Abstract：
:Abnormal nutritional status is an increasingly common complication in developed countries and, as reproductive age women are a part of this trend, the effect of maternal obesity on the pregnancy and neonate must be investigated. Pregestational obesity or overweight condition or an excessive gestational weight gain can be an independent risk factor for feto-maternal complications and long-term risks in adult life for the fetus. The selected risks include infertility, miscarriage, congenital anomalies, hypertensive disorders, gestational diabetes, intrauterine fetal death, macrosomia, and delivery complications. From an etiological point of view, the causes of the adverse outcomes include maternal body habitus, proinflammatory state of obesity, and metabolic dysfunction. Actually, a weight management guidance for obese pregnant women is limited, recommending a gain between 5 and 9 kg during the pregnancy period, while weight loss is discouraged. Mainly, therapeutic approach is prevention using specific programs of reducing weight before pregnant status. In addition, mechanistic studies, in animal models especially, have identified potential areas for intervention which might limit adverse risk factors for obesity from mothers to infants during pregnancy. In this article, a review of the literature on selected obstetrical risks associated with maternal overweight and obesity has been performed and both the target prevention and management strategies have been assessed.
journal_name
J Endocrinol Investjournal_title
Journal of endocrinological investigationauthors
Triunfo S,Lanzone Adoi
10.1007/s40618-014-0058-9subject
Has Abstractpub_date
2014-04-01 00:00:00pages
323-9issue
4eissn
0391-4097issn
1720-8386journal_volume
37pub_type
杂志文章,评审abstract：PURPOSE:The aim of this study was to evaluate the prevalence and risk factors associated with female sexual dysfunction (FSD) in young women with type 1 diabetes treated with different intensive insulin regimens. METHODS:Type 1 diabetic women aged 18-35 years were included in this study if they had stable couple relat...
journal_title：Journal of endocrinological investigation
pub_type： 临床试验,杂志文章
doi：10.1007/s40618-016-0542-5
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:Although men with spinal cord injury (SCI) exhibit a prostate volume significantly smaller compared to age-matched able-bodied men, the independent association of lower prostate volume with its putative determinants has never been analyzed in this population. This study was designed to identify variables indepe...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/s40618-020-01243-3
更新日期：2020-11-01 00:00:00
abstract：:We evaluated the 24-h profile of serum melatonin (MT) in 16 patients with Cushing's syndrome (11 pituitary- and 5 adrenal-dependent) aged 38.1 +/- 13.8 years and in 19 patients with acromegaly due to GH-secreting pituitary adenoma aged 52 +/- 11.9 years. Thirty-three healthy subjects aged 30 +/- 7 years and 26 healthy...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349691
更新日期：1995-01-01 00:00:00
abstract：:The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a signif...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03350367
更新日期：1978-04-01 00:00:00
abstract：:A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. Cardiac and adrenergic diseases were excluded. The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; ho...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349636
更新日期：1990-11-01 00:00:00
abstract：PURPOSE:To compare the histopathological features and the outcomes of the follicular variant and classical variant of papillary thyroid carcinoma. MATERIAL AND THE METHODS:Demographic data, histopathological features (tumor size, thyroid capsule invasion, extrathyroidal extension, vascular invasion and multicentricity...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/s40618-015-0376-6
更新日期：2015-12-01 00:00:00
abstract：:Fifty-seven (35.6%) of 160 patients with papillary thyroid carcinoma had lymph node metastases at the primary treatment. Children and adolescents were most frequently affected (69.2%), followed by the age group of 21-40-year olds (38.8%). Those older than 40 had the lowest incidence of lymph node metastases (29.6%; p ...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03346863
更新日期：1991-07-01 00:00:00
abstract：:Cortistatin (CST), a 17-amino acid peptide partially homologous to somatostatin (SRIF), has been originally isolated from the cerebral cortex and recently found in monocytes and macrophages of the immune system. CST binds all 5 SRIF receptors, as well the GH secretagogue (GHS)/ghrelin receptors. CST exerts sleep promo...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03347348
更新日期：2003-08-01 00:00:00
abstract：:During a systematic study of women with idiopathic galactorrhea, we observed several patients with normal random serum prolactin (PRL) levels and normal menses, but abnormal sellar tomograms characteristic of a pituitary adenoma. To test the hypothesis that these women might have intermittent PRL hypersecretion, we st...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03348450
更新日期：1984-10-01 00:00:00
abstract：:To evaluate the influence of chronological age and pubertal development on the hypothalamus-pituitary-adrenal (HPA) axis response to stress, we studied the possible correlations between male pubertal characteristics and salivary cortisol (C), DHEAS and the DHEAS/C ratio before (pre-stress) and after acute exercise-str...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03347373
更新日期：2006-10-01 00:00:00
abstract：:The aim of this study was to assess the early insulin secretion and insulin action of healthy non-diabetic Hispanic-Mexican subjects with and without family history of Type 2 diabetes (FHD). One hundred and twenty non-relative subjects were compared against 115 first-degree relatives of individuals with Type 2 diabete...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03343898
更新日期：2001-09-01 00:00:00
abstract：:A strong relationship was previously described between the nocturnal oscillations of plasma renin activity (PRA) and the sleep cycles, with levels of PRA that increase during non rapid eye movement sleep and decrease during rapid eye movement sleep. This study was designed to determine whether ritanserin, a 5-hydroxyt...
