Abstract:
PURPOSE:The effects of a multicomponent dyadic intervention on the mood, behavior, and physical health of people with dementia living in the community were evaluated in a randomized controlled trial. This multicomponent dyadic intervention is a translated and adapted version of an intervention that has been shown to be effective for people with dementia in the US. PATIENTS AND METHODS:People with dementia living in the community and their family caregivers (N=111 caregiver-care recipient dyads) were randomly assigned to the intervention and comparison group. The intervention group received home-based physical exercise training, psycho-education, communication skills training, and pleasant activities training during 3 months directed at both the person with dementia and the caregiver. Mood, behavior, and physical health were measured at baseline, 3 months, and 6 months. The effects of the study were determined by using generalized estimating equations based on an intention-to-treat analysis. RESULTS:Analyses showed no beneficial effects over time on any of the outcome measures. CONCLUSION:This study showed no effects. The negative results in this study compared to the study that has been carried out in the US might be explained by the translation, adaptation, and shortening of the intervention used in the US, and a different social context. In addition, the results might be explained by the lack of room for improvement and by experiencing the intervention as too much of a burden. Furthermore, improving physical health might only be effective if the physical exercises are of moderate-to-high-intensity and are tailored in accordance with participants' preferences and needs. For future studies, because dyads often commented positively about the pleasure and support they received, it might also be valuable to measure quality of life outcomes such as relationship quality, pleasure, and self-esteem in dyadic focused interventions.
journal_name
Clin Interv Agingjournal_title
Clinical interventions in agingauthors
Prick AE,de Lange J,Scherder E,Twisk J,Pot AMdoi
10.2147/CIA.S95789subject
Has Abstractpub_date
2016-03-31 00:00:00pages
383-95eissn
1176-9092issn
1178-1998pii
cia-11-383journal_volume
11pub_type
杂志文章,随机对照试验abstract:PURPOSE:In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA), Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs) and their family caregivers (F...
journal_title:Clinical interventions in aging
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2147/CIA.S60838
更新日期:2014-04-10 00:00:00
abstract:BACKGROUND:Satisfaction with treatment is considered a relevant factor for assessing results in clinical practice. However, when assessing satisfaction in dependent patients, the opinion of their caregivers becomes crucial, since implicit in satisfaction is the degree of caregiver involvement, of adherence to treatment...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S83086
更新日期:2015-06-17 00:00:00
abstract::Frailty is a common and important geriatric syndrome characterized by age-associated declines in physiologic reserve and function across multiorgan systems, leading to increased vulnerability for adverse health outcomes. Two major frailty models have been described in the literature. The frailty phenotype defines frai...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S45300
更新日期:2014-03-19 00:00:00
abstract::The increasingly aged population worldwide means more people are living with chronic diseases, reduced autonomy, and taking various medications. Health professionals should take these into consideration when managing dermatological problems in elderly patients. Accordingly, current research is investigating the dermat...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S96232
更新日期:2016-02-12 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine the relationship between hypothesized pain behaviors in the elderly and a measurement model of pain derived from the Minimum Data Set-Resident Assessment Instrument (MDS-RAI) 2.0 items. METHODS:This work included a longitudinal cohort recruited from Medicare-certif...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S29656
更新日期:2012-01-01 00:00:00
abstract:Purpose:The study aimed to investigate the association between body composition and frailty in elder inpatients. Patients and Methods:This is a cross-sectional study including 656 elder inpatients (275 females and 381 males) aged ≥65 years, from department of geriatrics of Zhejiang Hospital between January 2018 and Ma...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S243211
更新日期:2020-03-04 00:00:00
abstract::Apligraf (Organogenesis, Canton, MA) is a bi-layered bioengineered skin substitute and was the first engineered skin US Food and Drug Administration (FDA)-approved to promote the healing of ulcers that have failed standard wound care. Constructed by culturing human foreskin-derived neonatal fibroblasts in a bovine typ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/ciia.2007.2.1.93
