Metastatic renal cell carcinoma to the pituitary gland presenting with hypopituitarism.

abstract：:Although it is well known that growth hormone may influence protein metabolism, few investigations have been undertaken on serum protein levels in acromegaly; recently hypoglobulinemia has been observed in this endocrine disorder. In 28 acromegalic patients and 56 control subjects sera have been analyzed for total pro...

journal_title：Journal of endocrinological investigation

authors： Federspil G,Vettor R,Bossi A,Sicolo N

更新日期：1979-04-01 00:00:00

abstract：:Pituitary adenomas are common neoplasms requiring medical and/or surgical treatment when associated with hormonal hypersecretion. Treatment of non-functioning pituitary adenomas is necessary when symptoms of mass effect or hormonal deficits occur. However, therapeutic options, including surgical resection and/or radio...

journal_title：Journal of endocrinological investigation

authors： Ballian N,Chrisoulidou A,Nomikos P,Samara C,Kontogeorgos G,Kaltsas GA

更新日期：2007-09-01 00:00:00

abstract：:Two radioimmunological techniques for the measurement of anti-alpha-galactosyl (anti-Gal) antibodies were developed and we demonstrated that this antibody is present in the serum of most untreated patients with Graves' disease, thyroid-associated ophthalmopathy (TAO) and autoimmune thyroiditis. Thyrotropin-binding inh...

journal_title：Journal of endocrinological investigation

authors： Winand RJ,Winand-Devigne J,Cox C,Caulier C,Meurisse M

更新日期：1995-11-01 00:00:00

abstract：PURPOSE:Hashimoto's thyroiditis (HT) is often associated with rheumatic disorders (arthritis, etc.), but many HT patients report non-specific rheumatic signs and symptoms in the absence of clinically evident rheumatic diseases. Aim of this study was to evaluate the prevalence of non-specific rheumatic manifestations (R...

journal_title：Journal of endocrinological investigation

authors： Giuffrida G,Bagnato G,Campennì A,Giovinazzo S,Keller KP,Alibrandi A,Roberts WN,Trimarchi F,Ruggeri RM

更新日期：2020-01-01 00:00:00

abstract：:In 1939 Alan Turing, a major scholar in the field of mechanical computation, described a system whose computational power was beyond that of a discrete, finite state machine (Turing Machine). The composition of this system was likely the first example of what is now called an hybrid computational system. Since then, d...

journal_title：Journal of endocrinological investigation

authors： Sandri G

更新日期：2004-01-01 00:00:00

abstract：:The cause of a poor response to human menopausal gonadotropin (hMG) remains unexplained. To determine whether aromatase activity of cultured granulosa cells obtained from relatively low estradiol (E2) responders (serum E2 < 1000 pg/ml) to hMG therapy differed from that of good responders (E2 > or = 1000 pg/ml), we pro...

journal_title：Journal of endocrinological investigation

authors： Hurst BS,Zacur HA,Schlaff WD,Berkovitz GD

更新日期：1992-09-01 00:00:00

abstract：:GH response to an iv bolus of growth-hormone-releasing hormone (GHRH 1-44, 2 micrograms/kg iv) was evaluated in 17 prepubertal children with total GH deficiency (GHD), 6 with partial GHD and in 7 prepubertal normal but short children tested as control. GH response to conventional pharmacological (insulin and arginine ...

journal_title：Journal of endocrinological investigation

authors： Bozzola M,Tatò L,Cisternino M,Nava C,Valtorta A,Chiesa M,Severi F,Gaburro D

更新日期：1986-12-01 00:00:00

abstract：:To investigate the impact of obstructive sleep apnea syndrome (OSAS) on testosterone levels and on the main parameters of the metabolic syndrome in abdominally obese men, 15 male subjects with abdominal obesity phenotype and polysomnographic diagnosis of OSAS (OB-OSAS) and 15 controls matched for age and anthropometri...

journal_title：Journal of endocrinological investigation

authors： Gambineri A,Pelusi C,Pasquali R

更新日期：2003-06-01 00:00:00

abstract：PURPOSE:Few examples of the involvement of a single gene in idiopathic short stature have been described until now. Our aim was to identify the causative gene of proportionate short stature in a large family showing co-segregation of the phenotype with the reciprocal translocation t(10;15)(q22;q24). METHODS:FISH mappi...

journal_title：Journal of endocrinological investigation

authors： Crippa M,Giangiobbe S,Villa R,Bestetti I,De Filippis T,Fatti L,Taurino J,Larizza L,Persani L,Bellini F,Finelli P,Bonati MT

更新日期：2018-08-01 00:00:00

abstract：:It has been shown that the antithyroid drug methimazole (MMI) may affect B cells and possibly accessory cell function. In the present study we investigated in detail the effects of MMI on T cell in vitro proliferation. The following variables were evaluated: T cell proliferation following stimulation with phytohemaggl...