journal_title：Journal of endocrinological investigation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF03349016
更新日期：1996-09-01 00:00:00
abstract：:Unfortunately, the author name and his affiliation were published in the original publication. They have now been removed. ...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,已发布勘误
doi：10.1007/s40618-019-01012-x
更新日期：2019-02-01 00:00:00
abstract：:We studied 8 insulin dependent stable young diabetics with a mean age of 20 yr. Each patient received 10 mg of diazepam orally after with drawing the baseline blood sample. Subsequent samples were obtained at 30 min intervals for 150 min. The oral administration of diazepam resulted in a significant increase in serum ...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349471
更新日期：1982-05-01 00:00:00
abstract：:Endocrine changes have been reported in treated epileptic subjects, who often exhibit sexual dysfunctions, but the endocrine effects of single antiepileptic drugs have not been completely elucidated. In this study we have investigated the influence of phenobarbital (PB) on adenopituitary function and on peripheral sex...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03347145
更新日期：1987-02-01 00:00:00
abstract：PURPOSE:Although vitamin D is reportedly associated with various cancers, the association between vitamin D and thyroid cancer is indefinite. We aimed to investigate whether this association applies to thyroid cancer (TC). METHODS:A total of 276 Chinese Han people were recruited in a current matched case-control study...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,meta分析
doi：10.1007/s40618-018-0853-9
更新日期：2018-10-01 00:00:00
abstract：: ...
journal_title：Journal of endocrinological investigation
pub_type： 历史文章,杂志文章
doi：10.1007/s40618-018-0896-y
更新日期：2018-12-01 00:00:00
abstract：:Rats bearing mammosomatotropic tumors have raised insulin but lowered glucose concentrations. To determine if growth hormone (GH) secreted by these tumors causes insulin antagonism, pancreatic suppression tests utilizing infusions (per kg per min) of glucose (8 mg), insulin (200 ng) and somatostatin (1.4 micrograms) f...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03346996
更新日期：1987-12-01 00:00:00
abstract：:The present study investigated whether trophoblast, decidua and fetal membranes express nerve growth factor (NGF) mRNA and peptide. Tissue specimens were collected in the first and third trimester of pregnancy from women undergoing voluntary pregnancy interruption (no.= 6; from 8 to 12 gestational weeks) and from wome...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03344105
更新日期：2006-04-01 00:00:00
abstract：:Hypoparathyroidism cannot be cured by oral or intravenous calcium supplements. Using molecular biology techniques to induce the production of PTH is an ideal option to treat hypoparathyroidism. In this study, we established a recombinant plasmid encoding a mutant preproPTH with a skeletal muscle creatine kinase promot...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.3275/7966
更新日期：2012-05-01 00:00:00
abstract：:Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：AIM:The optimal GH regimen, in terms of cost-effectiveness, in children with normal GH immunoreactivity but reduced bioactivity is still debated. METHODS:In 12 GH-deficient (GHD) and 12 bioinactive GH children undergoing GH treatment we evaluated the increase in growth velocity, the difference between target height an...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03347461
更新日期：2011-05-01 00:00:00
abstract：:A technique has been developed with which it has been possible to quantify the output of a wide variety of agonists including catecholamines, glucocorticoids, mineralocorticoids, enkephalins and various peptides, from the adrenal gland in the conscious unrestrained calf; also to investigate responses to electrical sti...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349647
更新日期：1990-12-01 00:00:00
abstract：:Liquid-chromatography - tandem mass spectrometry (LC-MS/MS) is becoming the method of choice for clinical steroid analysis. In most instances, it has the advantage of higher sensitivity, better reproducibility and greater specificity than commercial immunoassay techniques. The method requires only minimal sample prepa...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,评审
doi：10.3275/7843
更新日期：2011-10-01 00:00:00
abstract：:This study was performed to evaluate the antihypercalciuric effect of calcitonin (CT), a potent inhibitor of bone osteoclastic activity, on idiopathic hypercalciuria (IH). Forty-two stone formers were studied: 18 suffered from fasting hypercalciuria (FH), 12 from nonfasting hypercalciuria (NFH) and 12 were normocalciu...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03350171
更新日期：1988-07-01 00:00:00
abstract：:In a 12-yr-old boy growth arrest occurred after severe head trauma. Evaluation of pituitary endocrine function revealed isolated growth hormone (GH) deficiency. Lack of GH response to GH-releasing factor indicated that the responsible lesion was most likely to be localized in the pituitary gland. GH substitution resul...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349069
更新日期：1988-06-01 00:00:00
abstract：:Silver-Russell syndrome (SRS) is both clinically and genetically a heterogeneous congenital disorder. Patients are characterised by severe intrauterine and post-natal growth retardation, dysmorphic facial features and, asymmetry. Various chromosome abnormalities have been associated with the disease, involving most of...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：:To determine whether G proteins are involved in the regulation of mouse placental lactogen-I (mPL-I) and/or mPL-II secretion before midpregnancy, mouse placental tissue from day 7 of pregnancy was dispersed with collagenase, cells were fractionated on a percoll gradient, and the purified trophoblast cells were culture...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03349006
更新日期：1996-09-01 00:00:00
abstract：:Thyroid hormone acts on the oocytes, sperm and embryo during fertilization, implantation and placentation. Both hypothyroidism and hyperthyroidism may influence fertility. However, evidence of the association of hyperthyroidism with infertility is scarce and sometimes conflicting. Thyroid hormone influences human repr...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章,评审
doi：10.1007/s40618-016-0452-6
更新日期：2016-08-01 00:00:00
abstract：:3 alpha-androstanediol glucuronide (3 alpha diolG) is a marker of peripheral tissue androgen metabolism. There are no previous data regarding complete paediatric reference ranges for 3 alpha diolG. In order to obtain reference values for 3 alpha diolG we have measured serum levels of 3 alpha diolG in 283 healthy child...
journal_title：Journal of endocrinological investigation
pub_type： 杂志文章
doi：10.1007/BF03346892
更新日期：1997-03-01 00:00:00