更新日期:2007-01-01 00:00:00
abstract:Background:Aging decreases osteogenic ability, inducing harmful effects on the bone extracellular matrix (ECM), while exercise training has been indicated as a tool to counteract bone disorders related to advancing age. The modulation of bone ECM is regulated by several types of matrix metalloproteinase (MMP); however,...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S276518
更新日期:2021-01-08 00:00:00
abstract::The most compelling reason and primary goal of treating actinic keratoses is to prevent malignant transformation into invasive squamous cell carcinoma, and although there are well established guidelines outlining treatment modalities and regimens for squamous cell carcinoma, the more commonly encountered precancerous ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S31930
更新日期:2013-01-01 00:00:00
abstract::The use of atypical antipsychotic drugs in the elderly has become wider and wider in recent years; in fact, these agents have novel receptor binding profiles, good efficacy with regard to negative symptoms, and reduced extrapyramidal symptoms. However, in recent years, the use of both conventional and atypical antipsy...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S63942
更新日期:2014-08-16 00:00:00
abstract:BACKGROUND:The aim of this study was to examine the trend in increasing life expectancy in relation to heart attack and cardiac catheterization. METHODS:A retrospective study of very elderly patients over 90 years of age (study group) and between 70 and 79 years of age (control group) with myocardial infarction and ac...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S29045
更新日期:2012-01-01 00:00:00
abstract:Purpose:In this cross-sectional study, three clinical tools, the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI), for predicting primary osteoporosis (OP) were compared and ideal thresholds for omission of screening ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S145741
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:Vascular dementia (VaD) is a challenging illness that affects the lives of older adults and caregivers. It is unclear how multiple vascular risk factor exposures (polyvascular disease) affect VaD. PURPOSE:To determine the relationship between multiple vascular risk exposures, as counted on an index in cases...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S28143
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of chronic obstructive pulmonary disease (COPD) on left ventricular (LV) diastolic function in hospitalized elderly patients. METHODS:This was a case-control observational study of 148 consecutive hospitalized elderly patients (≥65 years old): 73 subjects without COPD as controls and 7...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S71878
更新日期:2014-12-19 00:00:00
abstract:Objective:The aim of this study was to compare the perceived oral health of elderly persons and the clinical reality of their oral status. Background:Persons aged over 60 have considerable need for oral health care; a need that increases over time. However, this population appears to be unaware of their state of oral ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S204533
更新日期:2019-06-28 00:00:00
abstract:OBJECTIVE:The Neuropsychiatric Inventory (NPI) is one of the most commonly used assessment scales for assessing symptoms in people with dementia and other neurological disorders. This paper analyzes its conceptual framework, measurement mode, psychometric properties, and merits and problems. METHOD:All articles discus...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S63504
更新日期:2014-07-08 00:00:00
abstract:Background:Functional dependence (FD) and vitamin D deficiency are common conditions in older adults. However, little is known about the relationship between FD and serum vitamin D status in centenarians. The current study was designed to evaluate the prevalence of FD and examine its relationship with serum vitamin D s...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S182318
更新日期:2018-10-17 00:00:00
abstract:PURPOSE:The purpose of this study is to compare the efficacy and safety of one-site and two-site combined phacotrabeculectomy with foldable posterior chamber intraocular lens implantation. METHODS:Thirty-four patients (41 eyes) with glaucoma and cataract were randomly assigned to undergo either a one-site (22 eyes) or...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S89401
更新日期:2015-08-24 00:00:00
abstract::Bazedoxifene, a novel selective estrogen receptor modulator, has been developed to have favorable effects on bone and the lipid profile while minimizing stimulation of uterine or breast tissues. Two large Phase III clinical trials showed that bazedoxifene, as well as raloxifene, increased bone mineral density, decreas...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S15711
