency are common conditions in older adults. However, little is known about the relationship between FD and serum vitamin D status in centenarians. The current study was designed to evaluate the prevalence of FD and examine its relationship with serum vitamin D s...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S182318
更新日期:2018-10-17 00:00:00
abstract::Hypernatremia in the geriatric population is a common disorder associated with significant morbidity and mortality. Older people are predisposed to developing hypernatremia because of age-related physiologic changes such as decreased thirst drive, impaired urinary concentrating ability, and reduced total body water. M...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S65214
更新日期:2014-11-19 00:00:00
abstract::Fracture of the hip is frequently a catastrophic event in the elderly, often resulting in death within a year and of the survivors, few regain pre-fracture quality of life. Although less appreciated, fractures of the spine result in significant morbidity and are also associated with increased mortality compared with i...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/cia.s241
更新日期:2007-01-01 00:00:00
abstract::Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes. Two major frailty models have been described in the literature. The frailty phenotype defines frai...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S45300
更新日期:2014-03-19 00:00:00
abstract:OBJECTIVE:This cross-sectional study compared three tools for predicting painful new osteoporotic vertebral fractures (PNOVFs) in older Chinese men: bone mineral density (BMD), the Osteoporosis Self-Assessment Tool for Asians (OSTA), and the World Health Organization fracture risk assessment tool (FRAX) (without BMD). ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S101078
更新日期:2016-04-22 00:00:00
abstract::Numerous randomized, double-blind, placebo-controlled studies and observational studies have demonstrated that statins decrease mortality and major cardiovascular events in older high-risk persons with hypercholesterolemia. The Heart Protection Study found that statins decreased mortality and major cardiovascular even...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/ciia.2006.1.4.433
更新日期:2006-01-01 00:00:00
abstract:Purpose:This study evaluates the effect of introducing active gait training (AGT) to patients who are severely disabled with nasogastric tube feeding or gastrostoma on the recovery of oral feeding. Patients and Methods:We conducted a historical cohort study at a single rehabilitation center in Japan between January 20...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S270277
更新日期:2020-10-13 00:00:00
abstract:BACKGROUND:No conventional creatinine- or cystatin C-based glomerular filtration rate (GFR) estimation equation performed consistently outstandingly in elderly Chinese in our previous studies. This research aimed to further evaluate the performance of some recently proposed estimation equations based on creatinine and ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S68801
更新日期:2014-09-11 00:00:00