journal_title：Journal of endocrinological investigation

authors： Bagnasco M,Venuti D,Ciprandi G,Pesce G,Paolieri F,Canonica GW

更新日期：1990-06-01 00:00:00

abstract：:The occurrence of a genetic background in the etiology of polycystic ovarian syndrome (PCOS) represents the rational basis to postulate the existence of a male PCOS equivalent. Hormonal and metabolic abnormalities have been described in male relatives of women with PCOS. These males also have a higher prevalence of ea...

journal_title：Journal of endocrinological investigation

authors： Cannarella R,Condorelli RA,Mongioì LM,La Vignera S,Calogero AE

更新日期：2018-01-01 00:00:00

abstract：:Up to now, the diagnosis of silent corticotroph cell pituitary adenomas has been made only on histopathological basis. In this paper we describe 6 women affected with pituitary adenomas, without evident clinical features of hypercortisolism, in whom retrospective data suggested the possibility of clinically diagnosing...

journal_title：Journal of endocrinological investigation

authors： Ambrosi B,Colombo P,Bochicchio D,Bassetti M,Masini B,Faglia G

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Adiponectin has emerged over the last decade as a key adipokine linking obesity, insulin resistance, and Type 2 diabetes. However, the molecular mechanisms controlling adiponectin expression in adipose tissue are not fully elucidated. Furthermore, increasing evidence indicates that peroxisome proliferator-ac...

journal_title：Journal of endocrinological investigation

authors： Kouidhi S,Jarboui S,Marrakchi R,Froidevaux MS,Seugnet I,Abid H,Bchir F,Brahem M,Demeneix B,Guissouma H,Elgaaied AB

更新日期：2011-02-01 00:00:00

abstract：PURPOSE:Intravenous glucocorticoids (ivGCs) given as 12-weekly infusions are the first-line treatment for moderate-to-severe and active Graves' orbitopathy (GO), but they are not always effective. In this study, we evaluated whether response at 6 weeks correlated with outcomes at 12 (end of intervention) and 24 (follow...

journal_title：Journal of endocrinological investigation

authors： Bartalena L,Veronesi G,Krassas GE,Wiersinga WM,Marcocci C,Marinò M,Salvi M,Daumerie C,Bournaud C,Stahl M,Sassi L,Azzolini C,Boboridis KG,Mourits MP,Soeters MR,Baldeschi L,Nardi M,Currò N,Boschi A,Bernard M,von Arx

更新日期：2017-05-01 00:00:00

abstract：:The in vivo suppressive effect of glucose and insulin on plasma free fatty acid concentrations was investigated in obese subjects with (n = 6) and without (n = 6) Type 2 (non-insulin-dependent) diabetes mellitus during a 4h-hyperglycemic glucose clamp (about 11.2 mmol/l). Somatostatin was infused (250 micrograms/h) du...

journal_title：Journal of endocrinological investigation

authors： Zancanaro C,Cigolini M,Bonora E,Moghetti P,Querena M,Muggeo M

更新日期：1990-01-01 00:00:00

abstract：UNLABELLED:The aim of this study was to assess the behaviour of insulin sensitivity and insulin resistance (IR) indexes in a group of obese adolescents with Type 2 diabetes mellitus (T2DM) in comparison to obese adolescents without diabetes and normal controls, moreover to compare these parameters with the cardiac auto...

journal_title：Journal of endocrinological investigation

authors： Cerutti F,Rabbia F,Rabbone I,Bobbio A,Ignaccolo MG,Greco G,Bertello MC,Mulatero P,Veglio F,Pacini G

更新日期：2010-09-01 00:00:00

abstract：:We describe a unique case of spontaneous resolution of hyperparathyroidism in a lady with combined parathyroid adenoma and prolactinoma, raising the possibility of underlying multiple endocrine neoplasia (MEN) 1 syndrome. We also discuss the mechanism and natural history of such spontaneous remission. ...

journal_title：Journal of endocrinological investigation

authors： Baskar V,Kamalakannan D,Singh BM,Odum J

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Bone marrow mesenchymal stem cells (MSC) mediate their protection by paracrine mechanism under ischemic conditions and anoxic pre-conditioning (AP) of MSC strongly enhances their survival and regenerative capacity. However, there is no report about the therapeutic potency of MSC transplantation on diabetic c...

journal_title：Journal of endocrinological investigation

authors： Li JH,Zhang N,Wang JA

更新日期：2008-02-01 00:00:00

abstract：:The aim of our study was to investigate the effects of estradiol (E2) and/or progesterone (P4) bilateral ovariectomized rats on gene expressions of adenylyl cyclases (AC2, AC4, AC6, AC9). Non-pregnant (NP) Wister rats (between post-natal 10 and 12 weeks) and normal pregnant rats (between postnatal 10 and 14 weeks) wer...

journal_title：Journal of endocrinological investigation

authors： Asano K,Okawa T,Matsuoka I,Suzuki Y,Sato A

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the possible association of insulin-like growth factor-1 (IGF-1) with the pathogenesis of non-functioning adrenocortical adenomas (NFAs). METHODS:This study included 50 female patients (mean age 54 years) with NFAs, 55 patients (mean age 48 years; 20 male, 35 female) wi...