更新日期:2011-01-01 00:00:00
abstract:Background:Physical exercise is associated with decreased cardiovascular disease (CVD) risk, but recent large-scale trials suggest that exercise alone is insufficient to reduce CVD events in high-risk older adults. Purpose:This pilot randomized clinical trial aimed to collect critical data on feasibility, safety, and ...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S222655
更新日期:2019-10-23 00:00:00
abstract:OBJECTIVE:We studied the effect of sustained virologic response (SVR) after treatment with pegylated-interferon (PEG-IFN) plus ribavirin on the development of liver cirrhosis in elderly patients with chronic hepatitis C (CHC). PATIENTS AND METHODS:This retrospective study enrolled 145 elderly CHC patients (aged ≥65 ye...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S97242
更新日期:2016-03-17 00:00:00
abstract:Background:Both aortic valve stenosis and aortic stiffness are moderators of arterio ventricular coupling and independent predictors of cardiovascular morbidity and mortality. Studies on the effect of transcatheter aortic valve implantation (TAVI) on aortic functional properties are limited. We performed a study to inv...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S211328
更新日期:2019-08-02 00:00:00
abstract:Purpose:The aim of the study was to evaluate the impact of inertial training on upper and lower extremity strength in the elderly. The study also assessed the influence of inertial training on their independence, balance, and speed and quality of gait. Methods:Twenty physically inactive older residents of a nursing ho...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,随机对照试验
doi:10.2147/CIA.S234299
更新日期:2020-02-07 00:00:00
abstract:Objective:Urticaria is a mast cell-related disease caused severe itching and the lifetime prevalence of urticaria is about 20% in general population. Our purpose is to evaluate risk of urticaria in geriatric stroke patients received influenza vaccination (IV). Methods:In a cohort of 192,728 patients with newly diagnos...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S228324
更新日期:2019-11-26 00:00:00
abstract:Background:Disc degeneration (DD) is one of the common diseases worldwide, which deeply influences normal life and leads to excruciating pain. However, an effective treatment for DD is still not identified. Method:The present study systemically examined the effect of melatonin on annulus fibrosus (AF) cells of patient...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S193765
更新日期:2019-03-28 00:00:00
abstract::Adverse drug reaction (ADR) risk-prediction models for use in older adults have been developed, but it is not clear if they are suitable for use in clinical practice. This systematic review aimed to identify and investigate the quality of validated ADR risk-prediction models for use in older adults. Standard computeri...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S65475
更新日期:2014-09-19 00:00:00
abstract:PURPOSE:Cardiovascular diseases are the leading cause of death and disability worldwide. Among these diseases, heart failure (HF) and acute myocardial infarction (AMI) are the most common causes of hospitalization. Therefore, readmission for HF and AMI is receiving increasing attention. Several socioeconomic factors co...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/CIA.S71165
更新日期:2015-01-12 00:00:00
abstract::Lumbar kyphosis and the decreased mobility of the lumbar spine increase the risk of falls and impair both the quality of life and the ability to perform activities of daily living. However, in the elderly Japanese population, little is known about the age-related changes and sex-related differences in muscle strength,...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S113352
更新日期:2017-02-20 00:00:00
abstract:PURPOSE:This paper examines the influence of age on several attributes of sensorimotor performance while performing a reaching task. Our hypothesis, based on previous studies, is that aged persons will show differences in one or more of the attributes of sensorimotor performance. PATIENTS AND METHODS:Fifty-one subject...
journal_title:Clinical interventions in aging
pub_type: 杂志文章
doi:10.2147/CIA.S45900
更新日期:2013-01-01 00:00:00
abstract::Type 2 diabetes mellitus affects 5.9% of the world adult population, with older people and some ethnic groups disproportionately affected. Treatment of older people with diabetes differs in many ways from that in younger adults since the majority have type 2 disease and are at particular risk of macrovascular rather t...
journal_title:Clinical interventions in aging
pub_type: 杂志文章,评审
doi:10.2147/cia.s3142
更新日期:2009-01-01 00:00:00