journal_title：Journal of endocrinological investigation

authors： Bahadir CT,Ecemis GC,Atmaca H

更新日期：2018-11-01 00:00:00

abstract：:The aim of this study was to investigate the effects of age, duration of diabetes, sex and ICA (Islet cell cytoplasmic antibody) on beta-cell reserves and to develop a model within the first 2 years of Type 1 diabetes. Beta-cell reserve is evaluated as fasting (FCp) and 1 mg i.v. glucagon stimulated C-peptide (SCp) le...

journal_title：Journal of endocrinological investigation

authors： Altuntas Y

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:Primary hyperparathyroidism has deleterious effects on health and causes nephrolithiasis and osteoporosis. However, it remains unclear whether parathyroidectomy benefits kidney function among patients with primary hyperparathyroidism. METHODS:In this retrospective study, patients with primary hyperparathyroidi...

journal_title：Journal of endocrinological investigation

authors： Liang CC,Yeh HC,Lo YC,Chou CY,Yen TH,Tsai HC,Hsu SP,Kuo CC

更新日期：2020-07-29 00:00:00

abstract：PURPOSE:This study investigated the relationship between seasonal variations in 25-hydroxyvitamin D (25(OH)D) levels and growth in prepubertal children during both the pretreatment year and the first year of GH treatment. METHODS:The study included 249 short prepubertal children with a broad range of GH secretion, GH(...

journal_title：Journal of endocrinological investigation

authors： Andersson B,Swolin-Eide D,Kriström B,Gelander L,Magnusson P,Albertsson-Wikland K

更新日期：2015-12-01 00:00:00

abstract：AIM:This 3-month study compared the effect on overall glycemic control of adding biphasic insulin aspart 30 (BIAsp30) and premixed human insulin 30/70 (BHI30) to metformin (met) in insulin-naïve, obese patients (30 males/20 females) with Type 2 diabetes (T2DM). MATERIAL/SUBJECTS: At baseline, patients had a mean age of...

journal_title：Journal of endocrinological investigation

authors： Velojic-Golubovic M,Mikic D,Pesic M,Dimic D,Radenkovic S,Antic S

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Aldosterone and the mineralocorticoid receptor (MR) play a major role in sodium balance and blood pressure control. They are also involved in adipocyte metabolism. The aim of this study was to analyze the association between the MR p.I180V polymorphism with hypertension and markers of cardiovascular ris...

journal_title：Journal of endocrinological investigation

authors： Fernandes-Rosa FL,Bueno AC,de Souza RM,de Castro M,dos Santos JE,Foss MC,Zennaro MC,Bettiol H,Barbieri MA,Antonini SR

更新日期：2010-07-01 00:00:00

abstract：:Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, a...

journal_title：Journal of endocrinological investigation

authors： Vermiglio F,Lo Presti VP,Finocchiaro MD,Battiato S,Grasso L,Ardita FV,Mancuso A,Trimarchi F

更新日期：1992-02-01 00:00:00

abstract：:The activities of total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were measured in cancerous and non-cancerous adjacent tissues from 15 patients with follicular thyroid cancer containing single nodule. SOD and GSH-Px activities were found lower but malondialdehyde levels hi...

journal_title：Journal of endocrinological investigation

authors： Durak I,Bayram F,Kavutcu M,Canbolat O,Oztürk HS

更新日期：1996-05-01 00:00:00

abstract：:The effects of estriol on serum prolactin (PRL) and LH levels, on the pituitary response to TRH and LHRH and on the synthesis and release of PRL from the anterior pituitary gland were investigated in female rats. The increase of serum PRL levels after estradiol administration was found to be associated with an increas...

journal_title：Journal of endocrinological investigation

authors： Diaz MC,Seilicovich A,Duvilanski BH,Siseles N,Lasaga M,Debeljuk L

更新日期：1989-01-01 00:00:00

abstract：:The 24-h profiles of plasma cortisol (F), 11-beta-hydroxyandrostenedione (11OHAD), androstenedione (AD), dehydroisoandrosterone (DHEA) and testosterone (T) were obtained simultaneously in 11 normal males sampled at 15-min intervals. The data were submitted to a detailed quantitative analysis including the estimation o...

journal_title：Journal of endocrinological investigation

authors： Lejeune-Lenain C,Van Cauter E,Désir D,Beyloos M,Franckson JR

更新日期：1987-06-01 00:00:00

abstract：:Abnormal nutritional status is an increasingly common complication in developed countries and, as reproductive age women are a part of this trend, the effect of maternal obesity on the pregnancy and neonate must be investigated. Pregestational obesity or overweight condition or an excessive gestational weight gain can...

journal_title：Journal of endocrinological investigation

authors： Triunfo S,Lanzone A

更新日期：2014-04-01 00:00:00